Abstract：
:The effects of zinc (Zn) deficiency and repeated exposure to cadmium (Cd) on the accumulation and distribution of metallothionein (MT), Cd and Zn in the liver and kidney were studied. Male Sprague-Dawley rats were fed either a Zn-deficient (1 ppm) or a Zn-adequate (40 ppm) diet during the experiment, and the rats were injected subcutaneously with a cadmium chloride solution (1.0 mg Cd/kg of body weight, 5 days a week) for 4 weeks. Cadmium, Zn, and Cd-induced MT concentrations in the liver and kidney were lower in the Zn-deficient rats (-Zn + Cd) than in the Zn-adequate rats (+Zn + Cd), while the content of Cd bound to high molecular weight proteins (HMWP) was greater in the Zn-deficient rats (-Zn + Cd). The Zn bound to Cd-induced MT was reduced to 30% in the liver and to 60% in the kidney of the Zn-deficient rats (-Zn + Cd) as compared with that of the Zn-adequate rats (+Zn + Cd). In the kidney of Zn-deficient rats, exposure to Cd caused a decrease in essential Zn associated with HMWP as compared with that of Zn-adequate rats (+Zn + Cd). Thus, Zn-deficiency affected the distribution of Cd in tissues, MT and HMWP and accelerated substantially Cd-induced Zn-deficiency in the kidney.(ABSTRACT TRUNCATED AT 250 WORDS)
journal_name
Arch Environ Contam Toxicoljournal_title
Archives of environmental contamination and toxicologyauthors
Sato M,Nagai Ydoi
10.1007/BF01055026subject
Has Abstractpub_date
1989-07-01 00:00:00pages
587-93issue
4eissn
0090-4341issn
1432-0703journal_volume
18pub_type
杂志文章abstract：:Six prairie grain farmers were monitored for pesticide exposure and related adverse effects while they mixed and/or sprayed carbofuran (Furadan 480F) with ground rig application equipment to control grasshoppers in southern Alberta, Canada. Dermal exposure was estimated with Tegaderm patches placed at seventeen locati...
journal_title：Archives of environmental contamination and toxicology
pub_type： 杂志文章
doi：10.1007/BF01056087
更新日期：1990-03-01 00:00:00
abstract：:Sediment and water samples collected from 8 sites of the Yangtze River in Nanjing section were characterized with 31 congeners of polychlorodibenzothiophenes (PCDTs). Concentrations and percentage compositions of these PCDTs in water and sediments were analyzed by gas chromatography-mass spectrometry. Results showed t...
journal_title：Archives of environmental contamination and toxicology
pub_type： 杂志文章
doi：10.1007/s00244-015-0159-2
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abstract：:Recently, there is increasing interest in the microbial degradation of endocrine disruptors. This study was conducted to show the isolation and property of bacteria having bisphenol A (BPA) biodegradability in river water and to identify the difference of BPA degradation under aerobic and anaerobic conditions. Three r...
journal_title：Archives of environmental contamination and toxicology
pub_type： 杂志文章
doi：10.1007/s00244-002-1209-0
更新日期：2002-10-01 00:00:00
abstract：:Mercury concentrations in fish were investigated downstream from a newly impounded subtropical reservoir in August 2008. After 6-7 months of reservoir impoundment, mean mercury concentration in fish from downstream is significantly increased by 1.9 times. Not only carnivorous fish but also benthic fish had significant...
journal_title：Archives of environmental contamination and toxicology
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更新日期：2017-11-01 00:00:00
abstract：:The United States Environmental Protection Agency has defined national in-stream water-quality criteria (WQC) for 157 pollutants. No WQC to protect aquatic life exist for total dissolved solids (TDS). Some water-treatment processes (e.g., pH modifications) discharge wastewaters of potentially adverse TDS into freshwat...
journal_title：Archives of environmental contamination and toxicology
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journal_title：Archives of environmental contamination and toxicology
pub_type： 杂志文章
doi：10.1007/s002440010147
更新日期：2001-01-01 00:00:00
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journal_title：Archives of environmental contamination and toxicology
pub_type： 杂志文章
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更新日期：1999-07-01 00:00:00
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journal_title：Archives of environmental contamination and toxicology
pub_type： 杂志文章
doi：10.1007/BF01055540
更新日期：1980-01-01 00:00:00
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pub_type： 杂志文章
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更新日期：1997-05-01 00:00:00
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journal_title：Archives of environmental contamination and toxicology
pub_type： 杂志文章
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更新日期：2013-11-01 00:00:00
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journal_title：Archives of environmental contamination and toxicology
pub_type： 杂志文章
doi：10.1007/BF01055345
更新日期：1991-08-01 00:00:00
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journal_title：Archives of environmental contamination and toxicology
pub_type： 杂志文章
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更新日期：2011-02-01 00:00:00
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journal_title：Archives of environmental contamination and toxicology
pub_type： 杂志文章
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更新日期：2010-04-01 00:00:00
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journal_title：Archives of environmental contamination and toxicology
pub_type： 杂志文章
doi：10.1007/s00244-005-8218-8
更新日期：2007-04-01 00:00:00
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journal_title：Archives of environmental contamination and toxicology
pub_type： 杂志文章
doi：10.1007/s00244-003-0172-8
更新日期：2003-08-01 00:00:00
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journal_title：Archives of environmental contamination and toxicology
pub_type： 杂志文章
doi：10.1007/s002449900366
更新日期：1998-08-01 00:00:00
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journal_title：Archives of environmental contamination and toxicology
pub_type： 杂志文章
doi：10.1007/s002449900359
更新日期：1998-07-01 00:00:00
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journal_title：Archives of environmental contamination and toxicology
pub_type： 杂志文章
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journal_title：Archives of environmental contamination and toxicology
pub_type： 杂志文章
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更新日期：1996-07-01 00:00:00
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journal_title：Archives of environmental contamination and toxicology
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更新日期：2008-11-01 00:00:00
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journal_title：Archives of environmental contamination and toxicology
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更新日期：2019-01-01 00:00:00
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journal_title：Archives of environmental contamination and toxicology
pub_type： 杂志文章
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更新日期：1996-01-01 00:00:00
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journal_title：Archives of environmental contamination and toxicology
pub_type： 杂志文章
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更新日期：2012-10-01 00:00:00
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journal_title：Archives of environmental contamination and toxicology
pub_type： 杂志文章
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更新日期：2010-04-01 00:00:00
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journal_title：Archives of environmental contamination and toxicology
pub_type： 杂志文章
doi：10.1007/s00244-012-9754-7
更新日期：2012-07-01 00:00:00
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journal_title：Archives of environmental contamination and toxicology
pub_type： 杂志文章
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更新日期：2002-07-01 00:00:00
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journal_title：Archives of environmental contamination and toxicology
pub_type： 杂志文章
doi：10.1007/s002449900302
更新日期：1998-02-01 00:00:00
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journal_title：Archives of environmental contamination and toxicology
pub_type： 杂志文章
doi：10.1007/s002449900189
更新日期：1997-04-01 00:00:00
