Abstract：
BACKGROUND:Pulmonary embolism (PE) is a significant cause of morbidity and mortality in patients with spinal cord injury (SCI). Prophylactic anticoagulation is associated with a reduction in mortality rates, but there is limited evidence regarding the incidence rate of PE following cessation of anticoagulation after the first 3 months of injury. STUDY DESIGN:Single-centre retrospective study. OBJECTIVE:To estimate the incidence rate of PE after 90 days of SCI. SETTING:The National Spinal Injuries Centre at Stoke Mandeville Hospital, Aylesbury, UK. METHODS:The study includes 640 new-onset SCI patients. All computer tomography pulmonary angiograms (CTPAs) or ventilation-perfusion lung scans between 2008 and 2013 were identified. Medical notes and scans were reviewed and clinical outcomes and radiological findings were recorded. RESULTS:A total of 91 patients with a new-onset SCI had a CTPA or a perfusion lung scan. PE was detected in a total of 8 patients. The incidence of PE was 1.25%; 95% confidence interval (0.39-2.11) over a 6-year period. The duration of injury at the time of PE was 7 months. CONCLUSION:The incidence rate of PE post 3 months of SCI remains significant, though much lower than immediately post injury.
journal_name
Spinal Cordjournal_title
Spinal cordauthors
Alabed S,de Heredia LL,Naidoo A,Belci M,Hughes RJ,Meagher TMdoi
10.1038/sc.2015.105subject
Has Abstractpub_date
2015-11-01 00:00:00pages
835-7issue
11eissn
1362-4393issn
1476-5624pii
sc2015105journal_volume
53pub_type
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