Endogenous CRISPR-Cas System-Based Genome Editing and Antimicrobials: Review and Prospects.

abstract：:The term microbiome describes the genetic material encoding the various microbial populations that inhabit our body. Whilst colonization of various body niches (e.g., the gut) by dynamic communities of microorganisms is now universally accepted, the existence of microbial populations in other "classically sterile" loc...

journal_title：Frontiers in microbiology

authors： Whittle E,Leonard MO,Harrison R,Gant TW,Tonge DP

更新日期：2019-01-17 00:00:00

abstract：:The marine bacterium Microbulbifer sp. A4B-17 produces secondary metabolites such as 4-hydroxybenzoic acid (4HBA) and esters of 4HBA (parabens). 4HBA is a useful material in the synthesis of the liquid crystal. Parabens are man-made compounds that have been extensively used since the 1920s in the cosmetic, pharmaceuti...

journal_title：Frontiers in microbiology

authors： Tian J,Zhu L,Wang W,Zhang L,Li Z,Zhao Q,Xing K,Feng Z,Peng X

更新日期：2018-12-18 00:00:00

abstract：:The growing human population is currently facing an unprecedented challenge regarding global food sustainability. Thus, it is of paramount to maintain food production and quality while avoiding a negative impact on climate change and the environment at large. Along the food chain, several practices could compromise fu...

journal_title：Frontiers in microbiology

authors： Gutiérrez D,Fernández L,Rodríguez A,García P

更新日期：2019-01-22 00:00:00

abstract：:Autoimmune diseases are increasingly linked to aberrant gut microbiome and relevant metabolites. However, the association between vitiligo and the gut microbiome remains to be elucidated. Thus, we conducted a case-control study through 16S rRNA sequencing and serum untargeted-metabolomic profiling based on 30 vitiligo...

journal_title：Frontiers in microbiology

authors： Ni Q,Ye Z,Wang Y,Chen J,Zhang W,Ma C,Li K,Liu Y,Liu L,Han Z,Gao T,Jian Z,Li S,Li C

更新日期：2020-12-14 00:00:00

abstract：:From 2015 onwards, the number of vancomycin-resistant Enterococcus faecium (VREfm) isolates increased in Tasmania. Previously, we examined the transmission of VREfm at the Royal Hobart Hospital (RHH). In this study, we performed a state-wide analysis of VREfm from Tasmania's four public acute hospitals. Whole-genome a...

journal_title：Frontiers in microbiology

authors： Leong KWC,Kalukottege R,Cooley LA,Anderson TL,Wells A,Langford E,O'Toole RF

更新日期：2020-01-15 00:00:00

abstract：:The present study was designed to clarify the taxonomic status of two species classified as Bacillus cereus sensu lato, namely B. cereus sensu stricto and Bacillus thuringiensis. To this end, nearly 900 whole genome sequences of strains assigned to these taxa were the subject of comparative genomic and phylogenomic an...

journal_title：Frontiers in microbiology

authors： Baek I,Lee K,Goodfellow M,Chun J

更新日期：2019-08-23 00:00:00

abstract：:A rich variety of indigenous fruits and vegetables grow in Africa, which contribute to the nutrition and health of Africa's populations. Fruits and vegetables have high moisture and are thus inherently prone to accelerated spoilage. Food fermentation still plays a major role in combating food spoilage and foodborne di...

journal_title：Frontiers in microbiology

authors： Oguntoyinbo FA,Fusco V,Cho GS,Kabisch J,Neve H,Bockelmann W,Huch M,Frommherz L,Trierweiler B,Becker B,Benomar N,Gálvez A,Abriouel H,Holzapfel WH,Franz CM

更新日期：2016-07-05 00:00:00

abstract：:Host population density is positively associated with the strength of social interactions or the frequency of physical contacts, and thus potentially influences microbial transmission among individuals. However, the relationship between host density and gut microbiota remains unknown. Here, we characterized the gut mi...

journal_title：Frontiers in microbiology

authors： Li H,Qu J,Li T,Li J,Lin Q,Li X

更新日期：2016-05-18 00:00:00

abstract：:Long non-coding RNAs (lncRNAs) regulate gene expression at the epigenetic, transcriptional, or posttranscriptional level by interacting with protein, DNA, and RNA. Emerging evidence suggests that various lncRNAs are abnormally expressed and play indispensable roles in virus-triggered cancers. Besides, a growing number...

journal_title：Frontiers in microbiology

authors： Liu W,Zhang Y,Luo B

更新日期：2021-01-15 00:00:00

abstract：:Salmonella has emerged as a well-recognized food-borne pathogen, with many strains able to form biofilms and thus cause cross-contamination in food processing environments where acid-based disinfectants are widely encountered. In the present study, RNA sequencing was employed to establish complete transcriptome profil...

journal_title：Frontiers in microbiology

authors： Jia K,Wang G,Liang L,Wang M,Wang H,Xu X

更新日期：2017-09-26 00:00:00

abstract：:A microbiome is defined as a complex collection of microorganisms and their genetic material. Studies regarding gut microbiomes of different animals have provided ecological and evolutionary information showing a strong link between health and disease. Very few studies have compared the gut microbiota of animals house...

journal_title：Frontiers in microbiology

authors： Sandri C,Correa F,Spiezio C,Trevisi P,Luise D,Modesto M,Remy S,Muzungaile MM,Checcucci A,Zaborra CA,Mattarelli P

更新日期：2020-10-20 00:00:00

abstract：:Infections by methicillin-resistant Staphylococcus aureus (MRSA) are gradually increasing in the community. In this study, we investigated a total of 162 food samples including 112 ready-to-eat (RTE) foods and 40 processed raw meat and fish samples collected from retail vendors in Dhaka, Bangladesh and determined the ...

journal_title：Frontiers in microbiology

authors： Islam MA,Parveen S,Rahman M,Huq M,Nabi A,Khan ZUM,Ahmed N,Wagenaar JA

更新日期：2019-03-14 00:00:00

abstract：:The biocontrol fungus Trichoderma longibrachiatum SMF2 secretes a large quantity of peptaibols that have been shown to have a range of biological activities and therefore great application values. However, the mechanism of the regulatory expression of peptaibols is still unclear. The putative methyltransferase LaeA/LA...

journal_title：Frontiers in microbiology

authors： Shi JC,Shi WL,Zhou YR,Chen XL,Zhang YZ,Zhang X,Zhang WX,Song XY

更新日期：2020-06-12 00:00:00

abstract：:Biological nitrogen fixation plays a crucial role in the nitrogen cycle. An ability to fix atmospheric nitrogen, reducing it to ammonium, was described for multiple species of Bacteria and Archaea. The transcriptional regulatory network for nitrogen fixation was extensively studied in several representatives of the cl...

journal_title：Frontiers in microbiology

authors： Tsoy OV,Ravcheev DA,Čuklina J,Gelfand MS

更新日期：2016-08-26 00:00:00

abstract：:In this study, we have explored the impact of ascorbic acid on the transcriptome of Streptococcus pneumoniae D39. The expression of several genes and operons, including the ula operon (which has been previously shown to be involved in ascorbic acid utilization), the AdcR regulon (which has been previously shown to be ...

journal_title：Frontiers in microbiology

authors： Afzal M,Shafeeq S,Kuipers OP

更新日期：2015-02-11 00:00:00

abstract：:The role of food in human exposure to antimicrobial-resistant bacteria is a growing food safety issue. The contribution of fruits and vegetables eaten raw to this exposure is still unclear. The evaluation of contamination levels of fruits, vegetables and the agricultural environment by third-generation cephalosporin (...

journal_title：Frontiers in microbiology

authors： Mesbah Zekar F,Granier SA,Marault M,Yaici L,Gassilloud B,Manceau C,Touati A,Millemann Y

更新日期：2017-08-24 00:00:00

abstract：:Bacterial biofilms have an impact in medical and industrial environments because they often confer protection to bacteria against harmful agents, and constitute a source from which microorganisms can disperse. Conjugative plasmids can enhance bacterial ability to form biofilms because conjugative pili act as adhesion ...

journal_title：Frontiers in microbiology

authors： Gama JA,Fredheim EGA,Cléon F,Reis AM,Zilhão R,Dionisio F

更新日期：2020-08-26 00:00:00

abstract：:Methane and methanol are common industrial by-products that can be used as feedstocks for the production of value-added products by methylotrophic bacteria. Alphaproteobacterial methanotrophs are known to produce and accumulate the biopolymer polyhydroxybutyrate (PHB) under conditions of nutrient starvation. The prese...

journal_title：Frontiers in microbiology

authors： Zaldívar Carrillo JA,Stein LY,Sauvageau D

更新日期：2018-07-18 00:00:00

abstract：:The Clostridium genus is a large, diverse group consisting of Gram-positive, spore-forming, obligate anaerobic firmicutes. Among this group are historically notorious pathogens as well as several industrially relevant species with the ability to produce chemical commodities, particularly biofuels, from renewable bioma...

journal_title：Frontiers in microbiology

authors： Joseph RC,Kim NM,Sandoval NR

更新日期：2018-02-12 00:00:00

abstract：:The worldwide dissemination of carbapenemase-producing Enterobacteriaceae (CPE) has become a major therapeutic concern in clinical settings. Enterobacter cloacae is a major pathogen that causes serious hospital-acquired infections. We investigated the clinical characteristics and molecular mechanisms of the first IMP-...

journal_title：Frontiers in microbiology

authors： Lee JH,Bae IK,Lee CH,Jeong S

更新日期：2017-11-28 00:00:00

abstract：:Due to the globally observed increase in antibiotic resistance of bacterial pathogens and the simultaneous decline in new antibiotic developments, the need for alternative inactivation approaches is growing. This is especially true for the treatment of infections with the problematic ESKAPE pathogens, which include En...

journal_title：Frontiers in microbiology

authors： Hoenes K,Bauer R,Meurle T,Spellerberg B,Hessling M

更新日期：2021-01-13 00:00:00

abstract：:Canopy-forming seaweed species of the genus Cystoseira form diverse and productive habitats along temperate rocky coasts of the Mediterranean Sea. Despite numerous studies on the rich macrofauna and flora associated with Cystoseira spp., there is little knowledge about the epiphytic bacteria. We analyzed bacterial pop...

journal_title：Frontiers in microbiology

authors： Mancuso FP,D'Hondt S,Willems A,Airoldi L,De Clerck O

更新日期：2016-04-08 00:00:00

abstract：:Plant rhizospheres encompass a dynamic zone of interactions between microorganisms and their respective plant hosts. For decades, researchers have worked to understand how these complex interactions influence different aspects of plant growth, development, and evolution. Studies of plant-microbial interactions in the ...

journal_title：Frontiers in microbiology

authors： Garcia J,Kao-Kniffin J

更新日期：2018-07-11 00:00:00

abstract：:With the increasing amount of evidence linking certain disorders of the human body to a disturbed gut microbiota, there is a growing interest for compounds that positively influence its composition and activity through diet. Besides the consumption of probiotics to stimulate favorable bacterial communities in the huma...

journal_title：Frontiers in microbiology

authors： Rivière A,Selak M,Lantin D,Leroy F,De Vuyst L

更新日期：2016-06-28 00:00:00

abstract：:The human T-lymphotropic virus (HTLV) is part of the group of retroviruses that share similar routes of transmission to the human immunodeficiency virus (HIV). Coinfection of these viruses can affect the clinical course of both infections, and reports have shown a quicker progression to AIDS and the development of HIV...

journal_title：Frontiers in microbiology

authors： Alencar SP,Souza MC,Fonseca RRS,Menezes CR,Azevedo VN,Ribeiro ALR,Lima SS,Laurentino RV,Barbosa MDAAP,Freitas FB,Oliveira-Filho AB,Machado LFA

更新日期：2020-10-22 00:00:00

abstract：:Insect tea is a unique beverage that is native to Southwestern China and traditionally produced by local farmers in an elaborate process. It consists of insect larvae excrements that are commonly obtained from meal moths (Pyralis farinalis Linnaeus 1758) reared on a specific plant-based diet. We have reconstructed the...

journal_title：Frontiers in microbiology

authors： Mao X,Kusstatscher P,Li H,Chen X,Berg G,Yang M,Cernava T

更新日期：2020-01-29 00:00:00

abstract：:The virulence factor PgtE is an outer membrane protease (omptin) of the zoonotic pathogen Salmonella enterica that causes diseases ranging from gastroenteritis to severe enteric fever. It is surface exposed in bacteria that have a short-chain, i.e., rough LPS, as observed e.g., in bacteria residing inside macrophages ...

journal_title：Frontiers in microbiology

authors： Riva R,Korhonen TK,Meri S

更新日期：2015-02-06 00:00:00

abstract：:Microbiota research often assumes that differences in abundance and identity of microorganisms have unique influences on host physiology. To test this concept mechanistically, germ-free mice are colonized with microbial communities to assess causation. Due to the cost, infrastructure challenges, and time-consuming nat...

journal_title：Frontiers in microbiology

authors： Trinder M,Daisley BA,Dube JS,Reid G

更新日期：2017-04-28 00:00:00

abstract：:Ripening cultures containing fungi and bacteria are widely used in smear-ripened cheese production processes, but little is known about the biotic interactions of typical ripening microorganisms at the surface of cheese. We developed a lab-scale mini-cheese model to investigate the biotic interactions of a synthetic c...

journal_title：Frontiers in microbiology

authors： Pham NP,Landaud S,Lieben P,Bonnarme P,Monnet C

更新日期：2019-08-16 00:00:00

abstract：:Lentinula edodes mycelia (LEM) solid culture extracts contain many bioactive compounds with diverse pharmacological activities such as antitumor, antiviral, and immunopotentiating effects. In this study, we examined the anti-influenza virus activity of LEM in vitro and in vivo. LEM directly inhibited influenza virus g...

journal_title：Frontiers in microbiology

authors： Kuroki T,Lee S,Hirohama M,Taku T,Kumakura M,Haruyama T,Nagata K,Kawaguchi A

更新日期：2018-05-29 00:00:00