Mechanisms of differential axial blockade in epidural and subarachnoid anesthesia.

abstract：BACKGROUND:There is little information concerning the carbon dioxide-related effects on respiratory mechanics in anesthetized, paralyzed subjects; however, hypocapnia or hypercapnia is often permitted in patients with severe brain injury or acute respiratory distress syndrome. Therefore, the carbon dioxide dependence o...

journal_title：Anesthesiology

authors： D'Angelo E,Calderini IS,Tavola M

更新日期：2001-04-01 00:00:00

abstract：BACKGROUND:This study was conducted to compare the performance accuracy of the independent variables Bispectral Index (BIS), A-Line ARX index (AAI), and predicted propofol effect-site concentration (CePROP) to measure the dependent variables of loss of responses to different stimulation defined as loss of response to v...

journal_title：Anesthesiology

authors： Struys MM,Vereecke H,Moerman A,Jensen EW,Verhaeghen D,De Neve N,Dumortier FJ,Mortier EP

更新日期：2003-10-01 00:00:00

abstract：BACKGROUND:Chronic pain remains a significant challenge for modern health care as its pathologic mechanisms are largely unknown and preclinical animal models suffer from limitations in assessing this complex subjective experience. However, human brain neuroimaging techniques enable the assessment of functional and neur...

journal_title：Anesthesiology

authors： Harris RE,Napadow V,Huggins JP,Pauer L,Kim J,Hampson J,Sundgren PC,Foerster B,Petrou M,Schmidt-Wilcke T,Clauw DJ

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:Good postoperative recovery is increasingly recognized as an important outcome after surgery. The authors created a new Post-operative Quality Recovery Scale (PQRS) that tracks multiple domains of recovery from immediate to long-term time periods in patients of varying ages, languages, and cultures. METHODS...

journal_title：Anesthesiology

authors： Royse CF,Newman S,Chung F,Stygall J,McKay RE,Boldt J,Servin FS,Hurtado I,Hannallah R,Yu B,Wilkinson DJ

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND:Factors determining renal function at organ recovery in deceased kidney donors are not well established. METHODS:The authors studied the prevalence and risk factors associated with elevated prerecovery creatinine and calculated glomerular filtration rate in 458 deceased organ donors identified through the C...

journal_title：Anesthesiology

authors： Blasi-Ibanez A,Hirose R,Feiner J,Freise C,Stock PG,Roberts JP,Niemann CU

更新日期：2009-02-01 00:00:00

abstract：:The cerebral metabolic effects of a massive dose of thiopental (177 mg/kg) were investigated in seven dogs. The systemic circulation was supported with an extracorporeal circuit. At an infusion rate of 2 mg/kg/min, cerebral oxygen consumption (CMR(O(2))) decreased progressively until cerebral electrical silence was pr...

journal_title：Anesthesiology

authors： Michenfelder JD

更新日期：2002-10-01 00:00:00

abstract：:A constantly coupled bigeminal arrhythmia was induced in dogs anesthetized with thiopental-halothane by infusion of epinephrine (1 microgram.kg-1.min-1). The site of origin of the abnormal beat was localized to the interventricular septum by bipolar recordings from the left and right ventricular epicardium and two sit...

journal_title：Anesthesiology

authors： Smith ER,Dresel PE

更新日期：1982-08-01 00:00:00

abstract：BACKGROUND:Several beneficial effects of local anesthetics (LAs) were shown to be due to inhibition of G protein-coupled receptor signaling. Differences in exposure time might explain discrepancies in concentrations of LAs required to achieve these protective effects in vivo and in vitro (approximately 100-fold higher)...

journal_title：Anesthesiology

authors： Hollmann MW,Herroeder S,Kurz KS,Hoenemann CW,Struemper D,Hahnenkamp K,Durieux ME

更新日期：2004-04-01 00:00:00

abstract：BACKGROUND:Clinical concentrations of volatile anesthetics significantly influence contractile response to the sympathetic neurotransmitter norepinephrine although its precise mechanisms remain unclarified. In this study, we investigated its possible alterations in diabetes, as well as its underlying mechanisms. METHO...

journal_title：Anesthesiology

authors： Yoshino J,Akata T,Shirozu K,Izumi K,Hoka S

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND:Methylprednisolone, dexamethasone, and other glucocorticoids have been found effective against nausea and vomiting induced by chemotherapy and surgery. Although the specific 5-hydroxytriptamine3 (5-HT3) receptor antagonists such as ondansetron and ramosetron are used as antiemetics, reports show that the use...

journal_title：Anesthesiology

authors： Suzuki T,Sugimoto M,Koyama H,Mashimo T,Uchida I

更新日期：2004-09-01 00:00:00

abstract：BACKGROUND:Lamotrigine is a sodium channel blocker that inhibits the neuronal release of glutamate. Systemic administration of lamotrigine induces analgesia in short- and long-term models of hyperalgesia in rats. Considering the key role of N-methyl-D-aspartate receptors in the sensitization of dorsal horn neurons that...

journal_title：Anesthesiology

authors： Klamt JG

更新日期：1998-02-01 00:00:00

abstract：BACKGROUND:Although respiratory depression is the most well-known and dangerous side effect of opioids, no pharmacokinetic-pharmacodynamic model exists for its quantitative analysis. The development of such a model was the aim of this study. METHODS:After institutional approval approval and informed consent were obtai...

journal_title：Anesthesiology

authors： Bouillon T,Schmidt C,Garstka G,Heimbach D,Stafforst D,Schwilden H,Hoeft A

更新日期：1999-07-01 00:00:00

abstract：BACKGROUND:A combination of opioid and nonopioid analgesic drugs may improve the quality of postoperative analgesia as well as reduce opioid requirements and their associated side effects. Studies have shown synergism between gabapentin and morphine in animal and human experiments and in the treatment of incisional pai...

journal_title：Anesthesiology

authors： Turan A,Karamanlioğlu B,Memiş D,Hamamcioglu MK,Tükenmez B,Pamukçu Z,Kurt I

更新日期：2004-04-01 00:00:00

abstract：BACKGROUND:The diagnosis of an acute malignant hyperthermia reaction by clinical criteria can be difficult because of the nonspecific nature and variable incidence of many of the clinical signs and laboratory findings. Development of a standardized means for estimating the qualitative likelihood of malignant hypertherm...

journal_title：Anesthesiology

authors： Larach MG,Localio AR,Allen GC,Denborough MA,Ellis FR,Gronert GA,Kaplan RF,Muldoon SM,Nelson TE,Ording H

更新日期：1994-04-01 00:00:00

abstract：BACKGROUND:Awake tracheal intubation may evoke reflex bronchoconstriction in asthmatics. Whether this effect is altered by the choice of the local anesthetic used or by pretreatment with a beta2-adrenoceptor agonist is unknown. Therefore, we assessed the effect of awake fiberoptic intubation after lidocaine or dyclonin...

journal_title：Anesthesiology

authors： Groeben H,Schlicht M,Stieglitz S,Pavlakovic G,Peters J

更新日期：2002-12-01 00:00:00

abstract：:Cardiac output and myocardial blood flow decrease dramatically in a dose-dependent pattern in the young lamb during isoflurane anesthesia. This raises important questions about the ability of the young lamb to increase myocardial performance if oxygen delivery were compromised by a decrease in oxygen content during an...

journal_title：Anesthesiology

authors： Brett CM,Teitel DF,Heymann MA,Rudolph AM

更新日期：1989-11-01 00:00:00

abstract：BACKGROUND:The authors compare three techniques for insertion of the ProSeal laryngeal mask airway. METHODS:Two hundred forty healthy patients aged 18-80 yr were randomly allocated for ProSeal laryngeal mask airway insertion using the digital, introducer tool (IT), or gum elastic bougie (GEB)-guided techniques. The di...

journal_title：Anesthesiology

authors： Brimacombe J,Keller C,Judd DV

更新日期：2004-01-01 00:00:00

abstract：:To determine whether administration of nitrous oxide, 50% and 70%, could provide analgesia and anxiolysis during venous cannulation in pediatric patients, 165 ASA Physical Status 1 patients scheduled for elective surgery were studied. Children, 3 weeks to 18 yr of age, were randomly assigned either to receive nitrous ...

journal_title：Anesthesiology

authors： Henderson JM,Spence DG,Komocar LM,Bonn GE,Stenstrom RJ

更新日期：1990-02-01 00:00:00

abstract：BACKGROUND:Anecdotal reports suggest that the second trimester is the safest time to conduct a laparoscopic procedure on a pregnant patient, but this supposition has not been tested empirically. METHODS:Previously instrumented preterm sheep (total n = 8) at gestational day 90 (term, 145 days) were anesthetized and the...

journal_title：Anesthesiology

authors： Uemura K,McClaine RJ,de la Fuente SG,Manson RJ,Campbell KA,McClaine DJ,White WD,Stamler JS,Eubanks WS,Reynolds JD

更新日期：2004-12-01 00:00:00

abstract：:Medical records of 38 patients undergoing anesthesia and surgery for removal of an insulinoma were reviewed to determine 1) the safety of avoiding intraoperative glucose, 2) the appropriate frequency of plasma glucose analysis, and 3) the accuracy of using rebound hyperglycemia as an indication of tumor removal. Plasm...

journal_title：Anesthesiology

authors： Muir JJ,Endres SM,Offord K,van Heerden JA,Tinker JH

更新日期：1983-11-01 00:00:00

abstract：BACKGROUND:Combining a hypnotic and an analgesic to produce sedation, analgesia, and surgical immobility required for clinical anesthesia is more common than administration of a volatile anesthetic alone. The aim of this study was to apply response surface methods to characterize the interactions between remifentanil a...

journal_title：Anesthesiology

authors： Manyam SC,Gupta DK,Johnson KB,White JL,Pace NL,Westenskow DR,Egan TD

更新日期：2006-08-01 00:00:00

abstract：BACKGROUND:Adaptive support ventilation (ASV) allows the clinician to set a maximum plateau pressure (PP) and automatically adjusts tidal volume to keep PP below the set maximum. METHODS:ASV was compared to a fixed tidal volume of 6 ml/kg. ASV determined the respiratory rate and tidal volume based on its algorithms. M...

journal_title：Anesthesiology

authors： Sulemanji D,Marchese A,Garbarini P,Wysocki M,Kacmarek RM

更新日期：2009-10-01 00:00:00

abstract：:This study reports effects of halothane on tumor cells in vitro. Cells from the human colon cancer cell line HT-29 were exposed to various concentrations of halothane for 8-72 h. The effect of this exposure on this colon cancer cell line, with and without coincubation with the biologic response modifier gamma-interfer...

journal_title：Anesthesiology

authors： Rudnick S,Stevenson GW,Hall SC,Espinoza-Delgado I,Stevenson HC,Longo DL

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND:Perfluorocarbon (PFC) liquids are known to improve gas exchange and pulmonary function in various models of acute respiratory failure. Vaporization has been recently reported as a new method of delivering PFC to the lung. Our aim was to study the effect of PFC vapor on the ventilation/perfusion (VA/Q) matchi...

journal_title：Anesthesiology

authors： Hübler M,Souders JE,Shade ED,Polissar NL,Schimmel C,Hlastala MP

更新日期：2001-12-01 00:00:00

abstract：BACKGROUND:Ketamine has been associated with a unique spectrum of subjective "psychedelic" effects in patients emerging from anesthesia. This study quantified these effects of ketamine and related them to steady-state plasma concentrations. METHODS:Ketamine or saline was administered in a single-blinded crossover prot...

journal_title：Anesthesiology

authors： Bowdle TA,Radant AD,Cowley DS,Kharasch ED,Strassman RJ,Roy-Byrne PP

更新日期：1998-01-01 00:00:00

abstract：:The authors hypothesized that relaxation of airway smooth muscle by halothane lessens the dependence of airway resistance on lung volume, and that halothane alters the relationship between pulmonary resistance and lung volume by changing both the airway and tissue components of pulmonary resistance. The relationship a...

journal_title：Anesthesiology

authors： Joyner MJ,Warner DO,Rehder K

更新日期：1992-02-01 00:00:00

abstract：BACKGROUND:Ethical conduct in human research in anesthesia includes approval by an institutional review board (IRB) or ethics committee and informed consent. Evidence of these is sometimes lacking in journal publications. METHODS:The authors reviewed all publications involving human subjects in six leading anesthesia ...

journal_title：Anesthesiology

authors： Myles PS,Tan N

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND:The most sensitive diagnostic criterion of myasthenia gravis is a decrement in the muscular response to repetitive stimulation. The authors hypothesized that myasthenia gravis patients who show a train-of-four ratio (T4/T1) < 0.9 in the preanesthetic period will have increased sensitivity to nondepolarizing ...

journal_title：Anesthesiology

authors： Mann R,Blobner M,Jelen-Esselborn S,Busley R,Werner C

更新日期：2000-08-01 00:00:00

abstract：BACKGROUND:Chronic pain is associated with depression. In rodents, pain is often assessed by sensory hypersensitivity, which does not sufficiently measure affective responses. Low-dose ketamine has been used to treat both pain and depression, but it is not clear whether ketamine can relieve depression associated with c...

journal_title：Anesthesiology

authors： Wang J,Goffer Y,Xu D,Tukey DS,Shamir DB,Eberle SE,Zou AH,Blanck TJ,Ziff EB

更新日期：2011-10-01 00:00:00

abstract：:Methylnaltrexone Reverses Chronic Opioid-induced Constipation: A Randomized, Controlled Trial. By Yuan CS, Foss JF, O'Connor M, Osinski J, Karrison T, Moss J, Roizen MF. JAMA 2000; 130:142-8. Reprinted with permission. CONTEXT:Constipation is the most common chronic adverse effect of opioid pain medications in patien...

journal_title：Anesthesiology

authors： Moss J

更新日期：2019-01-01 00:00:00