Four-year clinical results of transcatheter self-expanding Medtronic CoreValve implantation in high-risk patients with severe aortic stenosis.

abstract：:The present study was undertaken to define the hormonal response to thyroid-releasing hormone (TRH) further in a large, healthy, ambulatory elderly group. Seventy-seven subjects over 60 years old, 30 males (MA) and 47 females (FA), and control subjects, 22 males (MC) and 42 females (FC) were studied. No difference in ...

journal_title：Age and ageing

authors： Kaiser FE

更新日期：1987-11-01 00:00:00

abstract：BACKGROUND:nasogastric tube (NGT) feeding is commonly used after stroke, but its effectiveness is limited by frequent dislodgement. OBJECTIVE:the objective of the study was to evaluate looped NGT feeding in acute stroke patients with dysphagia. METHODS:this was a randomised controlled trial of 104 patients with acute...

journal_title：Age and ageing

authors： Beavan J,Conroy SP,Harwood R,Gladman JR,Leonardi-Bee J,Sach T,Bowling T,Sunman W,Gaynor C

更新日期：2010-09-01 00:00:00

abstract：INTRODUCTION:Patients with Parkinson's disease (PD) are not routinely prescribed bone-protecting medication despite the fact that they are known to be at risk of falling. We investigated whether subjects with PD were more at risk of fractures than other patient groups in order to establish whether preventative measures...

journal_title：Age and ageing

authors： Genever RW,Downes TW,Medcalf P

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:The reason why elderly human hips tend to break in one of two anatomical regions is uncertain. Nutritional factors may affect the site of fracture. OBJECTIVE:To assess possible nutritional differences in patients with proximal femoral fractures. DESIGN:Prospective observational cohort study. SETTING:Unive...

journal_title：Age and ageing

authors： Maffulli N,Dougall TW,Brown MT,Golden MH

更新日期：1999-09-01 00:00:00

abstract：:Clinical observations suggest an age-associated decline in skin perfusion but there are few quantitative in vivo data on skin perfusion at various ages. We studied skin perfusion of the dorsum of the foot by determining the capillary blood flow velocity (CBFV) expressed in millivolts (mV), using laser Doppler flowmetr...

journal_title：Age and ageing

authors： Weiss M,Milman B,Rosen B,Eisenstein Z,Zimlichman R

更新日期：1992-07-01 00:00:00

abstract：:Sway has been measured by Wright's Ataxiameter in 151 frail elderly and five young subjects, and compared with various sensory modalities. There is a close relationship between increased sway and impaired vibration sense in the legs. No correlations emerged with proprioception but this may reflect the imprecision of t...

journal_title：Age and ageing

authors： Brocklehurst JC,Robertson D,James-Groom P

更新日期：1982-02-01 00:00:00

abstract：:Non-steroidal anti-inflammatory drugs are currently being investigated as agents to reduce the incidence and progression of Alzheimer's disease. Paradoxically they have also been reported to induce deleterious effects on the central nervous system, including aseptic meningitis and cognitive decline in the elderly. We ...

journal_title：Age and ageing

authors： Ashton D,Kim P,Griffiths N,Beran R

更新日期：2004-07-01 00:00:00

abstract：BACKGROUND:in a secondary analysis of a randomised controlled trial, we investigated whether 6 months of music-based multitask training had beneficial effects on cognitive functioning and mood in older adults. METHODS:134 community-dwellers aged ≥65 years at increased risk for falling were randomly assigned to either ...

journal_title：Age and ageing

authors： Hars M,Herrmann FR,Gold G,Rizzoli R,Trombetti A

更新日期：2014-03-01 00:00:00

abstract：Background:diabetes increases the risk of frailty that is a leading cause of disability and premature mortality in older people. Metabolic syndrome (MS) and insulin resistance (IR) are strong risk factors for diabetes and could, thus, lead to frailty. However, the association between MS or IR and frailty has barely bee...

journal_title：Age and ageing

authors： Pérez-Tasigchana RF,León-Muñoz LM,Lopez-Garcia E,Gutierrez-Fisac JL,Laclaustra M,Rodríguez-Artalejo F,Guallar-Castillón P

更新日期：2017-09-01 00:00:00

abstract：:Twenty digitalized elderly patients with chronic atrial fibrillation were randomized into a double-blind cross-over study. None was in overt heart failure and all were taking < 80 mg frusemide daily. They received xamoterol 200 mg b.d. for 2 months with their usual dose of digoxin for 1 month and placebo digoxin for t...

journal_title：Age and ageing

authors： Lawson-Matthew PJ,McLean KA,Dent M,Austin CA,Channer KS

更新日期：1995-07-01 00:00:00

abstract：BACKGROUND:vascular disease has been postulated to contribute to muscle dysfunction in old age. Previous studies examining the effects of cardiovascular drugs on muscle function have shown conflicting results. We therefore examined the association of angiotensin converting enzyme (ACE) inhibitor, thiazide and statin us...

journal_title：Age and ageing

authors： Witham MD,Syddall HE,Dennison E,Cooper C,McMurdo ME,Sayer AA

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:in older persons, anaemia is associated with a number of unfavourable outcomes. In approximately 30% of older persons with anaemia, the cause of the anaemia is unexplained. We assessed the clinical differences between subjects with explained and unexplained anaemia and investigated whether these subjects hav...

journal_title：Age and ageing

authors： Willems JM,den Elzen WP,Vlasveld LT,Westendorp RG,Gussekloo J,de Craen AJ,Blauw GJ

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:Therapists and nurses often use verbal instruction in the rehabilitation of mobility following stroke. This study aimed to determine whether performing a verbal cognitive task while walking adversely affected patients' balance and velocity. METHODS:There were two counterbalanced conditions: walking only and...

journal_title：Age and ageing

authors： Bowen A,Wenman R,Mickelborough J,Foster J,Hill E,Tallis R

更新日期：2001-07-01 00:00:00

abstract：BACKGROUND:Hypertension is a risk factor for both cardiovascular and cerebrovascular disease, with an increasing incidence with advancing patient age. Exercise interventions have the potential to reduce blood pressure in older adults, however, rates of exercise uptake and adherence are low, with 'lack of time' a common...

journal_title：Age and ageing

authors： Herrod PJJ,Lund JN,Phillips BE

更新日期：2020-10-17 00:00:00

abstract：METHOD:We investigated the association of total serum cholesterol concentrations and subsequent overall and coronary mortality in 304 patients aged > or =65 discharged from hospital after acute myocardial infarction. RESULTS:There was no association between total cholesterol concentrations and mortality due to either ...

journal_title：Age and ageing

authors： Bo M,Fiandra U,Fonte G,Bobbio M,Fabris F

更新日期：1999-05-01 00:00:00

abstract：BACKGROUND:a fall occurs when an individual experiences a loss of balance from which they are unable to recover. Assessment of balance recovery ability in older adults may therefore help to identify individuals at risk of falls. The purpose of this 12-month prospective study was to assess whether the ability to recover...

journal_title：Age and ageing

authors： Carty CP,Cronin NJ,Nicholson D,Lichtwark GA,Mills PM,Kerr G,Cresswell AG,Barrett RS

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:recent evidence suggests that the interaction between periods of sedentary and activity behaviour is important for health; providing distinctive information to assessment of activity alone. This study quantified activity and sedentary behaviour in older, community-dwelling adults. METHODS:fifty-six communit...

journal_title：Age and ageing

authors： Lord S,Chastin SF,McInnes L,Little L,Briggs P,Rochester L

更新日期：2011-03-01 00:00:00

abstract：:Myasthenia gravis is probably commoner than previously suspected, the annual incidence being nearer 9-10/million than earlier figures of 2-4/million. The current study found an annual incidence in Croyden of 9.1 per million (95% confidence limits 5.7-13.8 per million). Of the 22 patients (59%) seen in Croyden with new...

journal_title：Age and ageing

authors： Schon F,Drayson M,Thompson RA

更新日期：1996-01-01 00:00:00

abstract：OBJECTIVE:to review systematically the range of case definitions and methods used to measure falls in randomised controlled trials. DESIGN/METHODS:a Cochrane review of fall prevention interventions was used to identify fall definitions in published trials. Secondary searches of various databases were used to identify ...

journal_title：Age and ageing

authors： Hauer K,Lamb SE,Jorstad EC,Todd C,Becker C,PROFANE-Group.

更新日期：2006-01-01 00:00:00

abstract：:Serological tests for syphilis were performed on 659 elderly patients admitted to hospital medical and psychiatric departments. Positive tests were found in 23 patients (3.5% of the sample), 17 women and 6 men. Six were subsequently discovered to have been treated previously for syphilis, and one other had radiologica...

journal_title：Age and ageing

authors： Corrado OJ,Bowie PC,Bagnall WE,Waugh MA

更新日期：1989-11-01 00:00:00

abstract：:Spasticity is common after stroke and other neurological conditions and causes considerable limitations of movement, activities of daily living and participation. Interaction with other components of the upper motor neurone syndrome (UMNS) and the heterogeneity of patients' presentations together with limited tools fo...

journal_title：Age and ageing

authors： Graham LA

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:there is limited evidence of a protective effect of physical activity in preventing hip fractures among older people living in institutions and in those aged 80 or over. OBJECTIVE:to examine the relationship between physical activity and risk of hip fracture in frail older people. DESIGN:a case-control stu...

journal_title：Age and ageing

authors： Norton R,Galgali G,Campbell AJ,Reid IR,Robinson E,Butler M,Gray H

更新日期：2001-05-01 00:00:00

abstract：OBJECTIVES:To evaluate the influence of age on the day-night blood pressure rhythm and on the prevalence of vascular events in those whose systolic blood pressure (SBP) fell by <10% overnight (non-dippers). DESIGN:Cross-sectional observational cohort study. SETTING:Outpatient hypertension clinic. PARTICIPANTS:419 Hy...

journal_title：Age and ageing

authors： Di Iorio A,Marini E,Lupinetti M,Zito M,Abate G

更新日期：1999-01-01 00:00:00

abstract：INTRODUCTION:national reports have highlighted deficiencies in care provided to older surgical patients and suggested a role for innovative, collaborative, inter-specialty models of care. The extent of geriatrician-led perioperative services in the UK (excluding orthogeriatric services) has not previously been describe...

journal_title：Age and ageing

authors： Partridge JS,Collingridge G,Gordon AL,Martin FC,Harari D,Dhesi JK

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:Visuo-spatial neglect (VSN) after stroke is associated with a poor prognosis for rehabilitation. The co-existence of a visual field deficit (VFD) with VSN may be associated with impaired visuo-spatial functioning and thereby poor functional outcome. OBJECTIVE:To determine whether the presence of a VFD (i) e...

journal_title：Age and ageing

authors： Cassidy TP,Bruce DW,Lewis S,Gray CS

更新日期：1999-05-01 00:00:00

abstract：OBJECTIVES:this study investigated the prospective associations of accelerometer assessed daily steps with subsequent depressive symptoms in older adults. METHODS:a 2-year prospective study was performed in the community. A total of 285 older adults ≥65 years (mean age = 74.5) attended the baseline assessment in 2012....

journal_title：Age and ageing

authors： Hsueh MC,Stubbs B,Lai YJ,Sun CK,Chen LJ,Ku PW

更新日期：2020-09-25 00:00:00

abstract：BACKGROUND:fifteen percent of patients with Crohn's disease (CD) are elderly; they are less likely to have complications and more likely to have colonic disease. OBJECTIVE:to compare disease behaviour in patients with CD based on age at diagnosis. DESIGN:cross-sectional study. SETTING:tertiary referral centre. SUBJ...

journal_title：Age and ageing

authors： Quezada SM,Steinberger EK,Cross RK

更新日期：2013-01-01 00:00:00

abstract：Background:older patients admitted to hospitals are at risk for hospital-acquired morbidity related to immobility. The aim of this study was to implement and evaluate an evidence-based intervention targeting staff to promote early mobilisation in older patients admitted to general medical inpatient units. Methods:the ...

journal_title：Age and ageing

authors： Liu B,Moore JE,Almaawiy U,Chan WH,Khan S,Ewusie J,Hamid JS,Straus SE,MOVE ON Collaboration.

更新日期：2018-01-01 00:00:00

abstract：:A study of 414 elderly residents of sheltered accommodation in West Essex investigated the degree to which health, physical handicap and support from community care services affected dental needs and utilization of dental services. The study population had a mean age of 77 years, 77% lived alone, 17% were housebound a...

journal_title：Age and ageing

authors： Tobias B

更新日期：1988-03-01 00:00:00

abstract：:The frequency of snoring was studied in 46 patients with Alzheimer's disease (AD), 37 with multiinfarct dementia (MID), and in a random sample of 124 elderly community residents without known diseases affecting higher cortical functions. The demented patients were reported to snore twice as frequently as the control s...

journal_title：Age and ageing

authors： Erkinjuntti T,Partinen M,Sulkava R,Palomaki H,Tilvis R

更新日期：1987-09-01 00:00:00