Abstract：
:Inorganic arsenic (As) is one of the most toxic pollutants in the water. We have studied their effects on the marine teleost European sea bass (Dicentrarchus labrax) at 2 and 10 days of 5 μM of As2O3 (sub-lethal doses) waterborne exposure. Arsenic accumulates in liver and gill tissues. The expression profile of five genes (bax, blc2, casp3, casp8 and casp9) involved in apoptosis cell death confirmed apoptotic effects in liver, slight changes in gill and no effects in skin according with the histopathology findings. Total IgM level and peroxidase activities were increased at 2 and 10 days, respectively. The bactericidal activity was decreased at 2 days after As exposure. A general decrease of cellular immune activities with significant differences in the case of respiratory burst activity was observed after 2 and 10 days of exposure. This work describes for the first time the effects of As exposure on European sea bass.
journal_name
Mar Pollut Bulljournal_title
Marine pollution bulletinauthors
Cordero H,Morcillo P,Martínez S,Meseguer J,Pérez-Sirvent C,Chaves-Pozo E,Martínez-Sanchez MJ,Cuesta A,Ángeles Esteban Mdoi
10.1016/j.marpolbul.2018.01.052subject
Has Abstractpub_date
2018-03-01 00:00:00pages
324-332eissn
0025-326Xissn
1879-3363pii
S0025-326X(18)30063-8journal_volume
128pub_type
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