Long-Term and Short-Term Antidepressant Use in General Practice: Data from a Large Cohort in the Netherlands.

Abstract:

BACKGROUND:Antidepressant use is highly prevalent. Research has mainly focused on efficacy during short periods of use for depression and anxiety. There is a relative paucity of data regarding the frequency of long-term use. METHODS:To determine the prevalence and possible increase of long-term use of antidepressants over recent years, we analyzed routine general practice care data in a large cohort of patients (n = 156,620) in and around Amsterdam, The Netherlands. Additionally, predictors of long-term use were studied. RESULTS:Prevalence of long-term use of antidepressants is substantial, and such use appears to be increasing: 30.3% of use was long-term over the period 1995-2005 compared to 43.7% for the period 2005-2015. Higher age, a registered diagnosis of anxiety or depression, and the use of SSRIs or SNRIs were associated with long-term use in multivariate analysis. In addition, specific antidepressants were differentially associated with long-term use. CONCLUSIONS:Long-term antidepressant use is substantial and appears to be on the rise. Awareness of this phenomenon should be increased, such use should be prevented when possible, and reasons for long-term use need to be examined.

journal_name

Psychother Psychosom

authors

Huijbregts KM,Hoogendoorn A,Slottje P,van Balkom AJLM,Batelaan NM

doi

10.1159/000480456

subject

Has Abstract

pub_date

2017-01-01 00:00:00

pages

362-369

issue

6

eissn

0033-3190

issn

1423-0348

pii

000480456

journal_volume

86

pub_type

杂志文章
  • National suicide rates 1961-2003: further analysis of nordic data for suicide, autopsies and ill-defined death rates.

    abstract:BACKGROUND:Concerns about the risk-benefit ratio of treatment with antidepressants in the light of recent evidence pointing to a risk of suicide induction during the course of treatment with antidepressants. These concerns have led to a series of recent studies exploring national rates of suicide and correlating these ...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 杂志文章

    doi:10.1159/000112884

    authors: Reseland S,Le Noury J,Aldred G,Healy D

    更新日期:2008-01-01 00:00:00

  • Evaluation of some criteria used to select patients for brief psychodynamic therapy.

    abstract:BACKGROUND AND OBJECTIVES:The effectiveness of brief psychotherapy is established, but criteria for the selection of patients remain elusive. This study examines the usefulness of some widely used criteria for the selection of patients for brief psychodynamic therapy (BPT). METHODS:A checklist of 39 criteria often use...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 杂志文章

    doi:10.1159/000012332

    authors: Sigal JJ,Paris J,Kardos M,Zimmerman G,Buonvino M

    更新日期:1999-01-01 00:00:00

  • Cognitive dysfunctions in bipolar disorder: evidence of neuropsychological disturbances.

    abstract::Although cognitive dysfunctions in psychosis have classically been associated with schizophrenia, there is clinical evidence that some bipolar patients show cognitive disturbances either during acute phases or in remission periods. The authors critically review the data on cognitive impairment in bipolar disorder. The...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 杂志文章,评审

    doi:10.1159/000012361

    authors: Martínez-Arán A,Vieta E,Colom F,Reinares M,Benabarre A,Gastó C,Salamero M

    更新日期:2000-01-01 00:00:00

  • Family psychiatry in psychosomatics: problems of adolescence.

    abstract::Adolescents are frequently entangled in a web of transitions during their developmental journey from child to adult. These modulations include physiological and psychological changes: individual, familial and social readjustments, and alterations in the evolving family group. Psychosomatic manifestations are often tar...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 杂志文章

    doi:10.1159/000287421

    authors: Rubinstein D

    更新日期:1980-01-01 00:00:00

  • Borderlines: problems of self and object separation.

    abstract::The borderline has deficiencies in the capacity to maintain stable self and object representations and in establishing 'emotional separateness' from others. In order to create and maintain a 'propitious treatment situation' and a 'therapeutic alliance' the therapist must work with unusual sensitivity and repetitivenes...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 杂志文章

    doi:10.1159/000287017

    authors: Leibovich MA

    更新日期:1976-01-01 00:00:00

  • Psychological prodromata of myocardial infarction and sudden death.

    abstract::In this prospective study a psychological test (the "Maastricht Questionnaire') was constructed which measures feelings of vital exhaustion and depression. It is shown that those subjects who have elevated scores on this test have more chance to get a new coronary event within a period of 10 months than those who have...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 杂志文章

    doi:10.1159/000287458

    authors: Appels A

    更新日期:1980-01-01 00:00:00

  • Psychosomatic studies of allergic disorders.

    abstract::It is generally conceded that allergic disorders occur in individuals who have a hereditary or congenital allergic constitution. Clinical symptoms of allergic disorders, however, often disappear due to changes of the individuals' life situations and/or their adaptive patterns. In a comparative study of allergic predis...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 杂志文章

    doi:10.1159/000287331

    authors: Agõ Y,Teshima H,Nagata S,Inoue S,Ikemi Y

    更新日期:1979-01-01 00:00:00

  • Subjective and objective assessments of medical comorbidity in chronic depression.

    abstract:BACKGROUND:While the extent of medical comorbidity in depressive illness is widely recognised, there have been few studies where objective and subjective assessment of comorbidity in chronic depression have been made. The aim of this study was to determine the extent and nature of medical comorbidity, in terms of both ...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 杂志文章

    doi:10.1159/000289144

    authors: Schrader GD

    更新日期:1997-01-01 00:00:00

  • Onset and recurrence of depression as predictors of cardiovascular prognosis in depressed acute coronary syndrome patients: a systematic review.

    abstract:BACKGROUND:Depression after acute coronary syndrome (ACS) is associated with worse cardiac outcomes. This systematic review evaluated whether depressed ACS patients are at differential risk depending on the recurrence and timing of onset of depressive episodes. METHODS:MEDLINE, EMBASE and PsycINFO were searched from i...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 杂志文章,评审

    doi:10.1159/000322633

    authors: Zuidersma M,Thombs BD,de Jonge P

    更新日期:2011-01-01 00:00:00

  • Short-term dynamic psychotherapy. I. The Oslo group's form to score outcome, the reliability testing of this form and observer characteristics.

    abstract::The aim of short-term dynamic psychotherapy is, through working with a central conflict and transference reactions, to obtain lasting changes based on cognitive and emotional understanding of the main dynamics of the central conflict, called insight. The aim of the present study was to construct a follow-up form that ...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 杂志文章

    doi:10.1159/000287850

    authors: Husby R,Dahl AA,Dahl CI,Heiberg AN,Olafsen OM,Weisaeth L

    更新日期:1985-01-01 00:00:00

  • Language acquisition in relation to cumulative posttraumatic stress disorder symptom load over time in a sample of re-settled refugees.

    abstract:OBJECTIVE:To study the effects of symptoms of posttraumatic stress disorder (PTSD), depression and dissociation as well as cumulative symptom load on language learning during the introduction phase in re-settled refugees. METHOD:Participants were re-settled refugees of Iraqi origin. They were assessed by means of a st...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 杂志文章

    doi:10.1159/000078849

    authors: Söndergaard HP,Theorell T

    更新日期:2004-09-01 00:00:00

  • Randomized controlled comparison of two cognitive behavioral therapies for obese children: mother versus mother-child cognitive behavioral therapy.

    abstract:BACKGROUND:Parent-child treatments have been shown to be superior to child-focused treatments of childhood obesity. Yet until now, the comparative effectiveness of parent-only and parent-child approaches has been little studied. METHOD:Fifty-six obese children and their families were randomly assigned to a 16-session ...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 杂志文章,随机对照试验

    doi:10.1159/000129659

    authors: Munsch S,Roth B,Michael T,Meyer AH,Biedert E,Roth S,Speck V,Zumsteg U,Isler E,Margraf J

    更新日期:2008-01-01 00:00:00

  • Patterns of self-definition of asthma patients and normal persons in the Freiburg Personality Inventory.

    abstract::The concept of the specificity of psychosomatic diseases (Alexander) is being differentiated at the time. In order to clarify some aspects of this problem, we want to investigate whether types of self-rating of normal persons differ from those of patients with bronchial asthma. In a second step we shall examine whethe...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 杂志文章

    doi:10.1159/000288407

    authors: Deter HC,Schepank H

    更新日期:1991-01-01 00:00:00

  • Psychosomatic medicine: some past and current concepts.

    abstract::Recognition of the body-mind dilemma goes back to antiquity. Growth in medical knowledge has produced an ever increasing emphasis on physiological deviations and somatic pathology--which too often is not accompanied by sufficient attention to the total patients. Psychosomatics is now the term often used by those who b...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 历史文章,杂志文章

    doi:10.1159/000287311

    authors: Dorfman W

    更新日期:1979-01-01 00:00:00

  • Discomfort or disability in patients with chronic pain syndrome.

    abstract::In the present study of 253 patients with chronic pain syndrome we have made a multidimensional approach. All patients have been included in the study independent of coexisting states of anxiety or depression. We included criteria for diagnosis, duration, generability and intensity of pain, anxiety and depression, psy...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 临床试验,杂志文章

    doi:10.1159/000288032

    authors: Poulsen DL,Hansen HJ,Langemark M,Olesen J,Bech P

    更新日期:1987-01-01 00:00:00

  • Short psychotherapeutic interventions (four sessions).

    abstract::This paper points out: (1) The fundamental importance, during the patient's first visit, of a shift of the objective involvement on the therapist's person, when a significant real object fails. (2) An initial interpretation, based on understanding this mechanism, is mutational in that it transfers the mourning for rel...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 杂志文章

    doi:10.1159/000288131

    authors: Gillieron E

    更新日期:1989-01-01 00:00:00

  • Personality traits in patients with acute low-back pain. A comparison with chronic low-back pain patients.

    abstract::This study investigates the possibilities to identify, within a group of acute low-back pain patients, individuals with psychogenic etiology to pain. 26 acute back pain patients and 25 healthy control subjects were tested with the Minnesota Multiphasic Personality Inventory Hysteria: (Hs), Hypochondria (Hy), Depressio...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 杂志文章

    doi:10.1159/000288546

    authors: Sivik TM

    更新日期:1991-01-01 00:00:00

  • Inpatient versus day clinic treatment for bulimia nervosa: a randomized trial.

    abstract:BACKGROUND:In bulimia nervosa, more intense treatments are recommended if outpatient treatment fails. This is the first randomized controlled trial comparing the options of inpatient versus day clinic treatment. METHOD:Patients with severe bulimia nervosa were randomly assigned to inpatient or day clinic treatment of ...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 杂志文章,随机对照试验

    doi:10.1159/000206869

    authors: Zeeck A,Weber S,Sandholz A,Wetzler-Burmeister E,Wirsching M,Hartmann A

    更新日期:2009-01-01 00:00:00

  • Type A behaviour, attention, and the report of subjective arousal.

    abstract::Previous research has indicated a tendency among type A individuals to report less subjective arousal than type B individuals. Differences in attentional style between type A and type B individuals have been suggested to account for this tendency. The present paper describes a study which employed adult male subjects ...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 杂志文章

    doi:10.1159/000288021

    authors: Roldan FH

    更新日期:1987-01-01 00:00:00

  • Alexithymia and psychopathology in patients with psychiatric and functional gastrointestinal disorders.

    abstract:BACKGROUND:Alexithymia and psychopathology may influence the way individuals experience psychological distress and somatic symptoms. This study evaluated patients referred to psychiatric and gastroenterologic outpatient settings in order to investigate the levels of alexithymia and psychopathology, and the possible rol...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 杂志文章

    doi:10.1159/000075539

    authors: Porcelli P,Affatati V,Bellomo A,De Carne M,Todarello O,Taylor GJ

    更新日期:2004-03-01 00:00:00

  • Should treatment distinguish anxiogenic from anxiolytic obsessive-compulsive ruminations? Results of a pilot controlled study and of a clinical audit.

    abstract::In a small pilot controlled study over 8 weeks, 12 obsessive-compulsive ruminators listened for 2 h daily to their own audiotaped voice either (1) describing their anxiogenic thoughts (exposure) but omitting anxiolytic thoughts (mental/cognitive rituals), or (2) reading neutral prose or poetry. Taking all patients, bo...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1159/000288883

    authors: Lovell K,Marks IM,Noshirvani H,O'Sullivan G

    更新日期:1994-01-01 00:00:00

  • Assessment of patients by DSM-III-R and DSM-IV in a Japanese psychosomatic clinic.

    abstract:BACKGROUND:The aim of this study was to investigate the clinical features of psychosomatic disorders in Japan. METHODS:A total of 1,432 outpatients (515 males and 917 females; 9-95 years of age, mean age 36) attending a psychosomatic clinic for the first time were assessed by the DSM-III-R or DSM-IV semistructured int...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 杂志文章

    doi:10.1159/000012258

    authors: Nakao M,Nomura S,Yamanaka G,Kumano H,Kuboki T

    更新日期:1998-01-01 00:00:00

  • Elevated blood levels of dehydroepiandrosterone sulphate vary with symptom load in posttraumatic stress disorder: findings from a longitudinal study of refugees in Sweden.

    abstract:BACKGROUND:The present study is part of a longitudinal study of recently resettled refugees with the aim of learning which factors in their daily life influence health as measured by self-report and stress-responsive hormones. METHODS:In a group of recently resettled refugees with a high incidence of posttraumatic str...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 杂志文章

    doi:10.1159/000064806

    authors: Söndergaard HP,Hansson LO,Theorell T

    更新日期:2002-09-01 00:00:00

  • The influence of social factors on the response to stress.

    abstract::The studies described in this paper provide evidence for the importance of social factors in determining the response of the hypothalamic-pituitary-adrenal (H-P-A) system to stress. The presence of familiar social partners can reduce or eliminate the cortisol response to either loss of a significant social relationshi...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 杂志文章

    doi:10.1159/000288677

    authors: Levine S

    更新日期:1993-01-01 00:00:00

  • Relations between pain, anxiety, mood and muscle tension in chronic pain patients. A correlation study.

    abstract::The relationship between psychological variables, particularly depressed mood and anxiety, and pain has received a good deal of attention. In this study, 16 chronic pain patients rated their mood, anxiety level, pain, muscle tension, and reclining time daily over a period of about 6 weeks. Correlations were calculated...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 杂志文章

    doi:10.1159/000287864

    authors: Linton SJ,Götestam KG

    更新日期:1985-01-01 00:00:00

  • Psychoanalytic-Interactional Therapy versus Psychodynamic Therapy by Experts for Personality Disorders: A Randomized Controlled Efficacy-Effectiveness Study in Cluster B Personality Disorders.

    abstract:BACKGROUND:With regard to cluster B personality disorders, most psychotherapeutic treatments focus on borderline personality disorder. Evidence-based treatments for patients with other cluster B personality disorders are not yet available. Psychoanalytic-interactional therapy (PIT) represents a transdiagnostic treatmen...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 杂志文章,随机对照试验

    doi:10.1159/000441731

    authors: Leichsenring F,Masuhr O,Jaeger U,Rabung S,Dally A,Dümpelmann M,Fricke-Neef C,Steinert C,Streeck U

    更新日期:2016-01-01 00:00:00

  • Psychiatric morbidity in renal transplantation.

    abstract::51 patients on chronic dialysis, awaiting transplantation, were assessed using a standardised psychiatric interview, together with measures of anxiety, depression, locus of control and social adjustment. 33% of the patients warranted a psychiatric diagnosis. During the study period, 30 patients received a transplanted...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 杂志文章

    doi:10.1159/000288297

    authors: Sensky T

    更新日期:1989-01-01 00:00:00

  • Effects of interventions involving the family in the treatment of adult patients with chronic physical diseases: a meta-analysis.

    abstract:BACKGROUND:Families can have considerable influence on the health of a patient with a chronic physical disease, and attempts have been made to optimise treatment by involving family members. This meta-analysis aimed to systematically assess the effects of family-oriented interventions on adults with chronic physical di...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 杂志文章,meta分析

    doi:10.1159/000286958

    authors: Hartmann M,Bäzner E,Wild B,Eisler I,Herzog W

    更新日期:2010-01-01 00:00:00

  • Psychophysiological responses of borderline hypertensives in two experimental situations.

    abstract::Given the contradictory reports concerning psychophysiological reactivity of hypertensives this issue was reexamined. In contrast to the large majority of studies, the hypertensive sample should not be made up of patients in medical care and the control group should be comparable in all relevant aspects other than blo...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 杂志文章

    doi:10.1159/000288936

    authors: Köhler T,Scherbaum N,Ritz T

    更新日期:1995-01-01 00:00:00

  • Traumatic war experiences affect outcome in a case of Tourette's syndrome.

    abstract:BACKGROUND:Stress has been associated with the course of Tourette's syndrome (TS). METHODS:The case report presented aims to emphasize the effect a severe traumatic experience has on the expression of TS. RESULTS:Following an intense traumatic experience, combat-related, a relatively mild case of TS became intractabl...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 杂志文章

    doi:10.1159/000289057

    authors: Witzum E,Bar-On R,Dolberg OT,Kotler M

    更新日期:1996-03-01 00:00:00