Abstract：
:This paper reviews key issues found to affect acceptability and preferences for vaginal products to prevent HIV infection or HIV and pregnancy. We focus on the interplay between the biological and physico-chemical aspects of formulation and the social and behavioral issues that may affect use. The need for an HIV prevention product that women can use is driven by women's increased biological and social vulnerability to HIV infection, and thus social and behavioral research on microbicide acceptability has been conducted alongside, as well as separate from, the earliest product development efforts. Some acceptability and preference issues are specific to a product's dosage form, use-requirements, and/or use indications, while others pertain to any vaginal product used for prevention of HIV or pregnancy. Although most of the work cited here was published since 2010, it draws on a much longer trajectory of research.
journal_name
Adv Drug Deliv Revjournal_title
Advanced drug delivery reviewsauthors
Woodsong C,Holt JDdoi
10.1016/j.addr.2015.02.004subject
Has Abstractpub_date
2015-09-15 00:00:00pages
146-54eissn
0169-409Xissn
1872-8294pii
S0169-409X(15)00015-0journal_volume
92pub_type
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