Genetic algorithm for the medium optimization of the microalga Nannochloropsis gaditana cultured to aquaculture.

Abstract:

:A genetic algorithm has been used to optimize the composition of the culture medium for growing the microalga Nannochloropsis gaditana, based on the nutrients composition of the commercial medium ALGAL. This strategy was carried out through the implementation of 270 experiments spread over nine generations, which allowed achieving an eicosapentaenoic acid (EPA) productivity of 17.8 m gL(-1) d(-1) in a continuous culture of N. gaditana, with an increase of 23% compared to the commercial medium. The EPA yield on nitrogen and phosphorous, 0.042 and 1.146 g(EPA) g(s)(-1), respectively, were 40% and 5-fold higher, respectively, than the values obtained with the nitrogen-optimized ALGAL medium. This improvement was obtained with the medium G-8, which also allowed reducing the requirement of several nutrients such as P, Mo, Mn in 74%, 69% and 66%, respectively, as well as the thiamine content a 46%.

journal_name

Bioresour Technol

journal_title

Bioresource technology

authors

Camacho-Rodríguez J,Cerón-García MC,Fernández-Sevilla JM,Molina-Grima E

doi

10.1016/j.biortech.2014.11.057

subject

Has Abstract

pub_date

2015-02-01 00:00:00

pages

102-9

eissn

0960-8524

issn

1873-2976

pii

S0960-8524(14)01659-9

journal_volume

177

pub_type

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