Vitamin A deficiency and pulmonary oxygen toxicity: morphometric studies in the murine lung.

abstract：:The copper concentrations in organs of developing Long-Evans Cinnamon (LEC) rats (2 d to 13 mo) were measured to elucidate the pathogenesis of their hereditary hepatitis. Hepatic copper contents of LEC rats were significantly higher than those of control rats (26 to 92 times higher). The subcellular distribution of he...

journal_title：Pediatric research

authors： Okayasu T,Tochimaru H,Hyuga T,Takahashi T,Takekoshi Y,Li Y,Togashi Y,Takeichi N,Kasai N,Arashima S

更新日期：1992-03-01 00:00:00

abstract：:To define respiratory effects of peripheral acidemia during early development, we injected lactic acid (LA) into the jugular vein of 32 1- to 7-d-old rabbit pups and four adult rabbits. The body weight of newborns varied between 67 +/- 17 g in 1-d-old and 119.8 +/- 33.7 g in 7-d-old animals versus 4 +/- 0.1 kg in adul...

journal_title：Pediatric research

authors： Ducros G,Trippenbach T

更新日期：1991-06-01 00:00:00

abstract：:Naloxone, a specific opiate antagonist with no agonist properties, in doses of 0.4 and 4.0 mg/kg was found to markedly reduce the duration of primary apnea in asphyxiated newborn rabbits. There was no effect on the duration of the hyperpneic phase (time to primary apnea) or on survival time (time to last gasp). It is ...

journal_title：Pediatric research

authors： Chernick V,Madansky DL,Lawson EE

更新日期：1980-04-01 00:00:00

abstract：:Newborn human infants, particularly those born prematurely, are susceptible to infection with a variety of microorganisms. We questioned whether limitations in the T cell repertoire contribute to the neonatal immunocompromised state. To describe developmental changes of the T cell repertoire, cDNA segments correspondi...

journal_title：Pediatric research

authors： Schelonka RL,Raaphorst FM,Infante D,Kraig E,Teale JM,Infante AJ

更新日期：1998-03-01 00:00:00

abstract：:Contributions from multidisciplinary investigations have focused attention on the potential of tissue engineering to yield novel therapeutics. Congenital malformations, including cleft palate, craniosynostosis, and craniofacial skeletal hypoplasias represent excellent targets for the implementation of tissue engineeri...

journal_title：Pediatric research

authors： Panetta NJ,Gupta DM,Slater BJ,Kwan MD,Liu KJ,Longaker MT

更新日期：2008-05-01 00:00:00

abstract：:This study tested the hypothesis that the sexually dimorphic adrenocortical response to stress is already established before birth. Chronically instrumented late gestation pregnant sheep carrying 16 male and 15 female age-matched singleton fetuses were subjected to an acute episode of hypoxic stress. Maternal and feta...

journal_title：Pediatric research

authors： Giussani DA,Fletcher AJ,Gardner DS

更新日期：2011-02-01 00:00:00

abstract：:This study was conducted to investigate myocardial excitation-contraction coupling in the fetus of the diabetic rabbit (FDM). On day 14 of gestation, diabetes was induced in pregnant rabbits by alloxan injection. On day 28 of gestation, mechanical function of the fetal myocardium was determined in the isolated arteria...

journal_title：Pediatric research

authors： Nakanishi T,Matsuoka S,Uemura S,Shimizu T,Nishioka K,Neufeld ND,Jarmakani JM

更新日期：1984-12-01 00:00:00

abstract：BACKGROUND:To systematically evaluate short-term efficacy of UCM versus other interventions in preterm infants. METHODS:Six engines were searched until February 2020 for randomized controlled trials (RCTs) assessing UCM versus immediate cord clamping (ICC), delayed cord clamping (DCC), or no intervention. Primary outc...

journal_title：Pediatric research

authors： Barboza JJ,Albitres-Flores L,Rivera-Meza M,Rodriguez-Huapaya J,Caballero-Alvarado J,Pasupuleti V,Hernandez AV

更新日期：2020-04-21 00:00:00

abstract：BACKGROUND:Bradycardia and oxygen desaturation episodes are common among preterm very low birth weight (VLBW) infants in the Neonatal Intensive Care Unit (NICU), and their association with adverse outcomes such as bronchopulmonary dysplasia (BPD) is unclear. METHODS:For 502 VLBW infants we quantified bradycardias (HR ...

journal_title：Pediatric research

authors： Fairchild KD,Nagraj VP,Sullivan BA,Moorman JR,Lake DE

更新日期：2019-06-01 00:00:00

abstract：:The interrelationship of 2,3-diphosphoglycerate (2,3-DPG) and P50 levels during the fetal and postnatal life were determined in two mammalian species which do not have a switchover of hemoglobin type at the end of their fetal development. In the guinea pig and rabbit, the 2,3-DPG levels remain low during fetal life an...

journal_title：Pediatric research

authors： Bard H,Shapiro M

更新日期：1979-03-01 00:00:00

abstract：:Clinical trials demonstrated decreasing rates of bronchopulmonary dysplasia in preterm infants with hypoxic respiratory failure treated with inhaled nitric oxide (iNO). However, the molecular and biochemical effects of iNO on developing human fetal lungs remain vastly unknown. By using a well-characterized model of hu...

journal_title：Pediatric research

authors： Johnston LC,Gonzales LW,Lightfoot RT,Guttentag SH,Ischiropoulos H

更新日期：2010-05-01 00:00:00

abstract：:Adverse perinatal events affecting cerebral functions are a major cause of neonatal mortality, morbidity, and long-term neurologic deficit. Intrapartum fetal EEG, which records fetal brain electrical activity, provides a monitoring modality for evaluating the fetal CNS during labor. In this study, we describe a new ap...

journal_title：Pediatric research

authors： Thaler I,Boldes R,Timor-Tritsch I

更新日期：2000-09-01 00:00:00

abstract：:Our goal for this study was to determine whether the maturation of fat absorption in neonatal life is functionally related to an increased ability to hydrolyze dietary fat, to absorb long-chain fatty acids, or to do both. In 16 preterm and in eight term neonates, the intestinal ability to hydrolyze triacylglycerols an...

journal_title：Pediatric research

authors： Rings EH,Minich DM,Vonk RJ,Stellaard F,Fetter WP,Verkade HJ

更新日期：2002-01-01 00:00:00

abstract：:Completely penetrant mutations in the surfactant protein B gene (SFTPB) and >75% reduction of SFTPB expression disrupt pulmonary surfactant function and cause neonatal respiratory distress syndrome. To inform studies of genetic regulation of SFTPB expression, we created a catalogue of SFTPB variants by comprehensive r...

journal_title：Pediatric research

authors： Hamvas A,Wegner DJ,Carlson CS,Bergmann KR,Trusgnich MA,Fulton L,Kasai Y,An P,Mardis ER,Wilson RK,Cole FS

更新日期：2007-08-01 00:00:00

abstract：:Active compression-decompression (ACD) cardiopulmonary resuscitation (CPR) with the inspiratory threshold valve (ITV) has been recently recommended by the American Heart Association for treatment of adults in cardiac arrest (class IIb: alternative, useful intervention), but this new technique has never been used in a ...

journal_title：Pediatric research

authors： Voelckel WG,Lurie KG,Sweeney M,McKnite S,Zielinski T,Lindstrom P,Peterson C,Wenzel V,Lindner KH

更新日期：2002-04-01 00:00:00

abstract：:We studied absorption of the potentially allergenic protein beta-lactoglobulin during acute rotavirus diarrhea in infants and assessed the relationship of this macromolecular absorption with intestinal sugar permeability. After oral rehydration, 38 patients with acute gastroenteritis were given orally a 100-ml solutio...

journal_title：Pediatric research

authors： Jalonen T,Isolauri E,Heyman M,Crain-Denoyelle AM,Sillanaukee P,Koivula T

更新日期：1991-09-01 00:00:00

abstract：:Time-corrected measurements of transplacental and transamniotic electrical potentials were made in potassium-deficient rats on the 20th day of gestation. These averaged 6.4 mV and 2.0 mV, respectively, in the deficient group as compared with 14.3 and 18.4, respectively, in the controls. The measured maternal potassium...

journal_title：Pediatric research

authors： Fantel AG

更新日期：1978-10-01 00:00:00

abstract：:Spontaneous preterm birth is a serious and common pregnancy complication associated with hormonal dysregulation, infection, inflammation, immunity, rupture of fetal membranes, stress, bleeding, and uterine distention. Heredity is 25-40% and mostly involves the maternal genome, with contribution of the fetal genome. Si...

journal_title：Pediatric research

authors： Hallman M,Haapalainen A,Huusko JM,Karjalainen MK,Zhang G,Muglia LJ,Rämet M

更新日期：2019-03-01 00:00:00

abstract：:Inhibition of Pseudomonas cepacia (but not Pseudomonas aeruginosa) by beta-lactams was decreased in 5% CO2 in air compared with air alone. The effect of CO2 and pH (range, 6.0 to 8.0) on beta-lactam susceptibility, beta-lactamase expression, and outer membrane proteins was studied in isolates recovered from the sputum...

journal_title：Pediatric research

authors： Corkill JE,Deveney J,Pratt J,Shears P,Smyth A,Heaf D,Hart CA

更新日期：1994-03-01 00:00:00

abstract：:This study investigated the effects of intraventricular/periventricular blood on cerebral cAMP production and cortical cerebrovascular reactivity. Under halothane and N2O anesthesia, 3 mL of either autologous blood or artificial cerebrospinal fluid (CSF) were injected into the left caudate nucleus; volume was adequate...

journal_title：Pediatric research

authors： Pourcyrous M,Parfenova H,Shibata M,Bada HS,Korones SB,Leffler CW

更新日期：1997-09-01 00:00:00

abstract：BACKGROUND:Toll-like receptor (TLR)-mediated inflammation may contribute to neonatal sepsis, for which pentoxifylline (PTX), a phosphodiesterase inhibitor that raises intracellular cAMP, is a candidate adjunctive therapy. We characterized the anti-inflammatory effects of PTX toward TLR-mediated production of inflammato...

journal_title：Pediatric research

authors： Speer EM,Dowling DJ,Ozog LS,Xu J,Yang J,Kennady G,Levy O

更新日期：2017-05-01 00:00:00

abstract：:Based on the serum phenylalanine levels under free diet patients with hyperphenylalaninemia are classified as "classical" (>1200 micromol/L), "mild" (600-1200 micromol/L), or "non-phenylketonuria (PKU)-hyperphenylalaninemia" (<600 micromol/L). Recent studies revealed intellectual, neurologic, and neuropsychologic defi...

journal_title：Pediatric research

authors： Weglage J,Ullrich K,Pietsch M,Fünders B,Güttler F,Harms E

更新日期：1997-09-01 00:00:00

abstract：:Fetal growth and development is dependent on the transfer of amino acids from maternal to fetal blood across the microvillous plasma membrane (MVM) and basal plasma membrane of placental syncytiotrophoblast. The aim of this study was to determine the relationship of system A amino acid transporter (SysA) activity in M...

journal_title：Pediatric research

authors： Harrington B,Glazier J,D'Souza S,Sibley C

更新日期：1999-06-01 00:00:00

abstract：:Human Bifidobacterium sp strain bifidum (B. bifidum) was administered to BALB/c lactating mice (n = 58) and their litters (n = 327 pups) to evaluate the ingested strain's adherent properties and ability to inhibit murine rotavirus (MRV) infection. ELISA and anaerobic bacteriologic techniques were used to measure MRV s...

journal_title：Pediatric research

authors： Duffy LC,Zielezny MA,Riepenhoff-Talty M,Dryja D,Sayahtaheri-Altaie S,Griffiths E,Ruffin D,Barrett H,Rossman J,Ogra PL

更新日期：1994-06-01 00:00:00

abstract：BACKGROUND:Observational studies suggest that asthma control improves after adenotonsillectomy, but longitudinal studies that correlate the effect of the procedure on the levels of biomarkers associated with airway inflammation are limited. METHODS:We conducted a longitudinal, observational study on pediatric patients...

journal_title：Pediatric research

authors： Levin JC,Gagnon L,He X,Baum ED,Karas DE,Chupp GL

更新日期：2014-03-01 00:00:00

abstract：:In preterm infants, low levels of insulin like growth factor 1 (IGF-I) have been associated with impaired growth and retinopathy of prematurity. Our objective was to study safety and pharmacokinetics of i.v. administered rhIGF-I with its binding protein 3 (rhIGFBP-3) to preterm infants. At 3 d chronological age, an i....

journal_title：Pediatric research

authors： Löfqvist C,Niklasson A,Engström E,Friberg LE,Camacho-Hübner C,Ley D,Borg J,Smith LE,Hellström A

更新日期：2009-05-01 00:00:00

abstract：:Music is widely used to enhance well-being. We wished to assess music's effect on pediatric oncology outpatients. Patients who had leukemia and were in maintenance or consolidation outpatient treatment served as their own control at two visits. At visit 1, children rested for 20 min; at visit 2, for 20 min they listen...

journal_title：Pediatric research

authors： Kemper KJ,Hamilton CA,McLean TW,Lovato J

更新日期：2008-07-01 00:00:00

abstract：:Human intestinal mucosa consists of highly active epithelial cells in continual renewal and differentiation processes located at different portions of the villi. The crypt contains abundant replicating cells which, upon reaching the villus tip, acquire their fully differentiated state. Besides its well recognized role...

journal_title：Pediatric research

authors： Delvin EE,Lopez V,Levy E,Ménard D

更新日期：1996-11-01 00:00:00

abstract：:Previous studies have demonstrated metabolic dysfunction in the mononuclear cells of some children with abnormal cell-mediated immunity. Interpretation of these observations has been complicated by the extreme heterogeneity of cell types examined. The glycolytic metabolism of relatively enriched T-cells, non-T mononuc...

journal_title：Pediatric research

authors： Storch S,Klein W,Feig SA,Henderson T

更新日期：1980-02-01 00:00:00

abstract：:To assess sleep organization in premature infants of < 35 wk gestational age (w GA), we performed polygraphic recordings in 24 neurologically normal neonates (eight per group): artificially ventilated 27-30 and 31-34 w GA infants and nonventilated 31-34 w GA infants. Sleep states were defined by concordance of EEG and...

journal_title：Pediatric research

authors： Curzi-Dascalova L,Figueroa JM,Eiselt M,Christova E,Virassamy A,d'Allest AM,Guimarâes H,Gaultier C,Dehan M

更新日期：1993-11-01 00:00:00