Investigation of a Salmonellosis Outbreak Caused by Multidrug Resistant Salmonella Typhimurium in China.

Abstract:

:The rapid emergence of multidrug resistant Salmonella is a global public-health concern as outbreaks in recent years have mostly been caused by multidrug resistant strains. Here, we evaluated an outbreak in China caused by multidrug resistant Salmonella enterica serovar Typhimurium (S. Typhimurium) by employing an epidemiological and laboratory investigation using conventional methods and whole genome sequencing (WGS). Eleven of the 12 people who participated in a banquet showed gastrointestinal symptoms, and 8S. Typhimurium strains were recovered. Isolated outbreak strains showed multidrug resistance (MDR), and decreased susceptibility to ciprofloxacin, a first-line drug recommended by WHO for clinical treatment of intestinal infections. Antimicrobial resistance (AMR) gene analysis indicated that the MDR phenotype of these outbreak strains may be due to the presence of a number of AMR genes, including the blaOXA-1 and blaTEM-1 β-lactamase genes, which are often plasmid-borne and easily transferred. Further virulence gene analysis indicated that these outbreak strains also carried a large number of virulence genes, including 2 types of Salmonella pathogenicity islands (SPI-1 and SPI-2) and many adhesion-related virulence genes. Cluster analysis based on pulse-field gel electrophoresis data and phylogenetic analysis based on WGS revealed that the outbreak clone was closely related to and thus probably derived from local strains. This outbreak caused by multidrug resistant S. Typhimurium highlights the need for government improved strategies for the prevention and control of Salmonella infections.

journal_name

Front Microbiol

authors

Xiang Y,Li F,Dong N,Tian S,Zhang H,Du X,Zhou X,Xu X,Yang H,Xie J,Yang C,Liu H,Qiu S,Song H,Sun Y

doi

10.3389/fmicb.2020.00801

subject

Has Abstract

pub_date

2020-04-29 00:00:00

pages

801

issn

1664-302X

journal_volume

11

pub_type

杂志文章
  • Genetics of Acquired Antibiotic Resistance Genes in Proteus spp.

    abstract::Proteus spp. are commensal Enterobacterales of the human digestive tract. At the same time, P. mirabilis is commonly involved in urinary tract infections (UTI). P. mirabilis is naturally resistant to several antibiotics including colistin and shows reduced susceptibility to imipenem. However higher levels of resistanc...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章,评审

    doi:10.3389/fmicb.2020.00256

    authors: Girlich D,Bonnin RA,Dortet L,Naas T

    更新日期:2020-02-21 00:00:00

  • The Water Microbiome Through a Pilot Scale Advanced Treatment Facility for Direct Potable Reuse.

    abstract::Advanced treatment facilities for potable water reuse of wastewater are designed to achieve high removal levels of specific pathogens, as well as many other constituents. However, changes to the microbial community throughout treatment, storage, and distribution of this water have not been well characterized. We appli...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2019.00993

    authors: Kantor RS,Miller SE,Nelson KL

    更新日期:2019-05-08 00:00:00

  • A Novel Derivative of (-)mycousnine Produced by the Endophytic Fungus Mycosphaerella nawae, Exhibits High and Selective Immunosuppressive Activity on T Cells.

    abstract::An endophytic fungus, Mycosphaerella nawae ZJLQ129, was isolated from the leaves of the traditional Chinese medicine Smilax china. From the fermentation broth and mycelium, a dibenzofurane compound (-)mycousnine (1) was isolated. Chemical modification of it to the amide derivative (-)mycousnine enamine (2), which is n...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2017.01251

    authors: Wang LW,Wang JL,Chen J,Chen JJ,Shen JW,Feng XX,Kubicek CP,Lin FC,Zhang CL,Chen FY

    更新日期:2017-07-05 00:00:00

  • Enzymatic Bioweathering and Metal Mobilization From Black Slate by the Basidiomycete Schizophyllum commune.

    abstract::Schizophyllum commune is a filamentous basidiomycete causing white-rot in many wood species with the help of a broad range of enzymes including multicopper oxidases such as laccases and laccase-like oxidases. Since these enzymes exhibit a broad substrate range, their ability to oxidatively degrade black slate was inve...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2018.02545

    authors: Kirtzel J,Madhavan S,Wielsch N,Blinne A,Hupfer Y,Linde J,Krause K,Svatoš A,Kothe E

    更新日期:2018-10-24 00:00:00

  • Biosurveillance of avian influenza and Newcastle disease viruses in the Barda region of Azerbaijan using real time RT-PCR and hemagglutination inhibition.

    abstract::The Azerbaijan State Veterinary Control Service (SVCS) has conducted active serological surveillance for avian influenza (AI) in poultry since 2006, when the first outbreak of AI H5N1 occurred in Azerbaijan. Samples are collected from September to May annually and tested using a hemagglutination inhibition (HI) assay ...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2015.01128

    authors: Zeynalova S,Guliyev F,Vatani M,Abbasov B

    更新日期:2015-11-06 00:00:00

  • The Anti-mycobacterial Activity of a Diterpenoid-Like Molecule Operates Through Nitrogen and Amino Acid Starvation.

    abstract::A library of 14 minimally cytotoxic diterpenoid-like compounds (CC50 > 70 μM on HepG2 human liver cells) was screened against Mycobacterium smegmatis, Staphylococcus aureus, and Escherichia coli to determine antimicrobial activity. Some compounds with a phenethyl alcohol (PE) core substituted with a β-cyclocitral deri...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2019.01444

    authors: Crusco A,Baptista R,Bhowmick S,Beckmann M,Mur LAJ,Westwell AD,Hoffmann KF

    更新日期:2019-06-25 00:00:00

  • Selection of Competitive and Efficient Rhizobia Strains for White Clover.

    abstract::The practice of inoculating forage legumes with rhizobia strains is widespread. It is assumed that the inoculated strain determines the performance of the symbiosis and nitrogen fixation rates. However, native-naturalized strains can be competitive, and actual nodule occupancy is often scarcely investigated. In conseq...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2019.00768

    authors: Irisarri P,Cardozo G,Tartaglia C,Reyno R,Gutiérrez P,Lattanzi FA,Rebuffo M,Monza J

    更新日期:2019-04-23 00:00:00

  • Anti-microfouling Activity of Glycomyces sediminimaris UTMC 2460 on Dominant Fouling Bacteria of Iran Marine Habitats.

    abstract::Discovery of environmentally safe anti-fouling agent is currently of considerable interest, due to the continuous impact of biofoulers on the marine habitats and the adverse effects of biocides on the environment. This study reports the anti-adhesion effect of marine living Actinobacteria against fouling strains isola...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2018.03148

    authors: Heidarian S,Mohammadipanah F,Maghsoudlou A,Dashti Y,Challis GL

    更新日期:2019-01-09 00:00:00

  • A Metabolic Trade-Off Modulates Policing of Social Cheaters in Populations of Pseudomonas aeruginosa.

    abstract::Pseudomonas aeruginosa uses quorum sensing (QS) to regulate the production of public goods such as the secreted protease elastase. P. aeruginosa requires the LasI-LasR QS circuit to induce elastase and enable growth on casein as the sole carbon and energy source. The LasI-LasR system also induces a second QS circuit, ...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2018.00337

    authors: Yan H,Wang M,Sun F,Dandekar AA,Shen D,Li N

    更新日期:2018-02-27 00:00:00

  • Resistance Breeding of Common Bean Shapes the Physiology of the Rhizosphere Microbiome.

    abstract::The taxonomically diverse rhizosphere microbiome contributes to plant nutrition, growth and health, including protection against soil-borne pathogens. We previously showed that breeding for Fusarium-resistance in common bean changed the rhizosphere microbiome composition and functioning. Here, we assessed the impact o...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2019.02252

    authors: Mendes LW,de Chaves MG,Fonseca MC,Mendes R,Raaijmakers JM,Tsai SM

    更新日期:2019-10-01 00:00:00

  • A TetR-Family Protein (CAETHG_0459) Activates Transcription From a New Promoter Motif Associated With Essential Genes for Autotrophic Growth in Acetogens.

    abstract::Acetogens can fix carbon (CO or CO2) into acetyl-CoA via the Wood-Ljungdahl pathway (WLP) that also makes them attractive cell factories for the production of fuels and chemicals from waste feedstocks. Although most biochemical details of the WLP are well understood and systems-level characterization of acetogen metab...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2019.02549

    authors: de Souza Pinto Lemgruber R,Valgepea K,Gonzalez Garcia RA,de Bakker C,Palfreyman RW,Tappel R,Köpke M,Simpson SD,Nielsen LK,Marcellin E

    更新日期:2019-11-15 00:00:00

  • Alkyl Protocatechuate-Loaded Nanostructured Lipid Systems as a Treatment Strategy for Paracoccidioides brasiliensis and Paracoccidioides lutzii In Vitro.

    abstract::Dodecyl protocatechuate (dodecyl) is a derivative of protocatechuic acid (3,4-dihydroxybenzoic acid) that possesses anti-oxidant and antifungal properties. Nanostructured lipid systems (NLS) can potentiate the action of many antifungal agents, reducing the required dose and side effects by improving their activity. Th...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2017.01048

    authors: Medina-Alarcón KP,Singulani JL,Voltan AR,Sardi JCO,Petrônio MS,Santos MB,Polaquini CR,Regasini LO,Bolzani VS,da Silva DHS,Chorilli M,Mendes-Giannini MJS,Fusco-Almeida AM

    更新日期:2017-06-12 00:00:00

  • Challenging Oil Bioremediation at Deep-Sea Hydrostatic Pressure.

    abstract::The Deepwater Horizon accident has brought oil contamination of deep-sea environments to worldwide attention. The risk for new deep-sea spills is not expected to decrease in the future, as political pressure mounts to access deep-water fossil reserves, and poorly tested technologies are used to access oil. This also a...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章,评审

    doi:10.3389/fmicb.2016.01203

    authors: Scoma A,Yakimov MM,Boon N

    更新日期:2016-08-03 00:00:00

  • Separating the Empirical Wheat From the Pseudoscientific Chaff: A Critical Review of the Literature Surrounding Glyphosate, Dysbiosis and Wheat-Sensitivity.

    abstract::The prevalence of digestive disorders has increased globally, as countries have adopted a more "Westernized" diet pattern. A Western diet, characterized as high in fat and refined carbohydrates, can also be defined as a product of increased technology and industrialization. Modern farmers rely on agrochemicals to meet...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章,评审

    doi:10.3389/fmicb.2020.556729

    authors: Barnett JA,Gibson DL

    更新日期:2020-09-25 00:00:00

  • Assessing Population Diversity of Brettanomyces Yeast Species and Identification of Strains for Brewing Applications.

    abstract::Brettanomyces yeasts have gained popularity in many sectors of the biotechnological industry, specifically in the field of beer production, but also in wine and ethanol production. Their unique properties enable Brettanomyces to outcompete conventional brewer's yeast in industrially relevant traits such as production ...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2020.00637

    authors: Colomer MS,Chailyan A,Fennessy RT,Olsson KF,Johnsen L,Solodovnikova N,Forster J

    更新日期:2020-04-09 00:00:00

  • Bacterioplankton Dynamics within a Large Anthropogenically Impacted Urban Estuary.

    abstract::The abundant and diverse microorganisms that inhabit aquatic systems are both determinants and indicators of aquatic health, providing essential ecosystem services such as nutrient cycling but also causing harmful blooms and disease in impacted habitats. Estuaries are among the most urbanized coastal ecosystems and as...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2015.01438

    authors: Jeffries TC,Schmitz Fontes ML,Harrison DP,Van-Dongen-Vogels V,Eyre BD,Ralph PJ,Seymour JR

    更新日期:2016-01-26 00:00:00

  • The Impact of the Antimicrobial Compounds Produced by Lactic Acid Bacteria on the Growth Performance of Mycobacterium avium subsp. paratuberculosis.

    abstract::Cell-free supernatants (CFSs) extracted from various lactic acid bacteria (LAB) cultures were applied to Mycobacterium avium subsp. paratuberculosis (MAP) cells to determine their effect on MAP viability. In addition, 5% lactic acid (LA; pH 3) and commercially synthetized nisin bacteriocin were also tested. This proce...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2018.00638

    authors: Kralik P,Babak V,Dziedzinska R

    更新日期:2018-04-03 00:00:00

  • Intestinal Short Chain Fatty Acids and their Link with Diet and Human Health.

    abstract::The colon is inhabited by a dense population of microorganisms, the so-called "gut microbiota," able to ferment carbohydrates and proteins that escape absorption in the small intestine during digestion. This microbiota produces a wide range of metabolites, including short chain fatty acids (SCFA). These compounds are ...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章,评审

    doi:10.3389/fmicb.2016.00185

    authors: Ríos-Covián D,Ruas-Madiedo P,Margolles A,Gueimonde M,de Los Reyes-Gavilán CG,Salazar N

    更新日期:2016-02-17 00:00:00

  • Antibiotic Resistance Genes and Bacterial Communities of Farmed Rainbow Trout Fillets (Oncorhynchus mykiss).

    abstract::The rise of antibiotic resistance is not only a challenge for human and animal health treatments, but is also posing the risk of spreading among bacterial populations in foodstuffs. Farmed fish-related foodstuffs, the food of animal origin most consumed worldwide, are suspected to be a reservoir of antibiotic resistan...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2020.590902

    authors: Helsens N,Calvez S,Prevost H,Bouju-Albert A,Maillet A,Rossero A,Hurtaud-Pessel D,Zagorec M,Magras C

    更新日期:2020-12-03 00:00:00

  • Diversity and role of plasmids in adaptation of bacteria inhabiting the Lubin copper mine in Poland, an environment rich in heavy metals.

    abstract::The Lubin underground mine, is one of three mining divisions in the Lubin-Glogow Copper District in Lower Silesia province (Poland). It is the source of polymetallic ore that is rich in copper, silver and several heavy metals. Black shale is also significantly enriched in fossil organic matter in the form of long-chai...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2015.00152

    authors: Dziewit L,Pyzik A,Szuplewska M,Matlakowska R,Mielnicki S,Wibberg D,Schlüter A,Pühler A,Bartosik D

    更新日期:2015-03-03 00:00:00

  • Characterization of Tail Sheath Protein of N4-Like Phage phiAxp-3.

    abstract::Achromobacter phage phiAxp-3, an N4-like bacteriophage, specifically recognize Achromobacter xylosoxidans lipopolysaccharide (LPS) as its receptor. PhiAxp-3 tail sheath protein (TSP, ORF69) shares 54% amino acid sequence identity with the TSP of phage N4 (gp65); the latter functions as a receptor binding protein and i...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2018.00450

    authors: Zhang Z,Tian C,Zhao J,Chen X,Wei X,Li H,Lin W,Feng R,Jiang A,Yang W,Yuan J,Zhao X

    更新日期:2018-03-15 00:00:00

  • Metatranscriptomic and functional metagenomic analysis of methylphosphonate utilization by marine bacteria.

    abstract::Aerobic degradation of methylphosphonate (MPn) by marine bacterioplankton has been hypothesized to contribute significantly to the ocean's methane supersaturation, yet little is known about MPn utilization by marine microbes. To identify the microbial taxa and metabolic functions associated with MPn-driven methane pro...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2013.00340

    authors: Martínez A,Ventouras LA,Wilson ST,Karl DM,Delong EF

    更新日期:2013-11-26 00:00:00

  • Surfactants tailored by the class Actinobacteria.

    abstract::Globally the change towards the establishment of a bio-based economy has resulted in an increased need for bio-based applications. This, in turn, has served as a driving force for the discovery and application of novel biosurfactants. The class Actinobacteria represents a vast group of microorganisms with the ability ...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章,评审

    doi:10.3389/fmicb.2015.00212

    authors: Kügler JH,Le Roes-Hill M,Syldatk C,Hausmann R

    更新日期:2015-03-19 00:00:00

  • Modeling the Inactivation of Intestinal Pathogenic Escherichia coli O157:H7 and Uropathogenic E. coli in Ground Chicken by High Pressure Processing and Thymol.

    abstract::Disease causing Escherichia coli commonly found in meat and poultry include intestinal pathogenic E. coli (iPEC) as well as extraintestinal types such as the Uropathogenic E. coli (UPEC). In this study we compared the resistance of iPEC (O157:H7) to UPEC in chicken meat using High Pressure Processing (HPP) in with (th...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2016.00920

    authors: Chien SY,Sheen S,Sommers CH,Sheen LY

    更新日期:2016-06-14 00:00:00

  • Distinct Expression Levels of ALS, LIP, and SAP Genes in Candida tropicalis with Diverse Virulent Activities.

    abstract::Candia tropicalis is an increasingly important human pathogen, causing nosocomial fungemia among patients with neutropenia or malignancy. However, limited research has been published concerning its pathogenicity. Based on the phenotypes of C. tropicalis in our previous study, we selected nine representative strains wi...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2016.01175

    authors: Yu S,Li W,Liu X,Che J,Wu Y,Lu J

    更新日期:2016-07-29 00:00:00

  • Characterization of IncC Plasmids in Enterobacterales of Food-Producing Animals Originating From China.

    abstract::Incompatibility group C (IncC) plasmids have received attention due to their broad host range and because they harbor key antibiotic resistance genes. Because these resistance genes can spread from food-producing animals to human, the proliferation of these plasmids represents a public health risk. In this study, a to...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2020.580960

    authors: Zhang Y,Lei CW,Chen X,Yao TG,Yu JW,Hu WL,Mao X,Wang HN

    更新日期:2020-10-27 00:00:00

  • Role of Ezrin Phosphorylation in HIV-1 Replication.

    abstract::Host-cell expression of the ezrin protein is required for CXCR4 (X4)-tropic HIV-1 infection. Ezrin function is regulated by phosphorylation at threonine-567. This study investigates the role of ezrin phosphorylation in HIV-1 infection and virion release. We analyzed the effects of ezrin mutations involving substitutio...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2018.01912

    authors: Kamiyama H,Izumida M,Umemura Y,Hayashi H,Matsuyama T,Kubo Y

    更新日期:2018-08-27 00:00:00

  • Qualitative and quantitative proteomic analysis of Vitamin C induced changes in Mycobacterium smegmatis.

    abstract::Vitamin C is a critical dietary nutrient in human which has a wide range of regulatory effects on gene expression and physiology of Mycobacterium tuberculosis that leads to a dormant drug-tolerant phenotype. In the presence of iron, vitamin C shows a high bactericidal activity even in the drug resistant phenotype of M...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2015.00451

    authors: Mishra A,Sarkar D

    更新日期:2015-05-18 00:00:00

  • FPR2: A Novel Promising Target for the Treatment of Influenza.

    abstract::The Formyl-peptide receptor-2 (FPR2) is a seven transmembrane G protein-coupled receptor, which plays an important role in sensing of bacteria and modulation of immune responses. FPR2 is also used by viruses for their own profit. Annexin A1, one of the multiple ligands of FPR2, is incorporated in the budding virus mem...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章,评审

    doi:10.3389/fmicb.2017.01719

    authors: Alessi MC,Cenac N,Si-Tahar M,Riteau B

    更新日期:2017-09-05 00:00:00

  • Immune Protection of Rhoptry Protein 21 (ROP21) of Toxoplasma gondii as a DNA Vaccine Against Toxoplasmosis.

    abstract::Toxoplasma gondii rhoptry proteins (TgROPs) are the major targets as key molecules for immunodiagnosis as well as immunoprophylaxis because of their initial presentation to the host immune system. In this work, it was aimed at evaluating the protection effect of TgROP21 DNA vaccine on experimental mice subjected to T....

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2018.00909

    authors: Zhang Z,Li Y,Wang M,Xie Q,Li P,Zuo S,Kong L,Wang C,Wang S

    更新日期:2018-05-08 00:00:00