Abstract:
:PAF stimulation of NF-kappa B activation and transcription of immediate-early genes have been investigated in peripheral blood mononuclear cells and in transfected Chinese hamster ovary cells expressing the cloned PAF receptor. These studies identified a G protein-coupled pathway for PAF induction of gene expression and transcription factor activation, which differs from the mechanisms employed by other immediate-early gene inducers. Potential significance of PAF induced NF-kappa B activation is discussed.
journal_name
Adv Exp Med Bioljournal_title
Advances in experimental medicine and biologyauthors
Ye RD,Kravchenko VV,Pan Z,Feng Ldoi
10.1007/978-1-4899-0179-8_24subject
Has Abstractpub_date
1996-01-01 00:00:00pages
143-51eissn
0065-2598issn
2214-8019journal_volume
416pub_type
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