[Prognosis and treatment of patients with systemic lupus erythematosus in different age groups].

Abstract:

:The paper is concerned with observation over 470 patients with systemic lupus erythematosus (SLE) admitted to the Institute of Rheumatology, Academy of Medical Sciences of the USSR, since December 1958 to December 1983. Women (453) with a disease onset at 10 to 55 years (355 had associated SLE and nephritis, 155 presented with SLE without nephritis) accounted for the absolute majority of cases. Comparison of the disease clinical picture in 2 groups of patients, who had fallen ill at 14 to 24 years (278 subjects) and at 40 to 55 years (25 subjects) revealed a graver clinical picture in the group of patients, who had fallen ill at a younger and (nephritis in 82% against 56% in the group of older patients) and a considerably less survival as compared to the group of older patients despite more intensive care including pulse-therapy with methyl prednisolone.

journal_name

Ter Arkh

journal_title

Terapevticheskii arkhiv

authors

Ivanova MM

subject

Has Abstract

pub_date

1985-01-01 00:00:00

pages

125-8

issue

6

eissn

0040-3660

issn

2309-5342

journal_volume

57

pub_type

杂志文章
  • [Protein metabolism in patients with duodenal ulcers and mathematical modeling of its disorders].

    abstract::The amino acid composition of blood serum was studied in patients with duodenal ulcers, with this parameter characterizing protein metabolism most delicately. Essential changes were established in the amino acid composition as dependent on a number of factors: disease standing, complications and their duration, acid-f...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Khachiev GL,Ovchinnikova IV,Tursunbaev A

    更新日期:1985-01-01 00:00:00

  • [Gluten-sensitive celiac disease associated with recurrent aphthous stomatitis and schizophrenia].

    abstract::The paper describes a clinical case of celiac disease with grade 3 malabsorption, which is associated with recurrent aphthous stomatitis and schizophrenia. On readmission after 8 months of strict adherence to his gluten-free diet, the patient was observed to be in clinical remission and to have normalized laboratory i...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Sabel'nikova EA,Krums LM,Parfenov AI,Ruchkina IN,Gudkova RB,Vorob'eva NN,Levchenko SV

    更新日期:2013-01-01 00:00:00

  • [4-component chemotherapy and radiation therapy of breast cancer].

    abstract::The treatment schedule for disseminated breast carcinoma has been developed. It includes the use of adriamycin (30 mg/m2, days 1, 8, 15), methotrexate (30 mg/m2, day 1), 5-FU (600 mg/m2, day 8), and cyclophosphamide (400 mg/m2, day 15 i. v. by jet injection). A complete response was obtained in 50 to 56% of the patien...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Gritsaĭ AA,Lichinitser MR,Vyshinskaia GV,Kondrat'eva AP,Aplevich NN

    更新日期:1986-01-01 00:00:00

  • [Hematosalivary mechanisms of regulation in rheumatoid arthritis].

    abstract:AIM:To study biochemical indicators of the hematosalivary barrier operation in varying activity of articular inflammation and their correlations. MATERIAL AND METHODS:Biochemical indices of mixed saliva and peripheral blood were studied in 38 healthy subjects and 99 patients with rheumatoid arthritis (RA). RESULTS:Op...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Ulanova EA,Grigor'ev IV,Novikova IA

    更新日期:2001-01-01 00:00:00

  • [Comparative evaluation of various methods of immunosuppressive therapy in severe bronchial asthma].

    abstract::Altogether 216 patients with grave infection-dependent (49.5%) and autoimmune (50.5%) bronchial asthma received 311 courses of immunosuppressant therapy, with follow up periods up to 8 years. According to the clinico-immunologic data the patients were distributed into 4 groups. The basic drugs were (1) azathioprin, (2...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Rudyk BI

    更新日期:1985-01-01 00:00:00

  • [Effect of corticosteroid therapy on the survival of patients with idiopathic dermatomyositis].

    abstract::The 5- and 10-year survival rates of all 114 patients with primary DM were 89 and 81%, respectively. Significantly lower survival rates were noted in the patients receiving late and inadequate therapy. Corticosteroid therapy radically changed the outcome of DM, mainly due to early diagnosis and adequate therapy. A sta...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Zhanuzakov MA,Vinogradova OM,Solov'eva AP

    更新日期:1986-01-01 00:00:00

  • [Study of the comparative anti-arrhythmic effectiveness of allapinin, ethacizine and mexitil in patients with ventricular disorders of cardiac rhythm].

    abstract::A double blind randomized cross-over study was conducted to analyze antiarrhythmic activity of the new Soviet drugs allapinin , ethacizine in comparison with mexitil. Altogether 33 patients with ventricular disorders of cardiac rhythm of high gradations after Lown B. were investigated including patients with paroxysma...

    journal_title:Terapevticheskii arkhiv

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Smetnev AS,Golitsyn SP,Levin ER,Sokolov SF,Koltunova MI

    更新日期:1988-01-01 00:00:00

  • [Rare forms of paraproteinemic hemoblastosis].

    abstract::The paper is concerned with 10 cases of multiple myeloma with myeloid (myeloma-myeloid) splenomegaly and myelemia; 4 cases of chronic subleukemic (or aleukemic) lymphocyte plasma cell leukemia with paraproteinemia G which do not differ in the clinical or morphological picture from Waldenström's macroglobulinemia ("Wal...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Andreeva NE

    更新日期:1984-01-01 00:00:00

  • [The possibilities of an individual approach to intra-articular drug administration in rheumatoid arthritis patients].

    abstract::A study was made of the possibilities of an individual approach to intraarticular administration of protease inhibitors, cytostatics and orgoteine in patients with rheumatoid arthritis (RA). The activity of hyaluronidase, superoxide dismutase, the level of rheumatoid factor and the phagocyte count in synovial fluid we...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Matveĭkov GP,Soroka NF,Maksimovich AB

    更新日期:1989-01-01 00:00:00

  • [Characteristics of blood pressure in schoolchildren 7-17 years old (based on one-stage and prospective studies)].

    abstract::One-stage epidemiological survey permitted one to define the limits of normal blood pressure values in schoolchildren aged 7-17 years for each age-sexual group differentially. Isolated blood pressure elevation was found to be rare, amounting to 4.4% in boys and to 3.1% in girls. The rate of new cases of elevated blood...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Tubol IB,Il'chenko IN,Akhmeteli MA,Zhukovskiĭ GS,Burlutskiĭ GI

    更新日期:1984-01-01 00:00:00

  • Clinical observation of a combination of diffuse alveolar-septal pulmonary lesion and amyloid cardiomyopathy in systemic AL-amyloidosis in the elderly.

    abstract::A rare observation of systemic AL-amyloidosis with a debut in old age, accompanied by diffuse alveolar-septal lesion of the lungs and mediastinal lymphadenopathy in combination with amyloid cardiomyopathy in the absence of pathology of kidney and liver function. ...

    journal_title:Terapevticheskii arkhiv

    pub_type:

    doi:10.26442/00403660.2018.12.000016

    authors: Tret'yakov AY,Zakharchenko SP,Tret'yakova VA,Ermilov OV,Shekhovtsov SA,Khabibulin RR,Aleinikova KS,Dan VS,Leshcheva NA

    更新日期:2018-12-30 00:00:00

  • [Effects of endotheline and nitric oxide on vascular tonicity in patients with chronic cardiac failure].

    abstract:AIM:To examine effects of endotheline-1 (ET-1) and nitric oxide (NO) on endothelium-dependent mechanisms of vascular tonicity regulation in patients with chronic cardiac failure (CCF) of FC I-IV (NYHA). MATERIAL AND METHODS:Vascular reactions of 94 patients with CCF of FC I-IV were examined according to D.S. Celermaje...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Denisov EN,Kots IaI,Bakhtiiarov RZ,Gumanova NG

    更新日期:2007-01-01 00:00:00

  • [Humoral regulators of erythropoiesis during the body's adaptation to chronic respiratory insufficiency].

    abstract::It was revealed during examination of 91 patients with chronic nonspecific lung diseases for the blood titers of erythropoietin, erythrocytic chalones, erythrocyte hemolysis products and medium molecules that in the stage I respiratory failure, there were no material changes in the titres of erythrocyte hemolysis prod...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Aleksandrov OV,Gudim VI,Stulova OIu,Leont'ev AV,Neustroev GV

    更新日期:1989-01-01 00:00:00

  • [A cytokine status in chronic alcoholic and biliary pancreatitis].

    abstract:AIM:To determine characteristics of a cytokine status in chronic pancreatitis (CP) depending on etiological factor, stage of the disease, complications, therapy. Material and methods. 72 patients had chronic alcoholic pancreatitis (CAP), 38 patients--chronic biliary pancreatitis (CBP). Control group consisted of 20 hea...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Vinokurova LV,Zhivaeva NS,Tsaregorodtseva TM,Serova TI

    更新日期:2006-01-01 00:00:00

  • [Levels of biologically active substances in the blood of patients resistant and nonresistant to antihypertensive therapy].

    abstract:AIM:To clarify the role of differences in the levels of some biologically active substances (BAS) in plasma of patients with resistance to therapy or without it measured before treatment, during treatment and application of plasmapheresis. MATERIALS AND METHODS:Resistance to therapy was assessed clinically and accordi...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Tabak'ian EA,Dmitriev VV,Masenko VP,Kukharchuk VV

    更新日期:1999-01-01 00:00:00

  • [Primary mediastinal (thymic) large B-cell lymphoma: review of the literature and author's own data].

    abstract:AIM:To study morphoimmunological and clinical features of primary mediastinal large B-cell lymphoma (PMLBCL). MATERIAL AND METHODS:We analysed the results of biopsy material study and treatment of 86 PMLBCL patients, effects of different factors on the disease prognosis, efficacy of some therapeutic programs and overa...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章,评审

    doi:

    authors: Kichigina MIu,Tumian GS,Kovrigina AM,Trofimova OP,Larionova VB,Chekan AA,Bykov DA,Osmanov DSh

    更新日期:2011-01-01 00:00:00

  • [Correlations between the levels of vitamin D, parathormone, calcium, blood phosphates in patients with chronic kidney disease not treated with kidney replacement therapy].

    abstract:AIM:To characterize correlations between the levels of vitamin D, parathormone, calcium, blood phosphates in patients with different stages of chronic disease of the kidney (CDK) given no therapy replacing renal function (TRRF). MATERIAL AND METHODS:Serum levels of creatinine, electrolytes, parathormone (PTH), 25(OH)-...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Smirnov AV,Volkov MM,Galkina OV,Zhloba AA,Emanuél' VL

    更新日期:2009-01-01 00:00:00

  • [The effect of micronized phenofibrate on the lipoproteins of the blood plasma at different initial lipid levels].

    abstract::Novel antihyperlipidemic micronized phenofibrate lipantil 200 M was tested for safety and efficacy (one 200 mg capsule a day for 3 months) in 27 patients having cholesterol level above 6.5 mmol/l. The effect emerged upon 1 month of administration and persisted till the end of the treatment. In combined hyperlipidemia ...

    journal_title:Terapevticheskii arkhiv

    pub_type: 临床试验,杂志文章

    doi:

    authors: Perova NV,Ozerova IN,Kalinina AM,Pavlova LI,Olfer'ev AM,Mel'kina OE,Golubev MA,Oganov RG

    更新日期:1996-01-01 00:00:00

  • [Sjögren's syndrome in children].

    abstract::The authors summed up the results of a many-year study of 13 children with Sjogren's diseases and syndrome, presented clinical characterization of patients, a course of this childhood pathology, some therapeutic problems and catamnestic data. An excerpt from a case history of a child with Sjogren's syndrome was given....

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Kuz'mina NN,Melikhova NI,Shaĭkov AV,Gordeev GI

    更新日期:1988-01-01 00:00:00

  • [Non-Hodgkin's lymphomas of the spleen and their pathomorphosis following splenectomy].

    abstract::Clinico-morphological correlations in non-Hodgkin's splenic lymphomas (NHL) have shown that a clinical course and hematological symptoms of splenic NHL correlate with a morphological variant of disease. Blast forms have a more aggressive course. Data on the clinical pathomorphosis of splenic NHL after splenectomy sugg...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Korchmaru IF,Iakovleva IA

    更新日期:1987-01-01 00:00:00

  • [Biliary tract in patients with chronic viral hepatitides].

    abstract:AIM:To characterize motor-kinetic and inflammatory changes in extrahepatic biliary tracts and gallbladder in patients with chronic viral hepatitis (CVH). To ascertain whether there is a pathogenetic correlation between affection of the biliary system and viral infection. MATERIAL AND METHODS:The condition of the bilia...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Pal'tsev AI,Osipenko MF,Voloshina NB

    更新日期:2005-01-01 00:00:00

  • [The frequency and clinical aspects of extraesophageal syndromes in elderly patients with gastroesophageal reflux disease].

    abstract:AIM:To investigate the frequency of extraesophageal syndromes in elderly patients with gastroesophageal reflux disease (GERD). MATERIALS AND METHODS:This cross-sectional study was conducted to compare the clinical manifestations of GERD in 1100 patients aged 60 to 75 years and in 453 patients aged 36 to 60 years. A co...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:10.17116/terarkh201688228-32

    authors: Tsukanov VV,Kasparov EV,Onuchina EV,Vasyutin AV,Butorin NN,Amelchugova OS,Tonkikh YL

    更新日期:2016-01-01 00:00:00

  • [Errors in the diagnosis of tuberculosis of the respiratory organs in a pulmonological hospital and the possibilities of their prevention].

    abstract::Respiratory tuberculosis in a pulmonary inpatient setting is not rare but, as a rule, is not diagnosed in time. Tuberculosis-directed alertness, especially in patients with an atypical lingering course of disease, the absence of the effect of nonspecific antibacterial therapy, risk factors (immunodeficiency state, dia...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Daniliak IG,Rostislavina OA,Solomakhina NI

    更新日期:1988-01-01 00:00:00

  • [Nitric-oxidergic mechanisms in the regulation of the bronchi and their significance in the pathogenesis of bronchial asthma].

    abstract:AIM:Assessment of NO-synthase (NOS) activity in bronchial asthma (BA) basing on cytochemical identification and quantitation of NADPN-diaphorase. MATERIALS AND METHODS:Operative samples from 12 BA patients and biopsies from 8 patients free of bronchial inflammation or obstruction. Experimental data on control and BA r...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Nevzorova VA,Eliseeva EV,Zuga MV,Protopopova MIu,Gel'tser BI

    更新日期:1998-01-01 00:00:00

  • [New opportunities for inhaled therapy for inflammatory diseases of the respiratory system].

    abstract::The paper considers current approaches to mucoregulatory therapy for various inflammatory diseases of the respiratory system. It gives the advantages and disadvantages of common drugs used in their treatment. Emphasis is laid on the use of inhaled hypertonic saline of NaCl in combination with hyaluronic acid (Hyaneb)....

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章,评审

    doi:10.17116/terarkh2017898110-112

    authors: Ignatova GL,Antonov VN

    更新日期:2017-01-01 00:00:00

  • [Use of nonsteroidal anti-inflammatory drugs in case of ankylosing spondylitis: long and persistently!].

    abstract::Nonsteroidal anti-inflammatory drugs (NSAIDs) are extensively used in the treatment of rheumatic diseases to relieve pain and signs of inflammation. However, when treated for ankylosing spondylosis (AS), NSAIDS exert both symptomatic and structure-modifying effects, by slowing down the development of vertebral ankylos...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章,评审

    doi:

    authors: Karateev AE,Erdes ShF

    更新日期:2014-01-01 00:00:00

  • [Burning mouth syndrome (glossalgia)].

    abstract::Burning mouth syndrome (glossalgia) is manifested by oral pin and tingling sensations, numbness and even burning and severe pains, more frequently in the tongue. Unpleasant sensations may involve the anterior two thirds of the tongue or be extended to the front part of the hard palate and the mucous membrane of the lo...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章,评审

    doi:

    authors:

    更新日期:2014-01-01 00:00:00

  • [Brachial artery responsiveness in patients with systemic lupus erythematosus and scleroderma systematica].

    abstract:AIM:to evaluate brachial artery (BA) endothelial vasomotor function in patients with systemic lupus erythematosus (SLE) and scleroderma systematica (SDS), by using noninvasive studies. Subjects and methods. Sixty-five patients, including 25 with SLE, 20 with SDS, and 20 with atherosclerosis (AS) obliterans of lower ext...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Vinogradov AA,Shilkina NP,Kostyreva NA

    更新日期:2010-01-01 00:00:00

  • [Quality of life and cognitive functions in patients with end-stage renal failure on hemodialysis using a succinate-containing dialyzing solution].

    abstract:AIM:To assess changes in quality of life (QL) and cognitive functions in patients with end-stage renal failure (ESRF) treated with hemodialysis using a succinate-containing dialyzing solution (SCDS). SUBJECTS AND METHODS:Sixty-seven patients with ESRF on hemodialysis using SCDS were examined. The investigators determi...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Smirnov AV,Vasil'eva IA,Nesterova OB,Golubev RV,Vasil'ev AN,Korosteleva NIu,Starosel'skiĭ KG

    更新日期:2014-01-01 00:00:00

  • [Magnetic resonance relaxometry of serum in patients with different forms of cellulitis in the dynamics of the disease].

    abstract:AIM:To study the time of nuclear magnetic resonance (NMR) of spin-lattice serum relaxation (T1) in the dynamics of an infectious process in patients with different forms of erysipelas. MATERIALS AND METHODS:37 patients with different clinical forms of erysipelas were examined in the acute period of the disease and in ...

    journal_title:Terapevticheskii arkhiv

    pub_type: 杂志文章

    doi:

    authors: Erovichenkov AA,Kozinets GI,Popova OV,Anokhina GI,Kolaeva NV,Shabalina OIu,Pak SG

    更新日期:2003-01-01 00:00:00