Abstract:
:Since early 2018, avian leukosis virus (ALV) has re-emerged throughout six provinces in Northeast and East of China and caused huge economic losses. In different farms, there are significant differences in clinical symptoms, including morbidity, mortality and location of tumours, on affected animals, which implies that the present strains may have different origins and molecular characteristics. In this study, a systematic epidemiological investigation was conducted in 21 farms in six provinces. Results showed that the virus strains present in this outbreak are highly consistent but carry different mutations. All the strains shared 97.0%-99.0% identity with each other and were highly similar to the GD14J2 strain isolated previously, while different insertion fragments can be found in the env gene of different strains, suggesting that the strains of ALV in this outbreak may have the same ancestors but have gone through different evolutionary trajectories. This study demonstrated that these viruses may point to multiple sources of infection, and all should be identified and taken seriously in the formulation of control plans.
journal_name
Transbound Emerg Disjournal_title
Transboundary and emerging diseasesauthors
Zhang Y,Su Q,Zhang Z,Cui Z,Chang S,Zhao Pdoi
10.1111/tbed.13440subject
Has Abstractpub_date
2020-05-01 00:00:00pages
1141-1151issue
3eissn
1865-1674issn
1865-1682journal_volume
67pub_type
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