Single and mixture toxicity of abamectin and difenoconazole to adult zebrafish (Danio rerio).

Abstract:

:Concerns have been raised in recent years on the potential risks related with pesticide mixtures that are likely to be present in agricultural edge-of-field waterbodies. Despite the high use of pesticides in tropical countries like Brazil, studies evaluating pesticide mixtures are especially scarce in the tropics. The insecticide abamectin and the fungicide difenoconazole are the main pesticides intensively used in Brazilian strawberry crop and are hence likely to occur simultaneously. The aim of the present study was therefore to evaluate the toxicity of abamectin, difenoconazole and their mixture to the tropical fish Danio rerio. Laboratory toxicity tests with the individual pesticides indicated 48 h-LC50 values of 59 μg L-1 for abamectin and 1.4 mg L-1 for difenoconazole. Mixtures of the two pesticides revealed a synergistic deviation of the independent action model. Implications of study findings for the aquatic risk assessment of pesticide mixtures, especially in tropical countries and indications for future research are discussed.

journal_name

Chemosphere

journal_title

Chemosphere

authors

Sanches ALM,Vieira BH,Reghini MV,Moreira RA,Freitas EC,Espíndola ELG,Daam MA

doi

10.1016/j.chemosphere.2017.09.027

subject

Has Abstract

pub_date

2017-12-01 00:00:00

pages

582-587

eissn

0045-6535

issn

1879-1298

pii

S0045-6535(17)31441-8

journal_volume

188

pub_type

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