Transcriptional Approach for Decoding the Mechanism of rpoC Compensatory Mutations for the Fitness Cost in Rifampicin-Resistant Mycobacterium tuberculosis.

abstract：:Kaposi sarcoma herpesvirus (KSHV) is the etiologic agent of Kaposi sarcoma (KS) and certain rare B cell lymphoproliferative disorders. KSHV infection of endothelial cells (EC) in vitro increases expression of the inducible host-encoded enzyme heme oxygenase-1 (HO-1), which is also strongly expressed in KS tumors. HO-1...

journal_title：Frontiers in microbiology

authors： Botto S,Gustin JK,Moses AV

更新日期：2017-04-03 00:00:00

abstract：:The gastrointestinal microbiome is crucial in human health. With greater than 10 times the cell count of an individual, the gastrointestinal microbiome provides many benefits to the host. It plays an important role in chronic illnesses and immune diseases and also following burns and trauma. This study aimed to determ...

journal_title：Frontiers in microbiology

authors： Huang G,Sun K,Yin S,Jiang B,Chen Y,Gong Y,Chen Y,Yang Z,Chen J,Yuan Z,Peng Y

更新日期：2017-07-06 00:00:00

abstract：:A vital function of the cell membrane in all living organism is to maintain the membrane permeability barrier and fluidity. The composition of the phospholipid bilayer is distinct in archaea when compared to bacteria and eukarya. In archaea, isoprenoid hydrocarbon side chains are linked via an ether bond to the sn-gly...

journal_title：Frontiers in microbiology

authors： Jain S,Caforio A,Driessen AJ

更新日期：2014-11-26 00:00:00

abstract：:Zinc has an abounding occurrence in the prokaryotes and plays paramount roles including catalytic, structural, and regulatory. Zinc uptake regulator (Zur), a Fur family transcriptional regulator, is connoted in maintaining zinc homeostasis in the pathogenic bacteria by binding to zinc and regulating the genes involved...

journal_title：Frontiers in microbiology

authors： Kandari D,Gopalani M,Gupta M,Joshi H,Bhatnagar S,Bhatnagar R

更新日期：2019-01-11 00:00:00

abstract：:Ocular toxoplasmosis (OT) is one of the most common causes of posterior uveitis. The signaling of triggering receptor expressed on myeloid cells (TREM)-1 amplifies inflammation, whereas TREM-2 signaling is anti-inflammatory. IL-1β is a major driver of inflammation during infection. Toll-like receptors (TLRs) play impo...

journal_title：Frontiers in microbiology

authors： Zhang Y,He J,Zheng H,Huang S,Lu F

更新日期：2019-10-09 00:00:00

abstract：:The efficiency of horizontal gene transfer, which contributes to acquisition and spread of antibiotic resistance and pathogenicity traits, depends on nucleotide sequence and different mismatch-repair (MMR) proteins participate in this process. To study how MutL and MutS MMR proteins regulate recombination across speci...

journal_title：Frontiers in microbiology

authors： Carrasco B,Serrano E,Martín-González A,Moreno-Herrero F,Alonso JC

更新日期：2019-02-13 00:00:00

abstract：:Bacillus pumilus 64-1, a bacterial strain isolated from the marine sponge Plakina cyanorosea, which exhibits antimicrobial activity against both pathogenic and drug-resistant Gram-positive and Gram-negative bacteria. This study aimed to conduct an in-depth genomic analysis of this bioactive sponge-derived strain. The ...

journal_title：Frontiers in microbiology

authors： Freitas-Silva J,de Oliveira BFR,Vigoder FM,Muricy G,Dobson ADW,Laport MS

更新日期：2021-01-08 00:00:00

abstract：:Replication of the bacterial chromosome initiates at a single origin of replication that is called oriC. This occurs via the concerted action of numerous proteins, including DnaA, which acts as an initiator. The origin sequences vary across species, but all bacterial oriCs contain the information necessary to guide as...

journal_title：Frontiers in microbiology

authors： Wolański M,Donczew R,Zawilak-Pawlik A,Zakrzewska-Czerwińska J

更新日期：2015-01-06 00:00:00

abstract：:Salar de Huasco, defined as a polyextreme environment, is a high altitude saline wetland in the Chilean Altiplano (3800 m.a.s.l.), permanently exposed to the highest solar radiation doses registered in the world. We present here the first comparative proteomics study of a photoheterotrophic bacterium, Rhodobacter sp.,...

journal_title：Frontiers in microbiology

authors： Pérez V,Hengst M,Kurte L,Dorador C,Jeffrey WH,Wattiez R,Molina V,Matallana-Surget S

更新日期：2017-06-26 00:00:00

abstract：:Composed of trillions of individual microbes, the human gut microbiota has adapted to the uniquely diverse environments found in the human intestine. Quickly responding to the variances in the ingested food, the microbiota interacts with the host via reciprocal biochemical signaling to coordinate the exchange of nutri...

journal_title：Frontiers in microbiology

authors： Selber-Hnatiw S,Rukundo B,Ahmadi M,Akoubi H,Al-Bizri H,Aliu AF,Ambeaghen TU,Avetisyan L,Bahar I,Baird A,Begum F,Ben Soussan H,Blondeau-Éthier V,Bordaries R,Bramwell H,Briggs A,Bui R,Carnevale M,Chancharoen M,Chevass

更新日期：2017-07-17 00:00:00

abstract：:Thawing of permafrost soils is expected to stimulate microbial decomposition and respiration of sequestered carbon. This could, in turn, increase atmospheric concentrations of greenhouse gasses, such as carbon dioxide and methane, and create a positive feedback to climate warming. Recent metagenomic studies suggest th...

journal_title：Frontiers in microbiology

authors： Coolen MJ,Orsi WD

更新日期：2015-03-16 00:00:00

abstract：:The outer potato periderm layer consists of dead suberized cells. Suberin, a protective biopolymer, is made of a polyaliphatic portion covalently linked to polyaromatic moieties. Evidence accumulates that Streptomyces scabies, the main causal agent of potato common scab, can degrade the suberin aliphatic part but its ...

journal_title：Frontiers in microbiology

authors： Khalil M,Lerat S,Beaudoin N,Beaulieu C

更新日期：2019-12-04 00:00:00

abstract：:This study aimed to investigate antimicrobial resistance and molecular epidemiology of extended-spectrum β-lactamase (ESBL)-producing Escherichia coli (E. coli) isolated from outpatients in town hospitals of Shandong province, China. Antimicrobial susceptibility of ESBL-producing E. coli was tested using the disk diff...

journal_title：Frontiers in microbiology

authors： Miao Z,Li S,Wang L,Song W,Zhou Y

更新日期：2017-01-24 00:00:00

abstract：:Since ancient times, even in today's modern world, infectious diseases cause lots of people to die. Infectious organisms, pathogens, cause diseases by physical interactions with human proteins. A thorough analysis of these interspecies interactions is required to provide insights about infection strategies of pathogen...

journal_title：Frontiers in microbiology

authors： Durmuş Tekir S,Cakir T,Ulgen KÖ

更新日期：2012-02-14 00:00:00

abstract：:Despite the importance of diversification rates in the study of prokaryote evolution, they have not been quantitatively assessed for the majority of microorganism taxa. The investigation of evolutionary patterns in prokaryotes constitutes a challenge due to a very scarce fossil record, limited morphological differenti...

journal_title：Frontiers in microbiology

authors： Sanglas A,Albarral V,Farfán M,Lorén JG,Fusté MC

更新日期：2017-02-08 00:00:00

abstract：:Antimicrobials are the most commonly prescribed drugs in the swine industry. While antimicrobials are an effective treatment for serious bacterial infections, their use has been associated with major adverse effects on health. It has been shown that antimicrobials have substantial direct and indirect impacts on the sw...

journal_title：Frontiers in microbiology

authors： Zeineldin M,Aldridge B,Lowe J

更新日期：2019-05-15 00:00:00

abstract：:Bacteria of the Vibrio genus are the most predominant infectious agents threatening marine wildlife and aquaculture. Due to the large genetic diversity of these pathogens, the molecular determinants of Vibrio virulence are only poorly understood. Furthermore, studies tend to ignore co-evolutionary interactions between...

journal_title：Frontiers in microbiology

authors： Wegner KM,Piel D,Bruto M,John U,Mao Z,Alunno-Bruscia M,Petton B,Le Roux F

更新日期：2019-09-06 00:00:00

abstract：:Carbapenems are major antibiotics reserved to human medicine. This study aimed to investigate the mechanisms of carbapenem resistance of a selection of Pseudomonas aeruginosa veterinary strains from the French network Resapath. Thirty (5.7%) imipenem and/or meropenem non-susceptible P. aeruginosa of canine (n = 24), f...

journal_title：Frontiers in microbiology

authors： Haenni M,Bour M,Châtre P,Madec JY,Plésiat P,Jeannot K

更新日期：2017-09-29 00:00:00

abstract：:We determined the in vitro susceptibility of four aminoglycosides, which are not of the 4,6-disubstituted deoxystreptamine (DOS) subclass against a collection of carbapenem-resistant Enterobacteriaceae (CRE). CRE clinical strains (n = 134) were collected from multiple hospitals in China and carried blaNDM (blaNDM-1, b...

journal_title：Frontiers in microbiology

authors： Hu Y,Liu L,Zhang X,Feng Y,Zong Z

更新日期：2017-11-17 00:00:00

abstract：:The Fic (filamentation induced by cyclic AMP) domain is a widely distributed motif with a conserved sequence of HPFx[D/E]GN[G/K]R, some of which regulate cellular activity by catalyzing the transfer of the AMP moiety from ATP to protein substrates. Some Fic proteins, including Fic-1 from the soil bacterium Pseudomonas...

journal_title：Frontiers in microbiology

authors： Lu CH,McCloskey A,Chen FR,Nakayasu ES,Zhang LQ,Luo ZQ

更新日期：2020-08-26 00:00:00

abstract：:Cyanobacteria, a group of photosynthetic prokaryotes, oscillate between day and night time metabolisms with concomitant oscillations in gene expression in response to light/dark cycles (LD). The oscillations in gene expression have been shown to sustain in constant light (LL) with a free running period of 24 h in a mo...

journal_title：Frontiers in microbiology

authors： Gaudana SB,Krishnakumar S,Alagesan S,Digmurti MG,Viswanathan GA,Chetty M,Wangikar PP

更新日期：2013-12-06 00:00:00

abstract：:High-throughput sequencing (HTS) techniques are of great value for the investigation of microbial communities, and have been extensively used to study the gut microbiome. While most studies focus on the human gut, many others have investigated insects. However, because of the rapid spread of HTS techniques, a lot of v...

journal_title：Frontiers in microbiology

authors： De Cock M,Virgilio M,Vandamme P,Augustinos A,Bourtzis K,Willems A,De Meyer M

更新日期：2019-12-13 00:00:00

abstract：:The ability of human enteric pathogens to colonize plants and use them as alternate hosts is now well established. Salmonella, similarly to phytobacteria, appears to be capable of producing the plant hormone auxin via an indole-3-pyruvate decarboxylase (IpdC), a key enzyme of the IPyA pathway. A deletion of the Salmon...

journal_title：Frontiers in microbiology

authors： Cox CE,Brandl MT,de Moraes MH,Gunasekera S,Teplitski M

更新日期：2018-01-12 00:00:00

abstract：:Research in the deep terrestrial biosphere is driven by interest in novel biodiversity and metabolisms, biogeochemical cycling, and the impact of human activities on this ecosystem. As this interest continues to grow, it is important to ensure that when subsurface investigations are proposed, materials recovered from ...

journal_title：Frontiers in microbiology

authors： Wilkins MJ,Daly RA,Mouser PJ,Trexler R,Sharma S,Cole DR,Wrighton KC,Biddle JF,Denis EH,Fredrickson JK,Kieft TL,Onstott TC,Peterson L,Pfiffner SM,Phelps TJ,Schrenk MO

更新日期：2014-09-12 00:00:00

abstract：:Besides the major nutrients, phosphorus (P) is an essential mineral for both the host animal and the porcine gut microbiota. Different strategies including phytase supplementation and more recently lactic acid (LA) are used to enhance the P availability from cereals in pig diets; however, their impact on the gut micro...

journal_title：Frontiers in microbiology

authors： Klinsoda J,Vötterl J,Zebeli Q,Metzler-Zebeli BU

更新日期：2019-10-15 00:00:00

abstract：:Microorganisms are capable of synthesizing a plethora of secondary metabolites including the long-overlooked volatile organic compounds. Little knowledge has been accumulated regarding the regulation of the biosynthesis of such mVOCs. The emission of the unique compound sodorifen of Serratia plymuthica isolates was si...

journal_title：Frontiers in microbiology

authors： Magnus N,Weise T,Piechulla B

更新日期：2017-12-19 00:00:00

abstract：:An ideal DNA polymerase for chain-terminating DNA sequencing should possess the following features: (1) incorporate dideoxy- and other modified nucleotides at an efficiency similar to that of the cognate deoxynucleotides; (2) high processivity; (3) high fidelity in the absence of proofreading/exonuclease activity; and...

journal_title：Frontiers in microbiology

authors： Zhu B

更新日期：2014-04-16 00:00:00

abstract：:Francisella tularensis is an intracellular pathogen that can cause severe disease in a wide range of mammalian hosts. Primarily residing in host macrophages, F. tularensis escapes phagosomal degradation, and replicates in the macrophage cytosol. The macrophage uses a series of pattern recognition receptors to detect c...

journal_title：Frontiers in microbiology

authors： Jones JW,Broz P,Monack DM

更新日期：2011-02-03 00:00:00

abstract：:Ecological understandings of soil bacterial community succession and assembly mechanism along elevational gradients in mountains remain not well understood. Here, by employing the high-throughput sequencing technique, we systematically examined soil bacterial diversity patterns, the driving factors, and community asse...

journal_title：Frontiers in microbiology

authors： Li J,Shen Z,Li C,Kou Y,Wang Y,Tu B,Zhang S,Li X

更新日期：2018-03-27 00:00:00

abstract：:A nitrate- and metal-contaminated site at the Oak Ridge Reservation (ORR) was previously shown to contain the metal molybdenum (Mo) at picomolar concentrations. This potentially limits microbial nitrate reduction, as Mo is required by the enzyme nitrate reductase, which catalyzes the first step of nitrate removal. Enr...

journal_title：Frontiers in microbiology

authors： Ge X,Thorgersen MP,Poole FL 2nd,Deutschbauer AM,Chandonia JM,Novichkov PS,Gushgari-Doyle S,Lui LM,Nielsen T,Chakraborty R,Adams PD,Arkin AP,Hazen TC,Adams MWW

更新日期：2020-10-19 00:00:00