Abstract：
OBJECTIVE:To investigate the association between single nucleotide polymorphisms or haplotypes of the COL4A1 gene and the risk of intracerebral hemorrhage (ICH). METHODS:We conducted a case-control study that included 181 patients from the Chinese Han population with hypertensive ICH and 197 hypertension patients without ICH. Genomic DNA was extracted by DNA extraction kit, and the 6 single nucleotide polymorphism genotypes of the COL4A1 gene were detected with a MassARRAY Analyzer. Unphased 3.1.4 and SPSS 19.0 were used to analyze the association between alleles, genotypes, and haplotypes of the COL4A1 gene and the risk of ICH. RESULTS:Compared with the control group, patients in the ICH group were significantly younger. There were no differences in gender, diabetes, hyperlipidemia, current smoking, and alcohol consumption between the 2 groups. Our association analysis showed that the rs3742207 A, rs11069830 A, and rs679505 A alleles were association factors of the risks of ICH; rs11069830 AA, rs544012 AC, and rs679505 AA genotypes were association factors of the risk of ICH; AA haplotype (rs3742207-rs11069830) was an association factor of the risk of ICH. After adjusting age and gender by multivariate logistic regression, the rs544012 AC and rs679505 AA genotypes were independently associated with the risk of ICH. CONCLUSIONS:Our study showed that the rs544012 AC and rs679505 AA genotypes were independently associated with the risk of ICH in the Chinese Han population and that the AA haplotype (rs3742207-rs11069830) in the COL4A1 gene may be related to the risk of ICH in the Chinese Han population; these conclusions need further confirmation in future studies with larger samples.
journal_name
World Neurosurgjournal_title
World neurosurgeryauthors
Lin S,Xia C,He S,Yang J,Li H,Zheng J,Liu M,You Cdoi
10.1016/j.wneu.2018.01.072subject
Has Abstractpub_date
2018-04-01 00:00:00pages
e527-e533eissn
1878-8750issn
1878-8769pii
S1878-8750(18)30115-3journal_volume
112pub_type
杂志文章abstract：:The radiological signs of intracranial dural arteriovenous fistulas (ICDAVFs) are heterogenous. While it is commonly accepted that hyper intense T2 wedge magnetic resonance imaging of the brainstem and cervical cord mainly concern gliomas, it is so far uncommon and probably unknown that ICDAVFs can imitate similar rad...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2018.02.161
更新日期：2018-05-01 00:00:00
abstract：BACKGROUND:The use of a 3-throw knot for anastomosis by microvascular neurosurgeons is the usual standard. There is an inherent belief that the third throw adds extra security to the knot; however, the third throw can make the knot heavy and unbalanced and can exert undue extra pressure on the opposing walls of the sma...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2020.12.078
更新日期：2020-12-22 00:00:00
abstract：BACKGROUND:Flow diversion (FD) has emerged as an effective treatment modality for aneurysms of the posterior communicating artery (PCOM). Whether or not a fetal posterior circulation (FPC) affects PCOM aneurysm occlusion rates after FD remains undetermined. METHODS:We performed a retrospective cohort study in which tr...
journal_title：World neurosurgery
pub_type： 杂志文章,多中心研究
doi：10.1016/j.wneu.2019.04.112
更新日期：2019-07-01 00:00:00
abstract：BACKGROUND/OBJECTIVE:The safety and efficacy of endovascular treatment of previously clipped aneurysms have not been well-established. We conducted a systematic review of the literature to evaluate the outcomes of endovascular treatment of previously clipped aneurysms. METHODS:A systematic search of MEDLINE, Embase, S...
journal_title：World neurosurgery
pub_type： 杂志文章,meta分析,评审
doi：10.1016/j.wneu.2018.02.103
更新日期：2018-06-01 00:00:00
abstract：BACKGROUND:The neurosurgical boot camp has been fully incorporated into U.S. postgraduate education. This is the first implementation of the neurosurgical boot in a developing country. To advance neurosurgical education, we developed a similar boot camp program, in collaboration with Bolivian neurosurgeons, to determin...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2017.05.046
更新日期：2017-08-01 00:00:00
abstract：BACKGROUND:In vascular reconstructive surgery, intraoperative confirmation of patency is performed by angiography, Doppler, or indocyanine videoangiography, but it is sometimes insufficient. OBJECTIVE:Using the FLOW 800 system (Carl Zeiss, Oberkochen, Germany), we confirmed patency in a quantitative relative evaluatio...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2017.11.072
更新日期：2018-02-01 00:00:00
abstract：OBJECTIVES:Non-small-cell lung cancer (NSCLC) is one of the most common primary tumor sites among patients with metastatic spinal cord compression (MSCC). This disorder is related to neurologic dysfunction and can reduce the quality of life, but the association between MSCC and death is unclear. The aim of this study w...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2017.09.079
更新日期：2017-12-01 00:00:00
abstract：INTRODUCTION:Several methods have been proposed to achieve a watertight dural closure, including the use of fibrin sealant to reinforce sutures. We propose a fast technique using oxidized cellulose and fibrin glue to achieve firm and watertight closure of minor dural defects in supratentorial cranial surgery. TECHNICA...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2010.09.029
更新日期：2011-07-01 00:00:00
abstract：:The roots of modern neurosurgery in Iraq can be traced back to the dawn of civilization, the Mesopotamian culture. Archaeological evidence has provided us with new insights regarding Mesopotamian medical practices. Back then, 2 forms of medicine coexisted: therapeutic and divinatory, which were practiced by the Asu an...
journal_title：World neurosurgery
pub_type： 历史文章,杂志文章,评审
doi：10.1016/j.wneu.2020.05.097
更新日期：2020-08-01 00:00:00
abstract：OBJECTIVE:To assess the efficacy of the combined use of a gasket seal closure and a vascularized pedicle nasoseptal flap (VP-NSF) multilayered reconstruction technique for high-flow cerebrospinal fluid (CSF) leaks resulting from endonasal endoscopic skull base surgery. METHODS:From October 2009-June 2011, a VP-NSF mul...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2014.06.004
更新日期：2015-02-01 00:00:00
abstract：OBJECTIVE:To describe the technical details of 3-piece orbitozygomatic (OZ) craniotomy using a diamond threadwire saw as an alternative to cutting the orbital rim and zygoma. METHODS:The details of this procedure are presented by cadaver dissection and a surgical case. RESULTS:Three-piece OZ craniotomy consists of 3 ...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2019.04.235
更新日期：2019-08-01 00:00:00
abstract：OBJECTIVE:The pathophysiologic mechanisms underlying cerebral vasospasm after aneurysmal subarachnoid hemorrhage (aSAH) remain poorly understand. Ryanodine receptors (RYR) are intracellular calcium channels involved in the regulation of vascular smooth muscle cells and cerebrovascular tone and diameter. Previous work r...
journal_title：World neurosurgery
pub_type： 杂志文章,多中心研究
doi：10.1016/j.wneu.2016.12.132
更新日期：2017-04-01 00:00:00
abstract：OBJECTIVE:To compare circumferential minimally invasive (cMIS) versus open surgeries for mild-to-moderate adult spinal deformity (ASD) with regard to intensive care unit (ICU) and hospital lengths of stay (LOS). METHODS:A retrospective review of 2 multicenter ASD databases with 426 ASD (sagittal vertical axis <6 cm) s...
journal_title：World neurosurgery
pub_type： 杂志文章,多中心研究
doi：10.1016/j.wneu.2019.03.237
更新日期：2019-07-01 00:00:00
abstract：BACKGROUND:For a long time, a combined transcranial and transfacial approach was the gold standard in the aspect of surgical management of large tumors with sinonasal and skull base involvement. The extended endoscopic endonasal approach for such pathologies has its advantages, but flaws as well, such as anatomical lim...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2020.12.150
更新日期：2021-01-05 00:00:00
abstract：:This paper explores the clinical effect of midazolam as an adjuvant analgesic and tranquilizer after brachial plexus block anaesthesia with the aid of medical imaging. The paper selected 106 patients who underwent elective unilateral upper extremity surgery from January 2017 to December 2019, and randomly divided them...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2020.11.101
更新日期：2020-11-26 00:00:00
abstract：BACKGROUND:Based on our experience with the endoscopic endonasal approach (EEA) and transorbital approach (TOA) for middle cranial fossa tumors, we evaluated the efficacy and limitations of visualization and the clinical outcomes associated with the approaches depending on the surgical corridors. In addition, we determ...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2018.11.090
更新日期：2019-02-01 00:00:00
abstract：BACKGROUND:Tumor recurrence or incomplete resection in nonfunctioning pituitary adenomas (NFPAs) is relatively common. However, predictive factors of tumor recurrence in NFPAs are not well established. We evaluated possible factors related to tumor recurrence in a large cohort of NFPAs at a single pituitary neurosurger...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2018.08.043
更新日期：2018-12-01 00:00:00
abstract：:A previously healthy 44-year-old woman presented with a first-time seizure. Magnetic resonance imaging (MRI) revealed a right frontal intraaxial mass extending from the orbitofrontal gyri and gyrus rectus to the head of the caudate (Video 1). The mass demonstrated heterogeneous signal intensity on precontrast T1-weigh...
journal_title：World neurosurgery
pub_type：
doi：10.1016/j.wneu.2019.12.160
更新日期：2020-04-01 00:00:00
abstract：BACKGROUND:Deep brain stimulation within or adjacent to the subthalamic nucleus (STN) represents the most common stereotactic procedure performed for Parkinson disease. Better STN imaging is often regarded as a requirement for improving stereotactic targeting. However, it is unclear whether there is consensus about the...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2016.11.012
更新日期：2017-03-01 00:00:00
abstract：BACKGROUND:Consistent data on head injury is lacking especially in the low- and middle-income countries. Our study tries to characterize patients with head injury at the emergency department of one of the few tertiary public hospitals giving neurosurgical care in the country. METHODS:A retrospective cross-sectional st...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2019.03.044
更新日期：2019-07-01 00:00:00
abstract：BACKGROUND:Myoclonic dystonia syndrome (MDS) is a rare inherited movement disorder characterized by the coexistence of myoclonic jerks and dystonia. Deep brain stimulation (DBS) is a promising treatment for patients with MDS that targets the globus pallidus internus or ventral intermediate nucleus (Vim) of the thalamus...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2018.10.177
更新日期：2019-02-01 00:00:00
abstract：BACKGROUND:As ancient Greeks started looking for deities that could fulfill the pragmatic needs of common people, local heroes started being mythologized and worshipped through cults. METHODS:The most widespread such example was Asclepius, possibly a skilled war surgeon who followed military expeditions to Colchis and...
journal_title：World neurosurgery
pub_type： 历史文章,杂志文章,评审
doi：10.1016/j.wneu.2017.04.022
更新日期：2017-07-01 00:00:00
abstract：BACKGROUND:The benefit of prophylactic antibiotic use in endoscopic endonasal transsphenoidal surgery (EETS) for pituitary lesions is controversial. Many surgeons administer antibiotics perioperatively not based on clear guidelines but to be safe. The purpose of this study was to determine if antibiotic prophylaxis use...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2019.05.082
更新日期：2019-08-01 00:00:00
abstract：BACKGROUND:Patients with an aneurysmal subarachnoid hemorrhage (aSAH) and World Federation of Neurosurgical Societies (WFNS) grade I on admission are generally considered to have a good clinical outcome. OBJECTIVE:The objective of this study was to assess the actual clinical outcome of WFNS grade I aSAH patients, and ...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2018.06.157
更新日期：2018-10-01 00:00:00
abstract：BACKGROUND AND IMPORTANCE:Lesions located lateral to the lower brainstem, such as proximal posterior inferior cerebellar artery (PICA) aneurysms, are surgically challenging. We report a case of a patient with a left proximal PICA aneurysm that was successfully clipped via a so-called "extended" suboccipital subtonsilla...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2018.06.019
更新日期：2018-09-01 00:00:00
abstract：BACKGROUND:During the past 3 decades, a handful of spinal dural arteriovenous fistula cases have been reported in which the segmental artery giving rise to the fistulous connection also supplies a radiculomedullary artery that contributes to the anterior spinal artery. CASE DESCRIPTION:Here, we describe the case of a ...
journal_title：World neurosurgery
pub_type： 杂志文章,评审
doi：10.1016/j.wneu.2016.10.102
更新日期：2017-01-01 00:00:00
abstract：OBJECTIVE:Direct surgery for complex internal carotid artery (ICA) aneurysms can be difficult. In certain situations, sacrificing the parent artery is a unique way to obliterate the aneurysm and extracranial-to-intracranial (EC-IC) bypass is indispensable to prevent postoperative cerebral ischemia. This article discuss...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2010.07.043
更新日期：2011-03-01 00:00:00
abstract：:The degree of primary resection of malignant brain gliomas (MBGs) has correlated positively with progression-free and overall survival. The indications for surgery and reoperation in MBG relapse remain controversial. Surgery will not be curative and should be followed by adjuvant treatment. We reviewed the reported st...
journal_title：World neurosurgery
pub_type： 历史文章,杂志文章,评审
doi：10.1016/j.wneu.2019.09.037
更新日期：2019-12-01 00:00:00
abstract：OBJECTIVE:Fluorescence guidance has a demonstrated potential in maximizing the extent of high-grade glioma resection. Different fluorophores (fluorescent biomarkers), including 5-aminolevulinic acid (5-ALA) and fluorescein, have been examined with the use of several imaging techniques. Our goal was to review the state ...
journal_title：World neurosurgery
pub_type： 杂志文章,meta分析,评审
doi：10.1016/j.wneu.2013.06.014
更新日期：2014-07-01 00:00:00
abstract：OBJECTIVE:As a result of the resolution of intravoxel fiber crossing, high-resolution fiber tractography (HRFT) provides advantages over conventional diffusion tensor imaging (DTI) for fiber tractography (FT). Nevertheless, neurosurgically applied FT is still predominantly based on DTI. Although the application of HRFT...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2019.10.138
更新日期：2020-02-01 00:00:00
