Photochemical mechanisms of light-triggered release from nanocarriers.

Abstract:

:Over the last three decades, a handful of photochemical mechanisms have been applied to a large number of nanoscale assemblies that encapsulate a payload to afford spatio-temporal and remote control over activity of the encapsulated payload. Many of these systems are designed with an eye towards biomedical applications, as spatio-temporal and remote control of bioactivity would advance research and clinical practice. This review covers five underlying photochemical mechanisms that govern the activity of the majority of photoresponsive nanocarriers: 1. photo driven isomerization and oxidation, 2. surface plasmon absorption and photothermal effects, 3. photo driven hydrophobicity changes, 4. photo driven polymer backbone fragmentation and 5. photo driven de-crosslinking. The ways in which these mechanisms have been incorporated into nanocarriers and how they affect release are detailed, as well as the advantages and disadvantages of each system.

journal_name

Adv Drug Deliv Rev

authors

Fomina N,Sankaranarayanan J,Almutairi A

doi

10.1016/j.addr.2012.02.006

subject

Has Abstract

pub_date

2012-08-01 00:00:00

pages

1005-20

issue

11

eissn

0169-409X

issn

1872-8294

pii

S0169-409X(12)00029-4

journal_volume

64

pub_type

杂志文章,评审
  • Mechanical stimulation in the engineering of heart muscle.

    abstract::Recreating the beating heart in the laboratory continues to be a formidable bioengineering challenge. The fundamental feature of the heart is its pumping action, requiring considerable mechanical forces to compress a blood filled chamber with a defined in- and outlet. Ventricular output crucially depends on venous loa...

    journal_title:Advanced drug delivery reviews

    pub_type: 杂志文章,评审

    doi:10.1016/j.addr.2015.09.001

    authors: Liaw NY,Zimmermann WH

    更新日期:2016-01-15 00:00:00

  • Overcoming drug resistance by regulating nuclear receptors.

    abstract::Drug resistance involves multiple mechanisms. Multidrug resistance (MDR) is the leading cause of treatment failure in cancer therapy. Elevated levels of MDR proteins [members of the ATP-binding cassette (ABC) transporter family] increase cellular efflux and decrease the effectiveness of chemotherapeutic agents. As a s...

    journal_title:Advanced drug delivery reviews

    pub_type: 杂志文章,评审

    doi:10.1016/j.addr.2010.07.008

    authors: Chen T

    更新日期:2010-10-30 00:00:00

  • Thioredoxin 1 delivery as new therapeutics.

    abstract::Thioredoxin 1 (Trx 1) is a redox-active small protein ubiquitously present in human body. It is one of the defensive proteins induced in response to various stress conditions. In addition to its anti-oxidative effect by dithiol-disulfide exchange in its active site, Trx 1 has anti-apoptotic and anti-inflammatory effec...

    journal_title:Advanced drug delivery reviews

    pub_type: 杂志文章,评审

    doi:10.1016/j.addr.2009.01.003

    authors: Nakamura H,Hoshino Y,Okuyama H,Matsuo Y,Yodoi J

    更新日期:2009-04-28 00:00:00

  • Tuftsin-bearing liposomes in treatment of macrophage-based infections.

    abstract::The use of liposomes as drug carriers in treatment of various diseases has been explored extensively for more than 20 years. 'Conventional' liposomes, when administered in vivo by a variety of routes, rapidly accumulate in the mononuclear phagocyte system (MPS). The inherent tendency of the liposomes to concentrate in...

    journal_title:Advanced drug delivery reviews

    pub_type: 杂志文章,评审

    doi:10.1016/s0169-409x(99)00061-7

    authors: Agrawal AK,Gupta CM

    更新日期:2000-03-30 00:00:00

  • Targeting podocyte-associated diseases.

    abstract::Injury to the podocytes is the initiating cause of many renal diseases, leading to proteinuria with possible progression to end-stage renal disease. Podocytes are highly specialized cells, with an important role in maintaining the glomerular filtration barrier and producing growth factors for both mesangial cells and ...

    journal_title:Advanced drug delivery reviews

    pub_type: 杂志文章,评审

    doi:10.1016/j.addr.2010.08.012

    authors: Leeuwis JW,Nguyen TQ,Dendooven A,Kok RJ,Goldschmeding R

    更新日期:2010-11-30 00:00:00

  • Oral biodrug delivery using cell-penetrating peptide.

    abstract::During the past few decades, the novel biotherapeutic agents such as peptides and proteins have been contributed to the treatment of several diseases. However, their oral absorption is significantly limited due to their poor delivery through the intestinal mucosa. Therefore, the feasible approaches are needed for impr...

    journal_title:Advanced drug delivery reviews

    pub_type: 杂志文章,评审

    doi:10.1016/j.addr.2011.12.014

    authors: Khafagy el-S,Morishita M

    更新日期:2012-05-01 00:00:00

  • Rational use of agonists and antagonists of luteinizing hormone-releasing hormone (LH-RH) in the treatment of hormone-sensitive neoplasms and gynaecologic conditions.

    abstract::Analogues of luteinizing hormone-releasing hormone (LH-RH) have made possible new approaches to the treatment of some hormone-dependent cancers and diseases and conditions which result from inappropriate sex hormone levels. In the fields of both gynaecology and oncology, the development of sustained delivery depot sys...

    journal_title:Advanced drug delivery reviews

    pub_type: 杂志文章

    doi:10.1016/s0169-409x(97)00056-2

    authors: Maria Comaru-Schally A,Schally AV

    更新日期:1997-10-13 00:00:00

  • Nanomedicine: developing smarter therapeutic and diagnostic modalities.

    abstract::The early impact of nanotechnology on medicine is beginning to get realized, with novel nanoscale therapeutic and diagnostic modalities under development or in clinical practice today. In this commentary the field of "nanomedicine" is briefly reviewed form the perspective of where we were; where we are today; and wher...

    journal_title:Advanced drug delivery reviews

    pub_type: 杂志文章,评审

    doi:10.1016/j.addr.2006.09.011

    authors: Farokhzad OC,Langer R

    更新日期:2006-12-01 00:00:00

  • Acceptability and preferences for vaginal dosage forms intended for prevention of HIV or HIV and pregnancy.

    abstract::This paper reviews key issues found to affect acceptability and preferences for vaginal products to prevent HIV infection or HIV and pregnancy. We focus on the interplay between the biological and physico-chemical aspects of formulation and the social and behavioral issues that may affect use. The need for an HIV prev...

    journal_title:Advanced drug delivery reviews

    pub_type: 杂志文章,评审

    doi:10.1016/j.addr.2015.02.004

    authors: Woodsong C,Holt JD

    更新日期:2015-09-15 00:00:00

  • Collagens--structure, function, and biosynthesis.

    abstract::The extracellular matrix represents a complex alloy of variable members of diverse protein families defining structural integrity and various physiological functions. The most abundant family is the collagens with more than 20 different collagen types identified so far. Collagens are centrally involved in the formatio...

    journal_title:Advanced drug delivery reviews

    pub_type: 杂志文章,评审

    doi:10.1016/j.addr.2003.08.002

    authors: Gelse K,Pöschl E,Aigner T

    更新日期:2003-11-28 00:00:00

  • Descriptors of irregular particle morphology and powder properties.

    abstract::The description of irregular particle morphology and powder properties may offer unique insights into the performance of materials intended for use in dry powder inhalers. A number of mathematically similar approaches have been used to study these phenomena, all based on evaluating data in terms of irregular oscillati...

    journal_title:Advanced drug delivery reviews

    pub_type: 杂志文章

    doi:10.1016/s0169-409x(97)00508-5

    authors: Concessio NM,Hickey AJ

    更新日期:1997-06-09 00:00:00

  • Prediction of cytochrome P450 mediated metabolism.

    abstract::Cytochrome P450 enzymes (CYPs) form one of the most important enzyme families involved in the metabolism of xenobiotics. CYPs comprise many isoforms, which catalyze a wide variety of reactions, and potentially, a large number of different metabolites can be formed. However, it is often hard to rationalize what metabol...

    journal_title:Advanced drug delivery reviews

    pub_type: 杂志文章,评审

    doi:10.1016/j.addr.2015.04.020

    authors: Olsen L,Oostenbrink C,Jørgensen FS

    更新日期:2015-06-23 00:00:00

  • Mechanisms of transport of polymeric and lipidic nanoparticles across the intestinal barrier.

    abstract::Unraveling the mechanisms of nanoparticle transport across the intestinal barrier is essential for designing more efficient nanoparticles for oral administration. The physicochemical parameters of the nanoparticles (e.g., size, surface charge, chemical composition) dictate nanoparticle fate across the intestinal barri...

    journal_title:Advanced drug delivery reviews

    pub_type: 杂志文章,评审

    doi:10.1016/j.addr.2016.04.014

    authors: Beloqui A,des Rieux A,Préat V

    更新日期:2016-11-15 00:00:00

  • Are there predictors of Remicade treatment success or failure?

    abstract::Infliximab (Remicade) is an antitumor necrosis factor (TNF) therapy effective in both induction and maintenance of remission in Crohn's disease. Identifying predictors of response or relapse to infliximab is important given the potential toxicities and cost of this therapy. Currently available data suggest that concur...

    journal_title:Advanced drug delivery reviews

    pub_type: 杂志文章,评审

    doi:10.1016/j.addr.2004.08.006

    authors: Su C,Lichtenstein GR

    更新日期:2005-01-06 00:00:00

  • Issues and challenges in developing ruminal drug delivery systems.

    abstract::Ruminants have a specialised digestive system that contains anaerobic bacteria and protozoa capable of digesting the cellulosic materials that are so common in plant materials. In addition, their distinct digestive system can change the metabolism and mode of action of some nutrients, medicines or other bioactive mate...

    journal_title:Advanced drug delivery reviews

    pub_type: 杂志文章,评审

    doi:10.1016/j.addr.2004.02.011

    authors: Vandamme TF,Ellis KJ

    更新日期:2004-06-23 00:00:00

  • Formulation of lipid-based delivery systems for oral administration: materials, methods and strategies.

    abstract::Oral lipid-based drug delivery systems may include a broad range of oils, surfactants, and cosolvents. This diversity makes comparison of lipid-based formulations difficult. Although the relationship between formulation and drug absorption is understood at a conceptual level, performance in vivo cannot be predicted wi...

    journal_title:Advanced drug delivery reviews

    pub_type: 杂志文章,评审

    doi:10.1016/j.addr.2007.10.010

    authors: Pouton CW,Porter CJ

    更新日期:2008-03-17 00:00:00

  • Stem-cell based organ-on-a-chip models for diabetes research.

    abstract::Diabetes mellitus (DM) ranks among the severest global health concerns of the 21st century. It encompasses a group of chronic disorders characterized by a dysregulated glucose metabolism, which arises as a consequence of progressive autoimmune destruction of pancreatic beta-cells (type 1 DM), or as a result of beta-ce...

    journal_title:Advanced drug delivery reviews

    pub_type: 杂志文章,评审

    doi:10.1016/j.addr.2018.10.010

    authors: Rogal J,Zbinden A,Schenke-Layland K,Loskill P

    更新日期:2019-02-01 00:00:00

  • Modeling transdermal drug release.

    abstract::The stratum corneum forms the outermost layer of the skin and is essentially a multilamellar lipid milieu punctuated by protein-filled corneocytes that augment membrane integrity and significantly increase membrane tortuosity. The lipophilic character of the stratum corneum, coupled with its intrinsic tortuosity, ensu...

    journal_title:Advanced drug delivery reviews

    pub_type: 杂志文章,评审

    doi:10.1016/s0169-409x(01)00113-2

    authors: Kalia YN,Guy RH

    更新日期:2001-06-11 00:00:00

  • The role of gene therapy for craniofacial and dental tissue engineering.

    abstract::Basic science advances in bone tissue engineering using osteoinductive protein therapy have already been translated to the use in patients with selected orthopedic problems. The story of the development of bone morphogenetic protein (BMP) osteoinductive therapy, from the discovery of this class of molecules in 1965 to...

    journal_title:Advanced drug delivery reviews

    pub_type: 杂志文章,评审

    doi:10.1016/j.addr.2006.03.009

    authors: Nussenbaum B,Krebsbach PH

    更新日期:2006-07-07 00:00:00

  • Disruption of the circadian system by environmental factors: Effects of hypoxia, magnetic fields and general anesthetics agents.

    abstract::The biological clock of mammals is under the control of external factors, social life and the environment, and of internal genetic factors. When the biological clock of an individual is no longer in phase with its environment, either because there is no longer any harmony (desynchronization) between the two systems (s...

    journal_title:Advanced drug delivery reviews

    pub_type: 杂志文章,评审

    doi:10.1016/j.addr.2010.06.005

    authors: Touitou Y,Coste O,Dispersyn G,Pain L

    更新日期:2010-07-31 00:00:00

  • Pharmacophotonics: utilizing multi-photon microscopy to quantify drug delivery and intracellular trafficking in the kidney.

    abstract::The recent introduction of multi-photon microscopy coupled with advances in optics, computer sciences and the available fluorophores used to label molecules of interest have empowered investigators to study the dynamic events within the functioning kidney at cellular and subcellular levels. This emerging technique, wi...

    journal_title:Advanced drug delivery reviews

    pub_type: 杂志文章,评审

    doi:10.1016/j.addr.2006.07.017

    authors: Molitoris BA,Sandoval RM

    更新日期:2006-09-15 00:00:00

  • NanoVelcro rare-cell assays for detection and characterization of circulating tumor cells.

    abstract::Circulating tumor cells (CTCs) are cancer cells shredded from either a primary tumor or a metastatic site and circulate in the blood as the potential cellular origin of metastasis. By detecting and analyzing CTCs, we will be able to noninvasively monitor disease progression in individual cancer patients and obtain ins...

    journal_title:Advanced drug delivery reviews

    pub_type: 杂志文章,评审

    doi:10.1016/j.addr.2018.03.006

    authors: Jan YJ,Chen JF,Zhu Y,Lu YT,Chen SH,Chung H,Smalley M,Huang YW,Dong J,Chen LC,Yu HH,Tomlinson JS,Hou S,Agopian VG,Posadas EM,Tseng HR

    更新日期:2018-02-01 00:00:00

  • Imaging mass spectrometry: from tissue sections to cell cultures.

    abstract::Imaging mass spectrometry (IMS) has been a useful tool for investigating protein, peptide, drug and metabolite distributions in human and animal tissue samples for almost 15years. The major advantages of this method include a broad mass range, the ability to detect multiple analytes in a single experiment without the ...

    journal_title:Advanced drug delivery reviews

    pub_type: 杂志文章,评审

    doi:10.1016/j.addr.2013.03.006

    authors: Weaver EM,Hummon AB

    更新日期:2013-07-01 00:00:00

  • Inhalation therapy: technological milestones in asthma treatment.

    abstract::The humble origins of the propellant driven metered dose inhaler, as a response to a child's enquiry, initiated an industry which supplies approximately a half billion inhalers globally for the treatment of asthma. These inhalers fall into three major groups: nebulizers; propellant driven metered dose inhalers and dry...

    journal_title:Advanced drug delivery reviews

    pub_type: 杂志文章,评审

    doi:10.1016/s0169-409x(03)00077-2

    authors: Dalby R,Suman J

    更新日期:2003-07-18 00:00:00

  • Antibody-directed enzyme prodrug therapy (ADEPT): a review.

    abstract::Antibody-directed enzyme prodrug therapy (ADEPT) is a therapeutic strategy which aims to improve the selectivity of anticancer drugs. ADEPT is a two-step antibody targeting system that has benefits over a one-step chemo-, toxin- or radioimmunoconjugate. The basic principles of ADEPT are discussed alongside the require...

    journal_title:Advanced drug delivery reviews

    pub_type: 杂志文章

    doi:10.1016/s0169-409x(97)00032-x

    authors: Springer CJ,Niculescu-Duvaz I I

    更新日期:1997-07-07 00:00:00

  • Microfabrication technologies for oral drug delivery.

    abstract::Micro-/nanoscale technologies such as lithographic techniques and microfluidics offer promising avenues to revolutionalize the fields of tissue engineering, drug discovery, diagnostics and personalized medicine. Microfabrication techniques are being explored for drug delivery applications due to their ability to combi...

    journal_title:Advanced drug delivery reviews

    pub_type: 杂志文章,评审

    doi:10.1016/j.addr.2011.11.013

    authors: Sant S,Tao SL,Fisher OZ,Xu Q,Peppas NA,Khademhosseini A

    更新日期:2012-05-01 00:00:00

  • Mathematical and pharmacokinetic modelling of epidermal and dermal transport processes.

    abstract::Topical delivery to the various regions of the skin and underlying tissues, transdermal drug delivery and dermal exposure to environmental chemicals are important areas of research. Mathematical models of epidermal and dermal transport, involving penetration of a solute through various layers of the skin, metabolism i...

    journal_title:Advanced drug delivery reviews

    pub_type: 杂志文章,评审

    doi:10.1016/j.addr.2012.04.009

    authors: Anissimov YG,Jepps OG,Dancik Y,Roberts MS

    更新日期:2013-02-01 00:00:00

  • Selective activation of anticancer prodrugs by monoclonal antibody-enzyme conjugates.

    abstract::A great deal of interest has surrounded the activities of monoclonal antibodies (mAbs), and mAb-drug, toxin and radionuclide conjugates for the treatment of human cancers. In the last few years, a number of new mAb-based reagents have been clinically approved (Rituxan, Herceptin, and Panorex), and several others are n...

    journal_title:Advanced drug delivery reviews

    pub_type: 杂志文章,评审

    doi:10.1016/s0169-409x(01)00206-x

    authors: Senter PD,Springer CJ

    更新日期:2001-12-31 00:00:00

  • Lessons from innovation in drug-device combination products.

    abstract::Drug-device combination products introduced a new dynamic on medical product development, regulatory approval, and corporate interaction that provide valuable lessons for the development of new generations of combination products. This paper examines the case studies of drug-eluting stents and transdermal patches to f...

    journal_title:Advanced drug delivery reviews

    pub_type: 杂志文章,评审

    doi:10.1016/j.addr.2011.10.008

    authors: Couto DS,Perez-Breva L,Saraiva P,Cooney CL

    更新日期:2012-01-01 00:00:00

  • Inhalation of repurposed drugs to treat pulmonary hypertension.

    abstract::Pulmonary arterial hypertension (PAH) is a rare, but severe and life-threatening disease characterized by vasoconstriction and remodeling of the pulmonary arterioles, leading to progressive increase in pulmonary vascular resistance and ultimately to right-heart failure. In the last two decades, significant progress in...

    journal_title:Advanced drug delivery reviews

    pub_type: 杂志文章,评审

    doi:10.1016/j.addr.2018.06.003

    authors: Gessler T

    更新日期:2018-08-01 00:00:00