Signet-ring cell carcinoma coexisting with adenocarcinoma arising in a choledochal cyst: report of a case.

Abstract:

:Signet-ring cell carcinoma (SRCC) is rare in the biliary system. We report a case of SRCC coexisting with adenocarcinoma, arising in a choledochal cyst of the extrahepatic bile duct. The patient was a 52-year-old man, hospitalized for the investigation of jaundice and pruritus. Abdominal computed tomography and magnetic resonance cholangiopancreatography showed a huge choledochal cyst and distal common bile duct cancer. The patient underwent a pancreaticoduodenectomy with extended lymph node dissection. Histologic examination confirmed an SRCC coexisting with adenocarcinoma arising in a choledochal cyst. Postoperative chemotherapy had to be discontinued after only two cycles because the patient suffered serious side effects. Recurrence was detected in the bilioenteric anastomosis 4 months after surgery, and he died 6 months after surgery. To our knowledge, this represents the first case of SRCC arising in a choledochal cyst of the extrahepatic bile duct ever to be reported.

journal_name

Surg Today

journal_title

Surgery today

authors

Hua R,Zhang JF,Liu W,Huo YM,Sun YW

doi

10.1007/s00595-014-1049-3

subject

Has Abstract

pub_date

2015-08-01 00:00:00

pages

1049-52

issue

8

eissn

0941-1291

issn

1436-2813

journal_volume

45

pub_type

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