Stem cell transplantation for neurodegenerative diseases.

abstract：:Neuropharmacology is aiding our understanding of the control of eye movements in at least three ways. First, neurotransmitters have been identified in the pathways that coordinate gaze. Second, the technique of pharmacologic inactivation has provided a powerful method to determine the contributions of populations of n...

journal_title：Current opinion in neurology

authors： Leigh RJ,Ramat S

更新日期：1999-02-01 00:00:00

abstract：PURPOSE OF REVIEW:The aims of this article are to review emerging therapies for multiple sclerosis (MS) and to consider new approaches to assessment and achievement of treatment success in patients with this disease. RECENT FINDINGS:A number of disease-modifying therapies for MS, including oral agents, are in advanced...

journal_title：Current opinion in neurology

authors： Fox EJ,Rhoades RW

更新日期：2012-02-01 00:00:00

abstract：PURPOSE OF REVIEW:This review provides an overview of recent developments in diagnosis, pathophysiology, neuroimaging and management of functional (psychogenic) movement disorders (FMD). RECENT FINDINGS:There has been increasing interest to study the underlying pathophysiology of FMD, which has resulted in a broadened...

journal_title：Current opinion in neurology

authors： Czarnecki K,Hallett M

更新日期：2012-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Although cluster headache has traditionally been thought of as a vascular headache disorder, its periodicity suggests an involvement of central areas such as the hypothalamus. This review covers the past 3 years, which have seen remarkable progress in understanding the pathophysiology of circadian hea...

journal_title：Current opinion in neurology

authors： May A,Leone M

更新日期：2003-06-01 00:00:00

abstract：:An increasing number of mutations in the CACNA1A gene have been identified, which are associated with a broad clinical spectrum, including familial hemiplegic migraine. Transfection studies and mouse model analyses are currently being undertaken to study the correlation between CACNA1A mutations and disease. ...

journal_title：Current opinion in neurology

authors： Kors EE,van den Maagdenberg AM,Plomp JJ,Frants RR,Ferrari MD

更新日期：2002-06-01 00:00:00

abstract：:At the dawning of the present decade, deemed appropriately the Decade of the Spine, acute spinal cord injury lingers as a formidable disorder affecting society. The enormous physical, emotional and socioeconomic impact of acute spinal cord injury on society is well known. Consequently, intensive clinical and laborator...

journal_title：Current opinion in neurology

authors： Dumont AS,Dumont RJ,Oskouian RJ

更新日期：2002-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Trigeminal autonomic cephalgias (TACs) are characterized by frequent, short-lasting headache attacks with ipsilateral facial autonomic features. They include cluster headache, paroxysmal hemicrania, and short-lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing. The...

journal_title：Current opinion in neurology

authors： Wilbrink LA,Ferrari MD,Kruit MC,Haan J

更新日期：2009-06-01 00:00:00

abstract：:We currently conceive of a migraine attack as originating in the brain. Triggers of an attack initiate a depolarizing neuroelectric and metabolic event likened to the spreading depression of Leao. This event activates the headache and associated features of the attack by mechanisms that remain to be determined, but ap...

journal_title：Current opinion in neurology

authors： Aurora SK,Welch KM

更新日期：2000-06-01 00:00:00

abstract：PURPOSE OF REVIEW:The advent of novel techniques for tracing connections in vivo, such as diffusion tensor magnetic resonance imaging tractography, allows us, for the first time in the human brain, to study the microstructural integrity of white matter fibres and perform virtual dissections of large scale neurocognitiv...

journal_title：Current opinion in neurology

authors： Catani M

更新日期：2006-12-01 00:00:00

abstract：:Insight into the pathomechanisms of the benign positional vertigo syndromes has led to quick and effective treatment with positional manoeuvres. Our understanding of other causes of vertigo is progressing at a slower pace, but several recent findings regarding vestibular neuritis, vascular compression of the eighth ne...

journal_title：Current opinion in neurology

authors： Lempert T

更新日期：1998-02-01 00:00:00

abstract：PURPOSE OF REVIEW:For a long time, cognitive impairment in multiple sclerosis patients has been considered less important than, for instance, physical disability. This is no longer true because of the crucial role that cognitive deficits play in the good day-to-day adjustment of patients. This review highlights recent ...

journal_title：Current opinion in neurology

authors： Hoffmann S,Tittgemeyer M,von Cramon DY

更新日期：2007-06-01 00:00:00

abstract：:Slowly, advances are being made in the understanding and treatment of primary childhood brain tumors. The addition of chemotherapy has resulted in better survival for children with medulloblastoma. For other tumor types, therapeutic advances have been slower. High-dose chemotherapy is increasingly being employed to tr...

journal_title：Current opinion in neurology

authors： Packer RJ

更新日期：1997-12-01 00:00:00

abstract：PURPOSE OF REVIEW:To review the clinical findings, differential diagnosis, treatment and outcome of pseudotumoral demyelinating lesions including tumefactive demyelination and Baló's concentric sclerosis. RECENT FINDINGS:MRI findings, such as dynamic restricted diffusion changes at the edge of pseudotumoral lesions he...

journal_title：Current opinion in neurology

authors： Hardy TA

更新日期：2019-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Cerebral amyloid angiopathy (CAA) is diagnosed primarily as a cause of lobar intracerebral hemorrhages (ICH) in elderly patients. With improving MRI techniques, however, the role of CAA in causing other symptoms has become clear. Recognizing the full clinical spectrum of CAA is important for diagnosis...

journal_title：Current opinion in neurology

authors： Wermer MJH,Greenberg SM

更新日期：2018-02-01 00:00:00

abstract：PURPOSE OF REVIEW:This article reviews what is known about the health and well being of adults with cerebral palsy. It also addresses the factors known to affect the areas identified in the World Health Organization International Classification of Functioning model as being critical for optimal health and well being. ...

journal_title：Current opinion in neurology

authors： Liptak GS

更新日期：2008-04-01 00:00:00

abstract：PURPOSE OF REVIEW:This review will summarize new neuroimaging techniques, particularly MRI and PET imaging, that can be used to assess brain tumor growth and angiogenesis. RECENT FINDINGS:Glioma tumor vasculature is abnormal, and advances in MRI now permit visualization of the hemodynamic properties of gliomas includi...

journal_title：Current opinion in neurology

authors： Gerstner ER,Sorensen AG,Jain RK,Batchelor TT

更新日期：2008-12-01 00:00:00

abstract：PURPOSE OF REVIEW:We analyze recent data on technical aspects, clinical indications, and imaging features of spinal cord MRI in multiple sclerosis, and on the value of this examination for assessing the type and extension of spinal cord damage, and for predicting prognosis in patients with this disease. RECENT FINDING...

journal_title：Current opinion in neurology

authors： Rovira A,de Stefano N

更新日期：2016-08-01 00:00:00

abstract：PURPOSE OF REVIEW:This review on traumatic brain injury consolidates the substantial current literature available on the pathophysiology, mechanisms, developments, and their subsequent effects on outcome. In particular, it tries to conceptualize why our greatly improved understanding of pathophysiology and neurobiology...

journal_title：Current opinion in neurology

authors： Nortje J,Menon DK

更新日期：2004-12-01 00:00:00

abstract：PURPOSE OF REVIEW:To provide an update on the major advances in inflammatory myopathies. RECENT FINDINGS:Polymyositis is an uncommon disorder that can be misdiagnosed when the old, and never validated, criteria of Bohan and Peter are used. New diagnostic criteria were recently introduced, in which the MHC/CD8 complex ...

journal_title：Current opinion in neurology

authors： Dalakas MC

更新日期：2004-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Emery-Dreifuss muscular dystrophy (EDMD) is caused by mutations in EMD encoding emerin and LMNA encoding A-type lamins, proteins of the nuclear envelope. In the past decade, there has been an extraordinary burst of research on the nuclear envelope. Discoveries resulting from this basic research have i...

journal_title：Current opinion in neurology

authors： Muchir A,Worman HJ

更新日期：2019-10-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim is to systematically and critically review the relationship between migraine and estrogen, the predominant female sex hormone, with a focus on studies published in the last 18 months. RECENT FINDINGS:Recent functional MRI (fMRI) studies of the brain support the existence of anatomical and fun...

journal_title：Current opinion in neurology

authors： Chai NC,Peterlin BL,Calhoun AH

更新日期：2014-06-01 00:00:00

abstract：:The pathogenesis of primary vasculitides, which are assumed to have an autoimmune pathogenesis, is not well understood. The endothelial cell adhesion molecules seem to play an active role, which varies according to the histopathologic stage of vascular lesions. The role of genetic factors also seems quite important, a...

journal_title：Current opinion in neurology

authors： Said G

更新日期：1999-10-01 00:00:00

abstract：:A long series of studies beginning with the pioneering experiments of Wiesel and Hubel [1] has shown that correct visual experience is crucial for the development of the visual system. Recent results suggest that neurotrophic factors of the nerve growth factor family might have a relevant role in mediating the effects...

journal_title：Current opinion in neurology

authors： Pizzorusso T,Maffei L

更新日期：1996-04-01 00:00:00

abstract：PURPOSE OF REVIEW:The 2016 WHO classification of tumors of the central nervous system (2016 CNS WHO) features many changes that are relevant to neurologists treating patients with brain tumors as well as neurologists involved in basic, clinical, and epidemiological research. This review summarizes what neurologists nee...

journal_title：Current opinion in neurology

authors： DeWitt JC,Mock A,Louis DN

更新日期：2017-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim is to review recent publications on amyotrophic lateral sclerosis (ALS). RECENT FINDINGS:The Awaji recommendations for electrophysiological diagnosis will permit earlier clinical trials entry. The use of ultrasound to visualize fasciculations, even in deep muscles, will contribute to earlier ...

journal_title：Current opinion in neurology

authors： de Carvalho M,Swash M

更新日期：2011-10-01 00:00:00

abstract：PURPOSE OF REVIEW:This review presents the new terms and concepts proposed by the International League Against Epilepsy (ILAE) Classification Commission in 2010 to describe seizures and epilepsies. This is the first major revision in 21 years and reflects the rapid evolution in our understanding of the epilepsies. REC...

journal_title：Current opinion in neurology

authors： Korff CM,Scheffer IE

更新日期：2013-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Convergent evidence from a number of neuroscience disciplines supports the hypothesis that Alzheimer's disease and other neurodegenerative disorders progress along brain networks. This review considers the role of neuroimaging in strengthening the case for network-based neurodegeneration and elucidati...

journal_title：Current opinion in neurology

authors： Greicius MD,Kimmel DL

更新日期：2012-12-01 00:00:00

abstract：:In the past few years evidence that atherosclerotic disease of the aortic arch is probably an underestimate source of emboli, particularly moving thrombi in the lumen, has accumulated. Pathological studies, and more recently transesophageal echocardiographic studies, have shown that atherosclerotic disease of the aort...

journal_title：Current opinion in neurology

authors： Heinzlef O,Cohen A,Amarenco P

更新日期：1997-02-01 00:00:00

abstract：:Selected topics related to rehabilitation of individuals with spinal cord lesions are reviewed and commented upon. A 10-week arm-cranking programme improved aerobic capacity and endurance in tetraplegics. Furthermore, endurance training and forced vital capacity were found to be positively correlated. Rowing had addit...

journal_title：Current opinion in neurology

authors： Biering-Sørensen F,Hartkopp A

更新日期：1995-12-01 00:00:00

abstract：PURPOSE OF REVIEW:This review provides an update on our knowledge regarding prevention and management of medication overuse headache (MOH). RECENT FINDINGS:The prevalence of MOH is 1-2% in the general population worldwide, and because of the tremendous socio-economic cost, it is likely to be the most costly neurologic...

journal_title：Current opinion in neurology

authors： Russell MB,Lundqvist C

更新日期：2012-06-01 00:00:00