A rare case of transformation of childhood myelodysplastic syndrome to acute lymphoblastic leukemia.

abstract：BACKGROUND:Multiple-locus variable-number tandem-repeat fingerprinting (MLVF) is based on multiplex PCR, utilizing variable number tandem repeat. Our goal was to compare the performance of MLVF in distinguishing clinical Staphylococcus aureus isolates with that of pulsed-field gel electrophoresis (PFGE), which has trad...

journal_title：Annals of laboratory medicine

authors： Chung S,Yi J,Jang MH,Joo SI,Ra EK,Kim SY,Chang CL,Park SS,Kim EC

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:The identification of molds in clinical laboratories is largely on the basis of phenotypic criteria, the classification of which can be subjective. Recently, molecular methods have been introduced for identification of pathogenic molds in clinical settings. Here, we employed comparative sequence analysis to ...

journal_title：Annals of laboratory medicine

authors： Jang JH,Lee JH,Ki CS,Lee NY

更新日期：2012-03-01 00:00:00

abstract：:The most common recurrent cytogenetic abnormalities in T-lymphoblastic leukemia (T-acute lymphoblastic leukemia [T-ALL]) involve T-cell receptor (TCR) loci and a variety of partner genes, including HOX11, HOX11L2, MYC, and TAL1. In this report, we present a rare case involving simultaneous translocation of the TCR α/δ...

journal_title：Annals of laboratory medicine

authors： Kang DH,Kim SH,Jun JW,Lee YW,Shin HB,Ahn JY,Hong DS,Lee YK,Jeon BR

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:Validation of hemagglutination inhibition (HI) assays is important for evaluating antibody responses to influenza virus, and selection of erythrocytes for use in these assays is important. This study aimed to determine the correlation between receptor binding specificity and effectiveness of the HI assay for...

journal_title：Annals of laboratory medicine

authors： Makkoch J,Prachayangprecha S,Payungporn S,Chieochansin T,Songserm T,Amonsin A,Poovorawan Y

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:Major burn injury induces an inflammatory response that is accompanied by the release of various cytokines. We investigated the gradual changes in the levels of pro-inflammatory and anti-inflammatory cytokines following burn injury and determined the relationship between these levels and burn size in adult K...

journal_title：Annals of laboratory medicine

authors： Kim HS,Kim JH,Yim H,Kim D

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:We compared the LightCycler MRSA advanced test (Roche Diagnostics, Germany) with enrichment culture methods to evaluate the relative diagnostic performance of the LightCycler MRSA advanced test for active surveillance in a high-prevalence setting. METHODS:A total of 342 nasal swab specimens were obtained fr...

journal_title：Annals of laboratory medicine

authors： Huh HJ,Kim ES,Chae SL

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:The primary purpose of this study was to investigate the prevalence and characteristics of p16 methylation and determine the prognostic implications of the clinical data, hematologic data, and p16 methylation changes in plasma cell myeloma (PCM). METHODS:We reviewed clinical characteristics and results of l...

journal_title：Annals of laboratory medicine

authors： Kim H,Jekarl DW,Kim M,Kim Y,Lim J,Han K,Min CK

更新日期：2013-01-01 00:00:00

abstract：:Three automated immunoassay kits for anti-Hepatitis A Virus (HAV) IgM-Architect, (Abbott Laboratories, USA), Elecsys (Roche Diagnostics, Germany), and ADVIA Centaur (Siemens Healthcare Diagnostics Inc., USA)-were compared. We included 178 consecutive samples, for which an anti-HAV IgM test was requested at Seoul Natio...

journal_title：Annals of laboratory medicine

authors： Park H,Lee YJ,Seong MW,Lee DH,Park MH,Song EY

更新日期：2013-03-01 00:00:00

abstract：:We report a case of CTX-M-55-type extended-spectrum β-lactamase (ESBL)-producing Shigella sonnei infection in a 27-year-old Korean woman who had traveled to China. The patient was admitted to the hospital due to abdominal pain, watery diarrhea, and fever (39.3℃). S. sonnei was isolated from her stool specimens, and th...

journal_title：Annals of laboratory medicine

authors： Lee W,Chung HS,Lee H,Yum JH,Yong D,Jeong SH,Lee K,Chong Y

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:The prognostic impact of the presence of differentiating neuroblasts in bone marrow (BM) remains unclear in BM metastatic neuroblastoma (NB). We aimed to identify the prognostic impact of differentiating neuroblasts in BM at diagnosis and after chemotherapy. METHODS:A total of 51 patients diagnosed with BM ...

journal_title：Annals of laboratory medicine

authors： Park SH,Kim S,Park CJ,Jang S,Chi HS,Koh KN,Im HJ,Seo JJ

更新日期：2013-03-01 00:00:00

abstract：:Nocardia pseudobrasiliensis is predominantly associated with invasive infections in immunocompromised patients. We report a case of disseminated mycetoma caused by N. pseudobrasiliensis in a 57-yr-old woman with microscopic polyangiitis, who was treated for 3 months with corticosteroids. The same organism was isolated...

journal_title：Annals of laboratory medicine

authors： Seol CA,Sung H,Kim DH,Ji M,Chong YP,Kim MN

更新日期：2013-05-01 00:00:00

abstract：BACKGROUND:The aims of this study were to understand the molecular epidemiology of integron-associated gene cassettes in Acinetobacter baumannii across four hospitals in northern Taiwan and to clarify the relationship between the presence of integrons and antibiotic-resistant phenotypes. METHODS:Sixty-five A. baumanni...

journal_title：Annals of laboratory medicine

authors： Lin MF,Liou ML,Tu CC,Yeh HW,Lan CY

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:This study aimed to evaluate the prevalence of Mycoplasma pneumoniae in primary and tertiary care hospitals and its macrolide resistance rate. METHODS:Nasopharyngeal swabs were collected from 195 pediatric patients in primary and tertiary care hospitals from October to November 2010. The AccuPower MP real-t...

journal_title：Annals of laboratory medicine

authors： Uh Y,Hong JH,Oh KJ,Cho HM,Park SD,Kim J,Yoon KJ

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:Busulfan, an alkylating agent administered prior to hematopoietic stem cell transplantation, has a narrow therapeutic range and wide variability in metabolism. We developed a liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for rapid and accurate quantification of plasma busulfan. METHODS:Bu...

journal_title：Annals of laboratory medicine

authors： Moon SY,Lim MK,Hong S,Jeon Y,Han M,Song SH,Lim KS,Yu KS,Jang IJ,Lee JW,Kang HJ,Song J

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Atelosteogenesis type I (AO-I) is a rare lethal skeletal dysplastic disorder characterized by severe short-limbed dwarfism and dislocated hips, knees, and elbows. AO-I is caused by mutations in the filamin B (FLNB) gene; however, several other genes can cause AO-like lethal skeletal dysplasias. METHODS:In o...

journal_title：Annals of laboratory medicine

authors： Jeon GW,Lee MN,Jung JM,Hong SY,Kim YN,Sin JB,Ki CS

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:We evaluated the analytical and clinical performances of the SD BIOLINE Rota/Adeno Rapid kit (SD Rota/Adeno Rapid; Standard Diagnostics, Inc., Korea), an immunochromatographic assay (ICA), for the simultaneous detection of rotaviruses and adenoviruses in human stool samples. METHODS:We tested 400 clinical s...

journal_title：Annals of laboratory medicine

authors： Kim J,Kim HS,Kim HS,Kim JS,Song W,Lee KM,Lee S,Park KU,Lee W,Hong YJ

更新日期：2014-05-01 00:00:00

abstract：:Laboratories working towards accreditation by the International Standards Organization (ISO) 15189 standard are required to demonstrate the validity of their analytical methods. The different guidelines set by various accreditation organizations make it difficult to provide objective evidence that an in-house method i...

journal_title：Annals of laboratory medicine

authors： Garcia Hejl C,Ramirez JM,Vest P,Chianea D,Renard C

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:Antimicrobial susceptibility testing (AST) of Clostridium difficile is increasingly important because of the rise in resistant strains. The standard medium for the AST of C. difficile is supplemented Brucella agar (sBA), but we found that the growth of C. difficile on sBA was not optimal. Because active grow...

journal_title：Annals of laboratory medicine

authors： Kim GH,Kim J,Pai H,Kang JO

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND:We developed an analytical method to measure α-L-iduronidase (IDUA) activity in dried blood spots. This was achieved by using liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS) with electrospray ionization in the positive ion mode. METHODS:Chromatographic separation was completed using mob...

journal_title：Annals of laboratory medicine

authors： Yang JS,Min HK,Oh HJ,Woo HI,Lee SY,Kim JW,Song J,Park HD

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Major burn injuries induce inflammatory responses and changes in the levels of various cytokines. This study was conducted to assess early changes in the serum levels of inflammatory cytokines after burn injury, identify cytokines associated with mortality, and characterize correlations among cytokines. MET...

journal_title：Annals of laboratory medicine

authors： Hur J,Yang HT,Chun W,Kim JH,Shin SH,Kang HJ,Kim HS

更新日期：2015-01-01 00:00:00

abstract：:[This corrects the article on p. 219 in vol. 31.]. ...

journal_title：Annals of laboratory medicine

authors：

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Bone marrow biopsies are routinely performed for staging patients with B-cell non-Hodgkin lymphoma (NHL). In addition to histomorphological studies, ancillary tools may be needed for accurate diagnosis. We investigated the clinical utility of multiparameter flow cytometric examination of bone marrow aspirate...

journal_title：Annals of laboratory medicine

authors： Kim B,Lee ST,Kim HJ,Kim SH

更新日期：2015-03-01 00:00:00

abstract：:Emerging resistance to trimethoprim/sulfamethoxazole (SXT) poses a serious threat to the treatment of Stenotrophomonas maltophilia infections. We determined the prevalence and molecular characteristics of acquired SXT resistance in recent clinical S. maltophilia isolates obtained from Korea. A total of 252 clinical is...

journal_title：Annals of laboratory medicine

authors： Chung HS,Kim K,Hong SS,Hong SG,Lee K,Chong Y

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND:Angiotensin II type 1 receptor (AT1R) is responsible for cardiovascular effects mediated by angiotensin II. This study aimed to investigate the impact of antibodies directed against AT1R (anti-AT1R) in renal allograft rejection. METHODS:We evaluated 53 patients who had biopsy-proven rejection including anti...

journal_title：Annals of laboratory medicine

authors： Lee H,Kim JI,Moon IS,Chung BH,Yang CW,Kim Y,Han K,Oh EJ

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND:This study describes a novel analytical method for simultaneously determining sarpogrelate and its metabolite (M-1) in human plasma, using liquid chromatography coupled with tandem mass spectrometry, with electrospray ionization in the positive ion mode. METHODS:Sarpogrelate, M-1, and labeled internal stand...

journal_title：Annals of laboratory medicine

authors： Yang JS,Kim JR,Cho E,Huh W,Ko JW,Lee SY

更新日期：2015-07-01 00:00:00

abstract：:Staphylococcus aureus bacteremia is associated with high mortality and morbidity, requiring prompt and appropriate antimicrobial treatment. Therefore, it is important to detect methicillin-resistant S. aureus (MRSA) rapidly from blood cultures. Two immunochromatographic tests, BinaxNow S. aureus and BinaxNow PBP2a, we...

journal_title：Annals of laboratory medicine

authors： Heraud S,Freydiere AM,Doleans-Jordheim A,Bes M,Tristan A,Vandenesch F,Laurent F,Dauwalder O

更新日期：2015-07-01 00:00:00

abstract：:High-resolution imaging techniques have increased the detection rate of adrenal incidentaloma. We developed a method of liquid chromatography-tandem mass spectrometry (LC-MS/MS) for detection of plasma free metanephrine (MN) and normetanephrine (NMN) and evaluated its analytical performance and clinical efficacy in di...

journal_title：Annals of laboratory medicine

authors： Lee SM,Lee MN,Oh HJ,Cho YY,Kim JH,Woo HI,Park HD,Lee SY

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND:Anti-Gal is a major antibody induced in non-human primates (NHPs) after xenotransplantation. To understand the mechanism of graft rejection, we investigated the association between anti-Gal responses and graft failure in NHP recipients of porcine islet transplantation (PITx). METHODS:Intraportal PITx was pe...

journal_title：Annals of laboratory medicine

authors： Kang HJ,Lee H,Park EM,Kim JM,Shin JS,Kim JS,Park CG,Kim SJ

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:Recent advances in laboratory information systems have largely been focused on automation. However, the phlebotomy services have not been completely automated. To address this issue, we introduced an automated reception and turnaround time (TAT) management system, for the first time in Korea, whereby the pat...

journal_title：Annals of laboratory medicine

authors： Yun SG,Shin JW,Park ES,Bang HI,Kang JG

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Acinetobacter baumannii infections are difficult to treat owing to the emergence of various antibiotic resistant isolates. Because treatment options are limited for multidrug-resistant (MDR) A. baumannii infection, the discovery of new therapies, including combination therapy, is required. We evaluated the s...

journal_title：Annals of laboratory medicine

authors： Park GC,Choi JA,Jang SJ,Jeong SH,Kim CM,Choi IS,Kang SH,Park G,Moon DS

更新日期：2016-03-01 00:00:00