Abstract:
PURPOSE:This cross-sectional study aims to evaluate saliva, serum levels of interleukin-21 (IL-21), IL-33, and prostaglandin E2 (PGE2) in patients with generalised chronic periodontitis or aggressive periodontitis. MATERIALS AND METHODS:Before initiation of any periodontal treatment, saliva and serum samples were collected and clinical periodontal measurements were recorded from 94 participants (25 aggressive periodontitis patients, 25 chronic periodontitis patients, 44 periodontally healthy individuals). IL-21, IL-33 and PGE2 levels in serum and saliva samples were determined by ELISA. Data were tested statistically using Kruskal-Wallis, Mann-Whitney U-, and Spearman-rho rank tests. RESULTS:Saliva IL-33 levels were statistically significantly higher in the chronic than the aggressive group (p < 0.05). Serum IL-33, saliva and serum IL-21 and PGE2 levels were similar in the two periodontitis groups. Saliva IL-33 levels correlated with age in the chronic periodontitis group (p < 0.05). Statistically significant positive correlations were found between serum, saliva PGE2 levels and plaque index (p < 0.05). IL-33 and IL-21 levels in serum samples positively correlated in the periodontitis groups (p < 0.05). CONCLUSION:IL-21 and PGE2 analysis did not exhibit discriminating data between generalised chronic and aggressive periodontitis, but the present findings support the role of these cytokines in periodontitis. Statistically significantly higher saliva IL-33 levels in the chronic periodontitis group warrant further research.
journal_name
Oral Health Prev Dentjournal_title
Oral health & preventive dentistryauthors
Gümüş P,Nizam N,Nalbantsoy A,Özçaka Ö,Buduneli Ndoi
10.3290/j.ohpd.a38740subject
Has Abstractpub_date
2017-01-01 00:00:00pages
385-390issue
4eissn
1602-1622issn
1757-9996pii
38740journal_volume
15pub_type
杂志文章abstract:PURPOSE:To examine the risks for being overweight (Ow) or obese (Ob) in subjects with elevated Periodontal Screening and Recording (PSRTM) Codes (> or =1) (with smoking as a modifier) in a population of dental school patients located within a region with a high incidence of Ow, Ob, diabetes mellitus (Db), and cardiovas...
journal_title:Oral health & preventive dentistry
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doi:
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journal_title:Oral health & preventive dentistry
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journal_title:Oral health & preventive dentistry
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doi:
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journal_title:Oral health & preventive dentistry
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doi:
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journal_title:Oral health & preventive dentistry
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journal_title:Oral health & preventive dentistry
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journal_title:Oral health & preventive dentistry
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journal_title:Oral health & preventive dentistry
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doi:
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journal_title:Oral health & preventive dentistry
pub_type: 杂志文章
doi:
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journal_title:Oral health & preventive dentistry
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doi:
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journal_title:Oral health & preventive dentistry
pub_type: 杂志文章
doi:
更新日期:2011-01-01 00:00:00
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journal_title:Oral health & preventive dentistry
pub_type: 杂志文章
doi:
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doi:10.3290/j.ohpd.a41811
更新日期:2019-01-01 00:00:00
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journal_title:Oral health & preventive dentistry
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journal_title:Oral health & preventive dentistry
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doi:
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journal_title:Oral health & preventive dentistry
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doi:
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journal_title:Oral health & preventive dentistry
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doi:
更新日期:2010-01-01 00:00:00
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journal_title:Oral health & preventive dentistry
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journal_title:Oral health & preventive dentistry
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doi:
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journal_title:Oral health & preventive dentistry
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doi:
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journal_title:Oral health & preventive dentistry
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