Intestinal Short Chain Fatty Acids and their Link with Diet and Human Health.

Abstract:

:The colon is inhabited by a dense population of microorganisms, the so-called "gut microbiota," able to ferment carbohydrates and proteins that escape absorption in the small intestine during digestion. This microbiota produces a wide range of metabolites, including short chain fatty acids (SCFA). These compounds are absorbed in the large bowel and are defined as 1-6 carbon volatile fatty acids which can present straight or branched-chain conformation. Their production is influenced by the pattern of food intake and diet-mediated changes in the gut microbiota. SCFA have distinct physiological effects: they contribute to shaping the gut environment, influence the physiology of the colon, they can be used as energy sources by host cells and the intestinal microbiota and they also participate in different host-signaling mechanisms. We summarize the current knowledge about the production of SCFA, including bacterial cross-feedings interactions, and the biological properties of these metabolites with impact on the human health.

journal_name

Front Microbiol

authors

Ríos-Covián D,Ruas-Madiedo P,Margolles A,Gueimonde M,de Los Reyes-Gavilán CG,Salazar N

doi

10.3389/fmicb.2016.00185

subject

Has Abstract

pub_date

2016-02-17 00:00:00

pages

185

issn

1664-302X

journal_volume

7

pub_type

杂志文章,评审
  • Characterization of Novel Reassortant Influenza A (H5N2) Viruses Isolated from Poultry in Eastern China, 2015.

    abstract::Recently, novel variants of H5 highly pathogenic avian influenza viruses (AIVs) have been frequently isolated from poultry and wild birds in Asia, Europe and North America. Live poultry markets (LPMs) play an important role in the dissemination of influenza viruses. Four H5N2 AIVs were isolated from poultry during sur...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2017.00741

    authors: Wu H,Lu R,Peng X,Peng X,Cheng L,Liu F,Wu N

    更新日期:2017-04-25 00:00:00

  • Fecal Microbiota Characterization of Seychelles Giant Tortoises (Aldabrachelys gigantea) Living in Both Wild and Controlled Environments.

    abstract::A microbiome is defined as a complex collection of microorganisms and their genetic material. Studies regarding gut microbiomes of different animals have provided ecological and evolutionary information showing a strong link between health and disease. Very few studies have compared the gut microbiota of animals house...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2020.569249

    authors: Sandri C,Correa F,Spiezio C,Trevisi P,Luise D,Modesto M,Remy S,Muzungaile MM,Checcucci A,Zaborra CA,Mattarelli P

    更新日期:2020-10-20 00:00:00

  • Molecular Detection of Azole-Resistant Aspergillus fumigatus in Clinical Samples.

    abstract::Aspergillus diseases are often caused by Aspergillus fumigatus. Azoles are the mainstay of therapy, but the management of aspergillosis is hampered by the emergence of azole resistance. Rapid detection of azole resistance might benefit treatment outcome by early treatment modifications. However, the yield of fungal cu...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章,评审

    doi:10.3389/fmicb.2018.00515

    authors: Buil JB,Zoll J,Verweij PE,Melchers WJG

    更新日期:2018-03-21 00:00:00

  • Transcriptional Regulation of the Type VI Secretion System 1 Genes by Quorum Sensing and ToxR in Vibrio parahaemolyticus.

    abstract::Vibrio parahaemolyticus, the leading cause of seafood-associated gastroenteritis, harbors two separate T6SSs on chromosomes 1 and 2, i.e., T6SS1 (VP1386-1420) and T6SS2 (VPA1025-1046). T6SS1 contains at least 7 putative operons: VP1386-1387, VP1388-1390, VP1392-1391, VP1393-1406, VP1400-1406, VP1409-1407, and VP1410-1...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2017.02005

    authors: Zhang Y,Gao H,Osei-Adjei G,Zhang Y,Yang W,Yang H,Yin Z,Huang X,Zhou D

    更新日期:2017-10-16 00:00:00

  • Soil Microbiome Is More Heterogeneous in Organic Than in Conventional Farming System.

    abstract::Organic farming system and sustainable management of soil pathogens aim at reducing the use of agricultural chemicals in order to improve ecosystem health. Despite the essential role of microbial communities in agro-ecosystems, we still have limited understanding of the complex response of microbial diversity and comp...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2016.02064

    authors: Lupatini M,Korthals GW,de Hollander M,Janssens TK,Kuramae EE

    更新日期:2017-01-04 00:00:00

  • Utilization of Host-Derived Glycans by Intestinal Lactobacillus and Bifidobacterium Species.

    abstract::Members of the genus Lactobacillus are commonly found at the gastrointestinal tract and other mucosal surfaces of humans. This genus includes various species with a great number of potentially probiotic bacteria. Other often-used probiotic species belong to Bifidobacterium, a genus almost exclusively associated with t...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章,评审

    doi:10.3389/fmicb.2018.01917

    authors: Zúñiga M,Monedero V,Yebra MJ

    更新日期:2018-08-17 00:00:00

  • Isolation of new Brazilian giant viruses from environmental samples using a panel of protozoa.

    abstract::The Megavirales are a newly described order capable of infecting different types of eukaryotic hosts. For the most part, the natural host is unknown. Several methods have been used to detect these viruses, with large discrepancies between molecular methods and co-cultures. To isolate giant viruses, we propose the use ...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2015.01086

    authors: Dornas FP,Khalil JY,Pagnier I,Raoult D,Abrahão J,La Scola B

    更新日期:2015-10-06 00:00:00

  • Assessing Population Diversity of Brettanomyces Yeast Species and Identification of Strains for Brewing Applications.

    abstract::Brettanomyces yeasts have gained popularity in many sectors of the biotechnological industry, specifically in the field of beer production, but also in wine and ethanol production. Their unique properties enable Brettanomyces to outcompete conventional brewer's yeast in industrially relevant traits such as production ...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2020.00637

    authors: Colomer MS,Chailyan A,Fennessy RT,Olsson KF,Johnsen L,Solodovnikova N,Forster J

    更新日期:2020-04-09 00:00:00

  • To the Land and Beyond: Crab Microbiomes as a Paradigm for the Evolution of Terrestrialization.

    abstract::The transition to terrestrial environments by formerly aquatic species has occurred repeatedly in many animal phyla and lead to the vast diversity of extant terrestrial species. The differences between aquatic and terrestrial habitats are enormous and involved remarkable morphological and physiological changes. Conver...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章,评审

    doi:10.3389/fmicb.2020.575372

    authors: Cannicci S,Fratini S,Meriggi N,Bacci G,Iannucci A,Mengoni A,Cavalieri D

    更新日期:2020-10-07 00:00:00

  • Time-Resolved Transcriptomics and Constraint-Based Modeling Identify System-Level Metabolic Features and Overexpression Targets to Increase Spiramycin Production in Streptomyces ambofaciens.

    abstract::In this study we have applied an integrated system biology approach to characterize the metabolic landscape of Streptomyces ambofaciens and to identify a list of potential metabolic engineering targets for the overproduction of the secondary metabolites in this microorganism. We focused on an often overlooked growth p...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2017.00835

    authors: Fondi M,Pinatel E,Talà A,Damiano F,Consolandi C,Mattorre B,Fico D,Testini M,De Benedetto GE,Siculella L,De Bellis G,Alifano P,Peano C

    更新日期:2017-05-12 00:00:00

  • Modeling the Inactivation of Intestinal Pathogenic Escherichia coli O157:H7 and Uropathogenic E. coli in Ground Chicken by High Pressure Processing and Thymol.

    abstract::Disease causing Escherichia coli commonly found in meat and poultry include intestinal pathogenic E. coli (iPEC) as well as extraintestinal types such as the Uropathogenic E. coli (UPEC). In this study we compared the resistance of iPEC (O157:H7) to UPEC in chicken meat using High Pressure Processing (HPP) in with (th...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2016.00920

    authors: Chien SY,Sheen S,Sommers CH,Sheen LY

    更新日期:2016-06-14 00:00:00

  • Effects of Recombinant Toxoplasma gondii Citrate Synthase I on the Cellular Functions of Murine Macrophages In vitro.

    abstract::Toxoplasmosis, which is one of the most widespread zoonoses worldwide, has a high incidence and infection can result in severe disease in humans and livestock. Citrate synthase (CS) is a component of nearly all living cells that plays a vital role in the citric acid cycle, which is the central metabolic pathway of aer...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2017.01376

    authors: Liu X,Ma Q,Sun X,Lu M,Ehsan M,Hasan MW,Xu L,Yan R,Song X,Li X

    更新日期:2017-07-21 00:00:00

  • Experimental Evolution as an Underutilized Tool for Studying Beneficial Animal-Microbe Interactions.

    abstract::Microorganisms play a significant role in the evolution and functioning of the eukaryotes with which they interact. Much of our understanding of beneficial host-microbe interactions stems from studying already established associations; we often infer the genotypic and environmental conditions that led to the existing ...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章,评审

    doi:10.3389/fmicb.2016.01444

    authors: Hoang KL,Morran LT,Gerardo NM

    更新日期:2016-09-13 00:00:00

  • Different Genetic Sources Contribute to the Small RNA Population in the Arbuscular Mycorrhizal Fungus Gigaspora margarita.

    abstract::RNA interference (RNAi) is a key regulatory pathway of gene expression in almost all eukaryotes. This mechanism relies on short non-coding RNA molecules (sRNAs) to recognize in a sequence-specific manner DNA or RNA targets leading to transcriptional or post-transcriptional gene silencing. To date, the fundamental role...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2020.00395

    authors: Silvestri A,Turina M,Fiorilli V,Miozzi L,Venice F,Bonfante P,Lanfranco L

    更新日期:2020-03-13 00:00:00

  • Exopolysaccharides From Streptococcus thermophilus ST538 Modulate the Antiviral Innate Immune Response in Porcine Intestinal Epitheliocytes.

    abstract::It was reported that exopolysaccharides (EPSs) from lactobacilli are able to differentially modulate mucosal antiviral immunity. Although research has described the ability of EPSs derived from Streptococcus thermophilus to modulate the mucosal immune system, their impact on antiviral immunity was less explored. In th...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2020.00894

    authors: Mizuno H,Tomotsune K,Islam MA,Funabashi R,Albarracin L,Ikeda-Ohtsubo W,Aso H,Takahashi H,Kimura K,Villena J,Sasaki Y,Kitazawa H

    更新日期:2020-05-19 00:00:00

  • Effects of Peptide Thanatin on the Growth and Transcriptome of Penicillium digitatum.

    abstract::Penicillium digitatum is the most damaging pathogen provoking green mold in citrus fruit during storage, and there is an urgent need for novel antifungal agents with high efficiency. The aim of this study was to investigate the antifungal effects of peptide thanatin against P. digitatum and the molecular mechanisms. R...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2020.606482

    authors: Feng G,Li X,Wang W,Deng L,Zeng K

    更新日期:2020-12-14 00:00:00

  • Evaluation of Recombinant Multi-Epitope Outer Membrane Protein-Based Klebsiella pneumoniae Subunit Vaccine in Mouse Model.

    abstract::Safety and protective efficacy of recombinant multi-epitope subunit vaccine (r-AK36) was evaluated in a mouse model. Recombinant AK36 protein comprised of immunodominant antigens from outer membrane proteins (Omp's) of Klebsiella pneumoniae namely OmpA and OmpK36. r-AK36 was highly immunogenic and the hyperimmune sera...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2017.01805

    authors: Babu L,Uppalapati SR,Sripathy MH,Reddy PN

    更新日期:2017-09-20 00:00:00

  • Perspectives on Functional Red Mold Rice: Functional Ingredients, Production, and Application.

    abstract::Monacolin K (MK) is a secondary metabolite of the Monascus species that can inhibit cholesterol synthesis. Functional red mold rice (FRMR) is the fermentation product of Monascus spp., which is rich in MK. FRMR is usually employed to regulate serum cholesterol, especially for hypercholesterolemic patients who refuse s...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2020.606959

    authors: Yanli F,Xiang Y

    更新日期:2020-11-25 00:00:00

  • One Health Approach Reveals the Absence of Methicillin-Resistant Staphylococcus aureus in Autochthonous Cattle and Their Environments.

    abstract::Antimicrobial resistance represents one of the greatest challenges of the twenty-first century, and it is globally recognized that addressing this problem requires a concerted One Health approach involving humans, animals, and the environment. Methicillin-resistant Staphylococcus aureus (MRSA) currently represents a g...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2019.02735

    authors: Correia S,Silva V,García-Díez J,Teixeira P,Pimenta K,Pereira JE,Oliveira S,Rocha J,Manaia CM,Igrejas G,Poeta P

    更新日期:2019-12-18 00:00:00

  • Identification of New Degrons in Streptococcus mutans Reveals a Novel Strategy for Engineering Targeted, Controllable Proteolysis.

    abstract::Recently, controllable, targeted proteolysis has emerged as one of the most promising new strategies to study essential genes and otherwise toxic mutations. One of the principal limitations preventing the wider adoption of this approach is due to the lack of easily identifiable species-specific degrons that can be use...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2017.02572

    authors: Liu N,Chaudhry MT,Xie Z,Kreth J,Merritt J

    更新日期:2017-12-19 00:00:00

  • Molecular Analysis of S-morphology Aflatoxin Producers From the United States Reveals Previously Unknown Diversity and Two New Taxa.

    abstract::Aflatoxins are highly toxic carcinogens that detrimentally influence profitability of agriculture and the health of humans and domestic animals. Several phylogenetically distinct fungi within Aspergillus section Flavi have S-morphology (average sclerotial size < 400 μm), and consistently produce high concentrations of...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2020.01236

    authors: Singh P,Callicott KA,Orbach MJ,Cotty PJ

    更新日期:2020-06-11 00:00:00

  • Cross-Talk between the Aeromonas hydrophila Type III Secretion System and Lateral Flagella System.

    abstract::Aeromonas hydrophila is responsible for aeromonad septicaemia in fish, and gastroenteritis and wound infections in humans. The type III secretion system (T3SS) is utilized by aeromonads to inject protein effectors directly into host cells. One of the major genetic regulators of the T3SS in several bacterial species is...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2016.01434

    authors: Zhao YH,Shaw JG

    更新日期:2016-09-07 00:00:00

  • The Microbiome of an Active Meat Curing Brine.

    abstract::Traditional food products are important to our culture and heritage, and to the continued success of the food industry. Many of the production processes associated with these products have not been subjected to an in-depth microbial compositional analysis. The traditional process of curing meat, both preserves a natur...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2018.03346

    authors: Woods DF,Kozak IM,Flynn S,O'Gara F

    更新日期:2019-01-11 00:00:00

  • Novel Widespread Marine Oomycetes Parasitising Diatoms, Including the Toxic Genus Pseudo-nitzschia: Genetic, Morphological, and Ecological Characterisation.

    abstract::Parasites are key drivers of phytoplankton bloom dynamics and related aquatic ecosystem processes. Yet, the dearth of morphological and molecular information hinders the assessment of their diversity and ecological role. Using single-cell techniques, we characterise morphologically and molecularly, intracellular paras...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2018.02918

    authors: Garvetto A,Nézan E,Badis Y,Bilien G,Arce P,Bresnan E,Gachon CMM,Siano R

    更新日期:2018-12-03 00:00:00

  • Global Distribution of Anaerobic Ammonia Oxidation (Anammox) Bacteria - Field Surveys in Wetland, Dryland, Groundwater Aquifer and Snow.

    abstract::The discovery of anaerobic ammonia oxidation (anammox) expanded our knowledge on the microbial nitrogen cycle. Previous studies report that anammox bacteria are distributed in a wide range of habitats and plays significant roles in the global nitrogen cycle. However, most studies focus only on individual ecosystems or...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2019.02583

    authors: Wang Y,Xu L,Wang S,Ye F,Zhu G

    更新日期:2019-11-12 00:00:00

  • From Petri Dish to Patient: Bioavailability Estimation and Mechanism of Action for Antimicrobial and Immunomodulatory Natural Products.

    abstract::The new era of multidrug resistance of pathogens against frontline antibiotics has compromised the immense therapeutic gains of the 'golden age,' stimulating a resurgence in antimicrobial research focused on antimicrobial and immunomodulatory components of botanical, fungal or microbial origin. While much valuable inf...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章,评审

    doi:10.3389/fmicb.2019.02470

    authors: Sadgrove NJ,Jones GL

    更新日期:2019-10-31 00:00:00

  • AmrZ and FleQ Co-regulate Cellulose Production in Pseudomonas syringae pv. Tomato DC3000.

    abstract::Pseudomonas syringae pv. tomato DC3000 carries the wssABCDEFGHI operon for the synthesis of acetylated cellulose, whose production is stimulated by increasing the intracellular levels of the second messenger c-di-GMP. This enhances air-liquid biofilm formation and generates a wrinkly colony morphotype in solid media. ...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2019.00746

    authors: Pérez-Mendoza D,Felipe A,Ferreiro MD,Sanjuán J,Gallegos MT

    更新日期:2019-04-17 00:00:00

  • Grapevine leafroll-associated virus 3.

    abstract::Grapevine leafroll disease (GLD) is one of the most important grapevine viral diseases affecting grapevines worldwide. The impact on vine health, crop yield, and quality is difficult to assess due to a high number of variables, but significant economic losses are consistently reported over the lifespan of a vineyard i...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2013.00082

    authors: Maree HJ,Almeida RP,Bester R,Chooi KM,Cohen D,Dolja VV,Fuchs MF,Golino DA,Jooste AE,Martelli GP,Naidu RA,Rowhani A,Saldarelli P,Burger JT

    更新日期:2013-04-16 00:00:00

  • HIV-1 gp120 and morphine induced oxidative stress: role in cell cycle regulation.

    abstract::HIV infection and illicit drugs are known to induce oxidative stress and linked with severity of viral replication, disease progression, impaired cell cycle regulation and neurodegeneration. Studies have shown that morphine accelerates HIV infection and disease progression mediated by Reactive oxygen species (ROS). Ox...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2015.00614

    authors: Samikkannu T,Ranjith D,Rao KV,Atluri VS,Pimentel E,El-Hage N,Nair MP

    更新日期:2015-06-23 00:00:00

  • Aspergillus fumigatus-Related Species in Clinical Practice.

    abstract::Aspergillus fumigatus is the main etiologic agent of invasive aspergillosis (IA). Other Aspergillus species belonging to the section Fumigati (A. fumigatus complex) may occasionally be the cause of IA. These strains are often misidentified, as they cannot be distinguished from A. fumigatus by conventional morphologica...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章,评审

    doi:10.3389/fmicb.2016.00683

    authors: Lamoth F

    更新日期:2016-05-17 00:00:00