Abstract:
:Excellent medication adherence contributes to decreases in morbidity, mortality, and health care costs. Although researchers have tested many interventions to increase adherence, results are sometimes conflicting and often unclear. This systematic review applied meta-analytic procedures to integrate primary research that tested medication adherence interventions. Comprehensive searching completed in 2015 located 771 published and unpublished intervention studies with adherence behavior outcomes. Random-effects model analysis calculated standardized mean difference effect sizes. Meta-analytic moderator analyses examined the association between adherence effect sizes and sample, design, and intervention characteristics. Analyses were conducted in 2016. A standardized mean difference effect size of 0.290 comparing treatment and control groups was calculated. Moderator analyses revealed larger effect sizes for habit-based and behavioral-targeted (vs. cognitive-focused) interventions. The most effective interventions were delivered face-to-face, by pharmacists, and administered directly to patients. Effect sizes were smaller in studies with older and homeless participants. Risks of bias were common; effect sizes were significantly lower among studies with masked data collectors and intention-to-treat analyses. The largest effect sizes were reported by studies using medication electronic event monitoring and pill count medication adherence measures. Publication bias was present. This most comprehensive review to date documented that, although interventions can increase adherence, much room remains for improvement. Findings suggest health care providers should focus intervention content on behavioral strategies, especially habit-based interventions, more so than cognitive strategies designed to change knowledge and beliefs.
journal_name
Prev Medjournal_title
Preventive medicineauthors
Conn VS,Ruppar TMdoi
10.1016/j.ypmed.2017.03.008subject
Has Abstractpub_date
2017-06-01 00:00:00pages
269-276eissn
0091-7435issn
1096-0260pii
S0091-7435(17)30104-4journal_volume
99pub_type
杂志文章,meta分析,评审abstract::In 2014, an 8% tax on energy-dense nutrient-poor foods was implemented in Mexico with the aim of reducing its consumption. This paper estimated changes in household purchases of taxed food. We used the latest five waves of the nationally representative Mexican Income and Expenditure Survey (2008, 2010, 2012, 2014 and ...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/j.ypmed.2018.09.019
更新日期:2019-01-01 00:00:00
abstract::Sunburn is associated with an increased risk for skin cancer. Denmark has one of the highest incidences of melanoma in the world, although it is a relatively northern country. The objective of this study was to determine whether sunburn is associated with demographic factors and health behaviour among young Danes. Cro...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/j.ypmed.2018.08.009
更新日期:2019-01-01 00:00:00
abstract:OBJECTIVE:To investigate associations between employees' health locus of control (HLOC) and self-perceived health, health behaviors, and participation in health promotion programs (HPPs) and the mediating effect of self-perceived health and health behaviors on the relation between HLOC and participation. METHOD:Betwee...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/j.ypmed.2014.07.037
更新日期:2014-10-01 00:00:00
abstract::Foods for Health, a nutrition education and research program sponsored by the National Heart, Lung, and Blood Institute and Giant Food, Inc., was designed to demonstrate the feasibility of cardiovascular nutrition education at the point of purchase, specifically, in the supermarket. To evaluate the program's effective...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/0091-7435(86)90036-8
更新日期:1986-01-01 00:00:00
abstract:OBJECTIVE:The present study investigates the cross-sectional relationship between tobacco smoking and body fatness. METHODS:This cross-sectional study consisted of 469,543 men and women who participated in the European Prospective Investigation into Cancer and Nutrition (EPIC) study between 1992 and 2000 providing ant...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/j.ypmed.2009.08.009
更新日期:2009-11-01 00:00:00
abstract:OBJECTIVES:To address the question of whether serum cotinine is a better measure of cigarette smoking than self-reported behavior by examining the relation of biochemical, physical examination, and depression assessments to self-reported cigarette consumption and serum cotinine in a population-based sample. METHODS:Se...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1006/pmed.1995.1031
更新日期:1995-03-01 00:00:00
abstract:BACKGROUND:Medical illness has often been thought to provide smokers with motivation to quit smoking. However, the actual impact that illness and hospitalization has on smokers' interest in cessation is not clear. Further, little is known about the role that hospital staff play in encouraging cessation. METHODS:This a...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/0091-7435(92)90024-c
更新日期:1992-03-01 00:00:00
abstract:BACKGROUND:Analyses of secular trends in tobacco consumption can provide evidence of potential tobacco-disease relationships and have utility in terms of public health projections and policy. The purpose of this project was to provide a unique set of continuous apparent tobacco product consumption estimates for the Uni...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1006/pmed.2000.0780
更新日期:2001-01-01 00:00:00
abstract:BACKGROUND:Neonatal abstinence syndrome (NAS) occurs following prenatal opioid exposure. It is characterized by signs and symptoms indicating central nervous system hyperirritability and autonomic nervous system, gastrointestinal tract, and respiratory system dysfunction. OBJECTIVE:This article: (1) briefly reviews NA...
journal_title:Preventive medicine
pub_type: 历史文章,杂志文章
doi:10.1016/j.ypmed.2015.07.017
更新日期:2015-11-01 00:00:00
abstract:OBJECTIVE:There is evidence linking the built environment (BE) with physical activity (PA), but few studies have been conducted in Latin America (LA). State-of-the-art methods and protocols have been designed in and applied in high-income countries (HIC). In this paper, we identify key challenges and potential solution...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/j.ypmed.2014.10.014
更新日期:2014-12-01 00:00:00
abstract::Chronic kidney disease (CKD) affects 15% of the US general population, and this rate is projected to increase. A healthy lifestyle is important for individuals with CKD to reduce risk for CKD progression and adverse heath events. Adults with CKD also have high rates of psychological distress, which may be associated w...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/j.ypmed.2019.06.007
更新日期:2019-09-01 00:00:00
abstract:BACKGROUND:Inadequate opportunities for physical activity at school and overall low levels of activity contribute to the high prevalence of overweight and obesity in American-Indian children. METHODS:A school-based physical activity intervention was implemented which emphasized increasing the frequency and quality of ...
journal_title:Preventive medicine
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1016/j.ypmed.2003.08.005
更新日期:2003-12-01 00:00:00
abstract:BACKGROUND:While previous research has generally supported a relationship between hostility and health risk behaviors, the majority of this research has been conducted in predominately male, highly educated, Caucasian samples. The current study was designed to further examine the relationship between hostility and heal...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1006/pmed.2001.0921
更新日期:2001-12-01 00:00:00
abstract::Given the disease and cost burdens, Multiple Health Behavior Research represents the future of preventive medicine. Growing evidence in this special issue and beyond indicates that simultaneous and sequential interventions can be effective. The challenge for the future is to make such interventions more effective, cos...
journal_title:Preventive medicine
pub_type: 杂志文章,评审
doi:10.1016/j.ypmed.2008.01.015
更新日期:2008-03-01 00:00:00
abstract::Unhealthy behaviors and lifestyle choices are contributing to the obesity epidemic and associated morbidities. Among reproductive aged women, obesity adversely affects perinatal outcomes and longer term maternal and child health. Interventions utilizing strategies of behavior change have the potential to improve outco...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/j.ypmed.2017.07.023
更新日期:2017-11-01 00:00:00
abstract::Psychiatric hospitals are increasingly adopting smoke-free policies. Tobacco use is common among persons with mental illness, and nicotine withdrawal (NW), which includes symptoms of depression, anxiety, anger/irritability, and sleep disturbance, may confound psychiatric assessment and treatment in the inpatient setti...
journal_title:Preventive medicine
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ypmed.2016.01.026
更新日期:2016-11-01 00:00:00
abstract:BACKGROUND:Impact of physician diagnosis of overweight on successful weight loss in community-based patients is not known. We analyzed data from NHANES 1999-04 to assess if self-reported physician diagnosis of overweight was associated with attempted and successful weight loss in the preceding year. METHODS:We determi...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/j.ypmed.2010.04.013
更新日期:2010-07-01 00:00:00
abstract:BACKGROUND:Based on previous studies on the blocking effect of Chinese tea in the formation of N-nitroso compounds in rats and humans, experiments were carried out to study the effects of Chinese tea on the occurrence of esophageal tumors induced by N-nitrosomethylbenzylamine (NMBzA) in rats. METHODS:In the first expe...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/0091-7435(92)90046-k
更新日期:1992-05-01 00:00:00
abstract::A key element in most efforts to prevent disease and promote health is behavioral change to lower risk. One-to-one programs to help people change their behavior are seriously limited because of the difficulty people have in making behavioral changes and because one-to-one programs do little to modify those forces in t...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/0091-7435(86)90026-5
更新日期:1986-09-01 00:00:00
abstract:BACKGROUND:Considerable research has established that self-efficacy is a consistent correlate of physical activity. Additional factors, such as exercise-induced affect, social support, and value judgments, have also been identified as having the potential to influence adherence to activity. This study examined the util...
journal_title:Preventive medicine
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0091-7435(03)00089-6
更新日期:2003-08-01 00:00:00
abstract:BACKGROUND:The epidemiologic observation that physical activity reduces the risk for hypertension has only been made for white men who self-reported hypertension. This study examined physical activity and clinically determined incident hypertension in black and white men and women of the Atherosclerosis Risk in Communi...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1006/pmed.1998.0431
更新日期:1999-03-01 00:00:00
abstract::Childhood maltreatment is consistently associated with adult obesity, leading to calls for tailored weight interventions for people with maltreatment histories. However, it is possible that the maltreatment-obesity association is spurious and driven by unmeasured confounding, in which case such interventions would be ...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/j.ypmed.2018.02.016
更新日期:2018-05-01 00:00:00
abstract:OBJECTIVE:This paper assesses the potential benefits of increased walking and reduced obesity associated with taking public transit in terms of dollars of medical costs saved and disability avoided. METHODS:I conduct a new analysis of a nationally representative U.S. transportation survey to gauge the net increase in ...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/j.ypmed.2007.10.004
更新日期:2008-01-01 00:00:00
abstract:OBJECTIVE:We sought to assess the interaction of smoking and body mass index (BMI) on diabetes risk. METHODS:We analyzed data from a community-based prospective cohort of 41,836 women from Iowa who completed a baseline survey in 1986 and five subsequent surveys through 2004. The final analysis included 36,839 particip...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/j.ypmed.2008.10.008
更新日期:2009-01-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to investigate the association between self-efficacy, enjoyment, and volitional control with active commuting, as well as to analyze the impact of social support from parents, friends, and teachers with active commuting to school. METHODS:Participants in this cross-sectional study w...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/j.ypmed.2014.02.019
更新日期:2014-06-01 00:00:00
abstract:OBJECTIVE:The objective of the study is to evaluate cross-sectional and longitudinal changes in children's commuting to school in a representative sample of a Brazilian city. METHODS:Two school-based studies were carried out in 2002 (n=2936; 7-10 years old) and 2007 (n=1232; 7-15 years old) in Florianopolis, Brazil. C...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/j.ypmed.2012.06.023
更新日期:2012-09-01 00:00:00
abstract::The Human Genome Project has made it easier to genetically map and clone mutant genes which predispose to a great many human diseases. In addition to diseases inherited in a simple Mendelian fashion, there are many degenerative and infectious diseases, and sensitivities to environmental insults, in which the genetic m...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1006/pmed.1994.1094
更新日期:1994-09-01 00:00:00
abstract::The Patient Protection and Affordable Care Act (ACA) has increased insurance coverage among underserved individuals, but the effect of ACA on cancer diagnosis is currently debated, particularly in Medicaid non-expansion states. Therefore, we aimed to assess the effect of ACA implementation on stage at diagnosis among ...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/j.ypmed.2019.06.006
更新日期:2019-09-01 00:00:00
abstract::An international collaborative group examined the relation between asymptomatic hyperglycemia and coronary heart disease (CHD). After excluding clinically diagnosed diabetes and treated hypertensives, there were 48,912 men aged 35-64 in the study population. Post-load circulating glucose correlated with age, relative ...
journal_title:Preventive medicine
pub_type: 杂志文章
doi:10.1016/0091-7435(83)90173-1
更新日期:1983-01-01 00:00:00
abstract::In July 2018, Baltimore became the largest US city to prohibit restaurants from including sugar-sweetened beverages on kids' menus. In September 2018, California made history by becoming the first US state to require either water or milk as the default beverage with children's meals at all restaurants. Supporters of c...
journal_title:Preventive medicine
pub_type: 杂志文章,多中心研究,评审
doi:10.1016/j.ypmed.2019.03.031
更新日期:2019-06-01 00:00:00