Treatment of neonatal necrotizing tracheobronchitis with extracorporeal membrane oxygenation and bronchoscopy.

Abstract:

:Necrotizing tracheobronchitis has recently been described as a complication of mechanical ventilation of newborns with respiratory failure. Despite the use of bronchoscopy, 45% of the reported patients to date have died. In this study, we report the use of extracorporeal membrane oxygenation (ECMO) to stabilize two patients with necrotizing tracheobronchitis. While supported by bypass, both patients underwent prolonged bronchoscopies with removal of extensive amounts of tracheal debris. ECMO provided efficient oxygenation in the face of near total airway occlusion, and permitted far more extensive bronchoscopic debridement and lavage than would have been possible if the lungs were required for oxygenation. In addition, ECMO provided a period of lung "rest" during which ventilator settings were reduced, thus minimizing further barotrauma and allowing for lung and airway healing. Both patients recovered without significant respiratory sequelae. ECMO and bronchoscopy are effective forms of therapy for patients with life-threatening necrotizing tracheobronchitis when conventional modalities of treatment have failed.

journal_name

J Pediatr Surg

authors

Michael EJ,Zwillenberg D,Furnari A,Sheppard L,Desai HJ,Wolfson PJ,Robinson NB,Kornhauser M,Mobley S,Branca PA

doi

10.1016/s0022-3468(88)80225-2

subject

Has Abstract

pub_date

1988-09-01 00:00:00

pages

798-801

issue

9

eissn

0022-3468

issn

1531-5037

pii

S002234688800257X

journal_volume

23

pub_type

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