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Angina after percutaneous coronary intervention: The need for precision medicine.

Abstract：

:Persistence or recurrence of angina after successful percutaneous coronary intervention (PCI) represent an important clinical issue involving from one fifth to one third of patients undergoing myocardial revascularization at one-year follow-up. A systematic approach to this syndrome is strongly needed. Precision medicine is particularly important in addressing angina after successful PCI because of the multiple underlying causes. Restenosis or coronary atherosclerosis progression explain symptom recurrence after successful PCI in some patients, while functional causes, including vasomotor abnormalities of epicardial coronary arteries and/or coronary microvascular dysfunction, explain symptoms in the remaining patients. In this review, we summarize the mechanisms of persistent or recurrent angina after PCI, proposing a diagnostic algorithm and a systematic therapeutic approach.

journal_name

Int J Cardiol

journal_title

International journal of cardiology

authors

Niccoli G,Montone RA,Lanza GA,Crea F

doi

10.1016/j.ijcard.2017.07.105

subject

Has Abstract

pub_date

2017-12-01 00:00:00

pages

14-19

eissn

0167-5273

issn

1874-1754

pii

S0167-5273(17)33360-0

journal_volume

248

pub_type

杂志文章,评审

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