Abstract:
OBJECTIVES:We studied the usefulness of early dynamic (ED) and whole-body (WB) FDG-PET/CT for the evaluation of renal cell carcinoma (RCC). METHODS:One hundred patients with 107 tumours underwent kidney ED and WB FDG-PET/CT. We visually and semiquantitatively evaluated the FDG accumulation in RCCs in the ED and WB phases, and compared the accumulation values with regard to histological type (clear cell carcinoma [CCC] vs. non-clear cell carcinoma [N-CCC]), the TNM stage (high stage [3-4] vs. low stage [1-2]), the Fuhrman grade (high grade [3-4] vs. low grade [1-2]) and presence versus absence of venous (V) and lymphatic (Ly) invasion. RESULTS:In the ED phase, visual evaluation revealed no significant differences in FDG accumulation in terms of each item. However, the maximum standardized uptake value and tumour-to-normal tissue ratios were significantly higher in the CCCs compared to the N-CCCs (p < 0.001). In the WB phase, in contrast, significantly higher FDG accumulation (p < 0.001) was found in RCCs with a higher TNM stage, higher Furman grade, and the presence of V and Ly invasion in both the visual and the semiquantitative evaluations. CONCLUSIONS:ED and WB FDG-PET/CT is a useful tool for the evaluation of RCCs. KEY POINTS:• ED and WB FDG-PET/ CT helps to assess patients with RCC • ED FDG-PET/CT enabled differentiation between CCC and N-CCC • FDG accumulation in the WB phase reflects tumour aggressiveness • Management of RCC is improved by ED and WB FDG-PET/CT.
journal_name
Eur Radioljournal_title
European radiologyauthors
Nakajima R,Abe K,Kondo T,Tanabe K,Sakai Sdoi
10.1007/s00330-015-4026-3subject
Has Abstractpub_date
2016-06-01 00:00:00pages
1852-62issue
6eissn
0938-7994issn
1432-1084pii
10.1007/s00330-015-4026-3journal_volume
26pub_type
杂志文章abstract:OBJECTIVE:The aim of the study was to assess the performance and diagnostic value of a dual energy CT approach to reduce metal artefacts in subjects with metallic implants. METHODS:31 patients were examined in the area of their metallic implants using a dual energy CT protocol (filtered 140 kVp and 100 kVp spectrum, t...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s00330-011-2062-1
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journal_title:European radiology
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journal_title:European radiology
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journal_title:European radiology
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doi:
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