Epidemiology and outcomes of acute encephalitis.

abstract：PURPOSE OF REVIEW:To describe the background, principles and implementation of the Stroke Action Plan for Europe 2018--2030 (SAP-E) in the perspective of the current COVID-19 pandemic. RECENT FINDINGS:SAP-E sets targets for the implementation of evidence-based preventive actions and stroke services to 2030. A recent m...

journal_title：Current opinion in neurology

authors： Christensen H,Pezzella FR,Action Plan for Stroke in Europe Implementation Steering Committee.

更新日期：2021-02-01 00:00:00

abstract：:This paper reviews clinical reports of various movement disorders (dystonia, chorea, ballism and parkinsonism) caused by well defined lesions of the putamen, globus pallidus, substantia nigra, thalamus and subthalamus. The role of basal ganglia in motor control is also emphasized. ...

journal_title：Current opinion in neurology

authors： Berardelli A

更新日期：1995-08-01 00:00:00

abstract：:Dermatomyositis and polymyositis are treatable disorders of skeletal muscle. Despite their clinical similarities, they appear to have fundamentally different autoimmune origins. Inclusion body myositis, from its origins 30 years ago, has emerged as the commonest acquired myopathy of the elderly. Despite inflammatory c...

journal_title：Current opinion in neurology

authors： Hilton-Jones D

更新日期：2001-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Despite the extensive research carried out in the past decades, the current pathophysiological notions of neurodegenerative disease as well as effective treatments to reduce their progression are largely unknown. Alterations of the human microbiota, the plethora of different microscopic organisms that...

journal_title：Current opinion in neurology

authors： Marizzoni M,Provasi S,Cattaneo A,Frisoni GB

更新日期：2017-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Frontotemporal dementia (FTD) is a clinically, pathologically and genetically heterogeneous disorder. Mutations in a number of genes are associated with FTD, although until recently only two [progranulin (GRN) and microtubule-associated protein tau (MAPT)] were known to be major causes of the disease....

journal_title：Current opinion in neurology

authors： Rohrer JD,Warren JD

更新日期：2011-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim of this study was to assess the seizure manifestations and risk of epilepsy in encephalitis associated with antibodies against neuronal cell-surface (autoimmune encephalitis) or myelin-associated antigens, and to review several chronic epileptic disorders, including Rasmussen's encephalitis, f...

journal_title：Current opinion in neurology

authors： Spatola M,Dalmau J

更新日期：2017-06-01 00:00:00

abstract：PURPOSE OF REVIEW:This review summarizes the recent studies assessing patients with psychogenic nonepileptic seizures and developments in treatment. RECENT FINDINGS:The misdiagnosis of nonepileptic seizure is costly to patients, the healthcare system, and to society. Patients with nonepileptic seizures are prescribed ...

journal_title：Current opinion in neurology

authors： LaFrance WC Jr

更新日期：2008-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Recent terminations of clinical trials of myostatin inhibitors in muscular dystrophy have raised questions about the predictiveness of mouse models for this therapeutic strategy. RECENT FINDINGS:A variety of myostatin inhibitors have been developed for preclinical and clinical studies. These inhibito...

journal_title：Current opinion in neurology

authors： Wagner KR

更新日期：2020-10-01 00:00:00

abstract：PURPOSE OF REVIEW:The development of successful myelin repair strategies depends on the detailed knowledge of the cellular and molecular processes underlying demyelination and remyelination in the central nervous system of animal models and in patients with multiple sclerosis (MS). Based on the complexity of the demyel...

journal_title：Current opinion in neurology

authors： Gallo V,Armstrong RC

更新日期：2008-06-01 00:00:00

abstract：PURPOSE OF REVIEW:We present an overview of recent concepts in mechanisms underlying cognitive decline associated with brain aging and neurodegeneration from the perspective of MRI. RECENT FINDINGS:Recent findings challenge the established link between neuroimaging biomarkers of neurodegeneration and age-related or di...

journal_title：Current opinion in neurology

authors： Draganski B,Lutti A,Kherif F

更新日期：2013-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The aims of this article are to review emerging therapies for multiple sclerosis (MS) and to consider new approaches to assessment and achievement of treatment success in patients with this disease. RECENT FINDINGS:A number of disease-modifying therapies for MS, including oral agents, are in advanced...

journal_title：Current opinion in neurology

authors： Fox EJ,Rhoades RW

更新日期：2012-02-01 00:00:00

abstract：:Neural circuits comprised of dopamine-containing and dopamine-receptive neurons are altered functionally after the repeated intermittent administration of cocaine and its withdrawal. The characterization of these neuroadaptive changes at various times after repeated exposure to cocaine is important because they may re...

journal_title：Current opinion in neurology

authors： Pilotte NS

更新日期：1997-12-01 00:00:00

abstract：:A review of the literature on methods of seizure or epilepsy severity assessments resulted in tabulation of the seizure rating scales known as US Department of Veterans Affairs (VA), Chalfont-National Hospital, Liverpool, Hague, and others. Each of the scales reviewed has some advantages, but none of them appears to b...

journal_title：Current opinion in neurology

authors： Cramer JA

更新日期：2001-04-01 00:00:00

abstract：:Three genetic loci for Alzheimer's disease have been identified. These are the amyloid precursor gene on chromosome 21, a gene for early-onset autosomal dominant Alzheimer's disease on chromosome 14, and the risk-modifying gene APOE on chromosome 19. Additional Alzheimer's disease genes remain to be found. The genes i...

journal_title：Current opinion in neurology

authors： Schellenberg GD

更新日期：1995-08-01 00:00:00

abstract：PURPOSE OF REVIEW:To summarize clinical key points, diagnostic features, and results of imaging and therapy of spinal dural arteriovenous fistula (SDAVF). RECENT FINDINGS:SDAVF accounts for 70% of spinal arteriovenous malformation with an annual incidence of 5-10 cases per million. At least 80% of patients are male, a...

journal_title：Current opinion in neurology

authors： Koch C

更新日期：2006-02-01 00:00:00

abstract：PURPOSE OF REVIEW:This review summarizes the major recent developments in understanding of pathogenic mechanisms in inflammatory and paraproteinaemic neuropathies. RECENT FINDINGS:In the inflammatory neuropathies, there has been a particular focus on antibody-mediated disease affecting the nodal/paranodal regions. Dis...

journal_title：Current opinion in neurology

authors： Rinaldi S,Bennett DL

更新日期：2014-10-01 00:00:00

abstract：PURPOSE OF REVIEW:To review recent developments in the application of stem cells for transplantation therapies in neurodegenerative diseases. RECENT FINDINGS:Stem cell transplantation has the potential to improve function by replacing cells lost to the disease and reconstructing elements of neural circuitry or by prov...

journal_title：Current opinion in neurology

authors： Rosser AE,Zietlow R,Dunnett SB

更新日期：2007-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Cognitive impairments are common in children with epilepsy. They may already be present before the onset of epilepsy or occur - and even progress - during its course. Many variables contribute to cognitive dysfunction. Those that can be targeted to prevent (further) cognitive impairment will be highli...

journal_title：Current opinion in neurology

authors： Braun KP

更新日期：2017-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Here we discuss recent advances regarding the molecular genetic basis of dominantly inherited ataxias. RECENT FINDINGS:Important recent observations include insights into the mechanisms by which expanded polyglutamine causes cerebellar degeneration; new findings regarding how noncoding expansions may...

journal_title：Current opinion in neurology

authors： Soong BW,Paulson HL

更新日期：2007-08-01 00:00:00

abstract：PURPOSE OF REVIEW:The last 5 years have seen the number of ultra-high field (UHF; 7 T and beyond) MRI scanners nearly double. Benefits include improved specificity, better sensitivity for signal-starved compounds, and the ability to detect, quantify, and monitor tumor activity and treatment effects. This is especially ...

journal_title：Current opinion in neurology

authors： Lupo JM,Li Y,Hess CP,Nelson SJ

更新日期：2011-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Stroke thrombolysis is in the process of moving from academic centers into community-based standard therapy in experienced centers. Recently published data on patient selection, imaging and other technical or organizational advances are reviewed in order to improve the safety and efficacy of stroke th...

journal_title：Current opinion in neurology

authors： Lindsberg PJ,Kaste M

更新日期：2003-02-01 00:00:00

abstract：PURPOSE OF REVIEW:For a long time, cognitive impairment in multiple sclerosis patients has been considered less important than, for instance, physical disability. This is no longer true because of the crucial role that cognitive deficits play in the good day-to-day adjustment of patients. This review highlights recent ...

journal_title：Current opinion in neurology

authors： Hoffmann S,Tittgemeyer M,von Cramon DY

更新日期：2007-06-01 00:00:00

abstract：PURPOSE OF REVIEW:This review highlights recent work using advanced imaging approaches that have improved our understanding of the underlying neural mechanisms associated with disrupted brain development or demonstrated the potential of MRI to provide objective biomarkers of cerebral injury that relate to subsequent ne...

journal_title：Current opinion in neurology

authors： Counsell SJ,Ball G,Edwards AD

更新日期：2014-04-01 00:00:00

abstract：PURPOSE OF REVIEW:The present review will outline neuroprotective and neurotoxic effects of central nervous system (CNS) infiltrating T cells during viral infections. Evidence demonstrating differential roles for antiviral effector and resident memory T-cell subsets in virologic control and immunopathology in the CNS w...

journal_title：Current opinion in neurology

authors： Ai S,Klein RS

更新日期：2020-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Although cluster headache has traditionally been thought of as a vascular headache disorder, its periodicity suggests an involvement of central areas such as the hypothalamus. This review covers the past 3 years, which have seen remarkable progress in understanding the pathophysiology of circadian hea...

journal_title：Current opinion in neurology

authors： May A,Leone M

更新日期：2003-06-01 00:00:00

abstract：PURPOSE OF REVIEW:A stroke mimic is a situation in which a diagnosis of stroke at admission is not confirmed, and a stroke chameleon is a situation in which a stroke is revealed by clinical symptoms that are not usual in stroke. The objective of this review is to identify the most frequent clinical situations in which ...

journal_title：Current opinion in neurology

authors： Moulin S,Leys D

更新日期：2019-02-01 00:00:00

abstract：PURPOSE OF REVIEW:This review presents the new terms and concepts proposed by the International League Against Epilepsy (ILAE) Classification Commission in 2010 to describe seizures and epilepsies. This is the first major revision in 21 years and reflects the rapid evolution in our understanding of the epilepsies. REC...

journal_title：Current opinion in neurology

authors： Korff CM,Scheffer IE

更新日期：2013-04-01 00:00:00

abstract：PURPOSE OF REVIEW:To describe the path of technological developments that have led to the actual application of MRI-guided focused ultrasound in multiple neurological disorders and to update the more recent technical advances in the field. An insight into the latest clinical achievements in movement disorders will be p...

journal_title：Current opinion in neurology

authors： Martínez-Fernández R,Pineda-Pardo JA

更新日期：2020-08-01 00:00:00

abstract：:Little progress has been made in the treatment outcome of patients with glioblastoma in the past 10 to 15 years, despite an aggressive multimodality regimen using surgery, radiation, and chemotherapy. New approaches, particularly molecular strategies, have become the clinicians' and scientists' hope for the future in ...

journal_title：Current opinion in neurology

authors： Yung WK

更新日期：1994-12-01 00:00:00

abstract：PURPOSE OF REVIEW:This review on traumatic brain injury consolidates the substantial current literature available on the pathophysiology, mechanisms, developments, and their subsequent effects on outcome. In particular, it tries to conceptualize why our greatly improved understanding of pathophysiology and neurobiology...

journal_title：Current opinion in neurology

authors： Nortje J,Menon DK

更新日期：2004-12-01 00:00:00