Abstract：
:Nonylphenol (NP) is a commercially produced nonionic surfactant that has become a global environmental pollutant due to poor biodegradability. Many studies have confirmed that NP has detrimental effects on the central nervous system. However, the damaging roles of NP on the cerebellum and the underlying mechanisms remain unclear. Therefore, we investigated the effects of perinatal exposure to NP on cerebellar Purkinje cell (PC) dendrites and explored the potential mechanism involved. The animal model of perinatal exposure to NP was established by orally administering dams with either corn oil or NP (10, 50, or 100 mg/kg) during pregnancy and lactation. Offspring subjected to NP exposure during pregnancy and lactation had shorter and fewer cerebellar PC dendritic branches in childhood (postnatal day (PND)21) and adulthood (PND80). Contrary to expectations, perinatal NP treatment increased phosphorylation of protein kinase C gamma on PND21, but not on PND80. However, perinatal exposure to NP decreased phosphorylation of stathmin and tropomyosin-related kinase B (TrkB), as well as the expression of brain derived neurotrophic factor (BDNF) in cerebellar PCs on PND21 and PND80. These results indicate that perinatal exposure to NP irreversibly inhibited dendritic growth of PCs in the cerebella of offspring. Furthermore, the irreversible damage to PC dendrites in the cerebella of offspring subjected to perinatal NP exposure may be due to increased stathmin activity mediated by BDNF-TrkB signaling.
journal_name
Chemospherejournal_title
Chemosphereauthors
You M,Gu W,Li M,Qiu Z,Li S,Jiang Z,Yao D,Xu Y,Wang Ydoi
10.1016/j.chemosphere.2018.08.007subject
Has Abstractpub_date
2018-11-01 00:00:00pages
758-766eissn
0045-6535issn
1879-1298pii
S0045-6535(18)31475-9journal_volume
211pub_type
杂志文章相关文献
CHEMOSPHERE文献大全abstract：:The objectives of this work were to study the effect of urea addition to the fuel before the combustion on the suppression of PCDD/F emissions, to examine the influence of urea to PCDD/F isomer patterns by employing statistical analysis techniques and to determine the most effective method of urea addition. Urea in th...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/s0045-6535(00)00248-4
更新日期：2001-02-01 00:00:00
abstract：:In order to understand the residue levels of organochlorine compounds (OCs) and their accumulation patterns in wildlife inhabiting Chubu region, Japan, the concentrations of polychlorinated biphenyls (PCBs), hexachlorocyclohexane isomers (HCHs), DDT compounds (DDTs) and hexachlorobenzene (HCB) were measured in 8 speci...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/s0045-6535(98)00011-3
更新日期：1998-06-01 00:00:00
abstract：:During foraging, bees are exposed to sublethal doses of insecticides, which can cause morphological changes to various organs, such as the midgut, Malpighian tubules, and mushroon body. Thus, the purpose of this study was to establish a scoring system to evaluate these alterations based on the damage caused and its re...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2019.06.225
更新日期：2019-12-01 00:00:00
abstract：:Contamination and analytical variation can significantly hinder trace analysis of cyclic methyl volatile siloxanes (cVMS); potentially resulting in the report of false positives at concentrations approaching detection limits. To assess detection and variation associated with trace cVMS analysis in environmental matric...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2012.10.045
更新日期：2013-10-01 00:00:00
abstract：:In 1979, more than 2000 persons ingested rice oil contaminated with polychlorinated biphenyls and polychlorinated dibenzofurans; this event was called the "Yucheng accident." An increased percentage of oligospermia, reduced ability of sperm to penetrate oocytes, and reduced percentage of male offspring were reported i...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2016.09.035
更新日期：2016-12-01 00:00:00
abstract：:The study provides cumulative data on the status of the two water bodies. The study designed revealed physicochemical properties (temperature, dissolved oxygen, pH, total dissolved solids and conductivity) to be in the desirable range, however, amongst the heavy metals excepting for Cd all were found to be higher than...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2020.126311
更新日期：2020-07-01 00:00:00
abstract：:Jundiá (Rhamdia quelen, Quoy and Gaimard), a South American teleostean fish, was exposed to sub-lethal concentrations of cypermethrin (30% and 45% of the 48-h LC(50) value of 0.265 ppm) for 2, 4 or 8 days. Serum biochemical and hematological values and behavioral changes were studied. The 30% LC(50), 0.08 ppm, produce...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2007.05.068
更新日期：2007-10-01 00:00:00
abstract：:Time of flight secondary ion mass spectroscopy has been used to study the metal distribution at the soil/root interface of tree roots extracted from smelter-impacted soils. The results, augmented by scanning electron microscopy, show that the technique is capable of resolving metal distributions at the cellular level....
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2003.07.010
更新日期：2004-02-01 00:00:00
abstract：:Indo-Pacific humpback dolphins (Sousa chinensis) are apex predators in the Pearl River Estuary waters (PRE) of China. PCBs, DDTs and other organochlorine pesticides (OCPs) (e.g., HCHs, HCB, mirex and dieldrin) were analysed in blubber samples of 45 dolphins and 10 prey fishes of S. chinensis collected from 2004 to 201...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2014.04.028
更新日期：2014-11-01 00:00:00
abstract：:Ogale community in Rivers State, Nigeria is characterized by crude-oil contamination of its land resources. The present study aimed to evaluate the health risk and metal (Cd, Pb, Zn, Cr, and Ni) contamination level of the vegetable (Telfairia occidentalis), snail (Achatina achatina) and the catfish (Clarias gariepinus...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2017.07.024
更新日期：2017-10-01 00:00:00
abstract：:Bacteria can immobilize significant quantities of trace metals through surface complexation reactions. However, bacterial cell lysis is an integral part of the development process, and the extent to which this process affects adsorbed metals has not been properly investigated. In order to evaluate the effects of cell ...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2006.11.050
更新日期：2007-05-01 00:00:00
abstract：:Semipermeable membrane devices (SPMDs) are commonly used as a time-integrated measure of aqueous concentrations of persistent hydrophobic chemicals, including PAH, pesticides, dioxins, and PCBs. Another class of persistent hydrophobic chemicals is petroleum biomarker compounds (hopanes and steranes) that are used for ...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/S0045-6535(03)00576-9
更新日期：2003-11-01 00:00:00
abstract：:Given the millions of coal-fired power stations worldwide and the generalization of co-firing technologies in the near future, the aqueous extraction experiments were taken to study the effects of oxides on Cr mobility in ashes through SiO2-Al2O3-Fe2O3-CaO system. The results identify that both the component and the s...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2020.127112
更新日期：2020-10-01 00:00:00
abstract：:Microplastics in the environment are either a product of the fractionation of larger plastic items or a consequence of the release of microbeads, which are ingredients of cosmetics, through wastewater treatment plant (WWTP) effluents. The aim of this study was to estimate the amount of microbeads that may be released ...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2017.08.131
更新日期：2017-12-01 00:00:00
abstract：:Ten previously unidentified polybrominated dibenzo-p-dioxins (PBDDs) were identified or tentatively identified in samples of Baltic Sea sediment and biota. Five tetrabrominated dibenzo-p-dioxins (TeBDDs) were identified using authentic reference standards, including the four most abundant (previously denoted 4U1 throu...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2009.11.023
更新日期：2010-02-01 00:00:00
abstract：:Aging refers to the processes by which the mobility and bioavailability of metals in soil decline with time. Although long-term aging is a key process that needs to be considered in risk assessment of metals, few investigations has been attempted to determine whether and how residence time influences the selenium (Se)...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2015.11.011
更新日期：2016-02-01 00:00:00
abstract：:A commercially available enzyme-linked immunosorbent assay (ELISA) kit was evaluated for the determination of toxic equivalents (TEQs) of dioxin-like polychlorinated biphenyls (PCBs) in retail fish. The ELISA was highly specific for 2,3',4,4',5-pentachlorobiphenyl (PCB 118), which is generally the most abundant dioxin...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2006.01.059
更新日期：2006-10-01 00:00:00
abstract：:This paper describes a methodological approach for the assessment of the amount of surrogate dry deposition of several toxic heavy metals (Cd, Cr, Cu, Ni, Pb, V, Zn) associated with atmospheric particulate matter at ground level. The objectives of the study were twofold: i) the evaluation of several techniques for the...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/s0045-6535(98)00309-9
更新日期：1999-02-01 00:00:00
abstract：:The green miridbug, Cyrtorhinus lividipennis, an important natural enemy of the rice brown planthopper (BPH), Nilaparvata lugens plays a major role as a predator in suppressing the pest population. The study assessed the impact of certain potential insecticides used in the rice ecosystem on the miridbug predator and b...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2010.04.070
更新日期：2010-07-01 00:00:00
abstract：:This study investigated the effects of exogenous N-acyl-homoserine lactone (AHL) signal molecules, N-hexanoyl-l-homoserine lactone (C6-HSL) and N-octanoyl-l-homoserine lactone (C8-HSL), on treatment performance, sludge properties and microbial community structures in activated sludge systems. Results showed that the n...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2020.126945
更新日期：2020-09-01 00:00:00
abstract：:PCDD/PCDF were determined in solid samples from wood combustion. The samples included grate ashes, bottom ashes, furnace ashes as well as fly and cyclone ashes. The solid waste samples were classified into bottom and fly ash from native wood and bottom and fly ash from waste wood. For each of the four classes concentr...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/s0045-6535(99)00332-x
更新日期：2000-03-01 00:00:00
abstract：:The efficiency of ZnO and TiO(2) suspensions in the photocatalytic degradation of two fungicides (cyprodinil and fludioxonil) in leaching water was investigated. The experiments were carried out at pilot plant scale using compound parabolic collectors under natural sunlight. The blank experiments for both irradiated c...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2011.07.022
更新日期：2011-11-01 00:00:00
abstract：:A batch experiment was conducted to assess the impact of chemical oxidation using modified Fenton reaction on PAH content and on physico-chemical and biological parameters of an industrial PAH contaminated soil in unsaturated condition. Two levels of oxidant (H(2)O(2), 6 and 65 g kg(-1)) and FeSO(4) were applied. Agro...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2011.11.018
更新日期：2012-02-01 00:00:00
abstract：:Enhanced Biological Phosphorus Removal (EBPR) of urban wastewaters is usually limited by the available carbon source required by Polyphosphate Accumulating Organisms (PAO). External carbon sources as volatile fatty acids (VFA) or other pure organic compounds have been tested at lab scale demonstrating its ability to e...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2015.05.067
更新日期：2015-12-01 00:00:00
abstract：:In this work, the photocatalytic degradation of aqueous microcystin-LR was studied using TiO(2) and ZnO as photocatalysts. The process was optimised and characterised at the bench scale (200 mL); both semiconductors exhibited a high degradation capacity at reaction times of 1 min (degradation greater than 95%). The tr...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2012.09.004
更新日期：2013-01-01 00:00:00
abstract：:A laboratory-scale acidogenic anaerobic sequencing batch reactor was set up to test the effect of pH change on microbial community structure of the reactor biomass and process performance. No immediate performance change on acidogenesis was observed after the pH change. However, as the hydrogenotrophic methanogen popu...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2014.10.047
更新日期：2015-12-01 00:00:00
abstract：:The adsorption experiment of nickel ion [Ni(II)] on gamma-type alumina by a differential bed reactor in aqueous solutions was investigated to determine the adsorption characteristics and overall adsorption rate. The adsorbed amount increased rapidly with pH from pH 2 to 6 and kept constant over pH 6. The adsorbed amou...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2003.08.036
更新日期：2004-02-01 00:00:00
abstract：:The complexity of natural dissolved organic matter (DOM) motivates the determination of how DOM from diverse sources affects the environmental behaviors of engineered nanoparticles. Here, three types of DOM, DOM extracted from swine manure (SWDOM), sludge (SLDOM) and sediment (SEDOM), were characterized, and their eff...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2019.124529
更新日期：2019-12-01 00:00:00
abstract：:243 surface soil samples were collected from the Yangtze River Delta (YRD) region, and the concentration distributions and compositional profiles of 27 parent PAHs (PPAHs), nitro- and oxy-derivatives (NPAHs and OPAHs), respectively, and health risk of 16 PPAHs were determined. Atmospheric samples were collected at two...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2017.03.057
更新日期：2017-07-01 00:00:00
abstract：:Co3O4/BiFeO3 nanocomposite catalysts were synthesized by a facile hydrothermal method following the impregnation process. The nanocomposite was successfully characterized by powder X-ray diffraction(XRD), scanning electron microscopy (SEM), high resolution transmission electron microscopy (HRTEM), nitrogen adsorption ...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2018.12.045
更新日期：2019-03-01 00:00:00
