Abstract:
:The heterocycles are the versatile compounds existing in almost all natural products and synthetic organic compounds, usually associated with one or the other biological activity. Among the heterocycles the thiazoles and benzothiazoles occupy a prominent position. They possess a broad range of biological activities and are found in many potent biologically active molecules and drugs such as vitamin thiamine, sulfathiazol (antimicrobial drug), ritonavir (antiretroviral drug), abafungin (antifungal drug) and tiazofurin (antineoplastic drug). The thiazole moiety is abundantly found in natural products while benzothiazole moiety is rare. In this review we disclose the literature reports of thiazoles and benzothiazoles possessing different biological activities.
journal_name
Eur J Med Chemjournal_title
European journal of medicinal chemistryauthors
Rouf A,Tanyeli Cdoi
10.1016/j.ejmech.2014.10.058subject
Has Abstractpub_date
2015-06-05 00:00:00pages
911-27eissn
0223-5234issn
1768-3254pii
S0223-5234(14)00986-6journal_volume
97pub_type
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