Abstract:
:Currently, there is much debate on the genetic architecture of quantitative traits in wild populations. Is trait variation influenced by many genes of small effect or by a few genes of major effect? Where is additive genetic variation located in the genome? Do the same loci cause similar phenotypic variation in different populations? Great tits (Parus major) have been studied extensively in long-term studies across Europe and consequently are considered an ecological 'model organism'. Recently, genomic resources have been developed for the great tit, including a custom SNP chip and genetic linkage map. In this study, we used a suite of approaches to investigate the genetic architecture of eight quantitative traits in two long-term study populations of great tits--one in the Netherlands and the other in the United Kingdom. Overall, we found little evidence for the presence of genes of large effects in either population. Instead, traits appeared to be influenced by many genes of small effect, with conservative estimates of the number of contributing loci ranging from 31 to 310. Despite concordance between population-specific heritabilities, we found no evidence for the presence of loci having similar effects in both populations. While population-specific genetic architectures are possible, an undetected shared architecture cannot be rejected because of limited power to map loci of small and moderate effects. This study is one of few examples of genetic architecture analysis in replicated wild populations and highlights some of the challenges and limitations researchers will face when attempting similar molecular quantitative genetic studies in free-living populations.
journal_name
Mol Ecoljournal_title
Molecular ecologyauthors
Santure AW,Poissant J,De Cauwer I,van Oers K,Robinson MR,Quinn JL,Groenen MA,Visser ME,Sheldon BC,Slate Jdoi
10.1111/mec.13452subject
Has Abstractpub_date
2015-12-01 00:00:00pages
6148-62issue
24eissn
0962-1083issn
1365-294Xjournal_volume
24pub_type
杂志文章abstract::We investigated the distribution of genetic variation within and between seven subpopulations in a riparian population of Silene tatarica in northern Finland by using amplified fragment length polymorphism (AFLP) markers. A Bayesian approach-based clustering program indicated that the marker data contained not only on...
journal_title:Molecular ecology
pub_type: 杂志文章
doi:10.1046/j.1365-294x.2003.01898.x
更新日期:2003-08-01 00:00:00
abstract::Modes and mechanisms of speciation are best studied in young species pairs. In older taxa, it is increasingly difficult to distinguish what happened during speciation from what happened after speciation. Lake Victoria cichlids in the genus Pundamilia encompass a complex of young species and polymorphic populations. On...
journal_title:Molecular ecology
pub_type: 杂志文章
doi:10.1111/mec.13838
更新日期:2017-01-01 00:00:00
abstract::The rate of information collection generated by metagenomics is uncoupled with its meaningful ecological interpretation. New analytical approaches based on functional trait-based ecology may help to bridge this gap and extend the trait approach to the community level in vast and complex environmental genetic data sets...
journal_title:Molecular ecology
pub_type: 杂志文章
doi:10.1111/j.1365-294X.2011.05383.x
更新日期:2012-04-01 00:00:00
abstract::The environmental and/or life history factors affecting genetic exchange in marine species with potential for high dispersal are of great interest, not only from an evolutionary standpoint but also with regard to effective management. Previous genetic studies have demonstrated substantial differentiation among populat...
journal_title:Molecular ecology
pub_type: 杂志文章
doi:10.1111/j.1365-294X.2004.02327.x
更新日期:2004-11-01 00:00:00
abstract::Widely distributed taxa provide an opportunity to compare biogeographic responses to climatic fluctuations on multiple continents and to investigate speciation. We conducted the most geographically and genomically comprehensive study to date of the red fox (Vulpes vulpes), the world's most widely distributed wild terr...
journal_title:Molecular ecology
pub_type: 杂志文章
doi:10.1111/mec.12898
更新日期:2014-10-01 00:00:00
abstract::To explore how biogeography, parasite life history and host vagility influences evolutionary codivergences, we followed a comparative phylogeography approach using a host-specific nonpermanent mite, Laelaps giganteus, that occurs on four rodent species within the genus Rhabdomys. A mtDNA COI haplotype network derived ...
journal_title:Molecular ecology
pub_type: 杂志文章
doi:10.1111/mec.13523
更新日期:2016-02-01 00:00:00
abstract::The majority of achlorophyllous mycoheterotrophic plant species associate with arbuscular mycorrhizal fungi (AMF). Previous studies have shown that some species are highly specialized towards narrow lineages of AMF and have suggested that only particular lineages of these fungi are targeted by mycoheterotrophic plants...
journal_title:Molecular ecology
pub_type: 杂志文章
doi:10.1111/j.1365-294X.2012.05472.x
更新日期:2012-03-01 00:00:00
abstract::Possible effects of habitat fragmentation on the population genetics of a species of wolf spider (Lycosidae) from remnant Callitris woodland in the wheat belt of central western New South Wales in Australia are examined. Single-strand conformational analysis of mitochondrial cytochrome oxidase (subunit 1) was used to ...
journal_title:Molecular ecology
pub_type: 杂志文章
doi:10.1046/j.1365-294x.2002.01626.x
更新日期:2002-11-01 00:00:00
abstract::Conservation programmes aim at maximizing the survival probability of populations, by minimizing the loss of genetic diversity, which allows populations to adapt to changes, and controlling inbreeding increases. The best known strategy to achieve these goals is optimizing the contributions of the parents to minimize g...
journal_title:Molecular ecology
pub_type: 杂志文章
doi:10.1111/mec.12560
更新日期:2013-12-01 00:00:00
abstract::Isolation by adaptation increases divergence at neutral loci when natural selection against immigrants reduces the rate of gene flow between different habitats. This can occur early in the process of adaptive divergence and is a key feature of ecological speciation. Despite the ability of isolation by distance (IBD) a...
journal_title:Molecular ecology
pub_type: 杂志文章
doi:10.1111/j.1365-294X.2012.05454.x
更新日期:2012-05-01 00:00:00
abstract::The Monotropoideae (Ericaceae) are non-photosynthetic angiosperms that obtain fixed carbon from basidiomycete ectomycorrhizal fungi. In previous work, we showed that each plant species is associated with a single genus or a set of closely related genera of ectomycorrhizal fungi. Here we show that the level of specific...
journal_title:Molecular ecology
pub_type: 杂志文章
doi:10.1046/j.0962-1083.2001.01443.x
更新日期:2002-03-01 00:00:00
abstract::Experimental evolution (EE) combined with whole-genome sequencing (WGS) has become a compelling approach to study the fundamental mechanisms and processes that drive evolution. Most EE-WGS studies published to date have used microbes, owing to their ease of propagation and manipulation in the laboratory and relatively...
journal_title:Molecular ecology
pub_type: 杂志文章,评审
doi:10.1111/j.1365-294X.2012.05484.x
更新日期:2012-05-01 00:00:00
abstract::Few chloroplast-based genetic studies have been undertaken for plants of mesic temperate forests in the southern hemisphere and fossil-based models have provided evidence of vegetation history only at the broadest scales in this region. This study investigates the chloroplast DNA phylogeography of Tasmannia lanceolata...
journal_title:Molecular ecology
pub_type: 杂志文章
doi:10.1111/j.1365-294X.2010.04725.x
更新日期:2010-07-01 00:00:00
abstract::How does one species become two? What is the relative importance of selection vs. drift? How many genes are involved, what are their effect sizes and where are they located in the genome? The answers to these questions will inevitably vary from one species to another, but by addressing these questions in a diverse arr...
journal_title:Molecular ecology
pub_type: 评论,杂志文章
doi:10.1111/mec.12314
更新日期:2013-06-01 00:00:00
abstract::There is ample evidence that organisms adapt to their native environment when gene flow is restricted. However, evolution of plastic responses across discrete environments is less well examined. We studied divergence in means and plasticity across wild and hatchery populations of sea-run brown trout (Salmo trutta) in ...
journal_title:Molecular ecology
pub_type: 杂志文章
doi:10.1111/j.1365-294X.2012.05590.x
更新日期:2012-06-01 00:00:00
abstract::Transcontinental migration is a fascinating example of how animals can respond to climatic oscillation. Yet, quantitative data on fitness components are scarce, and the resulting population genetic consequences are poorly understood. Migratory divides, hybrid zones with a transition in migratory behaviour, provide a n...
journal_title:Molecular ecology
pub_type: 杂志文章
doi:10.1111/mec.13521
更新日期:2016-06-01 00:00:00
abstract::Although the importance of host plant chemistry in plant-insect interactions is widely accepted, the genetic basis of adaptation to host plants is not well understood. Here, we investigate transcriptional changes associated with a host plant shift in Drosophila mettleri. While D. mettleri is distributed mainly through...
journal_title:Molecular ecology
pub_type: 杂志文章
doi:10.1111/mec.13388
更新日期:2015-10-01 00:00:00
abstract::Breeding indigenous African taurine cattle tolerant to trypanosomosis is a straightforward approach to control costs generated by this disease. A recent study identified quantitative trait loci (QTL) underlying trypanotolerance traits in experimental crosses between tolerant N'Dama and susceptible Boran zebu cattle. A...
journal_title:Molecular ecology
pub_type: 杂志文章
doi:10.1111/j.1365-294X.2009.04141.x
更新日期:2009-04-01 00:00:00
abstract::The Baltic Sea provides a unique model system for studying genetic effects of postglacial colonization and ecological differentiation, because all marine organisms must have immigrated after the opening of the Danish Straits 8000 years ago and responded to the development of the steep Skagerrak-Baltic salinity gradien...
journal_title:Molecular ecology
pub_type: 杂志文章
doi:10.1046/j.1365-294x.2002.01601.x
更新日期:2002-10-01 00:00:00
abstract::Defence against pathogenic infection can take two forms: resistance and tolerance. Resistance is the ability of the host to limit a pathogen burden, whereas tolerance is the ability to limit the negative consequences of infection at a given level of infection intensity. Evolutionarily, a tolerance strategy that is ind...
journal_title:Molecular ecology
pub_type: 杂志文章
doi:10.1111/mec.14017
更新日期:2017-03-01 00:00:00
abstract::In the legume-rhizobia mutualism, the benefit each partner derives from the other depends on the genetic identity of both host and rhizobial symbiont. To gain insight into the extent of genome × genome interactions on hosts at the molecular level and to identify potential mechanisms responsible for the variation, we e...
journal_title:Molecular ecology
pub_type: 杂志文章
doi:10.1111/mec.14285
更新日期:2017-11-01 00:00:00
abstract::Hypotheses of diversification in eastern North American freshwater fishes have focused primarily on allopatric distributions of species between disjunct highland areas and major river systems. However, these hypotheses do not fully explain the rich diversity of species within highland regions and river systems. Relati...
journal_title:Molecular ecology
pub_type: 杂志文章
doi:10.1111/j.1365-294X.2010.04866.x
更新日期:2010-11-01 00:00:00
abstract::We evaluate the relative effectiveness of four methods for preserving faecal samples for DNA analysis. PCR assays of fresh faecal samples collected from free-ranging baboons showed that amplification success was dependent on preservation method, PCR-product size, and whether nuclear or mitochondrial DNA was assayed. S...
journal_title:Molecular ecology
pub_type: 杂志文章
doi:10.1046/j.1365-294x.1998.00449.x
更新日期:1998-10-01 00:00:00
abstract::We investigated the relationship between genomic and phenotypic evolution among replicate populations of Escherichia coli evolved for 1000 generations in four different environments. By resequencing evolved genomes, we identified parallel changes in genes encoding transcription regulators within and between environmen...
journal_title:Molecular ecology
pub_type: 杂志文章
doi:10.1111/mec.12312
更新日期:2013-06-01 00:00:00
abstract::Population differentiation (PD) and ecological association (EA) tests have recently emerged as prominent statistical methods to investigate signatures of local adaptation using population genomic data. Based on statistical models, these genomewide testing procedures have attracted considerable attention as tools to id...
journal_title:Molecular ecology
pub_type: 杂志文章,评审
doi:10.1111/mec.13513
更新日期:2016-01-01 00:00:00
abstract::Colour vision varies within the family Atelidae (Primates, Platyrrhini), which consists of four genera with the following cladistic relationship: {Alouatta[Ateles (Lagothrix and Brachyteles)]}. Spider monkeys (Ateles) and woolly monkeys (Lagothrix) are characteristic of platyrrhine monkeys in possessing a colour visio...
journal_title:Molecular ecology
pub_type: 杂志文章
doi:10.1111/j.1365-294X.2005.02822.x
更新日期:2006-02-01 00:00:00
abstract::The repeated evolution of similar phenotypes by similar mechanisms can be indicative of local adaptation, constraints or biases in the evolutionary process. Little is known about the incidence of physiological convergence in natural populations, so here we test whether energy metabolism in 'dwarf' and 'normal' Lake Wh...
journal_title:Molecular ecology
pub_type: 杂志文章
doi:10.1111/mec.13847
更新日期:2017-01-01 00:00:00
abstract::The Mediterranean Sea is a two-basin system, with the boundary zone restricted to the Strait of Sicily and the narrow Strait of Messina. Two main population groups are recognized in the Mediterranean endemic seagrass Posidonia oceanica, corresponding to the Western and the Eastern basins. To address the nature of the ...
journal_title:Molecular ecology
pub_type: 杂志文章
doi:10.1111/j.1365-294X.2009.04462.x
更新日期:2010-02-01 00:00:00
abstract::Anthyllis montana is a submediterranean, herbaceous plant of the southern and central European mountains. The internal transcribed spacer (ITS) regions of nuclear ribosomal DNA were sequenced from multiple accessions of the species and several closely related taxa. In addition, amplified fragment length polymorphism (...
journal_title:Molecular ecology
pub_type: 杂志文章
doi:10.1046/j.1365-294x.2002.01446.x
更新日期:2002-03-01 00:00:00
abstract::Microbes have evolved ways of interference competition to gain advantage over their ecological competitors. The use of secreted killer toxins by yeast cells through acquiring double-stranded RNA viruses is one such prominent example. Although the killer behaviour has been well studied in laboratory yeast strains, our ...
journal_title:Molecular ecology
pub_type: 杂志文章
doi:10.1111/mec.13310
更新日期:2015-08-01 00:00:00