Abstract：
BACKGROUND AND OBJECTIVE:Magnetic resonance-guided laser-induced thermotherapy (MR-LITT) is a minimally invasive technique that shows promise in neuro-oncology because of its superiority in delivering precise minimally invasive thermal energy with minimal collateral damage. In this analysis, we investigate initial data on the effect of MR-LITT on dural-based lesions. METHODS:Five patients were identified with dural-based lesions (4 meningiomas, 1 solitary fibrous tumor) with clear evidence of radiologic progression. In all 5 cases, the tumors were localized to the lateral convexity or paramedian locations in the supratentorial space. All patients received MR-LITT and then a follow-up magnetic resonance imaging scan at 24 hours after treatment, at 1 month, and at each subsequent follow-up visit. Local control of the ablated tumor was evaluated with radiographic follow-up and symptomatic progression-free survival was recorded. RESULTS:Five LITT treatments were performed on 5 patients with an average age of 65.2 years. The average tumor volume was 29.7 cm3 and ablation dosage was 12.4 W. On average, 80% of the pretreatment lesion volume was ablated. The mean follow-up time was 59.3 weeks. In total, 2 patients (1 with an anaplastic meningioma and 1 with a solitary fibrous tumor) had radiographic evidence of disease progression. In the observed time of the 3 patients with no progression, there was a 52% reduction in tumor volume. There were no major perioperative complications. CONCLUSIONS:MR-LITT is a promising technology for dural-based lesion treatment. This initial study demonstrates that MR-LITT is safe and offers several advantages over open surgical treatment. Randomized studies are needed to evaluate its role as a treatment adjunct.
journal_name
World Neurosurgjournal_title
World neurosurgeryauthors
Ivan ME,Diaz RJ,Berger MH,Basil GW,Osiason DA,Plate T,Wallo A,Komotar RJdoi
10.1016/j.wneu.2016.10.037subject
Has Abstractpub_date
2017-02-01 00:00:00pages
162-170eissn
1878-8750issn
1878-8769pii
S1878-8750(16)31025-7journal_volume
98pub_type
杂志文章abstract：OBJECTIVE:To elucidate the role of endoscopic third ventriculostomy (ETV) in patients with secondary and idiopathic communicating hydrocephalus (HCP). METHODS:A series of 36 patients with communicating HCP (21 men and 15 women) were treated by ETV between November 2007 and February 2010. The patients age ranged from 1...
journal_title：World neurosurgery
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doi：10.1016/j.wneu.2011.06.038
更新日期：2012-03-01 00:00:00
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journal_title：World neurosurgery
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abstract：BACKGROUND:Transforaminal endoscopic lumbar discectomy (TELD), a minimally invasive spinal technique, has advantages over open discectomy. Unilateral TELD for disc herniation causing bilateral symptoms is challenging. In this study, we describe a percutaneous endoscopic herniotomy technique by using a unilateral approa...
journal_title：World neurosurgery
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abstract：BACKGROUND:The effect of age on adult brain arteriovenous malformation (AVM) outcomes after stereotactic radiosurgery (SRS) remains unclear. The aim of this study is to compare AVM outcomes between elderly (age ≥60 years) and nonelderly adult patients. METHODS:We retrospectively reviewed pooled data comprising patient...
journal_title：World neurosurgery
pub_type： 杂志文章,多中心研究
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更新日期：2018-11-01 00:00:00
abstract：BACKGROUND:Pediatric cerebral ganglioneuroblastoma is an exceedingly rare tumor. CASE DESCRIPTION:We describe the case of a 4-year-old boy with sudden mental status decline who was found to have a large intracranial lesion with intraventricular extension. CONCLUSION:Management of the case and pathologic findings are ...
journal_title：World neurosurgery
pub_type： 杂志文章,评审
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更新日期：2018-05-01 00:00:00
abstract：BACKGROUND:To retrospectively analyze our clinical data to determine the risk factors for thromboembolism, especially with unruptured posterior circulation coil embolization. METHODS:A total of 53 coil embolization procedures for unruptured posterior circulation aneurysms performed in 53 patients between October 2010 ...
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journal_title：World neurosurgery
pub_type： 杂志文章,meta分析,评审
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更新日期：2020-02-01 00:00:00
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journal_title：World neurosurgery
pub_type： 杂志文章
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更新日期：2020-06-01 00:00:00
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journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2019.02.012
更新日期：2019-06-01 00:00:00
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pub_type： 杂志文章
doi：10.1016/j.wneu.2018.10.002
更新日期：2019-01-01 00:00:00
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journal_title：World neurosurgery
pub_type： 杂志文章
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更新日期：2018-11-01 00:00:00
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journal_title：World neurosurgery
pub_type： 杂志文章
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更新日期：2018-12-01 00:00:00
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journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2015.05.074
更新日期：2015-10-01 00:00:00
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journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2015.10.060
更新日期：2016-03-01 00:00:00
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journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2018.07.151
更新日期：2018-10-01 00:00:00
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journal_title：World neurosurgery
pub_type： 杂志文章,评审
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更新日期：2017-12-01 00:00:00
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journal_title：World neurosurgery
pub_type： 杂志文章,meta分析,评审
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更新日期：2017-06-01 00:00:00
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journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2020.02.158
更新日期：2020-06-01 00:00:00
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journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2018.06.027
更新日期：2018-09-01 00:00:00
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pub_type： 杂志文章
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更新日期：2019-06-01 00:00:00
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doi：10.1016/j.wneu.2018.04.107
更新日期：2018-07-01 00:00:00
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journal_title：World neurosurgery
pub_type： 杂志文章
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更新日期：2018-12-31 00:00:00
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journal_title：World neurosurgery
pub_type： 杂志文章
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更新日期：2018-03-01 00:00:00
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journal_title：World neurosurgery
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更新日期：2018-11-01 00:00:00
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journal_title：World neurosurgery
pub_type： 杂志文章
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更新日期：2018-11-01 00:00:00
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journal_title：World neurosurgery
pub_type： 杂志文章,多中心研究
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更新日期：2016-07-01 00:00:00
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journal_title：World neurosurgery
pub_type： 杂志文章
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更新日期：2019-06-01 00:00:00
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journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2018.07.239
更新日期：2018-11-01 00:00:00
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journal_title：World neurosurgery
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更新日期：2020-06-01 00:00:00
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journal_title：World neurosurgery
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更新日期：2019-08-01 00:00:00
