Abstract：
PURPOSE:To determine the incidence of postintubation hypotension (PIH) and associated outcomes in critically ill patients requiring endotracheal intubation. MATERIALS AND METHODS:Medical records were reviewed for 479 consecutive critically ill adult patients who required intubation by an intensive care unit (ICU) service at 1 of 4 academic tertiary care hospitals. The primary outcome measure was the incidence of PIH. Secondary outcome measures included mortality, ICU length of stay, requirement for renal replacement therapy, and a composite end point consisting of overall mortality, ICU length of stay greater than 14 days, duration of mechanical ventilation longer than 7 days, and renal replacement therapy requirement. RESULTS:Overall, the incidence of PIH among ICU patients requiring intubation was 46% (218/479 patients). On univariate analysis, patients who developed PIH had increased ICU mortality (37% PIH vs 28% no PIH, P = .049) and overall mortality (39% PIH vs 30% no PIH, P = .045). After adjusting for important risk factors, development of PIH was associated with the composite end point of major morbidity and mortality (odds ratio, 2.00; 95% confidence interval, 1.30-3.07; P = .0017). CONCLUSIONS:The development of PIH is common in ICU patients requiring emergency airway control and is associated with poor patient outcomes.
journal_name
J Crit Carejournal_title
Journal of critical careauthors
Green RS,Turgeon AF,McIntyre LA,Fox-Robichaud AE,Fergusson DA,Doucette S,Butler MB,Erdogan M,Canadian Critical Care Trials Group (CCCTG).doi
10.1016/j.jcrc.2015.06.007subject
Has Abstractpub_date
2015-10-01 00:00:00pages
1055-60issue
5eissn
0883-9441issn
1557-8615pii
S0883-9441(15)00349-4journal_volume
30pub_type
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