Epidemiology of COVID-19 Among Children in China.

Abstract:

OBJECTIVE:To identify the epidemiological characteristics and transmission patterns of pediatric patients with the 2019 novel coronavirus disease (COVID-19) in China. METHODS:Nationwide case series of 2135 pediatric patients with COVID-19 reported to the Chinese Center for Disease Control and Prevention from January 16, 2020, to February 8, 2020, were included. The epidemic curves were constructed by key dates of disease onset and case diagnosis. Onset-to-diagnosis curves were constructed by fitting a log-normal distribution to data on both onset and diagnosis dates. RESULTS:There were 728 (34.1%) laboratory-confirmed cases and 1407 (65.9%) suspected cases. The median age of all patients was 7 years (interquartile range: 2-13 years), and 1208 case patients (56.6%) were boys. More than 90% of all patients had asymptomatic, mild, or moderate cases. The median time from illness onset to diagnoses was 2 days (range: 0-42 days). There was a rapid increase of disease at the early stage of the epidemic, and then there was a gradual and steady decrease. The disease rapidly spread from Hubei province to surrounding provinces over time. More children were infected in Hubei province than any other province. CONCLUSIONS:Children of all ages appeared susceptible to COVID-19, and there was no significant sex difference. Although clinical manifestations of children's COVID-19 cases were generally less severe than those of adult patients, young children, particularly infants, were vulnerable to infection. The distribution of children's COVID-19 cases varied with time and space, and most of the cases were concentrated in Hubei province and surrounding areas. Furthermore, this study provides strong evidence of human-to-human transmission.

journal_name

Pediatrics

journal_title

Pediatrics

authors

Dong Y,Mo X,Hu Y,Qi X,Jiang F,Jiang Z,Tong S

doi

10.1542/peds.2020-0702

subject

Has Abstract

pub_date

2020-06-01 00:00:00

issue

6

eissn

0031-4005

issn

1098-4275

pii

peds.2020-0702

journal_volume

145

pub_type

杂志文章
  • Heat stress from enclosed vehicles: moderate ambient temperatures cause significant temperature rise in enclosed vehicles.

    abstract:OBJECTIVE:Each year, children die from heat stroke after being left unattended in motor vehicles. In 2003, the total was 42, up from a national average of 29 for the past 5 years. Previous studies found that on days when ambient temperatures exceeded 86 degrees F, the internal temperatures of the vehicle quickly reache...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2004-2368

    authors: McLaren C,Null J,Quinn J

    更新日期:2005-07-01 00:00:00

  • Low rates of influenza immunization in young children under Ontario's universal influenza immunization program.

    abstract:OBJECTIVES:To determine physician-administered influenza vaccine coverage for children aged 6 to 23 months in a jurisdiction with a universal influenza immunization program during 2002-2009 and to describe predictors of vaccination. METHODS:By using hospital records, we identified all infants born alive in Ontario hos...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2011-2441

    authors: Campitelli MA,Inoue M,Calzavara AJ,Kwong JC,Guttmann A

    更新日期:2012-06-01 00:00:00

  • Genome-wide expression profiles in very low birth weight infants with neonatal sepsis.

    abstract:BACKGROUND:Bacterial sepsis is associated with high morbidity and mortality in preterm infants. However, diagnosis of sepsis and identification of the causative agent remains challenging. Our aim was to determine genome-wide expression profiles of very low birth weight (VLBW) infants with and without bacterial sepsis a...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2013-2552

    authors: Cernada M,Serna E,Bauerl C,Collado MC,Pérez-Martínez G,Vento M

    更新日期:2014-05-01 00:00:00

  • Cardiovascular risk factors from birth to 7 years of age: the Bogalusa Heart Study. Dietary intakes.

    abstract::Dietary patterns and racial differences in nutrient intake were observed in children 6 months to 4 years of age in the Bogalusa Heart Study. Even in this sample of young children, the composition of the intakes of the majority of children was not compatible with prudent recommendations of less than 35% and 10% of ener...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Nicklas TA,Farris RP,Major C,Frank GC,Webber LS,Cresanta JL,Berenson GS

    更新日期:1987-11-01 00:00:00

  • Stakeholder Perspectives on Research and Practice in Autism and Transition.

    abstract:OBJECTIVES:Individuals with autism spectrum disorder (ASD) are reported to experience significant challenges during the transition to adulthood. Although recent evidence indicates that individuals with ASD experience poor outcomes in adulthood, little is understood about the contributing factors. In this qualitative st...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2016-4300F

    authors: Kuo AA,Crapnell T,Lau L,Anderson KA,Shattuck P

    更新日期:2018-04-01 00:00:00

  • Asthma as a barrier to children's physical activity: implications for body mass index and mental health.

    abstract:OBJECTIVES:The purpose of this work was to identify barriers to physical activity in children with asthma and to compare their customary activity levels, BMI and emotional well-being with that of children with other medical conditions. It was hypothesized that children with asthma would have higher BMI and lower levels...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2006-1846

    authors: Glazebrook C,McPherson AC,Macdonald IA,Swift JA,Ramsay C,Newbould R,Smyth A

    更新日期:2006-12-01 00:00:00

  • Continuity of pediatric ambulatory care in a universally insured population.

    abstract:OBJECTIVE:To describe the prevalence of continuity of care over a 5-year period in a complete cohort of urban children universally insured for medical care provided under fee-for-service reimbursement. METHOD:All children enrolled in the study were born to women living in metropolitan Winnipeg between July 1, 1987 and...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Mustard CA,Mayer T,Black C,Postl B

    更新日期:1996-12-01 00:00:00

  • Congenital malaria: a rare cause of splenomegaly and anemia in an American infant.

    abstract::A 38-day-old infant had fever, jaundice, hepatosplenomegaly, and a hemolytic anemia. A peripheral blood smear demonstrated intraerythrocytic malarial parasites identified as Plasmodium vivax. Maternal and infant sera contained antibodies to this species. A directed history revealed the mother had suffered several febr...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Thompson D,Pegelow C,Underman A,Powars D

    更新日期:1977-08-01 00:00:00

  • Sleepwalking and sleep terrors in prepubertal children: what triggers them?

    abstract:OBJECTIVES:To evaluate the clinical presentation and polysomnography of prepubertal children with repetitive sleep terrors and sleepwalking, to compare them with a control group, and to evaluate the treatment of associated sleep disorders. METHODS:Patients with complaint of sleep terrors with or without sleepwalking w...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.111.1.e17

    authors: Guilleminault C,Palombini L,Pelayo R,Chervin RD

    更新日期:2003-01-01 00:00:00

  • Population-based studies of varicella complications.

    abstract::Population-based data on varicella complications are presented using information both from national sample surveys of hospitalizations and physician office visits and from reviews of medical records for all cases occurring within one community (Olmsted County, Minnesota) during a specified period. Acute cerebellar ata...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Guess HA,Broughton DD,Melton LJ 3rd,Kurland LT

    更新日期:1986-10-01 00:00:00

  • The discovery of phenylketonuria: the story of a young couple, two retarded children, and a scientist.

    abstract::In the 1920s, a little girl 3 years of age was brought from China to the United States by her American mother. Although the child was beautiful, her mind was not developing. The grief-stricken mother had consulted doctors in China, but they could neither diagnose the problem nor provide treatment. Morning and night th...

    journal_title:Pediatrics

    pub_type: 传,历史文章,杂志文章

    doi:10.1542/peds.105.1.89

    authors: Centerwall SA,Centerwall WR

    更新日期:2000-01-01 00:00:00

  • The Improving Renal Outcomes Collaborative: Blood Pressure Measurement in Transplant Recipients.

    abstract:BACKGROUND AND OBJECTIVES:Hypertension is highly prevalent in pediatric kidney transplant recipients and contributes to cardiovascular death and graft loss. Improper blood pressure (BP) measurement limits the ability to control hypertension in this population. Here, we report multicenter efforts from the Improving Rena...

    journal_title:Pediatrics

    pub_type: 杂志文章,多中心研究

    doi:10.1542/peds.2019-2833

    authors: Seifert ME,Dahale DS,Kamel M,Winterberg PD,Barletta GM,Belsha CW,Chaudhuri A,Flynn JT,Garro R,George RP,Goebel JW,Kershaw DB,Matossian D,Misurac J,Nailescu C,Nguyen CR,Pearl M,Pollack A,Pruette CS,Singer P,VanSick

    更新日期:2020-07-01 00:00:00

  • Fatal malignant hyperthermia-like syndrome with rhabdomyolysis complicating the presentation of diabetes mellitus in adolescent males.

    abstract:OBJECTIVE:This report describes a new fatal syndrome observed in adolescent males at the initial presentation of diabetes mellitus. The features include hyperglycemic hyperosmolar coma complicated by a malignant hyperthermia-like picture with fever, rhabdomyolysis, and severe cardiovascular instability. DESIGN:Case se...

    journal_title:Pediatrics

    pub_type: 杂志文章,多中心研究,评审

    doi:10.1542/peds.111.6.1447

    authors: Hollander AS,Olney RC,Blackett PR,Marshall BA

    更新日期:2003-06-01 00:00:00

  • Prevalence of Autism Spectrum Disorder in Preterm Infants: A Meta-analysis.

    abstract:CONTEXT:Evidence is emerging that preterm infants are at risk for autism spectrum disorder (ASD). OBJECTIVES:To conduct a systematic review and meta-analysis to estimate the prevalence of ASD in preterm infants. DATA SOURCES:Medline (via PubMed and Ovid), Embase, PsycINFO, and relevant conference proceedings were sea...

    journal_title:Pediatrics

    pub_type: 杂志文章,meta分析

    doi:10.1542/peds.2018-0134

    authors: Agrawal S,Rao SC,Bulsara MK,Patole SK

    更新日期:2018-09-01 00:00:00

  • "Greenlight study": a controlled trial of low-literacy, early childhood obesity prevention.

    abstract::Children who become overweight by age 2 years have significantly greater risks of long-term health problems, and children in low-income communities, where rates of low adult literacy are highest, are at increased risk of developing obesity. The objective of the Greenlight Intervention Study is to assess the effectiven...

    journal_title:Pediatrics

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1542/peds.2013-3867

    authors: Sanders LM,Perrin EM,Yin HS,Bronaugh A,Rothman RL,Greenlight Study Team.

    更新日期:2014-06-01 00:00:00

  • American Academy of Pediatrics: Risk of injury from baseball and softball in children.

    abstract::This statement updates the 1994 American Academy of Pediatrics policy statement on baseball and softball injuries in children. Current studies on acute, overuse, and catastrophic injuries are reviewed with emphasis on the causes and mechanisms of injury. This information serves as a basis for recommending safe trainin...

    journal_title:Pediatrics

    pub_type: 指南,杂志文章

    doi:10.1542/peds.107.4.782

    authors: Committee on Sports Medicine and Fitness.

    更新日期:2001-04-01 00:00:00

  • Prediction of death for extremely low birth weight neonates.

    abstract:OBJECTIVE:To compare multiple logistic regression and neural network models in predicting death for extremely low birth weight neonates at 5 time points with cumulative data sets, as follows: scenario A, limited prenatal data; scenario B, scenario A plus additional prenatal data; scenario C, scenario B plus data from t...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2004-2099

    authors: Ambalavanan N,Carlo WA,Bobashev G,Mathias E,Liu B,Poole K,Fanaroff AA,Stoll BJ,Ehrenkranz R,Wright LL,National Institute of Child Health and Human Development Neonatal Research Network.

    更新日期:2005-12-01 00:00:00

  • Serum immunoreactive pancreatic lipase and cationic trypsinogen for the assessment of exocrine pancreatic function in older patients with cystic fibrosis.

    abstract::Indirect and qualitative tests of pancreatic function are commonly used to screen patients with cystic fibrosis for pancreatic insufficiency. In an attempt to develop a more quantitative assessment, we compared the usefulness of measuring serum pancreatic lipase using a newly developed enzyme-linked immunosorbent immu...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Cleghorn G,Benjamin L,Corey M,Forstner G,Dati F,Durie P

    更新日期:1986-03-01 00:00:00

  • Management of congenital adrenal hyperplasia using serum dehydroepiandrosterone sulfate and 17-hydroxyprogesterone concentrations.

    abstract::Simultaneous serum concentrations of dehydroepiandrosterone sulfate (DHEA-S) and 17-hydroxyprogesterone (17-OHP) were compared with urinary 17-ketosteroid (17-KS) and pregnanetriol (PT) excretion during therapy in 18 prepubertal patients with the 21-hydroxylase deficiency form of congenital adrenal hyperplasia (CAH). ...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Golden MP,Lippe BM,Kaplan SA,Lavin N,Slavin J

    更新日期:1978-06-01 00:00:00

  • Principles of Care for Young Adults With Co-Occurring Psychiatric and Substance Use Disorders.

    abstract::Over 50% of young adults (defined as individuals aged 18-25 years) with substance use disorders (SUDs) have at least 1 co-occurring psychiatric disorder, and the presence of co-occurring disorders worsens SUD outcomes. Treatment of both co-occurring psychiatric disorders and SUDs in young adults is imperative for opti...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2020-023523F

    authors: Spencer AE,Valentine SE,Sikov J,Yule AM,Hsu H,Hallett E,Xuan Z,Silverstein M,Fortuna L

    更新日期:2021-01-01 00:00:00

  • When is lack of supervision neglect?

    abstract::Occasionally, pediatricians become aware of children who are inadequately supervised. More frequently, pediatricians treat children for traumatic injuries or ingestions that they suspect could have been prevented with better supervision. This clinical report contains guidance for pediatricians considering a referral t...

    journal_title:Pediatrics

    pub_type: 指南,杂志文章

    doi:10.1542/peds.2006-1780

    authors: Hymel KP,Committee on Child Abuse and Neglect.

    更新日期:2006-09-01 00:00:00

  • Educational principles of community-based education.

    abstract::Much of medical education remains teacher centered, as exemplified by the continued emphasis on lectures. Increasingly, however, the importance of the learner is being recognized and acknowledged in medical school curricula. The distinction between teaching and learning is also an issue for graduate medical education;...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Roberts KB

    更新日期:1996-12-01 00:00:00

  • A Case of a 15-Month-Old With Periorbital Edema and Severe Anemia.

    abstract::This is the case of a previously healthy 15-month-old girl who initially presented to her primary pediatrician with a 2-week history of intermittent periorbital edema. The edema had improved by the time of the visit, and a urine specimen was unable to be obtained in the clinic. A routine fingerstick demonstrated anemi...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2019-0391

    authors: Kamzan AD,Newcomer CA,Wozniak LJ,Federman NC,Kim LS

    更新日期:2020-03-01 00:00:00

  • Neurodevelopment and in utero antiretroviral exposure of HIV-exposed uninfected infants.

    abstract:OBJECTIVE:Antiretroviral (ARV) drugs are routinely provided to HIV-infected pregnant women to prevent HIV mother-to-child transmission. Although ARV use has significantly reduced mother-to-child transmission to <2% in the United States, it remains crucial to monitor uninfected infants and children for adverse consequen...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2009-1112

    authors: Williams PL,Marino M,Malee K,Brogly S,Hughes MD,Mofenson LM,PACTG 219C Team.

    更新日期:2010-02-01 00:00:00

  • Children, adolescents, obesity, and the media.

    abstract::Obesity has become a worldwide public health problem. Considerable research has shown that the media contribute to the development of child and adolescent obesity, although the exact mechanism remains unclear. Screen time may displace more active pursuits, advertising of junk food and fast food increases children's re...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2011-1066

    authors: Council on Communications and Media.,Strasburger VC

    更新日期:2011-07-01 00:00:00

  • Dietary recommendations for children and adolescents: a guide for practitioners.

    abstract::Since the American Heart Association last presented nutrition guidelines for children, significant changes have occurred in the prevalence of cardiovascular risk factors and nutrition behaviors in children. Overweight has increased, whereas saturated fat and cholesterol intake have decreased, at least as percentage of...

    journal_title:Pediatrics

    pub_type: 杂志文章,实务指引

    doi:10.1542/peds.2005-2374

    authors: Gidding SS,Dennison BA,Birch LL,Daniels SR,Gillman MW,Lichtenstein AH,Rattay KT,Steinberger J,Stettler N,Van Horn L,American Heart Association.

    更新日期:2006-02-01 00:00:00

  • Delaying second births among adolescent mothers: a randomized, controlled trial of a home-based mentoring program.

    abstract:CONTEXT:Rates of rapid second births among low-income black adolescent mothers range from 20% to 50%. Most efforts to prevent rapid second births have been unsuccessful. OBJECTIVES:There were 4 objectives: (1) to examine whether a home-based mentoring intervention was effective in preventing second births within 2 yea...

    journal_title:Pediatrics

    pub_type: 杂志文章,随机对照试验

    doi:10.1542/peds.2005-2318

    authors: Black MM,Bentley ME,Papas MA,Oberlander S,Teti LO,McNary S,Le K,O'Connell M

    更新日期:2006-10-01 00:00:00

  • Cultural bias in the AAP's 2012 Technical Report and Policy Statement on male circumcision.

    abstract::The American Academy of Pediatrics recently released its new Technical Report and Policy Statement on male circumcision, concluding that current evidence indicates that the health benefits of newborn male circumcision outweigh the risks. The technical report is based on the scrutiny of a large number of complex scient...

    journal_title:Pediatrics

    pub_type: 评论,杂志文章

    doi:10.1542/peds.2012-2896

    authors: Frisch M,Aigrain Y,Barauskas V,Bjarnason R,Boddy SA,Czauderna P,de Gier RP,de Jong TP,Fasching G,Fetter W,Gahr M,Graugaard C,Greisen G,Gunnarsdottir A,Hartmann W,Havranek P,Hitchcock R,Huddart S,Janson S,Jaszczak P

    更新日期:2013-04-01 00:00:00

  • Parental Smoking Cessation: Impacting Children's Tobacco Smoke Exposure in the Home.

    abstract:OBJECTIVES:There is no safe or risk-free level of tobacco use or tobacco smoke exposure. In this randomized controlled trial, we tested a tobacco control intervention in families and specifically evaluated a tailored cessation intervention for the parents and/or caregivers (Ps/Cs) who were smokers while their children ...

    journal_title:Pediatrics

    pub_type: 杂志文章,随机对照试验

    doi:10.1542/peds.2017-1026M

    authors: Caldwell AL,Tingen MS,Nguyen JT,Andrews JO,Heath J,Waller JL,Treiber FA

    更新日期:2018-01-01 00:00:00

  • Iatrogenic arteriovenous fistula after multiple arterial punctures.

    abstract::Multiple arterial punctures in the neonate can result in iatrogenic arteriovenous fistula formation. In one case, a 3-month-old infant who had been born prematurely was noted to have physical findings consistent with arteriovenous malformation following approximately 90 arterial blood gas determinations over a 13-week...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Ontell SJ,Gauderer MW

    更新日期:1985-07-01 00:00:00