Abstract：
:The human adult adrenal cortex is composed of the zona glomerulosa (zG), zona fasciculata (zF), and zona reticularis (zR), which are responsible for production of mineralocorticoids, glucocorticoids, and adrenal androgens, respectively. The final completion of cortical zonation in humans does not occur until puberty with the establishment of the zR and its production of adrenal androgens; a process called adrenarche. The maintenance of the adrenal cortex involves the centripetal displacement and differentiation of peripheral Sonic hedgehog-positive progenitors cells into zG cells that later transition to zF cells and subsequently zR cells.
journal_name
Endocrinol Metab Clin North Amjournal_title
Endocrinology and metabolism clinics of North Americaauthors
Xing Y,Lerario AM,Rainey W,Hammer GDdoi
10.1016/j.ecl.2015.02.001subject
Has Abstractpub_date
2015-06-01 00:00:00pages
243-74issue
2eissn
0889-8529issn
1558-4410pii
S0889-8529(15)00002-Xjournal_volume
44pub_type
杂志文章,评审abstract：:This article describes the basic skills for the design, implementation, and interpretation of randomized controlled studies. Strengths and limitations of each study design are discussed. Epidemiologic issues in the analysis and interpretation of studies, such as loss to follow-up and biases, are included. Numerous cli...
journal_title：Endocrinology and metabolism clinics of North America
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abstract：:Endocrinologists may be challenged not only by the great diversity of rare heritable metabolic bone diseases, but also by an unusual array of genetically transmitted skeletal dysplasias. The striking impact that many such skeletal dysplasias have on bone leads physicians naturally to question whether there is a metabo...
journal_title：Endocrinology and metabolism clinics of North America
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journal_title：Endocrinology and metabolism clinics of North America
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doi：
更新日期：1988-06-01 00:00:00
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journal_title：Endocrinology and metabolism clinics of North America
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journal_title：Endocrinology and metabolism clinics of North America
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journal_title：Endocrinology and metabolism clinics of North America
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journal_title：Endocrinology and metabolism clinics of North America
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journal_title：Endocrinology and metabolism clinics of North America
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journal_title：Endocrinology and metabolism clinics of North America
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journal_title：Endocrinology and metabolism clinics of North America
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journal_title：Endocrinology and metabolism clinics of North America
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journal_title：Endocrinology and metabolism clinics of North America
pub_type： 杂志文章,评审
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journal_title：Endocrinology and metabolism clinics of North America
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journal_title：Endocrinology and metabolism clinics of North America
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journal_title：Endocrinology and metabolism clinics of North America
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journal_title：Endocrinology and metabolism clinics of North America
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journal_title：Endocrinology and metabolism clinics of North America
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journal_title：Endocrinology and metabolism clinics of North America
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journal_title：Endocrinology and metabolism clinics of North America
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journal_title：Endocrinology and metabolism clinics of North America
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journal_title：Endocrinology and metabolism clinics of North America
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journal_title：Endocrinology and metabolism clinics of North America
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journal_title：Endocrinology and metabolism clinics of North America
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journal_title：Endocrinology and metabolism clinics of North America
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doi：
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journal_title：Endocrinology and metabolism clinics of North America
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journal_title：Endocrinology and metabolism clinics of North America
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journal_title：Endocrinology and metabolism clinics of North America
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journal_title：Endocrinology and metabolism clinics of North America
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abstract：:A number of morphologic and physiologic changes accompany pregnancy such as an increase in lactotrophs and prolactin production, and a decrease in gonadotropins and GH. The hormonal milieu can affect patients with prolactinomas, especially macroadenomas, to cause an increase in size in a minority of patients. Complica...
journal_title：Endocrinology and metabolism clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1995-03-01 00:00:00
