Long-Term and Short-Term Antidepressant Use in General Practice: Data from a Large Cohort in the Netherlands.

Abstract:

BACKGROUND:Antidepressant use is highly prevalent. Research has mainly focused on efficacy during short periods of use for depression and anxiety. There is a relative paucity of data regarding the frequency of long-term use. METHODS:To determine the prevalence and possible increase of long-term use of antidepressants over recent years, we analyzed routine general practice care data in a large cohort of patients (n = 156,620) in and around Amsterdam, The Netherlands. Additionally, predictors of long-term use were studied. RESULTS:Prevalence of long-term use of antidepressants is substantial, and such use appears to be increasing: 30.3% of use was long-term over the period 1995-2005 compared to 43.7% for the period 2005-2015. Higher age, a registered diagnosis of anxiety or depression, and the use of SSRIs or SNRIs were associated with long-term use in multivariate analysis. In addition, specific antidepressants were differentially associated with long-term use. CONCLUSIONS:Long-term antidepressant use is substantial and appears to be on the rise. Awareness of this phenomenon should be increased, such use should be prevented when possible, and reasons for long-term use need to be examined.

journal_name

Psychother Psychosom

authors

Huijbregts KM,Hoogendoorn A,Slottje P,van Balkom AJLM,Batelaan NM

doi

10.1159/000480456

subject

Has Abstract

pub_date

2017-01-01 00:00:00

pages

362-369

issue

6

eissn

0033-3190

issn

1423-0348

pii

000480456

journal_volume

86

pub_type

杂志文章
  • Psychosomatic aspects in self-help groups made up of medical patients. Presented on the example of the ostomy group.

    abstract::We present the psychosomatic aspects in self-help groups containing medical patients on the examples of the ostomy group. Following the demonstration of the psychodynamic group processes, the patients' psychological characteristics are described as well as the aims of this type of self-help group. The specific ostomy ...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 杂志文章

    doi:10.1159/000287321

    authors: Freyberger H

    更新日期:1979-01-01 00:00:00

  • A study of somatopsychic vulnerability in encopretic children.

    abstract::In this article the results of a study to determine the degree of somatopsychic vulnerability in children with encopresis are discussed. A checklist was constructed for the registration of somatic and functional data relevant to encopresis. Twenty-five children with encopresis were compared with a control group. The e...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 杂志文章

    doi:10.1159/000286894

    authors: Wolters WH,Wauters EA

    更新日期:1975-01-01 00:00:00

  • Short psychotherapeutic interventions (four sessions).

    abstract::This paper points out: (1) The fundamental importance, during the patient's first visit, of a shift of the objective involvement on the therapist's person, when a significant real object fails. (2) An initial interpretation, based on understanding this mechanism, is mutational in that it transfers the mourning for rel...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 杂志文章

    doi:10.1159/000288131

    authors: Gillieron E

    更新日期:1989-01-01 00:00:00

  • Training general practitioners in the treatment of functional somatic symptoms: effects on patient health in a cluster-randomised controlled trial (the Functional Illness in Primary Care study).

    abstract:BACKGROUND:Patients with medically unexplained or functional somatic symptoms (FSS) are prevalent in primary care. In this pragmatic cluster-randomised controlled trial we aimed to test the effect of a training programme (The Extended Reattribution and Management model) for general practitioners (GPs) in the treatment ...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 杂志文章,随机对照试验

    doi:10.1159/000313691

    authors: Toft T,Rosendal M,Ørnbøl E,Olesen F,Frostholm L,Fink P

    更新日期:2010-06-01 00:00:00

  • Sending the patient home.

    abstract::Some patients become grossly disorganized during a hospital stay for medical illness. In the midst of a confusing medical picture, the unpredictable behavior of such patients causes great consternation among the medical or surgical staff. Families also become particularly anxious; their concern about the medical probl...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 杂志文章

    doi:10.1159/000287284

    authors: Nadelson T

    更新日期:1978-01-01 00:00:00

  • Psychosomatic studies of allergic disorders.

    abstract::It is generally conceded that allergic disorders occur in individuals who have a hereditary or congenital allergic constitution. Clinical symptoms of allergic disorders, however, often disappear due to changes of the individuals' life situations and/or their adaptive patterns. In a comparative study of allergic predis...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 杂志文章

    doi:10.1159/000287331

    authors: Agõ Y,Teshima H,Nagata S,Inoue S,Ikemi Y

    更新日期:1979-01-01 00:00:00

  • Short-term psychotherapy and hypnosis.

    abstract::Phobic patients have been shown to be, on average, more hypnotizable than others. The essence of the phobic experience is not unlike that of the event of hypnosis, and the phobic experience might be a spontaneously occurring panic-filled trance-like or dissociative experience. This dissociation is viewed as a maladapt...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 杂志文章

    doi:10.1159/000287509

    authors: Frankel FH

    更新日期:1981-01-01 00:00:00

  • Subjective and objective assessments of medical comorbidity in chronic depression.

    abstract:BACKGROUND:While the extent of medical comorbidity in depressive illness is widely recognised, there have been few studies where objective and subjective assessment of comorbidity in chronic depression have been made. The aim of this study was to determine the extent and nature of medical comorbidity, in terms of both ...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 杂志文章

    doi:10.1159/000289144

    authors: Schrader GD

    更新日期:1997-01-01 00:00:00

  • Hypnosis with specific relation to biofeedback and behavior therapy. Theoretical and clinical considerations.

    abstract::Hypnosis as an intrapsychological and interpersonal experience is used as an integrative and amplifying procedure in relation to biofeedback mechanism and behavior therapy. The hypnotic capacity for linking cognitive to affective reactions within a feedback loop of sensory and motor imagery is presented as a dynamic a...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 杂志文章

    doi:10.1159/000287343

    authors: Kline MV

    更新日期:1979-01-01 00:00:00

  • Managing noncompliance in the 'difficult' medical patient: the contributions of insight. A case report.

    abstract::Psychodynamics can interfere with medical compliance, especially in psychologically vulnerable patients. A case is presented of a cancer patient who developed a powerful transference reaction to her oncologist, jeopardizing her treatment for cancer. Strategies for integrating techniques of insight-oriented psychothera...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 杂志文章

    doi:10.1159/000288393

    authors: Wyszynski AA

    更新日期:1990-01-01 00:00:00

  • Prognostic factors in outpatient psychotherapy of bulimia.

    abstract::Little is known about prognostic factors in the treatment of bulimic patients. In the context of an ongoing study we looked at 1-year symptomatic outcome of 37 outpatients fulfilling DSM-III-R criteria for bulimia nervosa in relation to a variety of measures at first assessment. These included multiple measures of dep...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 杂志文章

    doi:10.1159/000288530

    authors: Herzog T,Hartmann A,Sandholz A,Stammer H

    更新日期:1991-01-01 00:00:00

  • Father kills mother: post-traumatic stress disorder in the children.

    abstract::Results of a study of over 100 children whose father killed their mother have been summarized and principles for practice have been formulated. All children orphaned by the death of one parent at the other's hands should be seen as soon as possible in a child psychiatry department and assessed. An immediate crisis int...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 杂志文章

    doi:10.1159/000288592

    authors: Black D,Harris-Hendriks J,Kaplan T

    更新日期:1992-01-01 00:00:00

  • The social phobia psychotherapy research network. The first multicenter randomized controlled trial of psychotherapy for social phobia: rationale, methods and patient characteristics.

    abstract::This paper presents the Social Phobia Psychotherapy Research Network. The research program encompasses a coordinated group of studies adopting a standard protocol and an agreed-on set of standardized measures for the assessment and treatment of social phobia (SP). In the central project (study A), a multicenter random...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 杂志文章

    doi:10.1159/000162299

    authors: Leichsenring F,Hoyer J,Beutel M,Herpertz S,Hiller W,Irle E,Joraschky P,Konig HH,de Liz TM,Nolting B,Pohlmann K,Salzer S,Schauenburg H,Stangier U,Strauss B,Subic-Wrana C,Vormfelde S,Weniger G,Willutzki U,Wiltink J,

    更新日期:2009-01-01 00:00:00

  • What prevents professional drivers from following physicians' cardiologic advice?

    abstract:BACKGROUND:There is a scarcity of published studies of the effects of cardiac counselling among professional drivers (PD). Aims of the study were: (1) to examine explanatory variables for two classical 'driver' risk factors - body mass index (BMI), and smoking - and to analyse the interrelations among smoking cessation...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 杂志文章

    doi:10.1159/000012285

    authors: Emdad R,Belkic K,Theorell T,Cizinsky S

    更新日期:1998-07-01 00:00:00

  • Multidisciplinary teams in consultation-liaison psychiatry: the Yale model.

    abstract::The consultation-liaison service at Yale features integrated teams of psychiatrists, social workers, and clinical nurse specialists working together in both consultation and outpatient settings. The model is based on the tenets that (1) comprehensive evaluation of patients is essential for effective treatment; (2) rol...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 杂志文章

    doi:10.1159/000288036

    authors: Leigh H

    更新日期:1987-01-01 00:00:00

  • Role of the therapist in biofeedback training.

    abstract::The therapist in biofeedback training plays the role of a teacher or coach. This role, derived from learning theory and practiced in the classroom and playing field, imposes special constraints upon the psychotherapeutic situation. The therapist must be capable of physiological manipulation in self before attempting t...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 杂志文章

    doi:10.1159/000287297

    authors: Amar PB

    更新日期:1978-01-01 00:00:00

  • Biofeedback and behavioral approaches in Japan.

    abstract::A number of studies and case histories involving the use of biofeedback and behavioral approaches throughout Japan have been selected from Japanese journals and summarized. Areas of biofeedback research covered are experimental, clinical and psychological/educational. The behavioral approaches mentioned have been limi...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 杂志文章

    doi:10.1159/000287547

    authors: Ishikawa H,Robinson A

    更新日期:1981-01-01 00:00:00

  • Psychophysiological responses of borderline hypertensives in two experimental situations.

    abstract::Given the contradictory reports concerning psychophysiological reactivity of hypertensives this issue was reexamined. In contrast to the large majority of studies, the hypertensive sample should not be made up of patients in medical care and the control group should be comparable in all relevant aspects other than blo...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 杂志文章

    doi:10.1159/000288936

    authors: Köhler T,Scherbaum N,Ritz T

    更新日期:1995-01-01 00:00:00

  • Internet-based psychodynamic versus cognitive behavioral guided self-help for generalized anxiety disorder: a randomized controlled trial.

    abstract:BACKGROUND:Guided Internet-based cognitive behavior therapy (ICBT) has been tested in many trials and found to be effective in the treatment of anxiety and mood disorders. Generalized anxiety disorder (GAD) has also been treated with ICBT, but there are no controlled trials on guided Internet-based psychodynamic treatm...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 杂志文章,随机对照试验

    doi:10.1159/000339371

    authors: Andersson G,Paxling B,Roch-Norlund P,Östman G,Norgren A,Almlöv J,Georén L,Breitholtz E,Dahlin M,Cuijpers P,Carlbring P,Silverberg F

    更新日期:2012-01-01 00:00:00

  • Supportive psychotherapy.

    abstract::By way of introduction the concepts 'helpful-supportive' (in analytical psychotherapy) and 'exclusive-supportive' psychotherapy are defined. Then the indications and the patients' characteristics (marked ego weakness, dependency wishes) concerning exclusive-supportive psychotherapy in psychosomatic medicine are outlin...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 杂志文章,评审

    doi:10.1159/000288881

    authors: Freyberger H,Freyberger HJ

    更新日期:1994-01-01 00:00:00

  • Anxiety and hope during the course of three different medical illnesses: a longitudinal study.

    abstract:BACKGROUND:Somatic illness and its consequences evoke strong emotions of various kinds. They may affect the course of illness and the treatment results through their physiological components. The purpose of the study was to explore emotional reactions to different kinds of illnesses and changes of these emotions over t...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 杂志文章

    doi:10.1159/000012348

    authors: Heszen-Niejodek I,Gottschalk LA,Januszek M

    更新日期:1999-01-01 00:00:00

  • Relations between pain, anxiety, mood and muscle tension in chronic pain patients. A correlation study.

    abstract::The relationship between psychological variables, particularly depressed mood and anxiety, and pain has received a good deal of attention. In this study, 16 chronic pain patients rated their mood, anxiety level, pain, muscle tension, and reclining time daily over a period of about 6 weeks. Correlations were calculated...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 杂志文章

    doi:10.1159/000287864

    authors: Linton SJ,Götestam KG

    更新日期:1985-01-01 00:00:00

  • Studies of endocrine and affective functions in complex flight manoeuvres.

    abstract::Endocrine and metabolic changes, as well as affective functions, were studied in eight healthy volunteers anticipating and executing a prearranged sequence of aerobatic flight. Control measurements were made at complete physical and mental rest. The following were determined: anxiety and hostility levels, blood glucos...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 杂志文章

    doi:10.1159/000286916

    authors: Pinter EJ,Peterfy G,Cleghorn JM

    更新日期:1975-01-01 00:00:00

  • Alexithymia and psychopathology in patients with psychiatric and functional gastrointestinal disorders.

    abstract:BACKGROUND:Alexithymia and psychopathology may influence the way individuals experience psychological distress and somatic symptoms. This study evaluated patients referred to psychiatric and gastroenterologic outpatient settings in order to investigate the levels of alexithymia and psychopathology, and the possible rol...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 杂志文章

    doi:10.1159/000075539

    authors: Porcelli P,Affatati V,Bellomo A,De Carne M,Todarello O,Taylor GJ

    更新日期:2004-03-01 00:00:00

  • Self-exposure treatment of recurrent nightmares: waiting-list-controlled trial and 4-year follow-up.

    abstract:BACKGROUND:In open and randomized controlled trials self-exposure therapy reduced the frequency of nightmares but follow-up ceased at 7 months post-entry. METHOD:Ten adults who attended an outpatient clinic and had DSM-IV nightmare disorder were put on a 3-month waiting-list. After 3 months they were given a self-expo...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 杂志文章,随机对照试验

    doi:10.1159/000095445

    authors: Grandi S,Fabbri S,Panattoni N,Gonnella E,Marks I

    更新日期:2006-01-01 00:00:00

  • Illness behavior, emotional stress and psychosocial factors among asymptomatic HIV-infected patients.

    abstract:BACKGROUND:Over the last years the way in which patients with chronic physical illness respond to their illness (illness behavior) has been explored by several studies. This study sought to examine characteristics of illness behavior and to investigate the association between illness behavior and psychosocial and clini...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 临床试验,杂志文章

    doi:10.1159/000012308

    authors: Grassi L,Righi R,Makoui S,Sighinolfi L,Ferri S,Ghinelli F

    更新日期:1999-01-01 00:00:00

  • Validation of the Derogatis Stress Profile using laboratory and real world data.

    abstract::The Derogatis Stress Profile (DSP) is unique among the numerous measures of 'stress' in that it incorporates the interactional model of Lazarus and Folkman in a multidimensional structure. Derogatis has studied the psychometric properties of the DSP but its validity has not been demonstrated in the 'real world' nor ha...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 杂志文章

    doi:10.1159/000288555

    authors: Dobkin PL,Pihl RO,Breault C

    更新日期:1991-01-01 00:00:00

  • Psychotic Depression: Diagnosis, Differential Diagnosis, and Treatment.

    abstract::Psychotic depression was initially considered to be at one end of a continuum of severity of major depression. Subsequent experience demonstrated that psychosis is an independent trait that may accompany mood disorders of varying severity. While much has been learned about the impact of severe mood congruent delusions...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 杂志文章,评审

    doi:10.1159/000511348

    authors: Dubovsky SL,Ghosh BM,Serotte JC,Cranwell V

    更新日期:2020-11-09 00:00:00

  • Coping with fear of long-term complications in diabetes mellitus: a model clinical program.

    abstract::Preliminary results are reported on the efficacy of a behaviorally oriented group therapy (n = 17) intended to improve coping with fear of long-term complications in patients with diabetes mellitus. Treatment consisted of exposure in imagination, relaxation training and analysis of dysfunctional health beliefs. Pre-, ...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 杂志文章

    doi:10.1159/000289009

    authors: Zettler A,Duran G,Waadt S,Herschbach P,Strian F

    更新日期:1995-01-01 00:00:00

  • The prevalence and differential diagnosis of subclinical depressive syndromes in inpatients 60 years and older.

    abstract:BACKGROUND:Depressive syndromes that do not comply with the diagnostic criteria for specific depressive disorders are designated as 'subclinical' or 'subsyndromal' depressive syndromes. Using our own data from a clinical study, this paper outlines the significance of subclinical depressive syndromes and demonstrates th...

    journal_title:Psychotherapy and psychosomatics

    pub_type: 杂志文章

    doi:10.1159/000012404

    authors: Schneider G,Kruse A,Nehen HG,Senf W,Heuft G

    更新日期:2000-09-01 00:00:00