Abstract:
:Isotonic saline is a widely-used infusion fluid, although the associated chloride load may cause metabolic acidosis and impair kidney function in young, healthy volunteers. We wished to examine whether these effects also occurred in the elderly, and conducted a crossover study in 13 men with a mean age of 73 years (range 66-84), who each received intravenous infusions of 1.5 l of Ringer's acetate and of isotonic saline. Isotonic saline induced mild changes in plasma sodium (mean +1.5 mmol.l(-1) ), plasma chloride (+3 mmol.l(-1) ) and standard bicarbonate (-2 mmol.l(-1) ). Three hours after starting the infusions, 68% of the Ringer's acetate and 30% of the infused saline had been excreted (p < 0.01). The glomerular filtration rate increased in response to both fluids, but more after the Ringer's acetate (p < 0.03). Pre-infusion fluid retention, as evidenced by high urinary osmolality (> 700 mOsmol.kg(-1) ) and/or creatinine (> 7 mmol.l(-1) ), was a strong factor governing the responses to both fluid loads.
journal_name
Anaesthesiajournal_title
Anaesthesiaauthors
Hahn RG,Isacson MN,Fagerström T,Rosvall J,Nyman CRdoi
10.1111/anae.13301subject
Has Abstractpub_date
2016-02-01 00:00:00pages
155-62issue
2eissn
0003-2409issn
1365-2044journal_volume
71pub_type
杂志文章相关文献
ANAESTHESIA文献大全abstract::The statement that amniotic fluid embolism is the most dangerous and untreatable condition in obstetrics appears to be true. It must be suspected in any patient who collapses or bleeds excessively during labour or the immediate post-partum period. Attempts should be made to secure a definitive diagnosis in life by exa...
journal_title:Anaesthesia
pub_type: 杂志文章,评审
doi:10.1111/j.1365-2044.1979.tb04862.x
更新日期:1979-01-01 00:00:00
abstract::Amniotic fluid embolism is a rare obstetric complication. The exact pathogenesis of this syndrome remains unknown and significant controversy exists whether coagulopathy should always be present. We used thromboelastography to assess the effect of amniotic fluid on coagulation and platelet function in pregnant women. ...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.2005.04373.x
更新日期:2005-11-01 00:00:00
abstract::Neurotoxicity manifesting as convulsions is a recognised complication of the administration of local anaesthetic drugs as part of a regional anaesthetic technique. We describe a case of self-limiting convulsions following the institution of an axillary brachial plexus block with levobupivacaine. Although the occurrenc...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1046/j.1365-2044.2002.02860.x
更新日期:2002-12-01 00:00:00
abstract::Pre-operative anaemia is associated with poor outcomes after elective surgery but its relationship with outcomes after emergency surgery is unclear. We analysed National Emergency Laparotomy Audit data from 1 December 2013 to 30 November 2017, excluding laparotomy for haemorrhage. Anaemia was classified as 'mild' 129-...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/anae.15021
更新日期:2020-07-01 00:00:00
abstract::A relationship between cardiac output and the onset time of neuromuscular blockade administered into a peripheral vein was evaluated in 41 adult patients. Anaesthesia was induced with midazolam and fentanyl and maintained with intermittent doses of fentanyl and 66% nitrous oxide in oxygen. After immobilisation of the ...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1995.tb04619.x
更新日期:1995-04-01 00:00:00
abstract::A case history is presented of a woman with known Wolff-Parkinson-White syndrome who, in late pregnancy, developed repeated supraventricular tachycardia, requiring direct current cardioversion. The anaesthetic problems and some pharmacological aspects of the management are discussed. ...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1981.tb10325.x
更新日期:1981-06-01 00:00:00
abstract::Data are presented for anaesthesia for Caesarean section (CS) in the South-west Thames region of the UK. The CS rate rose from 12.7% in 1987 to 24.2% in 2002. The rate of increase shows no sign of slowing. The rate of regional anaesthesia (RA) for elective CS rose from 69.4% in 1992 to 94.9% in 2002, when spinal anaes...
journal_title:Anaesthesia
pub_type: 杂志文章,多中心研究
doi:10.1046/j.1365-2044.2003.03446.x
更新日期:2003-11-01 00:00:00
abstract::Vecuronium was administered to patients in doses of 100, 150, 200 and 250 micrograms/kg and the duration of action recorded by noting the time to recovery of the first twitch in a train-of-four to 10% of the control twitch. The recovery times ranged from a mean of 28.4 minutes (100 micrograms/kg) to 72.4 minutes (250 ...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1987.tb03000.x
更新日期:1987-02-01 00:00:00
abstract::Sixty-two children were randomly allocated to receive, during inhalational anaesthesia with isoflurane and nitrous oxide, either 1.0 microg x kg(-1) remifentanil (n = 33) or saline (n = 29) just before the tunnelling phase of ventriculoperitoneal shunt insertion, in a double-blind study. The remifentanil group showed ...
journal_title:Anaesthesia
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1046/j.0003-2409.2001.02398.x
更新日期:2002-02-01 00:00:00
abstract::A case is described in which a woman with well controlled epilepsy and minor abnormalities of peripheral nerve function in the lower limbs experienced intense pain during the onset of a spinal anaesthetic for operation on burns on her thighs. Possible mechanisms and treatments are discussed. ...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1990.tb14335.x
更新日期:1990-06-01 00:00:00
abstract::Twenty-six patients received oral temazepam and subsequently spinal anaesthesia. Blood and lumbar cerebrospinal fluid temazepam levels were measured together with the degree of sedation. The plasma and cerebrospinal fluid concentrations correlated well with the temazepam dose but even better with the weight standardis...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1992.tb02169.x
更新日期:1992-04-01 00:00:00
abstract::We report the findings of a study on exposure of operating room staff to sevoflurane, halothane and nitrous oxide during induction and maintenance of anaesthesia in children. Concentrations of anaesthetic agents in the operating theatre were measured directly by highly sensitive, photoacoustic infrared spectrometer du...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1997.070-az0061.x
更新日期:1997-03-01 00:00:00
abstract::Implementation of a quality improvement bundle for peri-operative management of emergency laparotomy (ELPQuIC) improved mortality in a previous study. We used data from one site that participated in that study to examine whether it was associated with the cost of care. We collected data from 396 patients: 144 before, ...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/anae.13623
更新日期:2016-11-01 00:00:00
abstract::To assess the potential for atmospheric nitrogen to enter the nonventilated lung following the initiation of single-lung ventilation, the nonventilated lung of 10 patients undergoing video-assisted thoracoscopy was connected to the air in a water-filled spirometer, and gas movement out of and back into the lung was me...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1046/j.1365-2044.1999.00845.x
更新日期:1999-05-01 00:00:00
abstract::A case is presented in which the inhalation of a foreign body caused a respiratory arrest and was subsequently diagnosed and treated as an attack of acute asthma. The presentation, diagnosis, investigation and treatment of this condition is discussed and a review of the literature is presented. ...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1986.tb13177.x
更新日期:1986-02-01 00:00:00
abstract::Allogeneic red cell transfusion is a commonly used treatment to improve the oxygen carrying capacity of blood during the peri-operative period. Increasing arterial oxygen content by increasing haemoglobin does not necessarily increase tissue oxygen delivery or uptake. Although the evidence-base for red cell transfusio...
journal_title:Anaesthesia
pub_type: 杂志文章,评审
doi:10.1111/anae.12893
更新日期:2015-01-01 00:00:00
abstract::The absorption of morphine 10 mg after intramuscular injection into the gluteal and deltoid muscles was investigated. Ten patients received the injection into the deltoid and 10 were given the injection into the upper outer quadrant of the buttock. Blood was taken at frequent intervals up to 2 hours after the injectio...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1988.tb08976.x
更新日期:1988-04-01 00:00:00
abstract::We compared the use of sevoflurane and propofol with three different doses of rocuronium for modified rapid-sequence induction of anaesthesia. One hundred and forty adult patients were randomly allocated to have a rapid-sequence intravenous induction with propofol 2-3 mg.kg-1 (group P) or an inhalational induction wit...
journal_title:Anaesthesia
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1046/j.1365-2044.1999.00745.x
更新日期:1999-03-01 00:00:00
abstract::Phaeochromocytoma can mimic many serious disease entities. This report describes a 43-year-old man who presented with pulmonary oedema due to a phaeochromocytoma. Predominantly adrenaline-secreting tumours seem to predispose to this complication. Labetalol, a combined alpha- and beta-receptor blocker, should be consid...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1987.tb03092.x
更新日期:1987-06-01 00:00:00
abstract::The laryngeal mask airway was inserted in 10 cadavers. At postmortem the chest was opened and an infusion set primed with a dilute barium solution was inserted into the oesophagus and ligated in place. A cricoid force of 43 N was then applied and the infusion set was positioned so that when the clamp was opened it gen...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1992.tb03138.x
更新日期:1992-10-01 00:00:00
abstract::A caudal epidural injection was performed on a middle-aged woman for pain in her right foot. Although the procedure was uncomplicated and a good epidurogram was obtained, the patient went on to develop an orthostatic headache with generalised weakness and syncopal episodes that were treated successfully by epidural bl...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.2011.06980.x
更新日期:2012-04-01 00:00:00
abstract::We prospectively assessed common clinical endpoints for their usefulness in avoiding hyperinflation of the cuffs of laryngeal mask airways (slight outward movement) and tracheal tubes (disappearance of an audible leak around the cuff during manual ventilation < 20 cm H(2)O) in 640 children. Cuff pressures were measure...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.2008.05486.x
更新日期:2008-07-01 00:00:00
abstract::A multicentre trial of the use of the intubating laryngeal mask was carried out at seven centres in the United Kingdom using the same agreed protocol. Lung ventilation followed by blind tracheal intubation through the intubating laryngeal mask was attempted on 500 ASA grade 1 and 2 patients. It was possible to insert ...
journal_title:Anaesthesia
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1046/j.1365-2044.1998.00614.x
更新日期:1998-12-01 00:00:00
abstract::National Confidential Enquiry into Patient Outcome and Death guidelines for urgent surgery recommend a fully staffed emergency operating theatre and restriction of 'after-midnight' operating to immediate life-, limb- or organ-threatening conditions. Audit performed in our institution demonstrated significant decreases...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.2008.05441.x
更新日期:2008-06-01 00:00:00
abstract::Target controlled infusions of propofol use a pharmacokinetic/pharmacodynamic model to calculate an effect site concentration of the drug. We assessed the cardiovascular stability of 10 healthy patients using non-invasive thoracic bioimpedance and their 'depth' of anaesthesia using the Bispectral index after they had ...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.2007.05315.x
更新日期:2008-02-01 00:00:00
abstract::A previously unreported hazard of free-standing 'Tec' type vaporizers relating to their positioning downstream of the oxygen flush is presented. Three Enfluratec Mark III vaporizers were studied; measurement of delivered enflurane concentration was performed at a flow rate of 8 litres/minute, during and after the appl...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1985.tb10946.x
更新日期:1985-07-01 00:00:00
abstract::Global Oximetry (GO) is an initiative launched recently in Uganda, India, the Philippines and Vietnam. The overall aims are to promote oximetry utilisation and reduce oximetry costs in lower income countries. Research objectives include studying the feasibility of cost reduction; overcoming non-cost barriers to global...
journal_title:Anaesthesia
pub_type: 杂志文章,评审
doi:10.1111/j.1365-2044.2007.05305.x
更新日期:2007-12-01 00:00:00
abstract::One hundred and fifty women in labour provided with extradural analgesia were monitored and an incidence of Horner's syndrome of 1.33% was noted. Fifty women undergoing Caesarean section under extradural analgesia were also monitored and an incidence of Horner's syndrome of 4% was noted. From the results we found it i...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:
更新日期:1983-06-01 00:00:00
abstract::We performed a randomised, double-blind, prospective trial to discover whether intravenous ketorolac 10 mg made up to 2 ml with saline, with or without venous occlusion for 2 min, reduces the pain on injection of propofol. In 90 patients, pain scores were obtained during injection of propofol following pretreatment of...
journal_title:Anaesthesia
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1046/j.1365-2044.2000.01320.x
更新日期:2000-03-01 00:00:00
abstract::Treatment of postpartum haemorrhage because of uterine atony with intramyometrial prostaglandin E2 1 mg, in an anaesthetised patient resulted in life-threatening hypotension. Anaesthetists should be aware of the potential cardiovascular side effects of prostaglandins. ...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1990.tb14569.x
更新日期:1990-10-01 00:00:00