Myeloid zinc finger-1 regulates expression of cancer-associated fibroblast and cancer stemness profiles in breast cancer.

abstract：:No new chemotherapy agents have been developed recently that present hope for improving survival in patients with colon or rectal cancer. We undertook this study to investigate a new route of administering an old drug, 5-fluorouracil (5-FU). Sixty-six patients with advanced primary colon or rectal cancer were randomiz...

journal_title：Surgery

authors： Sugarbaker PH,Gianola FJ,Speyer JC,Wesley R,Barofsky I,Meyers CE

更新日期：1985-09-01 00:00:00

abstract：PURPOSE:The purpose of this study was to evaluate whether ultrasonography is helpful in predicting malignancy in patients with a thyroid nodule and atypia/follicular lesion of undetermined significance (AFLUS). METHODS:All patients with a preoperative ultrasound who underwent thyroidectomy for a nodule with AFLUS comp...

journal_title：Surgery

authors： Khoncarly SM,Tamarkin SW,McHenry CR

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:Papillary thyroid microcarcinomas (PTMCs), located at upper poles of the thyroid, are associated with lateral neck metastasis (LNM) according to previous reports. Controversy remains regarding the correlation between the location of PTMCs and central neck metastasis (CNM). METHODS:Medical records of 949 pat...

journal_title：Surgery

authors： Xiang D,Xie L,Xu Y,Li Z,Hong Y,Wang P

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND:Routine and radical lymph node dissection is a clinical concern for improving the surgical outcome in patients with intrahepatic cholangiocarcinoma (ICC). The therapeutic value of the procedure during hepatectomy has, however, not been evaluated. METHODS:Between January 1990 and December 2004, 104 patients ...

journal_title：Surgery

authors： Shimada K,Sano T,Nara S,Esaki M,Sakamoto Y,Kosuge T,Ojima H

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND:Classic surgical treatment of upper third gastric carcinoma is based on an extended total gastrectomy, including splenectomy. The purpose of this study was to perform a prospective randomized clinical trial comparing the early and late results of total gastrectomy (TG) versus total gastrectomy plus splenecto...

journal_title：Surgery

authors： Csendes A,Burdiles P,Rojas J,Braghetto I,Diaz JC,Maluenda F

更新日期：2002-04-01 00:00:00

abstract：BACKGROUND:In an attempt to prevent overly aggressive treatment of low-risk thyroid cancers, the American Thyroid Association changed guideline recommendations in late 2015 to state that either hemithyroidectomy or total thyroidectomy are acceptable operations for these patients. We hypothesized that surgeons would inc...

journal_title：Surgery

authors： Ullmann TM,Gray KD,Stefanova D,Limberg J,Buicko JL,Finnerty B,Zarnegar R,Fahey TJ 3rd,Beninato T

更新日期：2019-09-01 00:00:00

abstract：:Arteriosclerotic aneurysm of the innominate artery is an unusual lesion. A review of the literature has revealed many approaches to this problem in the past, but the mortality rate has remained significant and serious complications have been frequent. Computerized axial tomography and noninvasive cerebrovascular metho...

journal_title：Surgery

authors： Schumacher PD,Wright CB

更新日期：1979-05-01 00:00:00

abstract：:Lymphocytes from melanoma patients more frequently inhibited the growth of human melanoma cells in the hamster cheek pouch than did lymphocytes from normal donors. Growth inhibition was accomplished with a much lower ratio of target cells to lymphocytes than in in vitro assays. The hamster cheek pouch assay can be use...

journal_title：Surgery

authors： Richmond RE,Townsend CM Jr,Morton DL

更新日期：1977-03-01 00:00:00

abstract：:The incidence of fascial disruption after major abdominal operations is 1% to 3%, and dehiscence is associated with a mortality rate of 15% to 20%. Although several systemic factors (e.g., malnutrition, increased age, male sex, and chronic treatment with steroids) have been associated with an increased risk of wound d...

journal_title：Surgery

authors： Poole GV Jr

更新日期：1985-06-01 00:00:00

abstract：BACKGROUND:In 2009, a study from our institution used retrospective data and multivariate analysis to identify 5 quantitative variables and their cutoffs that have a positive predictive value (PPV) for common bile duct (CBD) stones in gallstone pancreatitis. They also proposed a management protocol based on the scoring...

journal_title：Surgery

authors： Sherman JL,Shi EW,Ranasinghe NE,Sivasankaran MT,Prigoff JG,Divino CM

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:The management of splenic injuries has evolved with a greater emphasis on nonoperative management. Although several institutions have demonstrated that nonoperative management of splenic injuries can be performed with an increasing degree of success, the impact of this treatment shift on outcome for all pati...

journal_title：Surgery

authors： Harbrecht BG,Zenati MS,Ochoa JB,Puyana JC,Alarcon LH,Peitzman AB

更新日期：2007-02-01 00:00:00

abstract：:The effect of somatostatin analogue SMS 201-995 on pancreatic blood flow was studied. In 24 dogs all vessels to the pancreas, except for the pancreaticoduodenal artery and vein, were divided. A flow probe was placed around the pancreaticoduodenal artery. The animals were divided into four groups. Control animals recei...

journal_title：Surgery

authors： Conway DR,Djuricin G,Prinz RA

更新日期：1988-12-01 00:00:00

abstract：BACKGROUND:The number of dendritic cells (DC) in the local tumor environment correlates with patient survival in numerous tumors. The relationship of DC infiltration in the tumor microenvironment and prognosis was examined in patients with pancreatic adenocarcinoma. METHODS:Forty-seven pancreatectomy specimens with a ...

journal_title：Surgery

authors： Dallal RM,Christakos P,Lee K,Egawa S,Son YI,Lotze MT

更新日期：2002-02-01 00:00:00

abstract：BACKGROUND:The glial cell line-derived neurotrophic factor (GDNF) is a member of neurotrophic polypeptide family, which promotes survival and rescue of various neural cells in the central and peripheral nerve systems. We previously reported that GDNF promotes tumor cell invasion in pancreatic cancer cell lines. The pur...

journal_title：Surgery

authors： Ito Y,Okada Y,Sato M,Sawai H,Funahashi H,Murase T,Hayakawa T,Manabe T

更新日期：2005-10-01 00:00:00

abstract：:Advances in radiation techniques and increased dosage have improved the cure rate of patients with cancer of the cervix to 65 percent. Associated with this increased dosage (betatron, 5,250 r and intracavitary 137-cesium, 4,000 r at point A) has been a serious complication incidence of 10 percent. Major intestinal com...

journal_title：Surgery

authors： Palmer JA,Bush RS

更新日期：1976-10-01 00:00:00

abstract：BACKGROUND:The Lombardy region suffered severely during the acute phase of the coronavirus disease 2019 outbreak in Italy (Mar-Apr 2020) with 16,000 diagnosed coronavirus disease 2019-related deaths (49% of the total coronavirus disease 2019-related deaths in Italy). In the area surrounding Pavia during the critical st...

journal_title：Surgery

authors： Bozzani A,Arici V,Tavazzi G,Franciscone MM,Danesino V,Rota M,Rossini R,Sterpetti AV,Ticozzelli G,Rumi E,Mojoli F,Bruno R,Ragni F

更新日期：2020-12-01 00:00:00

abstract：:Two patient groups were studied to determine the need to preserve the greater saphenous vein during femoral outflow reconstruction for later aortocoronary bypass procedures. First, 74 patients were followed to the time of death or to a minimum of 5 years after femoral outflow reconstruction was performed. Only four pa...

journal_title：Surgery

authors： Houser SL,Hashmi FH,Jaeger VJ,Chawla SK,Brown L,Kemler RL

更新日期：1984-04-01 00:00:00

abstract：BACKGROUND:Since November 1992, operative repair in neonates with congenital diaphragmatic hernia (CDH) at this institution was delayed until respiratory insufficiency had resolved. METHODS:A retrospective analysis was performed (n = 33) comparing delayed repair with our previously reported institutional experience wi...

journal_title：Surgery

authors： Reickert CA,Hirschl RB,Schumacher R,Geiger JD,Cox C,Teitelbaum DH,Polley TZ Jr,Harmon CM,Lelli JL,Coran AG

更新日期：1996-10-01 00:00:00

abstract：:Metabolic alkalosis secondary to chloride depletion, especially following gastrointestinal surgery and associated with acute renal failure, is a frequent clinical occurrence. Management of the resultant acid-base disturbance mandates chloride replacement. The presence of oliguria limits the choice of accompanying cati...

journal_title：Surgery

authors： Shavelle HS,Parke R

更新日期：1975-10-01 00:00:00

abstract：BACKGROUND:Cyclosporine causes intrarenal vasoconstriction, which may account for its nephrotoxic side effects. Plasma levels of the vasoconstrictor peptide endothelin-1 are increased after cyclosporine administration, and endothelin-1 has been shown to cause renal vasoconstriction. In this study we used in vivo micros...

journal_title：Surgery

authors： Bloom IT,Bentley FR,Garrison RN

更新日期：1993-08-01 00:00:00

abstract：:A patient's condition was initially diagnosed as constrictive pericarditis, but an echocardiogram revealed the presence of an intracardiac tumor. The tumor was a slow-growing leiomyosarcoma that originated in the left internal iliac vein, extended into the inferior vena cava, and reached the right ventricle. This tumo...

journal_title：Surgery

authors： Kaku K,Kawashima Y,Kitamura S,Nakano S,Mori T,Beppu SU,Kozuka T,Sakurai M,Katayama S,Tanizawa O,Sonoda T

更新日期：1981-05-01 00:00:00

abstract：:The shear stress resistance of cultured human endothelium was investigated on 6 mm polytetrafluoroethylene vascular grafts. Endothelial cell attachment was promoted by precoating the grafts with fibrin glue, which contained human fibronectin and inhibitors of fibrinolysis (aprotinin and tranexam acid). To evaluate the...

journal_title：Surgery

authors： Zilla P,Fasol R,Preiss P,Kadletz M,Deutsch M,Schima H,Tsangaris S,Groscurth P

更新日期：1989-04-01 00:00:00

abstract：BACKGROUND:Although the price hospitals charge for operations has broad financial implications, hospital pricing is not subject to regulation. We sought to characterize national variation in hospital price markup for major cardiothoracic and gastrointestinal operations and to evaluate perioperative outcomes of hospital...

journal_title：Surgery

authors： Gani F,Ejaz A,Makary MA,Pawlik TM

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:While roughly half of adrenocortical carcinomas are functional, whether functional status impacts outcomes remains controversial. We compared presentation and survival for functional and nonfunctional neoplasms. METHODS:Adult patients presented with adrenocortical carcinomas at the Mayo Clinic were included...

journal_title：Surgery

authors： Sada A,Asaad M,Bews KA,Thompson GB,Young WF Jr,Bancos I,Farley DR,Dy BM,Lyden ML,Habermann EB,McKenzie TJ

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Cell migration is an integral part of the development of intimal hyperplasia, and proteases are pivotal components in the process. Cell migration in response to urokinase is mediated through the aminoterminal fragment (ATF) of the protein. This study examines the role of NAD(P)H oxidase during epidermal grow...

journal_title：Surgery

authors： Duru EA,Fu Y,Davies MG

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:Although preoperative administration of high-dose glucocorticoid may lead to improved recovery after operative procedures, this regimen has not been examined in patients undergoing abdominal wall reconstruction for repair of large ventral hernias. The aim of the current trial was to examine the effects of pr...

journal_title：Surgery

authors： Jensen KK,Brøndum TL,Leerhøy B,Belhage B,Hensler M,Arnesen RB,Kehlet H,Jørgensen LN

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:Neuroendocrine tumors (NETs) are a potentially lethal component of multiple endocrine neoplasia type 1 (MEN 1). Somatostatin receptor scintigraphy (SRS) can be used to localize NETs and evaluate patients for extraduodenopancreatic disease; its utility in managing MEN 1 is undefined. METHODS:All patients wit...

journal_title：Surgery

authors： Yim JH,Siegel BA,DeBenedetti MK,Norton JA,Lairmore TC,Doherty GM

更新日期：1998-12-01 00:00:00

abstract：:Diffuse compensatory extramedullary hematopoiesis is well known to involve the spleen and liver in certain hematologic disorders. Hematopoietic tumor masses occasionally form and usually occur paraspinally in the posterior mediastinum. A 31-year-old patient with thalassemia is described with a massive, solitary, intra...

journal_title：Surgery

authors： Dewar G,Leung NW,Ng HK,Bradley M,Li AK

更新日期：1990-06-01 00:00:00

abstract：BACKGROUND:We have previously shown minimal evidence of neutrophil infiltration during early reperfusion of porcine ischemic ileum. However, we noted marked neutrophil infiltration 6 to 18 hours after ischemia during mucosal repair. We postulated such neutrophil infiltration would disrupt restituting epithelium. METHO...

journal_title：Surgery

authors： Gayle J,Jones SL,Argenzio RA,Blikslager AT

更新日期：2002-09-01 00:00:00

abstract：BACKGROUND:Parathyroidectomy has a success rate of greater than 95% in the hands of experienced surgeons. To maintain this result in a more cost-effective way, intraoperative monitoring of intact parathyroid hormone (iPTH) has been used to decrease operative times. This technique signals when all hyperfunctioning tissu...

journal_title：Surgery

authors： Boggs JE,Irvin GL 3rd,Molinari AS,Deriso GT

更新日期：1996-12-01 00:00:00