Abstract:
:A fixed-dose combination tablet of the hepatitis C virus (HCV) NS5A inhibitor elbasvir and the HCV NS3/4A protease inhibitor grazoprevir (elbasvir/grazoprevir; Zepatier™) is under development by Merck. Oral elbasvir/grazoprevir 50/100 mg once daily has been approved in the USA for the treatment of adults with chronic HCV genotype 1 or 4 infection. This article summarizes the milestones in the development of elbasvir/grazoprevir leading to this first global approval for chronic HCV genotype 1 or 4 infection.
journal_name
Drugsjournal_title
Drugsauthors
Keating GMdoi
10.1007/s40265-016-0558-3subject
Has Abstractpub_date
2016-04-01 00:00:00pages
617-24issue
5eissn
0012-6667issn
1179-1950pii
10.1007/s40265-016-0558-3journal_volume
76pub_type
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