Abstract:
:Allospecific suppressor T cells can be generated by allostimulating thymus, spleen and lymph node cells in culture. Bone marrow cells do not yield suppressor lymphocytes. While the efficiency of thymocytes for suppressor cell generation decreases with the age of thymus donors, the efficiency of spleen increases with age. Generation of suppressor lymphocytes depends on cell replication and protein synthesis. The suppressor function as such does not require cell replication. Induction of suppressor T cells in culture requires cell to cell interaction of cortical type and medullar type T cells.
journal_name
Adv Exp Med Bioljournal_title
Advances in experimental medicine and biologyauthors
Eisenthal A,Nachtigal D,Feldman Mdoi
10.1007/978-1-4615-9101-6_48subject
Has Abstractpub_date
1979-01-01 00:00:00pages
301-6eissn
0065-2598issn
2214-8019journal_volume
114pub_type
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journal_title:Advances in experimental medicine and biology
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