Abstract:
:We compared the susceptibility to viral infection of splenocytes, isolated from young versus old CBA mice, and evaluated the antiviral actions of lactoferrin in splenocytes infected with Encephalomyocarditis virus (EMCV). Recombinant mouse lactoferrin (rmLF) and bovine lactoferrin (bLF) were used. There were no differences in the susceptibility to EMCV infection in the studied age categories. Both types of lactoferrins were protective in young and old mice. The study confirmed the undisturbed viral resistance in old mice and the protective actions of lactoferrin in viral infection. The antiviral action of the homologous mouse lactoferrin was demonstrated for the first time.
journal_name
Pol J Microbioljournal_title
Polish journal of microbiologyauthors
Zaczyńska E,Artym J,Kocięba M,Burster T,Kruzel M,Paprocka M,Zimecki Mdoi
10.5604/17331331.1235002subject
Has Abstractpub_date
2017-03-30 00:00:00pages
131-134issue
1eissn
1733-1331issn
2544-4646pii
01.3001.0010.4397journal_volume
66pub_type
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