Bioactive thiazole and benzothiazole derivatives.

Abstract:

:The heterocycles are the versatile compounds existing in almost all natural products and synthetic organic compounds, usually associated with one or the other biological activity. Among the heterocycles the thiazoles and benzothiazoles occupy a prominent position. They possess a broad range of biological activities and are found in many potent biologically active molecules and drugs such as vitamin thiamine, sulfathiazol (antimicrobial drug), ritonavir (antiretroviral drug), abafungin (antifungal drug) and tiazofurin (antineoplastic drug). The thiazole moiety is abundantly found in natural products while benzothiazole moiety is rare. In this review we disclose the literature reports of thiazoles and benzothiazoles possessing different biological activities.

journal_name

Eur J Med Chem

authors

Rouf A,Tanyeli C

doi

10.1016/j.ejmech.2014.10.058

subject

Has Abstract

pub_date

2015-06-05 00:00:00

pages

911-27

eissn

0223-5234

issn

1768-3254

pii

S0223-5234(14)00986-6

journal_volume

97

pub_type

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