Abstract：
:All definitions of bronchopulmonary dysplasia (BPD) have limitations and a new definition for the purpose of clinical research, benchmarking, and prognostic prediction is needed. Different inhaled and systemic drugs are currently used to prevent or treat BPD. Despite some positive effects on BPD, more information about the effects of inhaled corticosteroids is required to assess overall efficacy and associated risks. One needs to balance the risks of neurodevelopmental impairment owing to systemic corticosteroids against those of BPD itself. Future studies should, therefore, focus on infants with a very high risk of developing BPD and include pharmacokinetics and long-term developmental outcomes.
journal_name
Pediatr Clin North Amjournal_title
Pediatric clinics of North Americaauthors
Bassler D,van den Anker Jdoi
10.1016/j.pcl.2017.08.012subject
Has Abstractpub_date
2017-12-01 00:00:00pages
1355-1367issue
6eissn
0031-3955issn
1557-8240pii
S0031-3955(17)30115-3journal_volume
64pub_type
杂志文章,评审abstract：:The benefits and possible detriment of resistance training have been noted extensively in the literature. Although the benefits of resistance training are well known, many professionals fail to heed scientific advice or follow appropriate recommendations for resistance training in adolescents. When developing a resist...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.pcl.2010.02.009
更新日期：2010-06-01 00:00:00
abstract：:Neural tube defects represent some of the most common and serious of the congenital malformations. Although elevation of alpha-fetoprotein in amniotic fluid is not diagnostic, it does indicate an abnormality of the fetus in a very high proportion of cases. A normal level, however, does not exclude the possibility of a...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章
doi：10.1016/s0031-3955(16)33607-0
更新日期：1978-08-01 00:00:00
abstract：:Childhood lead poisoning is still an enormous public health issue in the United States, affecting thousands of children and their families. New evidence suggests that even very low blood lead levels, less than 10 microg/dL, can be associated with neurologic injury. This article discusses characteristics of children at...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.pcl.2007.01.008
更新日期：2007-04-01 00:00:00
abstract：:Traumatic injuries represent the most important threat to the health of children in the United States and are the leading cause of death after the first year of life. More than 20,000 children and young adults will die this year as a result of injury. For every child that dies, another 40 will require hospitalization ...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章
doi：10.1016/s0031-3955(05)70049-3
更新日期：1998-08-01 00:00:00
abstract：:Over the past decade, much progress has been made in understanding the risk factors and timing of perinatal HIV transmission. Even more impressive have been the successful clinical trials with antiretrovirals, such as ZDV, ZDV-3TC, and nevirapine, that demonstrated significant reductions in the risk for infant infecti...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s0031-3955(05)70193-0
更新日期：2000-02-01 00:00:00
abstract：:The American Heart Association/American Academy of Pediatrics Neonatal Resuscitation Program provides standards for management of newborn infants in birthing areas. Certification and subsequent evaluation of birthing area personnel at perinatal network hospitals should result in better stabilization of infants prior t...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章
doi：10.1016/s0031-3955(16)38519-4
更新日期：1993-04-01 00:00:00
abstract：:The U.S. Preventive Services Task Force, convened and staffed by the U.S. Public Health Service, is evaluating the scientific basis of various preventive services to develop age- and sex-specific recommendations concerning their appropriate use in clinical settings. Over the course of the next few years, the Task Forc...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章
doi：10.1016/s0031-3955(16)36086-2
更新日期：1986-08-01 00:00:00
abstract：:ADHD is a syndrome that can be treated effectively, safely, and economically with stimulant medications. There is no equal alternative to these agents in short-term treatment of ADHD symptoms. However, many families seek alternatives to stimulants and other drug treatments for a variety of reasons. Alternative approac...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s0031-3955(05)70167-x
更新日期：1999-10-01 00:00:00
abstract：:This article addresses the current and desired future state of interprofessional practice in pediatric hospital medicine. It focuses on identifying optimal team composition and work patterns, describing the value of parent involvement on both the patient's care team and on operational teams, describing the need for in...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.pcl.2019.03.003
更新日期：2019-08-01 00:00:00
abstract：:Pediatric patients with ostomies are a challenge to health care providers. An ostomy is not without problems. Knowledge of surgical techniques and a commitment to the care and management of the stoma and appliances are needed to prevent and manage complications. Ongoing patient education is paramount for compliance an...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s0031-3955(05)70097-3
更新日期：1998-12-01 00:00:00
abstract：:In spite of a large volume of data regarding the in vitro activity of single and combined antimicrobial activity, the clinical relevance of these studies is unclear. Few comparative trials of combined and single antibiotic therapy of human infection have been performed. Synergistic combination therapy has been shown t...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s0031-3955(16)34325-5
更新日期：1983-02-01 00:00:00
abstract：:The causes of macroscopic and microscopic hematuria overlap; both are often caused by urinary tract infections or urethral/bladder irritation. Coexistent hypertension and proteinuria should prompt investigation for glomerular disease. The most common glomerulonephritis in children is postinfectious glomerulonephritis....
journal_title：Pediatric clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.pcl.2018.08.003
更新日期：2019-02-01 00:00:00
abstract：:Varicella zoster virus (VZV), herpes simplex virus (HSV) and cytomegalovirus (CMV) are all members of the Herpesviridae family.Humans are the only source of infection for these double stranded DNA viruses. Infants may acquire these infections in utero, peripartum, or postnatally, resulting in a variety of clinical syn...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.pcl.2004.03.005
更新日期：2004-08-01 00:00:00
abstract：:Approximately 10 per cent of all school-aged children have some type of learning disorder. These students are usually labeled mentally retarded, learning disabled, or emotionally disturbed/behavior disordered. The authors discuss the commonly used definitions of these disorders, the prognosis in school for children wi...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章
doi：10.1016/s0031-3955(16)34571-0
更新日期：1984-04-01 00:00:00
abstract：:Table 4 briefly summarizes the relative advantages and disadvantages of skin tests versus in vitro tests for detecting allergen-specific IgE. The skin test remains unexcelled as a sensitive and cost efficient test for specific IgE. The high degree of skin test sensitivity is very important when a patient must be evalu...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s0031-3955(16)36544-0
更新日期：1988-10-01 00:00:00
abstract：:Renal arteriography remains the only study to identify and define correctly both location and extent of renal artery stenosis. Because other studies do not adequately identify all children who have renal artery disease, it is reasonable to perform renal arteriography in those children with severe hypertension who do n...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s0031-3955(16)38485-1
更新日期：1993-02-01 00:00:00
abstract：:This article focuses on recent developments that have defined the autoimmune nature of this entity and its genetic basis, especially the crucial roles of aspartic acid at position 57 of the DQ beta chain and arginine at position 52 of the DQ alpha chain of the HLA complex on chromosome 6 in conferring susceptibility; ...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s0031-3955(05)70476-4
更新日期：1997-04-01 00:00:00
abstract：:Pediatric fractures are seen commonly in emergency departments. Pediatricians are usually the first physicians to assess injured children. Pediatricians should be comfortable in evaluating the fracture and interpreting radiographs prior to consulting an orthopedist. An understanding of the differences between pediatri...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s0031-3955(05)70447-8
更新日期：1996-10-01 00:00:00
abstract：:The unique biologic characteristics and behaviors of children make them vulnerable to environmental toxicants. Physicians and other health professionals are challenged in addressing pediatric environmental health care needs in part because of deficient knowledge and skills in pediatric environmental health. This defic...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章
doi：10.1016/j.pcl.2006.11.001
更新日期：2007-02-01 00:00:00
abstract：:Cerebral palsy describes a wide spectrum of motor problems caused by a nonprogressive lesion of the developing brain. It is variably associated with a variety of other developmental and medical problems that present challenges to parents and care providers alike. This article provides an overview of etiology and diagn...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.pcl.2008.07.003
更新日期：2008-10-01 00:00:00
abstract：:Injury is the most important threat to the health of children in the United States and the leading cause of death after the first year of life. Injuries must be viewed as diseases that can be prevented by using principles of epidemiology, engineering, biomechanics, and health education. Effective preventative strategi...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章
doi：10.1016/s0031-3955(16)38666-7
更新日期：1993-12-01 00:00:00
abstract：:Although pediatric hospital medicine (PHM) is in its adolescence, it is already having a major impact on patient care, quality, safety, and education. Pediatric hospitalists have been front-and-center in the safety and quality movement, driving change as clinicians, applying evidence-based medicine to standardize prac...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.pcl.2019.03.013
更新日期：2019-08-01 00:00:00
abstract：:Gastrointestinal motility disorders in the pediatric population are common and can range from benign processes to more serious disorders. Performing and interpreting motility evaluations in children present unique challenges. There are primary motility disorders but abnormal motility may be secondary due to other dise...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.pcl.2017.01.011
更新日期：2017-06-01 00:00:00
abstract：:Herpes simplex encephalitis (HSE) is an uncommon disease, yet 25 to 30 per cent of cases involve children. The initial clinical findings are nonspecific (fever, altered mental status), but most cases evolve to demonstrate focal neurologic signs and symptoms. The CSF is abnormal in over 90 per cent of cases. The EEG, C...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s0031-3955(16)36466-5
更新日期：1988-06-01 00:00:00
abstract：:Respiratory system involvement in cystic fibrosis is the leading cause of morbidity and mortality. Defects in the cystic fibrosis transmembrane regulator (CFTR) gene throughout the sinopulmonary tract result in recurrent infections with a variety of organisms including Pseudomonas aeruginosa, methicillin-resistant Sta...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.pcl.2016.04.007
更新日期：2016-08-01 00:00:00
abstract：:The opportunity to mobilize linkages between quality improvement (QI) and research is at an early stage. This article describes some of the opportunities for and challenges of integrating QI and more traditional forms of clinical research to achieve broad improvements in medical care. The authors suggest that such int...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章
doi：10.1016/j.pcl.2009.05.008
更新日期：2009-08-01 00:00:00
abstract：:As adolescents develop their sexual identities they are at risk for acquiring sexually transmitted diseases, unwanted pregnancies, and cervical dysplasia. As physical growth and development progress during adolescence, the risk of developing dysmenoorhea or adverse effects from exposure to diethylstilbestrol increase....
journal_title：Pediatric clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s0031-3955(16)33825-1
更新日期：1980-02-01 00:00:00
abstract：:This article describes important aspects of health-care quality, quality improvement (QI), patient safety (PS), and approaches to research on QI/PS efforts. Common terminology to facilitate an understanding of QI and PS research is reviewed. Models for understanding system and process performance are discussed. Introd...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.pcl.2015.12.006
更新日期：2016-04-01 00:00:00
abstract：:Breast lesions, including mastalgia; benign proliferative changes; and benign masses, including fibroadenomas, are common in adolescents and young adult women. Breast cancer is rare in women less than 20 years old and uncommon in women less than 30 years old. Discrete masses in women less than 30 years old that do not...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s0031-3955(05)70140-1
更新日期：1999-06-01 00:00:00
abstract：:Diuretics are used in various conditions with fluid overload. Their efficacy in the management of congestive heart failure is well documented. In contrast, the indication of diuretics in chronic lung disease and central nervous system disorders of the newborn have not been clearly established. Substantial pharmacologi...
journal_title：Pediatric clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s0031-3955(16)36766-9
更新日期：1989-10-01 00:00:00
