Abstract:
PURPOSE:Automated weaning modes are available in some mechanical ventilators, but no studies compared them hitherto. We compared the performance of 3 automated modes under standard and challenging situations. METHODS:We used a lung simulator to compare 3 automated modes, adaptive support ventilation (ASV), mandatory rate ventilation (MRV), and Smartcare, in 6 situations, weaning success, weaning failure, weaning success with extreme anxiety, weaning success with Cheyne-Stokes, weaning success with irregular breathing, and weaning failure with ineffective efforts. RESULTS:The 3 modes correctly recognized the situations of weaning success and failure, even when anxiety or irregular breathing were present but incorrectly recognized weaning success with Cheyne-Stokes. MRV incorrectly recognized weaning failure with ineffective efforts. Time to pressure support (PS) stabilization was shorter for ASV (1-2 minutes for all situations) and MRV (1-7 minutes) than for Smartcare (8-78 minutes). ASV had higher rates of PS oscillations per 5 minutes (4-15), compared with Smartcare (0-1) and MRV (0-12), except when extreme anxiety was present. CONCLUSIONS:Smartcare, ASV, and MRV were equally able to recognize weaning success and failure, despite the presence of anxiety or irregular breathing but performed incorrectly in the presence of Cheyne-Stokes. PS behavior over the time differs among modes, with ASV showing larger and more frequent PS oscillations over the time. Clinical studies are needed to confirm our results.
journal_name
J Crit Carejournal_title
Journal of critical careauthors
Morato JB,Sakuma MT,Ferreira JC,Caruso Pdoi
10.1016/j.jcrc.2011.12.021subject
Has Abstractpub_date
2012-12-01 00:00:00pages
741.e1-8issue
6eissn
0883-9441issn
1557-8615pii
S0883-9441(12)00009-3journal_volume
27pub_type
杂志文章abstract:PURPOSE:Urinary excretion of chloride corrects metabolic acidosis, but this may be hampered in patients with impaired renal function. We explored the effects of renal function on acid-base characteristics and urinary strong ion excretion using the Stewart approach in critically ill patients with metabolic acidosis. MA...
journal_title:Journal of critical care
pub_type: 杂志文章
doi:10.1016/j.jcrc.2011.05.028
更新日期:2012-06-01 00:00:00
abstract:PURPOSE:To determine the efficiency of noninvasive mechanical ventilation (NIV) both in protection from intubation and in preventing reintubation of postextubation in patients in the pediatric intensive care unit (PICU). METHODS:A prospective observational study was conducted in a multidisciplinary 10-bed tertiary PIC...
journal_title:Journal of critical care
pub_type: 杂志文章
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更新日期:2016-04-01 00:00:00
abstract:PURPOSE:To investigate the impact of delay in rapid response call (RRC) activation on Hospital mortality. MATERIALS AND METHODS:This study was conducted in a university affiliated hospital providing medical, surgical, mental health, maternity, and pediatric services. RRCs were considered delayed if RRC activation was ...
journal_title:Journal of critical care
pub_type: 杂志文章
doi:10.1016/j.jcrc.2017.05.006
更新日期:2017-10-01 00:00:00
abstract::This paper focuses on the use of data from an electronic medical record (EMR) within a multi-facility health care organization. It describes how health provider workflow is enhanced by extracting data from multiple sources in a near real-time fashion and presenting it to the user in ways that are unavailable in the el...
journal_title:Journal of critical care
pub_type: 杂志文章
doi:10.1016/j.jcrc.2004.09.003
更新日期:2004-12-01 00:00:00
abstract:PURPOSE:To determine the cost-effectiveness of implementing a point-of-care (POC) Lactate Program in the emergency department (ED) for patients with suspected sepsis to identify patients who can benefit from early resuscitation. MATERIALS AND METHODS:We constructed a cost-effectiveness model to examine an ED with 30 0...
journal_title:Journal of critical care
pub_type: 杂志文章
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更新日期:2016-12-01 00:00:00
abstract:OBJECTIVE:To describe perceptions of the administrative procedures for seasonal bed closures and their consequences in the intensive care unit (ICU), and to critique this example of health care priority setting for legitimacy and fairness. DESIGN:A qualitative study using case study methods and interviews with key par...
journal_title:Journal of critical care
pub_type: 杂志文章
doi:10.1053/jcrc.2003.YJCRC6
更新日期:2003-03-01 00:00:00
abstract:PURPOSE:The primary objective of this survey was to describe pharmacists' attitudes regarding probiotic use in the intensive care unit (ICU); secondary objectives were to evaluate pharmacists' knowledge and use of probiotics for critically ill patients. METHODS:The survey instrument was rigorously designed and pretest...
journal_title:Journal of critical care
pub_type: 杂志文章
doi:10.1016/j.jcrc.2015.10.016
更新日期:2016-02-01 00:00:00
abstract:PURPOSE:A volume challenge is useful for determining whether cardiac output will respond to further volume loading by the Frank-Starling mechanism. To properly test this mechanism, there must be an increase in right atrial pressure (Pra) but this requires variable amounts of normal saline. The purpose of this study was...
journal_title:Journal of critical care
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0883-9441(99)90030-8
更新日期:1999-12-01 00:00:00
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journal_title:Journal of critical care
pub_type: 杂志文章
doi:10.1016/s0883-9441(97)90021-6
更新日期:1997-03-01 00:00:00
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journal_title:Journal of critical care
pub_type: 杂志文章
doi:10.1016/j.jcrc.2008.08.012
更新日期:2009-09-01 00:00:00
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journal_title:Journal of critical care
pub_type: 杂志文章
doi:10.1016/j.jcrc.2016.10.008
更新日期:2017-04-01 00:00:00
abstract::Cell-free circulating DNA (cf-DNA) can be detected by various of laboratory techniques. We described a branched DNA-based Alu assay for measuring cf-DNA in septic patients. Compared to healthy controls and systemic inflammatory response syndrome (SIRS) patients, serum cf-DNA levels were significantly higher in septic ...
journal_title:Journal of critical care
pub_type: 杂志文章
doi:10.1016/j.jcrc.2015.10.013
更新日期:2016-02-01 00:00:00
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journal_title:Journal of critical care
pub_type: 杂志文章
doi:10.1016/s0883-9441(96)90016-7
更新日期:1996-03-01 00:00:00
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journal_title:Journal of critical care
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更新日期:2017-02-01 00:00:00
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journal_title:Journal of critical care
pub_type: 杂志文章
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更新日期:2020-04-01 00:00:00
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journal_title:Journal of critical care
pub_type: 杂志文章
doi:10.1016/j.jcrc.2019.08.017
更新日期:2019-12-01 00:00:00
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journal_title:Journal of critical care
pub_type: 杂志文章,评审
doi:10.1016/s0883-9441(96)90024-6
更新日期:1996-06-01 00:00:00
abstract:PURPOSE:To identify early mortality-associated clinical risk factors preceding, during, and after cardiac surgery in children. MATERIALS AND METHODS:Of the 722 children admitted to our pediatric intensive care unit (PICU) from January 1992 to January 1997 after repair of congenital heart defects, 70 required 48 hours ...
journal_title:Journal of critical care
pub_type: 杂志文章
doi:10.1053/jcrc.2002.36760
更新日期:2002-12-01 00:00:00
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journal_title:Journal of critical care
pub_type: 杂志文章
doi:10.1016/s0883-9441(97)90040-x
更新日期:1997-09-01 00:00:00
abstract:PURPOSE:To assess the clinical significance of serial troponin I levels (measured in the first 72 hours from admission) in 42 consecutive patients with moderate-to-severe acute respiratory distress syndrome (ARDS). Echocardiography and electrocardiogram testings were serially performed in the time window. MATERIALS AN...
journal_title:Journal of critical care
pub_type: 杂志文章
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更新日期:2016-06-01 00:00:00
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journal_title:Journal of critical care
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jcrc.2017.04.023
更新日期:2017-08-01 00:00:00
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journal_title:Journal of critical care
pub_type: 杂志文章
doi:10.1016/j.jcrc.2008.03.036
更新日期:2009-06-01 00:00:00
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journal_title:Journal of critical care
pub_type: 杂志文章
doi:10.1016/j.jcrc.2018.11.020
更新日期:2019-04-01 00:00:00
abstract:PURPOSE:The prognosis of allogeneic hematopoietic stem cell transplantation (HSCT) patients admitted to the intensive care unit (ICU) is still poor. Overall, when these patients receive reduced intensity conditioning (RIC) regimens, the survival is better. To date, no study has specifically evaluated the outcome of RIC...
journal_title:Journal of critical care
pub_type: 杂志文章
doi:10.1016/j.jcrc.2015.06.020
更新日期:2015-10-01 00:00:00
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journal_title:Journal of critical care
pub_type: 杂志文章
doi:10.1016/j.jcrc.2011.07.084
更新日期:2012-06-01 00:00:00
abstract:PURPOSE:Current guidelines for traumatic brain injury (TBI) recommend antiepileptic drugs (AEDs) for 7 days after injury to decrease posttraumatic seizure risk. Phenytoin decreases seizure risk 73% vs placebo during this time. Levetiracetam (LEV) is an alternative; however, no published data validate comparable efficac...
journal_title:Journal of critical care
pub_type: 杂志文章
doi:10.1016/j.jcrc.2012.11.020
更新日期:2013-10-01 00:00:00
abstract:PURPOSE:Sepsis is a lethal outcome of the inflammation and coagulation process. Human interleukin (IL)-6 and tumor necrosis factor (TNF) α are well-known inflammation factors closely associated with sepsis. In the present study, we aim to investigate the association of promoter-region polymorphisms IL-6 (-174G/C) rs180...
journal_title:Journal of critical care
pub_type: 杂志文章
doi:10.1016/j.jcrc.2015.04.123
更新日期:2015-10-01 00:00:00
abstract:PURPOSE:To determine the incidence of postintubation hypotension (PIH) and associated outcomes in critically ill patients requiring endotracheal intubation. MATERIALS AND METHODS:Medical records were reviewed for 479 consecutive critically ill adult patients who required intubation by an intensive care unit (ICU) serv...
journal_title:Journal of critical care
pub_type: 杂志文章,多中心研究
doi:10.1016/j.jcrc.2015.06.007
更新日期:2015-10-01 00:00:00
abstract:PURPOSE:To study the effects of systemic inflammatory response syndrome (SIRS) on polymorhonuclear neutrophil (PMN) function and phenotype by comparing neutrophils from critically ill patients with SIRS against those from healthy blood donors. MATERIAL AND METHODS:Intensive care unit patients (n = 110) who met at leas...
journal_title:Journal of critical care
pub_type: 杂志文章
doi:10.1016/j.jcrc.2007.09.004
更新日期:2008-12-01 00:00:00
abstract:PURPOSE:The objective of this study is to correlate the levels of satisfaction of family members, with their perception of the way information was offered and assistance delivered during the patient's stay in the intensive care unit (ICU). MATERIALS AND METHODS:This is a prospective study conducted in a 13-bed mixed I...
journal_title:Journal of critical care
pub_type: 杂志文章
doi:10.1016/j.jcrc.2007.04.004
更新日期:2008-09-01 00:00:00