Chronic inflammation with Helicobacter pylori infection is implicated in CD44 overexpression through miR-328 suppression in the gastric mucosa.

abstract：BACKGROUND:The ideal medication for the treatment of acid-related diseases, for example, hemorrhagic ulcers and stress-related gastric bleeding, should have a rapid onset of action to promote hemostasis and alleviate symptoms. The aim of our study was to investigate the inhibitory effects on gastric acid secretion afte...

journal_title：Journal of gastroenterology

authors： Abe Y,Inamori M,Togawa J,Kikuchi T,Muramatsu K,Chiguchi G,Kawamura H,Kobayashi N,Kirikoshi H,Sakaguchi T,Takamura T,Nakajima A,Ueno N,Sekihara H

更新日期：2004-01-01 00:00:00

abstract：:We report a case of Cruveihier-Baumgarten syndrome associated with portal vein thrombosis that developed, slowly during a 2-year period after endoscopic variceal sclerotherapy. The thrombosis led to the disappearance of the venous hum and the dilated abdominal wall veins characteristic of this syndrome. A 73-year-old ...

journal_title：Journal of gastroenterology

authors： Yamakawa O,Ohta H,Watanabe H,Motoo Y,Okai T,Kadoya M,Matsui O,Sawabu N

更新日期：1996-08-01 00:00:00

abstract：BACKGROUND:At present, squamous cell carcinoma accounts for most esophageal cancers in Japan; however, there is concern that the incidence of esophageal adenocarcinoma in Japan is increasing in comparison to Western countries. Akita Prefecture, with a population of 1 million, has the highest rate of esophageal cancer-a...

journal_title：Journal of gastroenterology

authors： Koizumi S,Motoyama S,Iijima K

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:The search is on to find more effective drug regimens for patients with severe ulcerative colitis, as conventional drugs such as sulfasalazine and its congeners fail to prevent relapse in a significant number of patients. Azathioprine has also been reported to be useful as a steroid-sparing drug in patients ...

journal_title：Journal of gastroenterology

authors： Sood A,Kaushal V,Midha V,Bhatia KL,Sood N,Malhotra V

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Although it is less frequently encountered, mesenteric vein occlusion poses as important a problem as mesenteric artery occlusion. The energy metabolism of intestinal tissue during venous occlusion and reperfusion was studied. METHODS:Male Wistar rats were studied in four groups of 17 animals each. Intestin...

journal_title：Journal of gastroenterology

authors： Kimura M,Kataoka M,Kuwabara Y,Sato A,Sugiura M,Fujii Y

更新日期：2003-01-01 00:00:00

abstract：:Primary sclerosing cholangitis is very rare in Japan. The aim of the present study was to identify the characteristics of such patients in Japan. A questionnaire was sent to the members of the Japanese Society of Gastroenterology and responses for 192 cases were analyzed. There was male predominancy (61%), and two pea...

journal_title：Journal of gastroenterology

authors： Takikawa H,Manabe T

更新日期：1997-02-01 00:00:00

abstract：BACKGROUND:Because of the wide overlap between the groups, patients with reflux esophagitis (RE) cannot be distinguished from healthy subjects by basal lower esophageal sphincter (LES) pressure. The LES has radial asymmetry, with maximum pressure on the left side. It has been noted that one directional LES pressure, de...

journal_title：Journal of gastroenterology

authors： Iwakiri K,Hayashi Y,Kotoyori M,Sugiura T,Kawakami A,Sakamoto C

更新日期：2004-07-01 00:00:00

abstract：:A case of granular cell tumor occurring in the sigmoid colon is reported. The patient, a 56-year-old man, visited our hospital for further evaluation of occult blood in his stool. Endoscopic examination revealed a yellowish, hemispheric submucosal tumor (SMT) with redness, about 6 mm in diameter, in the sigmoid colon....

journal_title：Journal of gastroenterology

authors： Endo S,Hirasaki S,Doi T,Endo H,Nishina T,Moriwaki T,Nakauchi M,Masumoto T,Tanimizu M,Hyodo I

更新日期：2003-01-01 00:00:00

abstract：:We measured urokinase-type plasminogen activator (u-PA) plasma levels in patients with various chronic liver diseases, including hepatocellular carcinoma (HCC), also measuring these levels in healthy volunteers. Plasma u-PA levels in the group of patients with decompensated liver cirrhosis (mean modified Pugh score of...

journal_title：Journal of gastroenterology

authors： Sato S,Higashi T,Ouguchi S,Hino N,Tsuji T

更新日期：1994-12-01 00:00:00

abstract：BACKGROUND:We carried out this study to evaluate the association between regulatory T cells (Treg) and prognosis and progression after cryoablation in patients with hepatitis-B virus-related hepatocellular carcinoma. METHODS:Peripheral Treg frequency in 111 patients with hepatocellular carcinoma (HCC) was detected by ...

journal_title：Journal of gastroenterology

authors： Zhou L,Fu JL,Lu YY,Fu BY,Wang CP,An LJ,Wang XZ,Zeng Z,Zhou CB,Yang YP,Wang FS

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:Most studies evaluating visceral sensation measure visceromotor response (VMR) to colorectal distention (CRD). However, CRD itself induces visceral sensitization, and little is known about the detailed characteristics of this response. The present study tried to clarify this question. METHODS:VMR was determ...

journal_title：Journal of gastroenterology

authors： Nozu T,Kumei S,Miyagishi S,Takakusaki K,Okumura T

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Pegylated interferon (PEG-IFN) plus ribavirin (RBV) therapy is the current standard of care for patients with chronic hepatitis C. Determining precisely the risk of serious adverse events (SAEs) and mortality from a single study is rather difficult because of the infrequency of such events. The aim of this s...

journal_title：Journal of gastroenterology

authors： Minami T,Kishikawa T,Sato M,Tateishi R,Yoshida H,Koike K

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND:Hypersensitive esophagus (HE) is defined by endoscopy-negative heartburn with a normal acid exposure time but positive symptom association probability (SAP) and/or symptom index (SI) on impedance-pH monitoring, and proton pump inhibitor (PPI) responsiveness. Functional heartburn (FH) is distinguished by nega...

journal_title：Journal of gastroenterology

authors： Frazzoni M,de Bortoli N,Frazzoni L,Furnari M,Martinucci I,Tolone S,Farioli A,Marchi S,Fuccio L,Savarino V,Savarino E

更新日期：2017-04-01 00:00:00

abstract：BACKGROUND:The dynamic change in gastric emptying on a minute-by-minute basis (gastric velocity) is evaluated by the 13C-octanoate breath test with deconvolution analysis. However, deconvolution is impractical, because it requires dual experiments to obtain 13CO2 excretion profiles following intraduodenal and oral admi...

journal_title：Journal of gastroenterology

authors： Sanaka M,Yamamoto T,Osaki Y,Kuyama Y

更新日期：2006-07-01 00:00:00

abstract：BACKGROUND:Hepatocellular carcinoma (HCC) caused by hepatitis B virus (HBV) often recurs after surgical or medical treatment. METHODS:Eighty consecutive patients with HBV-positive cirrhosis and HCC who underwent potentially curative ablation for HCC were analyzed. Eleven patients received long-term interferon (IFN) th...

journal_title：Journal of gastroenterology

authors： Someya T,Ikeda K,Saitoh S,Kobayashi M,Hosaka T,Sezaki H,Akuta N,Suzuki F,Suzuki Y,Arase Y,Kumada H

更新日期：2006-12-01 00:00:00

abstract：BACKGROUND:Thrombocytopenia represents an obstacle for invasive procedures in chronic liver disease (CLD) patients. We aimed to estimate the appropriate dose and evaluate the efficacy and safety of lusutrombopag for the treatment of thrombocytopenia before percutaneous liver radiofrequency ablation (RFA) for primary he...

journal_title：Journal of gastroenterology

authors： Tateishi R,Seike M,Kudo M,Tamai H,Kawazoe S,Katsube T,Ochiai T,Fukuhara T,Kano T,Tanaka K,Kurokawa M,Yamamoto K,Osaki Y,Izumi N,Imawari M

更新日期：2019-02-01 00:00:00

abstract：:Endoscopic biliary drainage (EBD) for unresectable hepatocellular carcinoma (HCC) associated with obstructive jaundice remains controversial because of the short survival of these patients. To evaluate the effectiveness of this procedure, we retrospectively studied 18 patients who had unresectable HCC with obstructive...

journal_title：Journal of gastroenterology

authors： Matsueda K,Yamamoto H,Umeoka F,Ueki T,Matsumura T,Tezen T,Doi I

更新日期：2001-03-01 00:00:00

abstract：:We reviewed reports on the efficacy of clarithromycin in eradicating Helicobacter pylori. Reports on dual and 1-week triple therapy that included clarithromycin were analyzed to assess the eradication rates of H. pylori infection. Dual therapy with clarithromycin and a proton pump inhibitor achieved eradication rates ...

journal_title：Journal of gastroenterology

authors： Satoh K,Kimura K,Takimoto T,Kihira K,Taniguchi Y,Saifuku K

更新日期：1996-11-01 00:00:00

abstract：BACKGROUND:LYVE-1, a specific marker of lymphatics, is expressed in hepatic sinusoidal endothelium. A previous study revealed that LYVE-1 expression in sinusoidal endothelium was reduced in cirrhosis. However, it is still obscure how LYVE-1 expression in sinusoidal endothelium was reduced during the disease progression...

journal_title：Journal of gastroenterology

authors： Arimoto J,Ikura Y,Suekane T,Nakagawa M,Kitabayashi C,Iwasa Y,Sugioka K,Naruko T,Arakawa T,Ueda M

更新日期：2010-03-01 00:00:00

abstract：:Sixty-two colorectal adenomas 10 mm or less in diameter, resected endoscopically and fixed in formalin for 3 days or less, were evaluated with antiproliferating cell nuclear antigen/cyclin (PCNA) monoclonal antibody to investigate the cell proliferation kinetics. All lesions were tubular adenoma with low-grade atypia....

journal_title：Journal of gastroenterology

authors： Kobayashi M,Watanabe H,Ajioka Y,Honma T,Asakura H

更新日期：1994-04-01 00:00:00

abstract：BACKGROUND:A prospective, randomized study was performed to determine whether gemcitabine infusion at a low dose (250 mg/m2) is comparable or superior to the standard-dose infusion (1000 mg/m2) in terms of the survival period, clinical benefit, and frequency of adverse effects in patients with advanced pancreatic adeno...

journal_title：Journal of gastroenterology

authors： Sakamoto H,Kitano M,Suetomi Y,Takeyama Y,Ohyanagi H,Nakai T,Yasuda C,Kudo M

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:We investigated the effects of rabeprazole compared with those of omeprazole on enterochromaffin-like cells and parietal cells in rats. METHODS:Rabeprazole or omeprazole was administered for 7 days by intraperitoneal injection (100 mg/kg or 20mg/kg once a day) and the serum gastrin concentration, the antral...

journal_title：Journal of gastroenterology

authors： Tari A,Kawano M,Kodama K,Yonei Y,Okahara S,Haruma K,Sumii K,Kajiyama G

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Nocturnal administration of branched-chain amino acid (BCAA) granules improves serum albumin levels in patients with cirrhosis. However, it is unclear whether or not this administration method can improve the patients' quality of life (QOL). In this study, we aimed to investigate the efficacy of BCAA granule...

journal_title：Journal of gastroenterology

authors： Hidaka H,Nakazawa T,Kutsukake S,Yamazaki Y,Aoki I,Nakano S,Asaba N,Minamino T,Takada J,Tanaka Y,Okuwaki Y,Watanabe M,Shibuya A,Koizumi W

更新日期：2013-02-01 00:00:00

abstract：:Adenocarcinoma of the small intestine is uncommon. Due to this paucity and the lack of specificity of symptoms, patients are usually seen late in the course of their illness, when curative therapy, mainly represented by extensive surgical resection, is unlikely. The authors report a case of primary well-differentiated...

journal_title：Journal of gastroenterology

authors： Koyama S,Araki M,Yuhara K,Murata Y,Fukutomi H,Atake S,Gohongi T,Yuzawa K,Fukao K,Kikuchi M

更新日期：1995-10-01 00:00:00

abstract：BACKGROUND:The causal association between diabetes and pancreatic cancer remains unclear in Asian populations. This study examined whether gallstones, a cholecystectomy, chronic pancreatitis and the treatment of antidiabetic agents affect the risk of subsequent pancreatic cancer for patients with diabetes in a Taiwanes...

journal_title：Journal of gastroenterology

authors： Lai HC,Tsai IJ,Chen PC,Muo CH,Chou JW,Peng CY,Lai SW,Sung FC,Lyu SY,Morisky DE

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND:The efficacy, safety, and pharmacokinetics of the combination of three direct-acting antiviral (DAA) agents (adafosbuvir [also known as AL-335], odalasvir, and simeprevir) were investigated in DAA treatment-naïve Japanese patients with genotype (GT)1 or GT2 chronic hepatitis C virus (HCV) infection, with or ...

journal_title：Journal of gastroenterology

authors： Takehara T,Chayama K,Kurosaki M,Yatsuhashi H,Tanaka Y,Hiramatsu N,Sakamoto N,Asahina Y,Nozaki A,Nakano T,Hagiwara Y,Shimizu H,Yoshida H,Huang Y,Biermer M,Vijgen L,Hayashi N

更新日期：2020-06-01 00:00:00

abstract：:We report a case of synchronous gas gangrene and spontaneous bacterial peritonitis associated with liver cirrhosis. The patient was a 52-year-old man who was being followed for decompensated liver cirrhosis. He experienced sudden onset lower abdominal pain with distension and pain in the left leg. A bullous lesion, wi...

journal_title：Journal of gastroenterology

authors： Murata K,Shimizu A,Takase K,Nakano T,Tameda Y

更新日期：1997-04-01 00:00:00

abstract：BACKGROUND:Although balloon-occluded retrograde transvenous obliteration (BRTO) is often selected to treat gastric varices caused by portal hypertension, data comparing BRTO and splenectomy with gastric devascularization (Sp + Dev) are limited. METHODS:From January 2009 to February 2018, 100 patients with gastric vari...

journal_title：Journal of gastroenterology

authors： Oshita K,Ohira M,Honmyo N,Kobayashi T,Murakami E,Aikata H,Baba Y,Kawano R,Awai K,Chayama K,Ohdan H

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:Circular RNAs (circRNAs) act as vital regulators of gene expression in a variety of cancers. However, the role of circRNAs in gastric cancer (GC) remains largely unexplored. Herein, we identified that circTMEM87A sponges miR-142-5p to promote GC progression through up-regulating ULK1 expression. METHODS:The...

journal_title：Journal of gastroenterology

authors： Wang H,Sun G,Xu P,Lv J,Zhang X,Zhang L,Wang S,Cao J,Xia Y,Xuan Z,Li B,Huang X,Jiang T,Fang L,Xu Z

更新日期：2020-11-06 00:00:00

abstract：:We report a case of primary biliary cirrhosis (PBC)-autoimmune hepatitis (AIH) overlap syndrome with concurrent idiopathic thrombocytopenic purpura (ITP) and Hashimoto's disease with positivity for anticentromere antibody. The patient was a 64-year-old woman with symptoms of jaundice and general fatigue. About 30 year...

journal_title：Journal of gastroenterology

authors： Arakawa Y,Amaki S,Miyakawa H,Sakai T,Gotou I,Tanaka N,Moriyama M,Iwasaki A,Sugitani M,Arakawa Y

更新日期：2004-01-01 00:00:00