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Antithrombotics: From Aspirin to DOACs in Coronary Artery Disease and Atrial Fibrillation (Part 3/5).

Abstract：

:For secondary prevention of coronary artery disease (CAD), oral antiplatelet therapy is essential. In case of coronary intervention, temporary dual antiplatelet therapy is mandatory as well. Recently, low-dose oral anticoagulation has entered the CAD arena. Atrial fibrillation (AF) is often seen in CAD and vice versa. In most patients stroke prevention in AF consists of oral anticoagulation. In many cases of CAD in patients with AF, anticoagulation has to be combined with antiplatelet agents (so called, dual pathway antithrombotic therapy). Excess bleeding in these conditions is a rapidly rising problem. This review addresses the antithrombotic options in CAD alone, in AF alone, and in their combination, when either an invasive or a noninvasive approach has been chosen.

journal_name

J Am Coll Cardiol

journal_title

Journal of the American College of Cardiology

authors

Verheugt FWA,Ten Berg JM,Storey RF,Cuisset T,Granger CB

doi

10.1016/j.jacc.2019.02.080

subject

Has Abstract

pub_date

2019-08-06 00:00:00

pages

699-711

issue

5

eissn

0735-1097

issn

1558-3597

pii

S0735-1097(19)35400-2

journal_volume

74

pub_type

杂志文章,评审

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