Abstract:
OBJECTIVE:To determine the impact of physicians' financial relationships with the pharmaceutical industry on prescribing marketed alpha-blockers and overactive bladder (OAB) medications. We also aim to examine if the number or total value of transactions is influential. MATERIALS AND METHODS:We linked the Open Payments Program database of industry payments to prescribers with Medicare Part D prescription data. We used binomial logistic regression to identify the association between receipt of industry payment and prescribing of marketed alpha-blockers (silodosin) and OAB medications (fesoterodine, solifenacin, and mirabegron). We also evaluated the impact of increasing total value and number of payments on prescribing of marketed drugs. RESULTS:The receipt of industry payment was associated with increased odds of prescribing the marketed drug for all included drugs: silodosin (odds ratio [OR] 34.1), fesoterodine (OR 5.9), solifenacin (OR 2.7), and mirabegron (OR 6.8) (all P <.001). We also found that increasing value of total payment and increasing frequency of payments were both independently associated with increased odds of prescribing with a dose-response effect. CONCLUSION:There is a consistent association between receipt of industry payment and prescribing marketed alpha-blockers and OAB medications. Both the total value and number of transactions were associated with prescribing.
journal_name
Urologyjournal_title
Urologyauthors
Modi PK,Wang Y,Kirk PS,Dupree JM,Singer EA,Chang SLdoi
10.1016/j.urology.2018.04.008subject
Has Abstractpub_date
2018-07-01 00:00:00pages
50-56eissn
0090-4295issn
1527-9995pii
S0090-4295(18)30326-1journal_volume
117pub_type
杂志文章相关文献
UROLOGY文献大全abstract:OBJECTIVES:To investigate the clinical utility of fluorescence in situ hybridization (FISH) of voided urine in the detection of bladder cancer and the prediction of its recurrence. METHODS:FISH with centromere-specific probes for chromosomes 9 and 17 was performed to evaluate the chromosomal alterations of exfoliated ...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/s0090-4295(00)01074-8
更新日期:2001-04-01 00:00:00
abstract:OBJECTIVES:To determine the clinical implication of the loss of transforming growth factor-beta (TGF-beta) receptor (TbetaR) expression for the pathologic features in renal cell carcinoma (RCC) and the prognosis of 62 patients (Stage I, 4; Stage II, 28; Stage III, 11; and Stage IV, 19) who underwent radical nephrectomy...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/s0090-4295(02)02553-0
更新日期:2003-05-01 00:00:00
abstract:OBJECTIVE:To investigate the effect of hyperglycemia on the expression of the aquaporin (AQP) isoforms in the diabetic rat vagina. METHODS:Female Sprague-Dawley rats (230-240 g, n = 45) were divided into control (n = 10) and experimental (n = 35) groups. Diabetes in the experimental group was induced by intraperitonea...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2012.03.026
更新日期:2012-09-01 00:00:00
abstract::Numerically weak correlations can stem from research studies for numerous reasons, some of which have little to do with lack of true physiologic relationships. Previous investigators have reported relatively weak correlations among urologic measures, mostly based on patients referred to urologic clinics. Such samples ...
journal_title:Urology
pub_type: 杂志文章,评审
doi:10.1016/s0090-4295(98)00049-1
更新日期:1998-04-01 00:00:00
abstract::A literature review of PubMed reveals that 1 case report is found of a retained Foley catheter for 3 years. We report a case of a straight catheter lost in the urethra and forgotten for 20 years and its safe surgical removal. The calcified straight catheter was removed through a perineal urethrostomy and incision at t...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2010.01.063
更新日期:2011-01-01 00:00:00
abstract::In the evaluation of 116 renal masses 91 (80%) were interpreted as cystic and 25 (20%) as solid. Additional evaluation by arteriography and finally surgery showed that 3 of the 25 initially believed to be solid proved to be cystic. These three renal masses with internal echoes on ultrasound were found at surgery to be...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/0090-4295(77)90367-3
更新日期:1977-03-01 00:00:00
abstract::We report a case of autosomal recessive polycystic kidney disease (ARPKD). A presumptive diagnosis was made after a late-term prenatal ultrasound revealed hypoplastic lungs, massive polycystic kidneys, and oligohydramnios. A full-term baby girl was delivered vaginally. Respiratory distress required intubation. Twelve ...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/s0090-4295(99)00362-3
更新日期:1999-12-01 00:00:00
abstract:OBJECTIVES:Complete and reliable infiltration of the entire prostate is important to improve the efficacy of intraprostatic gene therapy, as well as drug delivery. We sought to evaluate the optimal injection scheme and feasibility of magnetic resonance imaging (MRI) using a surrogate solution to assess the distribution...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2007.06.637
更新日期:2007-10-01 00:00:00
abstract::A retrospective study was made of 200 patients undergoing transurethral prostatectomy. Half of these patients received bilateral vasectomies. The vasectomized patients had a 5-percent incidence of epididymitis as compared with a 2-percent incidence in the nonvasectomized patients. Vasectomy failed to provide adequate ...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/0090-4295(79)90281-4
更新日期:1979-02-01 00:00:00
abstract:OBJECTIVES:To investigate the feasibility, safety, and efficacy of perineal cutaneous application of capsaicin as a test for the diagnosis, as well as a potential therapeutic tool, in patients with chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS). METHODS:We recruited 22 patients (mean age 34.5 years, range ...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2005.11.028
更新日期:2006-05-01 00:00:00
abstract:OBJECTIVE:To validate the Advanced Scope Trainer (AST; Mediskills, Northampton, UK). The AST is a currently unvalidated simulator, developed for flexible ureterorenoscopy (fURS) training. This study aims to assess the face, content, construct, and concurrent validity to assess the level of transferability of skills to ...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2017.07.047
更新日期:2017-12-01 00:00:00
abstract::A contracted empty scrotum in a young man will not accept an artificial testis satisfactorily using any of the standard techniques. Previous operative scars, as from a failed orchiopexy, have often added to the difficulties. Greatly enlarging the scrotum by gradual distention of a tissue expander implanted in the cont...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/0090-4295(89)90056-3
更新日期:1989-01-01 00:00:00
abstract:OBJECTIVES:To examine the usefulness of pretreatment testicular sperm extraction because some patients have tumor-induced azoospermia. In view of the high cure rates for testicular germ cell tumors and malignant lymphomas, increasing clinical importance is attached to protecting fertility. High-dose cytostatic therapy ...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/s0090-4295(02)02264-1
更新日期:2003-02-01 00:00:00
abstract::A 40-year-old male with presented to the clinic with the chief complaint of right inguinal pain radiating to his right testicle and right thigh with no history of trauma, fever, chills, dysuria, hematuria, or unprotected sexual activity. Physical exam revealed right testicular tenderness with no palpable abnormality o...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2020.05.046
更新日期:2020-09-01 00:00:00
abstract::Urethral diverticulum is a correctable cause of lower urinary tract symptoms in women. It has been found to be present in from 1.85 to 4.7 per cent of all females. The postvoid film of the intravenous urogram (IVP) is the simplest and least invasive method available to diagnose urethral diverticula. It should be a rou...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/0090-4295(81)90280-6
更新日期:1981-04-01 00:00:00
abstract::Spontaneous perforation complicating augmentation cystoplasty is reported to occur in ≤ 13% of cases. The standard treatment is open surgical repair of the perforation. To our knowledge, this is the first report of laparoscopic repair of a perforated augmentation cystoplasty. ...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2012.10.033
更新日期:2013-02-01 00:00:00
abstract:OBJECTIVE:To determine whether intratrigonal Onabotulinum toxin A (OnabotA) injection produces a different symptomatic outcome and duration of effect on ulcerative (Ulc) and nonulcerative (NUlc) bladder pain syndrome/interstitial cystitis (BPS/IC) patients and to compare the urinary levels of neurotrophines (NGF, BDNF,...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2014.01.018
更新日期:2014-05-01 00:00:00
abstract:OBJECTIVES:To evaluate the efficacy, safety, and tolerability of sildenafil in men with broad-spectrum erectile dysfunction (ED), with reference to age-matched healthy control subjects. METHODS:One hundred eleven patients were enrolled in a randomized, double-blind, placebo-controlled, parallel-group, 12-week, flexibl...
journal_title:Urology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0090-4295(98)00586-x
更新日期:1999-04-01 00:00:00
abstract::A case report of a plasma cell granuloma presenting as a solitary avascular intrarenal mass lesion is presented with angiographic and ultrasonic findings. ...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/0090-4295(76)90066-2
更新日期:1976-07-01 00:00:00
abstract::Three new cases of a rare benign proliferative lesion of the urothelium (nephrogenic adenoma) are hereby added to the existent 58 reported cases. All 3 lesions occurred in the bladder. Two of the 3 cases presented with a history of surgical interventions on the bladder, and the third patient had a history of chronic c...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/0090-4295(85)90169-4
更新日期:1985-11-01 00:00:00
abstract:OBJECTIVE:To evaluate the California Cancer Registry in order to define nonclear cell renal cell cancer (RCC) clinical features and outcomes, identify prognostic variables, and generate hypotheses for further study. METHODS:Patients with invasive RCC tumors in the California Cancer Registry from 1998 to 2009 (n = 38,2...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2013.07.020
更新日期:2013-10-01 00:00:00
abstract::Two patients presented with synchronous Hodgkin's disease and testicular germ cell neoplasms. Both patients are in complete remission following treatment with multidrug chemotherapy and radiation therapy. Despite epidemiologic similarities between Hodgkin's disease and testicular cancer, only 13 cases of their associa...
journal_title:Urology
pub_type: 杂志文章,评审
doi:10.1016/0090-4295(91)80208-o
更新日期:1991-02-01 00:00:00
abstract::The Cavitron Ultrasonic Surgical Aspirator is a unique modality for precise tissue removal which results in increased visibility, reduced bleeding, and shorter operating time when dealing with vascular lesions or organs. Herein, we present our experience in a dog laboratory as well as in a clinical setting with this n...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/s0090-4295(84)80004-7
更新日期:1984-05-01 00:00:00
abstract:OBJECTIVES:To investigate the efficacy of pazopanib, both alone and in combination with docetaxel, in bladder cancer cells. Bladder cancer expresses many potential therapeutic targets of biological agents, including the vascular endothelial growth factor receptor (VEGFR). Pazopanib is a small molecule inhibitor of VEGF...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2011.02.041
更新日期:2011-07-01 00:00:00
abstract:OBJECTIVES:To measure the renal parenchymal volume (RPV) before and after unilateral nephrectomy and investigate the relationship between the RPV and single kidney glomerular filtration rate (GFR). METHODS:From November 2003 to August 2009, 183 patients who had undergone unilateral nephrectomy were enrolled in the pre...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2010.03.063
更新日期:2011-06-01 00:00:00
abstract:OBJECTIVES:To examine the association between alpha-blocker use and sexual dysfunction among men participating in a population-based cohort of men residing in Olmsted County, MN. Lower urinary tract symptoms (LUTS) in men have previously been associated with sexual dysfunction. The use of alpha-adrenergic receptor bloc...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2008.12.080
更新日期:2009-07-01 00:00:00
abstract::We used an endoscopic thin trocar to reestablish the continuity of the completely obliterated urethra in 2 patients. In 1 man the obstruction resulted from a pelvic fracture and in 1 woman from early removal of the urethral catheter after a bladder neck reconstruction. We found this technique safe and effective, and w...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/0090-4295(85)90454-6
更新日期:1985-05-01 00:00:00
abstract::Cutaneous horns of the penis are hyperkeratotic lesions of the skin which arise secondary to chronic irritation. Treatment is local excision with removal of a broad base. Examination of the base is important to rule out carcinoma as the underlying cause of the lesion. A case report is presented and the literature revi...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/0090-4295(87)90184-1
更新日期:1987-08-01 00:00:00
abstract:OBJECTIVES:Determining the genetic changes associated with the development of metastatic prostate cancer is of utmost importance in patient prognosis and therapy. Our goal is to identify genes whose enhanced expression is associated with metastatic prostate cancer. METHODS:Total ribonucleic acid was isolated from pros...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/S0090-4295(96)00207-5
更新日期:1996-09-01 00:00:00
abstract:OBJECTIVES:To evaluate the prevalence of baseline chronic kidney disease (CKD) in a large cohort of patients presenting with renal masses to a tertiary care center, comparing serum creatinine (sCr) and estimated glomerular filtration rate (eGFR). sCr inadequately reflects renal function. eGFR and chronic kidney disease...
journal_title:Urology
pub_type: 杂志文章
doi:10.1016/j.urology.2010.11.050
更新日期:2011-04-01 00:00:00