Abstract：
BACKGROUND:To date, no randomized trial has directly addressed the question of whether intravenous (IV) tissue plasminogen activator (tPA) improves outcomes in IV tPA-eligible patients who will eventually undergo endovascular therapy (EVT), or whether a direct EVT strategy is equally effective. We performed a systematic review and meta-analysis to compare the efficacy and safety of direct EVT versus endovascular treatment with IV tPA (EVT+IV tPA) in adults with acute ischemic stroke. METHODS:We performed electronic searches of 6 databases from their inception to January 2017. Data were extracted and analyzed according to predefined clinical endpoints. RESULTS:Twelve comparative studies, comprising 1275 patients in the EVT-only arm and 1340 patients in the combined EVT+IV tPA arm, were included. The rates of good functional outcomes (modified Rankin Scale score ≤2) and 90-day mortality were not statistically significantly different between the EVT and EVT+IV tPA arms (44% vs. 48%; odds ratio [OR], 0.80; 95% confidence interval [CI], 0.64-1.002; P = 0.052 and 20.4% vs. 19.4%, OR 1.19; 95% CI, 0.83-1.71; P = 0.34, respectively). The rate of symptomatic intracranial hemorrhage also was not significantly different between the EVT and EVT+IV tPA arms (3.7% vs. 3.8%; OR, 0.98; 95% CI, 0.65-1.48; P = 0.91). There were no between-group differences in the rates of other complications. CONCLUSIONS:No significant differences between the 2 groups were found in terms of favorable functional outcome, mortality rate, or complications based on contemporary endovascular therapies.
journal_name
World Neurosurgjournal_title
World neurosurgeryauthors
Phan K,Dmytriw AA,Maingard J,Asadi H,Griessenauer CJ,Ng W,Kewagamang K,Mobbs RJ,Moore JM,Ogilvy CS,Thomas AJdoi
10.1016/j.wneu.2017.08.040subject
Has Abstractpub_date
2017-12-01 00:00:00pages
850-858.e2eissn
1878-8750issn
1878-8769pii
S1878-8750(17)31337-2journal_volume
108pub_type
杂志文章,meta分析,评审abstract：OBJECTIVE:The aim of this study is to reveal inhibitory effect of gamma knife irradiation on angiogenesis of meningiomas using rat corneal angiogenesis assay. METHODS:A total of 72 rats were divided into three preliminary groups. Each group, consisting of 24 rats, was implanted to World Health Organization (WHO) grade...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2013.06.021
更新日期：2013-11-01 00:00:00
abstract：BACKGROUND:Albeit rarely, different spinal pathologies may require surgical treatment during pregnancy. The management of such cases poses a series of challenges, starting with adequate body positioning. OBJECTIVE:To illustrate limits and indications of the different surgical positioning strategies for pregnant women ...
journal_title：World neurosurgery
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doi：10.1016/j.wneu.2020.02.044
更新日期：2020-06-01 00:00:00
abstract：BACKGROUND:Adenocarcinomas of müllerian origin are malignancies derived from tissues of the proximal third of the vagina, cervix, uterus, and fallopian tubes. These organs develop from the embryologic müllerian ducts. While reports of perineural spread of certain uterine and cervical carcinomas exist in the literature,...
journal_title：World neurosurgery
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doi：10.1016/j.wneu.2020.06.121
更新日期：2020-09-01 00:00:00
abstract：:From their origins as cardiovascular research tools, endovascular techniques have evolved to provide a minimally invasive means of diagnosis and therapy for individuals suffering from occlusive artery disease. The techniques were pioneered by William Harvey, whose work set the stage for all subsequent endovascular exp...
journal_title：World neurosurgery
pub_type： 历史文章,杂志文章,评审
doi：10.1016/j.wneu.2020.01.072
更新日期：2020-04-01 00:00:00
abstract：OBJECTIVE:This study sought to determine whether implantation of a newly designed nonfusion intracorporeal enhancement (NICE) system is an effective and safe way to treat osteoporotic vertebral compression fracture (OVCF). METHODS:Thirteen patients with OVCF (10 women, 3 men; mean age 69 years, T11-L4) were included. ...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2018.06.039
更新日期：2018-09-01 00:00:00
abstract：BACKGROUND:Syringomyelia due to intracranial hypotension is rarely described. As a consequence, intracranial hypotension is less recognized as a potential cause of syringomyelia or mistaken with Chiari type 1 malformation. The pathogeny is poorly understood, and we lack diagnostic and therapeutic strategies for this pa...
journal_title：World neurosurgery
pub_type： 杂志文章,评审
doi：10.1016/j.wneu.2016.04.062
更新日期：2016-07-01 00:00:00
abstract：OBJECTIVE:Sacroiliac joint pain can be disabling and recalcitrant to medical therapy. The innervation of this joint is poorly understood, especially its anterior aspect. Therefore, the present cadaveric study was performed to better elucidate this anatomy. METHODS:Twenty-four cadaveric sides underwent dissection of th...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2017.08.062
更新日期：2017-11-01 00:00:00
abstract：BACKGROUND:The mortality index, or the ratio of observed to expected mortality, is a reported quality metric that has been assumed to directly reflect patient care. However, documentation and coding that does not use knowledge of how a reported mortality index is derived could reflect poorly on a hospital or service li...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2019.10.022
更新日期：2020-01-01 00:00:00
abstract：BACKGROUND:For more than 2 decades, dural spinal cysts have been broadly classified as extradural and intradural. CASE DESCRIPTION:A 40-year-old woman presented with radicular thoracic pain. Intraoperative findings showed the cyst to be present within the dura itself. CONCLUSIONS:We suggest a revised classification o...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2015.11.051
更新日期：2016-04-01 00:00:00
abstract：OBJECTIVE:There is a lack of consensus regarding diagnosis, timing, and method of intervention for progressive enhancement on surveillance imaging after stereotactic radiosurgery (SRS) treatment of brain metastases. We sought to characterize current practices among neurosurgeons in identifying and treating infield tumo...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2020.04.046
更新日期：2020-07-01 00:00:00
abstract：BACKGROUND:Measurements of quantitative blood flow are crucial during brain vascular surgery. Indocyanine green video angiography (ICG-VAG) is an accepted method of blood flow visualization; however, quantitative techniques have not yet been established. Thus, the aim of this study was to further develop ICG analysis f...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2018.04.148
更新日期：2018-08-01 00:00:00
abstract：OBJECTIVES:To determine the criteria used by neurosurgery resident selection committees in different programs and to assess the process of selection. METHODS:A questionnaire based on the Electronic Residency Application Service (ERAS) guidelines was mailed to all 100 neurosurgery residency program directors in August ...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2013.08.019
更新日期：2014-03-01 00:00:00
abstract：BACKGROUND:The cause of postoperative heterotopic ossification (HO) after cervical disc replacement (CDR) is unclear. The aim of the present study was to investigate the incidence of HO, its clinical significance, and whether the degree of preoperative degeneration was associated with its occurrence. METHODS:Patients ...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2019.01.244
更新日期：2019-05-01 00:00:00
abstract：:We present an image of a patient's skull characterized by dark, irregular discoloration. This was discovered incidentally in a 66-year-old man who underwent craniotomy for resection of a glioblastoma. This image demonstrates cranial black bone disease. This is an abnormal bone pigmentation associated with long-term te...
journal_title：World neurosurgery
pub_type：
doi：10.1016/j.wneu.2019.11.114
更新日期：2020-02-01 00:00:00
abstract：BACKGROUND:Microscopic training is essential for development of neurosurgical skills. A range of models is reported in the literature for this purpose, including live animals, exvivo, and synthetic material. Among the factors involved in selection and development of a training station, cost is a decisive one. METHODS:...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2019.06.089
更新日期：2019-10-01 00:00:00
abstract：BACKGROUND:There is accumulating evidence of a potential beneficial effect of early surgical intervention after acute cervical spinal cord injury (SCI). However, around one third of all SCIs affect the thoracic spine. This cohort has not been extensively investigated, mainly because of less sensitive clinical readout m...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2019.11.015
更新日期：2020-02-01 00:00:00
abstract：BACKGROUND:Multiple biopsy samples are warranted for the histomolecular diagnosis of diffuse gliomas in the current molecular era, which possibly increases morbidity. OBJECTIVE:We assessed diagnostic yield, safety, and risk factors of postoperative morbidity after robot-assisted serial stereotactic biopsy sampling alo...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2020.12.127
更新日期：2021-01-04 00:00:00
abstract：BACKGROUND:Data on traumatic intraventricular hemorrhage (IVH) are currently limited, and therefore, the condition is not fully understood. The aim of this study was to determine the epidemiology of traumatic IVH and its effects on outcome in patients with blunt head trauma. METHODS AND MATERIALS:Using a nationwide tr...
journal_title：World neurosurgery
pub_type： 杂志文章,多中心研究
doi：10.1016/j.wneu.2018.02.183
更新日期：2018-06-01 00:00:00
abstract：BACKGROUND:Intraorbital and intracerebral cavernous malformation (CM) lesions are considered independent entities. Purely cerebral CMs have variable biology with recent evidence depicting inflammation as an important player and a risk factor for aggressiveness. We describe a case of concomitant left intraaxial and extr...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2019.07.145
更新日期：2019-11-01 00:00:00
abstract：BACKGROUND:Ionizing radiation is typically used during spine surgery for localization and guidance in instrumentation placement. Minimally invasive (MI) surgical procedures are increasingly popular and often require significantly more fluoroscopy, placing surgeons at risk for increased radiation exposure and radiation-...
journal_title：World neurosurgery
pub_type： 杂志文章,meta分析,评审
doi：10.1016/j.wneu.2014.07.041
更新日期：2014-12-01 00:00:00
abstract：:We studied a poorly known form of cerebrospinal fluid hypotension characterized by cervical myelopathy, a considerable growth in volume of the venous plexus of the cervical spine, and absence of headache. This form was first described by Miyazaki. We reported a case brought to our attention, reviewed the literature, a...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2015.04.030
更新日期：2015-09-01 00:00:00
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journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2016.12.019
更新日期：2017-03-01 00:00:00
abstract：BACKGROUND:The ETR that should be undertaken in patients with GBM remains controversial. This study aims to reiterate some independent predicting factors and to underscore the role and the ETR in increasing the survival of patients in the situation of developing countries, that is, without preoperative MRI or tractogra...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2009.06.001
更新日期：2010-02-01 00:00:00
abstract：OBJECTIVE:To retrospectively assess the surgical outcomes and complication rates following microvascular decompression (MVD) for trigeminal neuralgia, using a targeted, restricted retrosigmoid approach. METHODS:During the period 1994-2009, a total of 119 patients underwent MVD for trigeminal neuralgia. A retrospective...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2010.05.001
更新日期：2010-07-01 00:00:00
abstract：BACKGROUND:Xanthogranuloma is a chronic inflammatory mass characterized by cholesterol crystal deposition, which is rarely seen in the sellar region. The objective of this study is to identify the clinical features and cause of sellar xanthogranulomas. METHODS:We retrospectively analyzed manifestation, radiographic, a...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2019.06.021
更新日期：2019-10-01 00:00:00
abstract：BACKGROUND:After showing the success of mechanical thrombectomy (MT) in treating large-vessel occlusion stroke, the target population has been expanded to include patients with smaller and more distal vessels including the M2 segment of the middle cerebral artery. We compared the procedural and clinical outcomes of pat...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2019.04.175
更新日期：2019-08-01 00:00:00
abstract：BACKGROUND:Idiopathic spinal cord herniation is a rare condition that involves spinal cord herniation through a defect in the ventral dura. CASE DESCRIPTION:We present a case of a 61-year-old woman who initially presented in 2016 with an approximately 1-year history of burning right lower extremity pain and gait insta...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2019.05.219
更新日期：2019-09-01 00:00:00
abstract：INTRODUCTION:The aim of this study was to explore the predisposing factors for fracture nonunion after a lateral screw was combined with C2 pedicle/laminar screw for a type II odontoid fracture and hopefully provide references in decision making and surgical planning for spinal surgeons. METHODS:This is a retrospectiv...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2017.09.198
更新日期：2018-01-01 00:00:00
abstract：OBJECTIVE:Sphenoid wing meningiomas (SWMs) can be treated with complete surgical resection and the recently introduced endoscopic transorbital approach (ETOA) offers a minimally invasive alternative. In this study, the surgical outcome of ETOA and the extended mini-pterional approach (eMPTA) for SWMs with osseous invol...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2020.01.115
更新日期：2020-07-01 00:00:00
abstract：BACKGROUND:Traumatic brain injury (TBI) remains a life-threatening condition characterized by growing incidence worldwide, particularly in the aging population, in which the primary goal of treatment appears to be avoidance of chronic institutionalization. METHODS:To identify independent predictors of 30-day mortality...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2019.04.060
更新日期：2019-08-01 00:00:00
