New attachment achieved by guided tissue regeneration in beagle dogs.

Abstract:

:This study tested the effects of using a Gore-Tex periodontal material on new connective tissue attachment in beagle dogs with natural periodontitis. Seven female beagle dogs with advanced periodontitis were selected and given thorough root debridement. Under general anesthesia four weeks later, mucoperiosteal flaps were raised involving all mandibular premolars and first molars. Gore-Tex periodontal material was adapted to all premolars, and the flaps were sutured tightly, keeping the material covered. The first molars acted as controls, receiving only surgery. Some material was removed in one month, while other materials were removed eight to 10 weeks after surgery. All dogs were sacrificed at three months. After processing, descriptive histology and histometrics were carried out, evaluating new connective tissue attachment, bone response and epithelial downgrowth. Results were statistically analyzed, using paired t tests. They showed new connective tissue attachment with cementum deposition in areas where the material was used. Also, the epithelial downgrowth was reduced in these areas. In the controls, minimal connective tissue attachment was found, with the area healing by a long junctional epithelium. Statistical analysis showed significant differences (P less than 0.05) favoring experimental areas both in the increase of new connective tissue attachment and in the decrease of epithelial downgrowth. No differences were found between areas where the material was removed in one month or left longer in place. No difference in bone response was found. Gore-Tex material was effective in blocking gingival epithelial downgrowth and connective tissue proliferation, promoting new attachment according to the principle of "guided tissue regeneration."

journal_name

J Periodontol

authors

Caffesse RG,Smith BA,Castelli WA,Nasjleti CE

doi

10.1902/jop.1988.59.9.589

subject

Has Abstract

pub_date

1988-09-01 00:00:00

pages

589-94

issue

9

eissn

0022-3492

issn

1943-3670

journal_volume

59

pub_type

杂志文章
  • Cementai Tear Related to Rapid Periodontal Breakdown: A Case Report.

    abstract::Cemental tears have been described both in exposed and unexposed cementum. The phenomenon is believed to be elicited by overloading or acute trauma from occlusion. In this case report a patient, with a history of periodontal health, presented with an acute periodontal lesion on the distal aspect of a bridge abutment t...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1992.63.3.220

    authors: Haney JM,Leknes KN,Lie T,Selvig KA,Wikesjö UME

    更新日期:1992-03-01 00:00:00

  • Plasma and saliva concentrations of phenytoin and 5-(4-hydroxyphenyl)-5-phenylhydantoin in relation to the incidence and severity of phenytoin-induced gingival overgrowth in epileptic patients.

    abstract::This study examined the relationships between plasma and saliva concentrations of phenytoin and 5-(4-hydroxyphenyl)-5-phenylhydantoin (HPPH), the major metabolite of phenytoin in man, and the prevalence and severity of gingival overgrowth. Thirty-six adult epileptic patients who had been receiving phenytoin for greate...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1996.67.6.597

    authors: Ball DE,McLaughlin WS,Seymour RA,Kamali F

    更新日期:1996-06-01 00:00:00

  • Changes of subgingival total colony forming units and black pigmented bacteroides after a single irrigation of periodontal pockets with 1.64% SnF2.

    abstract::Periodontal pockets of 11 subjects were irrigated once with either 1.64% SnF2 or saline applied by syringe. Changes on the total anaerobic colony forming units (CFU) and black pigmented bacteroides (BPBs) of the irrigated pockets were assessed for 31 days. The results showed little change of the CFUs by either single ...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1985.56.6.330

    authors: Schmid E,Kornman KS,Tinanoff N

    更新日期:1985-06-01 00:00:00

  • Effect of implant cleaning on titanium particle dissolution and cytocompatibility.

    abstract:BACKGROUND:Peri-implantitis treatments are mainly based on protocols for teeth but have not shown favorable outcomes for implants. The potential role of titanium dissolution products in peri-implantitis necessitate the consideration of material properties in devising treatment protocols. We assessed implant cleaning in...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1002/JPER.20-0186

    authors: Kotsakis GA,Black R,Kum J,Berbel L,Sadr A,Karoussis I,Simopoulou M,Daubert D

    更新日期:2020-08-26 00:00:00

  • Removal of an amalgam tattoo using a subepithelial connective tissue graft and laser deepithelialization.

    abstract:BACKGROUND:A 56-year-old female presented for periodontal treatment with a large amalgam tattoo located in alveolar mucosa on the facial aspect of her maxillary central incisors. The lesion had been present for 42 years since having endodontic surgery at teeth #8 and #9 after a traumatic childhood incident. METHODS:A ...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2009.080613

    authors: Campbell CM,Deas DE

    更新日期:2009-05-01 00:00:00

  • Clinical recommendations for avoiding and managing surgical complications associated with implant dentistry: a review.

    abstract::Proposing to place endosseous implants is an integral facet of dental treatment plans. Their insertion is usually associated with a low incidence of untoward events. However, despite careful planning, surgical complications can arise: infection, intraoral hemorrhage, wound dehiscence, postoperative pain, lack of prima...

    journal_title:Journal of periodontology

    pub_type: 杂志文章,评审

    doi:10.1902/jop.2008.070067

    authors: Greenstein G,Cavallaro J,Romanos G,Tarnow D

    更新日期:2008-08-01 00:00:00

  • One-stage full-mouth versus partial-mouth scaling and root planing during the effective half-life of systemically administered azithromycin.

    abstract:BACKGROUND:One-stage full-mouth scaling and root planing (FM-SRP) in combination with systemically administered azithromycin was shown to be clinically and bacteriologically effective in the treatment of chronic periodontitis. However, FM-SRP requires 2 hours for completion. Azithromycin has a long half-life. Therefore...

    journal_title:Journal of periodontology

    pub_type: 杂志文章,随机对照试验

    doi:10.1902/jop.2009.090067

    authors: Yashima A,Gomi K,Maeda N,Arai T

    更新日期:2009-09-01 00:00:00

  • Subgingival plaque removal using a new air-polishing device.

    abstract:BACKGROUND:The purpose of this study is to evaluate the safety, patient acceptance, and short-term microbiologic effect of a new air-polishing device in subjects in maintenance care with residual pockets > or =5 mm. METHODS:This was an examiner-masked, randomized, split-mouth clinical trial. A new disposable nozzle, a...

    journal_title:Journal of periodontology

    pub_type: 杂志文章,随机对照试验

    doi:10.1902/jop.2009.090394

    authors: Moëne R,Décaillet F,Andersen E,Mombelli A

    更新日期:2010-01-01 00:00:00

  • Calcium hydroxide and potassium nitrate as desensitizing agents for hypersensitive root surfaces.

    abstract::The purpose of this investigation was to evaluate calcium hydroxide and potassium nitrate individually as densensitizing agents for hypersensitive root surfaces. The apparatus used in the experiment to measure hypersensitivity was (a) a thermo-electric stimulating device to measure hot and cold stimulation quantitativ...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1977.48.10.667

    authors: Green BL,Green ML,McFall WT Jr

    更新日期:1977-10-01 00:00:00

  • Relationship among clinical periodontal, microbiologic parameters and lung function in participants with chronic obstructive pulmonary disease.

    abstract:BACKGROUND:The aim of this study was to evaluate the relationship among clinical periodontal, microbiologic parameters and lung function in participants with chronic obstructive pulmonary disease (COPD). METHODS:A total of 160 participants were recruited, including 80 participants with COPD (COPD group) and 80 partici...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1002/JPER.17-0705

    authors: Tan L,Tang X,Pan C,Wang H,Pan Y

    更新日期:2019-02-01 00:00:00

  • Inter-implant bone height changes in anterior maxillary immediate and non-immediate adjacent dental implants.

    abstract:BACKGROUND:The purpose of this study was to evaluate inter-implant bone crest height changes between immediate and non-immediate dental implants placed in the anterior maxillary region. METHODS:A retrospective study was conducted on consecutively treated patients requiring at least two adjacent implants in the anterio...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2007.060443

    authors: Kupershmidt I,Levin L,Schwartz-Arad D

    更新日期:2007-06-01 00:00:00

  • Association between periodontal pockets and elevated cholesterol and low density lipoprotein cholesterol levels.

    abstract:BACKGROUND:Periodontitis is associated with increased prevalence of cardiovascular morbidity and mortality; however, the nature of this association is unclear. There is a rationale that indicates that the presence of periodontal pockets which can harbor pathogenic microorganisms and evoke a host response could elicit a...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2002.73.5.494

    authors: Katz J,Flugelman MY,Goldberg A,Heft M

    更新日期:2002-05-01 00:00:00

  • Employing a transgenic animal model to obtain cementoblasts in vitro.

    abstract:BACKGROUND:Proper formation of cementum, a mineralized tissue lining the tooth root surface, is required for development of a functional periodontal ligament. Further, the presence of healthy cementum is considered to be an important criterion for predictable restoration of periodontal tissues lost as a consequence of ...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2000.71.1.63

    authors: D'Errico JA,Berry JE,Ouyang H,Strayhorn CL,Windle JJ,Somerman MJ

    更新日期:2000-01-01 00:00:00

  • Distinctive molecular composition of human gingival interdental papilla.

    abstract:BACKGROUND:Gingiva is composed of attached and marginal (free) gingiva and interdental papilla. Increasing esthetic demands in dentistry have created a need to restore all parts of the gingiva. However, the interdental papilla has limited regeneration potential compared to other parts of the gingiva. It also is more su...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2007.060165

    authors: Csiszar A,Wiebe C,Larjava H,Häkkinen L

    更新日期:2007-02-01 00:00:00

  • Porphyromonas gingivalis HmuY-induced production of interleukin-6 and IL-6 polymorphism in chronic periodontitis.

    abstract:BACKGROUND:In chronic periodontitis (CP), the gene polymorphism of interleukin-6 (IL-6) to 174C/G has been associated with the altered production of this cytokine. The aim of this pilot study is to compare the allelic and genotypic frequencies in patients with CP with control individuals without periodontitis (NP) and ...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2012.120230

    authors: Trindade SC,Olczak T,Gomes-Filho IS,de Moura-Costa LF,Vale VC,Galdino-Neto M,Alves Dos Santos H,de Carvalho Filho PC,Stocker A,Bendicho MT,Xavier MT,de Moraes Marcílio Cerqueira E,Meyer R

    更新日期:2013-05-01 00:00:00

  • A long-term evaluation of composite-bonded natural/resin teeth as replacement of lower incisors with terminal periodontitis.

    abstract:BACKGROUND:In patients with severe peridontitis, lower incisors are prone to terminal breakdown. This study assessed the longevity of composite-bonded resin/natural teeth (reinforced only with a stainless steel mesh) as replacements for periodontally lost lower incisors. METHODS:Besides the longevity of the restoratio...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1999.70.2.205

    authors: Quirynen M,Mongardini C,Lambrechts P,De Geyseleer C,Labella R,Vanherle G,van Steenberghe D

    更新日期:1999-02-01 00:00:00

  • Multi-level statistical models in studies of periodontal diseases.

    abstract::Periodontal data typically have a hierarchical structure, with sites grouped within individuals, and individuals grouped within communities. Also, the occasion may be regarded as another level since the acquired knowledge indicates that periodontal disease activity may vary over time. Conventional statistical tests ar...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1992.63.8.690

    authors: Albandar JM,Goldstein H

    更新日期:1992-08-01 00:00:00

  • A histochemical investigation of the bone formation process by guided bone regeneration in rat jaws. Effect of PTFE membrane application periods on newly formed bone.

    abstract:BACKGROUND:Guided bone regeneration (GBR) has been widely utilized for the promotion of bone augmentation in bone loss areas. However, little information has been available regarding chronological changes in newly formed bone and alterations in the nature of newly formed bone after removal of a barrier membrane. The pr...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2000.71.3.341

    authors: Ohnishi H,Fujii N,Futami T,Taguchi N,Kusakari H,Maeda T

    更新日期:2000-03-01 00:00:00

  • Clinical, laboratory, and immunological studies of a family with a high prevalence of generalized prepubertal and juvenile periodontitis.

    abstract::A study of a consanguineous family with a high prevalence of localized juvenile periodontitis (LJP) and generalized prepubertal periodontitis (GPP) was done over a 7-and-a-half year period. The parents had adult periodontitis, while 2 daughters, aged 13 and 15, had LJP. Furthermore, 2 other daughters, ages 14 and 10, ...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1992.63.5.457

    authors: López NJ

    更新日期:1992-05-01 00:00:00

  • Absence of histologic signs of chronic inflammation following closed subgingival scaling and root planing using the dental endoscope: human biopsies - a pilot study.

    abstract:BACKGROUND:The primary goal of periodontal therapy is the reduction or elimination of inflammation. Traditionally, this is accomplished through removal of subgingival tooth-borne accretions using non-surgical and/or surgical treatment modalities. Numerous studies indicated the difficulty in removing these accretions to...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2008.080190

    authors: Wilson TG Jr,Carnio J,Schenk R,Myers G

    更新日期:2008-11-01 00:00:00

  • Healing responses to grafting of combined collagen-decalcified bone in periodontal defects in dogs.

    abstract::The feasibility of a new combined collagen gel-autolysed antigen-extracted allogeneic bone implant was tested. Its effect on gaining new attachment in surgically created defects in four dogs was evaluated over 24 weeks. As controls, sites receiving implants of the bone implant alone, nonimplanted and untreated defects...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1986.57.2.84

    authors: Blumenthal N,Sabe T,Barrington E

    更新日期:1986-02-01 00:00:00

  • Repair of Class II furcation defects after a reparative tissue graft obtained from extraction sockets treated with growth factors: a histologic and histometric study in dogs.

    abstract:BACKGROUND:Reparative tissue of extraction sockets was proposed as grafting material in the treatment of periodontal defects. Our hypothesis was that the addition of growth factors to extraction sockets improves the regenerative potential of this tissue when used as a graft. The objective of the present study was to an...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2005.76.10.1681

    authors: Soares FP,Hayashi F,Yorioka CW,Pannuti CM,Gioso MA,de Lima LA,Romito GA,Pustiglioni FE

    更新日期:2005-10-01 00:00:00

  • The effect of periodontal treatment on serum leptin, interleukin-6, and C-reactive protein.

    abstract:BACKGROUND:Previous studies suggest that periodontitis is closely related to obesity and metabolic syndrome. Leptin, a pleiotrophic hormone produced by adipose tissue, has been reported to be related to periodontitis. This study investigates the effects of periodontal treatment on the serum levels of leptin and other c...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2010.090741

    authors: Shimada Y,Komatsu Y,Ikezawa-Suzuki I,Tai H,Sugita N,Yoshie H

    更新日期:2010-08-01 00:00:00

  • Zirconium dioxide implant abutments for posterior single-tooth replacement: first results.

    abstract:BACKGROUND:Prefabricated implant abutments made of zirconium dioxide (yttria-stabilized polycrystalline tetragonal zirconia; Y-TZP) have proved to be useful in the esthetically demanding anterior region and may also be useful for premolar and molar replacement because of their obvious positive impact on the health of p...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2009.090274

    authors: Nothdurft FP,Pospiech PR

    更新日期:2009-12-01 00:00:00

  • Metformin ameliorates experimental diabetic periodontitis independently of mammalian target of rapamycin (mTOR) inhibition by reducing NIMA-related kinase 7(Nek7) expression.

    abstract:BACKGROUND:Metformin, a classical treatment for diabetes mellitus, has shown sound anti-inflammatory effects. Emerging studies have focused on the mechanism underlying inflammation-related diabetic complications, such as diabetic periodontitis. Herein, we investigated the anti-inflammatory effects of metformin on the N...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1002/jper.10311

    authors: Zhou X,Zhang P,Wang Q,Ji N,Xia S,Ding Y,Wang Q

    更新日期:2019-02-19 00:00:00

  • The association between smoking cessation and periodontal status and salivary proteinase levels.

    abstract:BACKGROUND:Little information is available about the effects of the cessation of cigarette smoking on oral health, although cigarette smoking has been shown to be associated with a variety of oral diseases. The aim of this study was to compare periodontal status, salivary proteolytic activity, especially collagenase-2 ...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1999.70.11.1361

    authors: Liede KE,Haukka JK,Hietanen JH,Mattila MH,Rönkä H,Sorsa T

    更新日期:1999-11-01 00:00:00

  • Periodontal treatment decreases levels of antibodies to Porphyromonas gingivalis and citrulline in patients with rheumatoid arthritis and periodontitis.

    abstract:BACKGROUND:Porphyromonas gingivalis has been implicated as an etiologic agent of rheumatoid arthritis (RA) because of the expression of peptidylarginine deiminase. The present study evaluates whether periodontal treatment may affect serum antibodies to P. gingivalis and citrulline levels in relation to disease activity...

    journal_title:Journal of periodontology

    pub_type: 杂志文章,随机对照试验

    doi:10.1902/jop.2013.130079

    authors: Okada M,Kobayashi T,Ito S,Yokoyama T,Abe A,Murasawa A,Yoshie H

    更新日期:2013-12-01 00:00:00

  • A Novel Rat Model of Polymicrobial Peri-Implantitis: A Preliminary Study.

    abstract:BACKGROUND:Peri-implantitis is a complex polymicrobial biofilm-induced inflammatory osteolytic gingival infection that results in orofacial implant failures. To the best knowledge of the authors, there are no preclinical in vivo studies in implant dentistry that have investigated the inflammatory response to known micr...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2016.160273

    authors: Koutouzis T,Eastman C,Chukkapalli S,Larjava H,Kesavalu L

    更新日期:2017-02-01 00:00:00

  • Efficacy of preprocedural mouth rinsing in reducing aerosol contamination produced by ultrasonic scaler: a pilot study.

    abstract:BACKGROUND:The aerosol generated by an ultrasonic scaler contains microorganisms that can penetrate into the body through the respiratory system of dental surgeons and patients. The aim of this pilot study is to evaluate and compare the efficacy of commercially available preprocedural mouthrinses containing 0.2% chlorh...

    journal_title:Journal of periodontology

    pub_type: 杂志文章,随机对照试验

    doi:10.1902/jop.2013.120616

    authors: Gupta G,Mitra D,Ashok KP,Gupta A,Soni S,Ahmed S,Arya A

    更新日期:2014-04-01 00:00:00

  • Gingival involvement of oral lichen planus.

    abstract:BACKGROUND:Oral lichen planus (OLP) is one of the most common oral mucosa disorders. OLP gingival involvement is very frequently observed and is characterized by a wide range of clinical appearance, symptomatology, and locations. The purpose of this study was to analyze the prevalence and clinical aspects of gingival l...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2007.060303

    authors: Camacho-Alonso F,López-Jornet P,Bermejo-Fenoll A

    更新日期:2007-04-01 00:00:00