当前位置： SCI文献检索 > INTERNATIONAL JOURNAL OF CARDIOLOGY期刊下所有文献 > Genetic basis of dilated cardiomyopathy.

Genetic basis of dilated cardiomyopathy.

Abstract：

:Dilated cardiomyopathy is a rare cardiac disease characterized by left ventricular dilatation and systolic dysfunction leading to heart failure and sudden cardiac death. Currently, despite several conditions have been reported as aetiologies of the disease, a large number of cases remain classified as idiopathic. Recent studies determine that nearly 60% of cases are inherited, therefore due to a genetic cause. Progressive technological advances in genetic analysis have identified over 60 genes associated with this entity, being TTN the main gene, so far. All these genes encode a wide variety of myocyte proteins, mainly sarcomeric and desmosomal, but physiopathologic pathways are not yet completely unraveled. We review the recent published data about genetics of familial dilated cardiomyopathy.

journal_name

Int J Cardiol

journal_title

International journal of cardiology

authors

Pérez-Serra A,Toro R,Sarquella-Brugada G,de Gonzalo-Calvo D,Cesar S,Carro E,Llorente-Cortes V,Iglesias A,Brugada J,Brugada R,Campuzano O

doi

10.1016/j.ijcard.2016.09.068

subject

Has Abstract

pub_date

2016-12-01 00:00:00

pages

461-472

eissn

0167-5273

issn

1874-1754

pii

S0167-5273(16)32357-9

journal_volume

224

pub_type

杂志文章,评审

相关文献

INTERNATIONAL JOURNAL OF CARDIOLOGY文献大全
  • Hypertension control in a large multi-ethnic cohort in Amsterdam, The Netherlands: the HELIUS study.

    abstract：OBJECTIVE:Hypertension is a major problem among European ethnic minority groups. We assessed the current situation of hypertension prevalence and its management among a multi-ethnic population in Amsterdam, The Netherlands. METHODS:Data from the HELIUS study were used including 12,974 participants (1871 Ghanaian, 2184...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.ijcard.2015.01.061

    authors： Agyemang C,Kieft S,Snijder MB,Beune EJ,van den Born BJ,Brewster LM,Ujcic-Voortman JJ,Bindraban N,van Montfrans G,Peters RJ,Stronks K

    更新日期：2015-03-15 00:00:00

  • Impact of coronary bypass or stenting on mortality and myocardial infarction in stable coronary artery disease.

    abstract：BACKGROUND:To assess whether coronary bypass (CABG) or stenting reduce the risk of mortality and myocardial infarction (MI) compared with optimal medical therapy (OMT) in stable coronary artery disease (CAD). METHODS:We performed a systematic review and network meta-analysis of contemporary randomized controlled trial...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.ijcard.2020.01.054

    authors： Taglieri N,Bruno AG,Bacchi Reggiani ML,D'Angelo EC,Ghetti G,Bruno M,Palmerini T,Rapezzi C,Galiè N,Saia F

    更新日期：2020-06-15 00:00:00

  • Patients with higher body mass index treated with direct / novel oral anticoagulants (DOAC / NOAC) for atrial fibrillation experience worse clinical outcomes.

    abstract：INTRODUCTION:Due to fixed dosing of direct oral anticoagulants (DOACs), uncertainty exists about their efficacy in a population of obese/overweight patients. PATIENTS AND METHODS:We retrospectively investigated a real-life cohort of 325 DOAC anticoagulated patients with atrial fibrillation [179 receiving dabigatran (5...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.ijcard.2019.10.035

    authors： Lucijanic M,Jurin I,Jurin H,Lucijanic T,Starcevic B,Skelin M,Glasnovic A,Catic J,Jurisic A,Hadzibegovic I

    更新日期：2020-02-15 00:00:00

  • Day case cardiac catheterisation using the Sones technique.

    abstract：:Cardiac catheterisation using the Sones technique was planned as a day case procedure in 855 of 1662 consecutive patients admitted for cardiac catheterisation. Of these, 810 (95%) were discharged the same day. Forty-five (5%) needed overnight hospitalization, 34 for reasons connected with the procedure and 11 for othe...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/0167-5273(89)90034-x

    authors： Murray NH,Rothman MT

    更新日期：1989-07-01 00:00:00

  • Atherosclerotic calcification and intimal medial thickness of the carotid arteries.

    abstract：BACKGROUND AND PURPOSE:Carotid intimal medial thickness (IMT) is a measure of subclinical atherosclerosis and is predictive of future cardiovascular events. The purpose of this study was to determine the significance and magnitude of association between IMT and atherosclerotic calcification of the carotid arteries. ME...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.ijcard.2004.12.039

    authors： Allison MA,Tiefenbrun J,Langer RD,Wright CM

    更新日期：2005-08-03 00:00:00

  • Effectiveness of fixed dose combination medication ('polypills') compared with usual care in patients with cardiovascular disease or at high risk: A prospective, individual patient data meta-analysis of 3140 patients in six countries.

    abstract：AIMS:To conduct a prospective, individual participant data (IPD) meta-analysis of randomised controlled trials comparing a polypill-based approach with usual care in high risk individuals. METHODS AND RESULTS:Three trials comparing polypill-based care with usual care in individuals with CVD or high calculated cardiova...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.ijcard.2015.12.015

    authors： Webster R,Patel A,Selak V,Billot L,Bots ML,Brown A,Bullen C,Cass A,Crengle S,Raina Elley C,Grobbee DE,Neal B,Peiris D,Poulter N,Prabhakaran D,Rafter N,Stanton A,Stepien S,Thom S,Usherwood T,Wadham A,Rodgers A,

    更新日期：2016-02-15 00:00:00

  • Platelet reactivity in patients receiving a maintenance dose of P2Y12-ADP receptor antagonists undergoing elective percutaneous coronary intervention.

    abstract：BACKGROUND:P2Y12-ADP receptor blockade during percutaneous coronary intervention (PCI) is critical to prevent thrombotic events. In patients under chronic P2Y12 blockers, the use of additional loading dose (LD) before an elective PCI is debated. We aimed to investigate the rate of high on-treatment platelet reactivity ...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.ijcard.2016.04.165

    authors： Bonello L,Laine M,Thuny F,Paganelli F,Lemesle G,Roch A,Kerbaul F,Dignat-George F,Berbis J,Frere C

    更新日期：2016-08-01 00:00:00

  • Atrioventricular septal defect: From embryonic development to long-term follow-up.

    abstract：:Atrioventricular septal defect (AVSD) covers a spectrum of heart anomalies with a common atrioventricular connection and has an incidence of 4-5.3 per 10.000 live births. About half of the AVSDs occur in patient with Down syndrome. This review provides a bench to bedside overview of AVSD. Developmental aspects, nomenc...

    journal_title：International journal of cardiology

    pub_type： 杂志文章,评审

    doi：10.1016/j.ijcard.2015.09.081

    authors： Calkoen EE,Hazekamp MG,Blom NA,Elders BB,Gittenberger-de Groot AC,Haak MC,Bartelings MM,Roest AA,Jongbloed MR

    更新日期：2016-01-01 00:00:00

  • Left ventricular volume and wall stress are linked to lung function impairment in COPD.

    abstract：BACKGROUND:Cardiovascular comorbidities are common in chronic obstructive pulmonary disease (COPD). We examined the association between airflow limitation, hyperinflation and the left ventricle (LV). METHODS:Patients from the COPD cohort COSYCONET underwent evaluations including forced expiratory volume in 1 s (FEV1),...

    journal_title：International journal of cardiology

    pub_type： 杂志文章,多中心研究

    doi：10.1016/j.ijcard.2018.02.074

    authors： Alter P,Jörres RA,Watz H,Welte T,Gläser S,Schulz H,Bals R,Karch A,Wouters EFM,Vestbo J,Young D,Vogelmeier CF

    更新日期：2018-06-15 00:00:00

  • Valsartan in heart failure patients previously untreated with an ACE inhibitor.

    abstract：OBJECTIVE:To evaluate the effect on cardiac hemodynamic parameters of valsartan in patients with chronic stable congestive heart failure previously untreated with ACE inhibitors. METHODS:After a 2 to 4 week run-in period, 116 adult outpatients were randomized to receive valsartan 40, 80 or 160 mg twice daily, the ACE ...

    journal_title：International journal of cardiology

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/s0167-5273(98)00149-1

    authors： Mazayev VP,Fomina IG,Kazakov EN,Sulimov VA,Zvereva TV,Lyusov VA,Orlov VA,Olbinskaya LI,Bolshakova TD,Sullivan J,Spormann DO

    更新日期：1998-08-01 00:00:00

  • The role of implantable cardioverter-defibrillators in patients with continuous flow left ventricular assist devices - A meta-analysis.

    abstract：BACKGROUND:Left ventricular assist devices (LVADs) and implantable cardioverter defibrillators (ICD) are each known to improve mortality in patients with advanced congestive heart failure (CHF). If ICDs contribute to improved survival specifically in recipients of LVADs is currently unknown. AIM:To evaluate the impact...

    journal_title：International journal of cardiology

    pub_type： 杂志文章,meta分析

    doi：10.1016/j.ijcard.2016.07.257

    authors： Agrawal S,Garg L,Nanda S,Sharma A,Bhatia N,Manda Y,Singh A,Fegley M,Shirani J

    更新日期：2016-11-01 00:00:00

  • Cardiovascular magnetic resonance-derived intramyocardial hemorrhage after STEMI: Influence on long-term prognosis, adverse left ventricular remodeling and relationship with microvascular obstruction.

    abstract：BACKGROUND:T2 weighted cardiovascular magnetic resonance (CMR) can detect intramyocardial hemorrhage (IMH) after ST-elevation myocardial infarction (STEMI). The long-term prognostic value of IMH beyond a comprehensive CMR assessment with late enhancement (LE) imaging including microvascular obstruction (MVO) is unclear...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.ijcard.2012.05.055

    authors： Husser O,Monmeneu JV,Sanchis J,Nunez J,Lopez-Lereu MP,Bonanad C,Chaustre F,Gomez C,Bosch MJ,Hinarejos R,Chorro FJ,Riegger GA,Llacer A,Bodi V

    更新日期：2013-09-01 00:00:00

  • Ezetimibe inhibits platelet activation and uPAR expression on endothelial cells.

    abstract：PURPOSE:Lipid lowering therapy constitutes the basis of cardiovascular disease therapy. The purpose of this study was to investigate effects of ezetimibe, a selective inhibitor of intestinal cholesterol absorption, on platelets and endothelial cells in an in vitro endothelial cell model. METHODS:After a 24h incubation...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.ijcard.2016.09.122

    authors： Becher T,Schulze TJ,Schmitt M,Trinkmann F,El-Battrawy I,Akin I,Kälsch T,Borggrefe M,Stach K

    更新日期：2017-01-15 00:00:00

  • Brain natriuretic peptide: Much more than a biomarker.

    abstract：:Brain natriuretic peptide (BNP) modulates several biological processes by activating the natriuretic peptide receptor A (NPR-A). Atria and ventricles secrete BNP. BNP increases natriuresis, diuresis and vasodilatation, thus resulting in a decreased cardiac workload. BNP and NT-proBNP, which is the biologically inactiv...

    journal_title：International journal of cardiology

    pub_type： 杂志文章,评审

    doi：10.1016/j.ijcard.2016.07.109

    authors： Calzetta L,Orlandi A,Page C,Rogliani P,Rinaldi B,Rosano G,Cazzola M,Matera MG

    更新日期：2016-10-15 00:00:00

  • Computational analysis of Nitinol stent-graft for endovascular aortic repair (EVAR) of abdominal aortic aneurysm (AAA): Crimping, sealing and fluid-structure interaction (FSI).

    abstract：OBJECTIVES:We evaluate the crimping strain, sealing stress and contact forces on a Nitinol stent deployed in the aorta during endovascular aortic (or aneurysm) repair (EVAR) procedures. Nitinol shape memory effect (SME) is used. We also study the fluid-structure interaction (FSI) of the blood flow on the stented aorta....

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.ijcard.2019.11.091

    authors： Jayendiran R,Nour B,Ruimi A

    更新日期：2020-04-01 00:00:00

  • Surgical repair of post-infarction ventricular septal defect: 19 years of experience.

    abstract：OBJECTIVES:To review our experience of surgical repair of post-infarction ventricular septal defect (VSD). METHODS:In the period 1983-2002, 50 patients underwent repair of VSD. Mean age was 66 years, male sex 52%. Infarct location was anterior in 60% and posterior in 40% of cases. Median interval between rupture and s...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.ijcard.2005.05.007

    authors： Mantovani V,Mariscalco G,Leva C,Blanzola C,Sala A

    更新日期：2006-04-04 00:00:00

  • Comparison of the Framingham Risk Score, SCORE and WHO/ISH cardiovascular risk prediction models in an Asian population.

    abstract：BACKGROUND:Cardiovascular risk-prediction models are used in clinical practice to identify and treat high-risk populations, and to communicate risk effectively. We assessed the validity and utility of four cardiovascular risk-prediction models in an Asian population of a middle-income country. METHODS:Data from a nati...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.ijcard.2014.07.066

    authors： Selvarajah S,Kaur G,Haniff J,Cheong KC,Hiong TG,van der Graaf Y,Bots ML

    更新日期：2014-09-01 00:00:00

  • Incidence and predictors of atrial fibrillation in a Chinese cohort of Brugada syndrome.

    abstract：BACKGROUND:Atrial electrophysiological abnormalities have previously been reported in Brugada syndrome. We investigated the incidence and electrocardiographic predictors of atrial fibrillation (AF) in a Chinese cohort of Brugada syndrome patients. METHODS:A retrospective study of Brugada syndrome patients admitted to ...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.ijcard.2020.05.007

    authors： Tse G,Lee S,Mok NS,Liu T,Chang D

    更新日期：2020-09-01 00:00:00

  • Relevance of simultaneous ST segment elevation and depression in an exercise treadmill test.

    abstract：:Simultaneous ST segment elevation and depression recorded during an exercise treadmill test and its correlation with coronary angiogram is a new finding that does not find a place in medical literature. We conclude that in the presence of simultaneous ST segment elevation and ST segment depression during exercise trea...

    journal_title：International journal of cardiology

    pub_type： 信件

    doi：10.1016/s0167-5273(01)00469-7

    authors： Prabhakar D,Vaidiyanathan D

    更新日期：2001-08-01 00:00:00

  • Differences in inflammatory and thrombotic markers between unstable angina and acute myocardial infarction.

    abstract：BACKGROUND:Unstable coronary syndromes are characterised by increased inflammatory process and endothelial activation. However, the underlying mechanisms of the acute coronary syndromes are still obscure. We evaluated the differences of inflammatory and thrombotic markers, at the acute phase of unstable angina (UA) and...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.ijcard.2006.03.011

    authors： Tousoulis D,Antoniades C,Bosinakou E,Kotsopoulou M,Tsoufis C,Marinou K,Charakida M,Stefanadi E,Vavuranakis M,Latsios G,Stefanadis C

    更新日期：2007-02-07 00:00:00

  • "Pulmonary valve replacement diminishes the presence of restrictive physiology and reduces atrial volumes": a prospective study in Tetralogy of Fallot patients.

    abstract：:Pulmonary valve replacement (PVR) reduces right ventricular (RV) volumes in the setting of long-term pulmonary regurgitation after Tetralogy of Fallot (ToF) repair; however, little is known of its effect on RV diastolic function. Right atrial volumes may reflect the burden of RV diastolic dysfunction. The objective of...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.ijcard.2014.09.009

    authors： Pijuan-Domenech A,Pineda V,Castro MA,Sureda-Barbosa C,Ribera A,Cruz LM,Ferreira-Gonzalez I,Dos-Subirà L,Subirana-Domènech T,Garcia-Dorado D,Casaldàliga-Ferrer J

    更新日期：2014-11-15 00:00:00

  • Angina after percutaneous coronary intervention: The need for precision medicine.

    abstract：:Persistence or recurrence of angina after successful percutaneous coronary intervention (PCI) represent an important clinical issue involving from one fifth to one third of patients undergoing myocardial revascularization at one-year follow-up. A systematic approach to this syndrome is strongly needed. Precision medic...

    journal_title：International journal of cardiology

    pub_type： 杂志文章,评审

    doi：10.1016/j.ijcard.2017.07.105

    authors： Niccoli G,Montone RA,Lanza GA,Crea F

    更新日期：2017-12-01 00:00:00

  • Cardiac MR1 and peripartum cardiomyopathy.

    abstract：:Cardiac MRI brings great benefits in the comprehension of the mechanism(s) involved in the genesis of peripartum cardiomyopathy (PPC). Cardiac MRI may also procure prognostic information. Because this is a rare affection, it seems necessary to systematically study PPC with this safe, non invasive and reliable tool. Cr...

    journal_title：International journal of cardiology

    pub_type： 评论,信件

    doi：10.1016/j.ijcard.2008.11.142

    authors： Leurent G

    更新日期：2010-07-23 00:00:00

  • Achieving contrast-free ultra-low radiation exposure without compromising safety and acute efficacy through evolving AF cryoballoon ablation procedure techniques.

    abstract：INTRODUCTION:In general, early experience with the first-generation cryoballoon introduced an increase in radiation exposure as compared to traditional radiofrequency ablations for atrial fibrillation (AF). However, through operator vigilance and the incorporation of various techniques and technologies, procedural radi...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.ijcard.2019.06.018

    authors： Reiss J,O'Connell H,Getman MK

    更新日期：2020-01-15 00:00:00

  • Clinical course of Chagas' heart disease: a comparison with dilated cardiomyopathy.

    abstract：:This investigation was carried out to compare the clinical course of patients with chronic Chagas' heart disease with that of patients with dilated cardiomyopathy. A total of 125 patients (75 chagasic and 50 nonchagasic) prospectively followed up at the Cardiomyopathy clinic of Santa Casa Hospital from January 1990 to...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/s0167-5273(97)00083-1

    authors： Bestetti RB,Muccillo G

    更新日期：1997-07-25 00:00:00

  • Magnetic resonance reveals long-term sequelae of apical ballooning syndrome.

    abstract：BACKGROUND:The presence of small areas of necrosis has been occasionally reported immediately following apical ballooning syndrome (ABS). However, their persistence at later stages and impact on long-term prognosis are currently unknown. METHODS:Twenty consecutive patients admitted for ABS between 2004 and 2007 were p...

    journal_title：International journal of cardiology

    pub_type： 临床试验,杂志文章

    doi：10.1016/j.ijcard.2008.08.023

    authors： Bellera MN,Ortiz JT,Caralt MT,Pérez-Rodon J,Mercader J,Fernández-Gómez C,Paré C,Heras M

    更新日期：2010-02-18 00:00:00

  • Feasibility limits of transradial primary percutaneous coronary intervention in acute myocardial infarction in the real life (TRAP-AMI).

    abstract：BACKGROUND:There is growing evidence that transradial (TRI) as compared to transfemoral (TFI) percutaneous coronary intervention (PCI) is associated with improved clinical outcome driven by less hemorrhagic complications, in particular in STEMI patients receiving aggressive antithrombotic treatment. Feasibility rate of...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.ijcard.2012.10.024

    authors： Gellen B,Lesault PF,Canouï-Poitrine F,Champagne S,Mouillet G,Pongas D,Le Thuaut A,Jakljevic T,Boudiche S,de la Vega M,Maalej A,Veugeois A,Dubois-Randé JL,Teiger E

    更新日期：2013-09-30 00:00:00

  • Left ventricular scar impact on left ventricular synchronization parameters and outcomes of cardiac resynchronization therapy.

    abstract：BACKGROUND:Left ventricular scar, including global scar and lateral wall, plays an important role in predicting response to cardiac resynchronization therapy (CRT). MATERIALS AND METHODS:Thirty patients underwent CRT implantation. Assessment of left ventricular (LV) dyssynchrony was done through Gated SPECT LV phase a...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.ijcard.2016.07.158

    authors： Ahmed W,Samy W,Tayeh O,Behairy N,Abd El Fattah A

    更新日期：2016-11-01 00:00:00

  • Characterisation of isoprenaline myotoxicity on slow-twitch skeletal versus cardiac muscle.

    abstract：BACKGROUND:Elevated catecholamines are known to be cardiotoxic, but their potential injurious effects on skeletal muscles are largely unknown. We have investigated whether isoprenaline induces in vivo myocyte necrosis in rat soleus muscle, and characterised the time-course, dose-response, spatial distribution and adren...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/s0167-5273(02)00369-8

    authors： Ng Y,Goldspink DF,Burniston JG,Clark WA,Colyer J,Tan LB

    更新日期：2002-12-01 00:00:00

  • Amine-enriched surface modification facilitates expansion, attachment, and maintenance of human cardiac-derived c-kit positive progenitor cells.

    abstract：BACKGROUND:Stem cells have a low expansion rate and are difficult to maintain in vitro. To overcome the problems of cardiovascular regeneration, we developed a novel method of stem cell cultivation in culture vessels with amine and carboxyl coatings. METHODS AND RESULTS:We isolated cardiac stem/progenitor cells from i...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.ijcard.2012.09.065

    authors： Choi SH,Jung SY,Yoo SM,Asahara T,Suh W,Kwon SM,Baek SH

    更新日期：2013-09-20 00:00:00