Significance of lymph node metastasis in pancreatic neuroendocrine tumor.

Abstract:

PURPOSE:Pancreatic neuroendocrine tumor (PNET) is relatively rare and has a generally better prognosis than does pancreatic cancer. However, as its prognosis in patients with lymph node metastasis (LNM) is unclear, lymph node dissection for PNET is controversial. Our study aimed to clarify the significance of LNM in PNET. METHODS:We retrospectively examined 83 PNET patients who underwent pancreatic resections with lymph node dissection at Kumamoto University Hospital, Saiseikai Kumamoto Hospital, and Kumamoto Regional Medical Center from April 2001 to December 2014. Their clinicopathological parameters were analyzed by the absence or presence of LNM, and with regard to the disease-free survival (DFS) and overall survival (OS). A predictive score of LNM was also made using the age, tumor size, primary tumor location, and tumor function. RESULTS:Although the 5-year OS was 74.8% for LNM+ and 94.6% for LNM- (P = 0.002), LNM was not an independent risk factor for the OS in a multivariate analysis. However, tumors larger than 1.8 cm were found to be an independent prognostic factor, and the cut-off value for the predictive score was 1.69. CONCLUSIONS:Although LNM was not an independent prognostic factor, lymph node dissection is recommended for patients whose predictive score is larger than 1.69.

journal_name

Surg Today

journal_title

Surgery today

authors

Taki K,Hashimoto D,Nakagawa S,Ozaki N,Tomiyasu S,Ohmuraya M,Arima K,Kaida T,Higashi T,Sakamoto K,Sakata K,Okabe H,Nitta H,Hayashi H,Chikamoto A,Beppu T,Takamori H,Hirota M,Baba H

doi

10.1007/s00595-017-1485-y

subject

Has Abstract

pub_date

2017-09-01 00:00:00

pages

1104-1110

issue

9

eissn

0941-1291

issn

1436-2813

pii

10.1007/s00595-017-1485-y

journal_volume

47

pub_type

杂志文章
  • Videothoracoscopic surgery for thoracic neurogenic tumors: a 7-year experience.

    abstract::While videothoracoscopic surgery has rapidly become accepted as an effective method of performing minimally invasive surgery, the advantages and feasibility of using this surgical technique for the treatment of neurogenic tumors of the thorax are not yet well defined. Between August 1992 and May 1999, 15 solitary thor...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s005950070016

    authors: Sakumoto N,Inafuku S,Shimoji H,Nomura K,Honma K,Kawabata T,Ohta M,Kuniyoshi M,Ishikawa K,Genka K

    更新日期:2000-01-01 00:00:00

  • Ultrasonographic measurement of intima-media thickness of the carotid artery before coronary artery bypass grafting.

    abstract:PURPOSE:We evaluated the usefulness of measuring intima-media thickness (IMT) of the carotid artery by ultrasonography before coronary artery bypass grafting (CABG). METHODS:Seventy-three patients who underwent carotid ultrasonography before CABG were selected for this study. The maximum IMT (max IMT) in the bilateral...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-004-2880-8

    authors: Nishimura Y,Okamura Y,Fujiwara K,Sekii H,Yamamoto S,Hatada A,Hisaoka T

    更新日期:2005-01-01 00:00:00

  • Effectiveness of scheduled intravenous acetaminophen in the postoperative pain management of video-assisted thoracic surgery.

    abstract:PURPOSE:The scheduled administration of intravenous acetaminophen (scheduled-IV-AcA) is one of the more effective multimodal analgesic approaches for postoperative pain in abdominal/orthopedic surgeries. However, there is little evidence concerning scheduled-IV-AcA after general thoracic surgery, especially when limite...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-020-02127-y

    authors: Shikatani Y,Soh J,Shien K,Kurosaki T,Ohtani S,Yamamoto H,Taniguchi A,Okazaki M,Sugimoto S,Yamane M,Oto T,Morimatsu H,Toyooka S

    更新日期:2020-09-02 00:00:00

  • The succinate dehydrogenase inhibition test for evaluating biopsy specimens and resected tumors of advanced gastric cancer.

    abstract::An in vitro chemosensitivity study of both biopsy specimens and surgically resected tumors of advanced gastric cancer from 12 patients was evaluated using the succinate dehydrogenase inhibition (SDI) test. A decrease in succinate dehydrogenase (SD) activity as an indicator of chemosensitivity was determined using cisp...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/BF00308895

    authors: Kimura H,Yonemura Y,Ohyama S,Tsugawa K,Kinoshita K,Ninomiya I,Kosaka T,Miwa K,Miyazaki I,Tanaka M

    更新日期:1992-01-01 00:00:00

  • Combination of preoperative lymphangiography using lipiodol and intraoperative lymphangiography using Evans Blue facilitates the accurate identification of postoperative chylous fistulas.

    abstract::In a 61-year-old woman who underwent extensive retroperitoneal lymph node dissection for rectal cancer, postoperative chylous ascites developed. The site of the lymphatic leak was evident on the lymphangiogram with lipiodol taken prior to the surgical repair of the leak, and another site seen on the intraoperative lym...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/BF00311375

    authors: Kohnoe S,Takahashi I,Kawanaka H,Mori M,Okadome K,Sugimachi K

    更新日期:1993-01-01 00:00:00

  • Usefulness of staging laparoscopy for advanced gastric cancer.

    abstract:PURPOSE:The aim of this study was to clarify the usefulness of staging laparoscopy for planning the treatment strategy in patients with advanced gastric cancer. METHODS:This was a retrospective study of patients with gastric cancer who underwent staging laparoscopy. The patients were divided into three groups accordin...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-009-4017-6

    authors: Shimizu H,Imamura H,Ohta K,Miyazaki Y,Kishimoto T,Fukunaga M,Ohzato H,Tatsuta M,Furukawa H

    更新日期:2010-01-01 00:00:00

  • Receiver-operating characteristic analysis of leukocyte counts and serum C-reactive protein levels in children with advanced appendicitis.

    abstract:PURPOSE:To assess the diagnostic value of the white blood cell count (WBC) and serum C-reactive protein (CRP) level in children with advanced appendicitis. METHODS:We reviewed 289 children ranging in age from 3 to 15 years old, who underwent appendectomy in our hospital between 1993 and 2003. The advanced appendicitis...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-006-3189-6

    authors: Okamoto T,Sano K,Ogasahara K

    更新日期:2006-01-01 00:00:00

  • Immunologically induced coronary artery stenosis in allografts after heart and heart-lung transplantation in rats.

    abstract::The role of the lung in suppressing immunologically induced coronary artery stenosis after heterotopic allograft transplantation was studied in rats. Thirty-nine recipients were divided into two groups: untreated and treated. The untreated group was divided into two subgroups--the heart allograft TH group and the hear...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/BF00308821

    authors: Ueki K,Hamano K,Esato K

    更新日期:1992-01-01 00:00:00

  • Laparoscopic hemi-splenectomy.

    abstract::Laparoscopic splenectomy is now established as a safe and feasible procedure. However, it remains associated with some short- and long-term postoperative complications, especially infectious complications. To our knowledge, this is the first report (with video) focusing on the safety and feasibility of laparoscopic he...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-018-1639-6

    authors: De Pastena M,Nijkamp MW,van Gulik TG,Busch OR,Hermanides HS,Besselink MG

    更新日期:2018-07-01 00:00:00

  • Surgical treatment of a cardiac papillary fibroelastoma developing from the chordae of the tricuspid valve: report of a case.

    abstract::Papillary fibroelastoma is a rare, benign cardiac tumor that can cause multiple emboli. We report herein a case of papillary fibroelastoma developing from the chordae of the tricuspid valve which was detected by echocardiography and confirmed by surgical resection. To our knowledge, this is only the fifth documented c...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s005950050154

    authors: Nishimura Y,Naito Y,Fujiwara K,Komai H,Noguchi Y

    更新日期:1998-01-01 00:00:00

  • The marked anticancer effect of combined VCR, MTX, and indomethacin against drug-resistant recurrent small cell lung carcinoma after conventional chemotherapy: report of a case.

    abstract::In a previous study, we discovered that indomethacin was an effective modulator of the sensitivity of pulmonary carcinoma cells to vincristine (VCR), methotrexate (MTX), adriamycin (ADR), and etoposide (VP-16). We describe herein the case of a 61-year-old-man with multiple brain, lung, liver, and bone metastases from ...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/BF02482998

    authors: Kobayashi S,Okada S,Hasumi T,Sato N,Fujimura S

    更新日期:1999-01-01 00:00:00

  • Oncoplastic surgery for Japanese patients with breast cancer of the lower pole.

    abstract::This report presents the results of oncoplastic surgery in three Japanese patients with breast cancer lesions involving the lower pole of the breast. Their breasts were ptotic, and their lesions were considered to be suitable for breast conservation surgery. There were treated with partial mastectomy resection using v...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-011-4490-6

    authors: Kijima Y,Yoshinaka H,Hirata M,Mizoguchi T,Ishigami S,Nakajo A,Arima H,Ueno S,Natsugoe S

    更新日期:2011-10-01 00:00:00

  • Risk factors and measures of pulmonary complications after thoracoscopic esophagectomy for esophageal cancer.

    abstract:PURPOSE:Postoperative pulmonary complications (PCs) after thoracoscopic esophagectomy for esophageal cancer (EC) still occur too frequently. We conducted this study to identify the risk factors for PCs developing in EC patients who undergo thoracoscopic esophagectomy. METHODS:The subjects of this retrospective study w...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-018-1721-0

    authors: Ohi M,Toiyama Y,Omura Y,Ichikawa T,Yasuda H,Okugawa Y,Fujikawa H,Okita Y,Yoshiyama S,Hiro J,Araki T,Kusunoki M

    更新日期:2019-02-01 00:00:00

  • A subacute hypoxic model using a pig.

    abstract:PURPOSE:A large animal model of hypoxia is necessary to develop a new therapeutic method for respiratory failure. METHODS:The experiments were performed on six pigs weighing from 15 to 19 kg. Under general anesthesia the left chest was opened and the left main bronchus was closed by a stapler. A Swan-Ganz catheter was...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-005-3067-7

    authors: Kotani K,Nagahiro I,Nakanishi H,Mori H,Osaragi T,Ando A,Shimizu N

    更新日期:2005-01-01 00:00:00

  • Distant peritoneal metastasis to a mesh-plug prosthesis in a gastrointestinal cancer patient: report of a case.

    abstract::A case of distant metastasis to mesh-plug prosthesis in gastrointestinal cancer is presented herein. An 88-year-old man had received mesh-plug repair with high ligation for a recurrence of a right inguinal hernia. Six months later, advanced gastric cancer and advanced transverse colon cancer were detected, and therefo...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-003-2597-0

    authors: Imai M,Kondo Y,Masuko H,Okada K,Osawa S,Ishizu H,Nishida Y,Hata T,Uemura K,Kina M,Honda S,Ishiyama G,Takahashi T,Hino A

    更新日期:2003-01-01 00:00:00

  • Successful preoperative preparation for thyroidectomy in Graves' disease using lithium alone: report of two cases.

    abstract::To elucidate the effect of lithium carbonate in the preoperative preparation of patients with Graves' disease, it was given without any other antithyroid medication to two patients as an alternative to thionamide, which had caused adverse effects. The initial dose of lithium carbonate was 600 mg/day, and the final dos...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/BF01427042

    authors: Mochinaga N,Eto T,Maekawa Y,Tsunoda T,Kanematsu T,Izumi M

    更新日期:1994-01-01 00:00:00

  • Single-incision laparoscopic cholecystectomy for cholecystitis requiring percutaneous transhepatic gallbladder drainage.

    abstract:PURPOSE:Single-incision laparoscopic cholecystectomy (SILC) has been performed for patients with gallbladder stones but without acute cholecystitis. We report our experience of performing SILC for patients with cholecystitis requiring percutaneous transhepatic gallbladder drainage (PTGBD). METHODS:We performed SILC vi...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-014-1003-4

    authors: Igami T,Aoba T,Ebata T,Yokoyama Y,Sugawara G,Nagino M

    更新日期:2015-03-01 00:00:00

  • Progress in the diagnosis and treatment of COVID-19 and the role of surgeons in the front line of the pandemic.

    abstract::The current struggle to control and contain COVID-19 is critical and surgeons are on the front line in the fight against this virus. Surgeons, and other medical workers in the field of surgery, have a solid foundation and experience in medical treatment and intensive care, and an understanding of the support of respir...

    journal_title:Surgery today

    pub_type: 杂志文章,评审

    doi:10.1007/s00595-020-02090-8

    authors: Shi YJ,Wang H

    更新日期:2020-11-01 00:00:00

  • Simultaneous occurrence of papillary intrafollicular and microcarcinomas with bilateral medullary microcarcinoma of the thyroid in a patient with multiple endocrine neoplasia type 2A: report of a case.

    abstract::We report the case of a simultaneous occurrence of papillary intrafollicular and microcarcinomas with bilateral medullary microcarcinoma of the thyroid in a patient with multiple endocrine neoplasia type 2A. The concurrent presence of two thyroid carcinomas is rare. The simultaneous occurrence of two different tumors ...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s005950200112

    authors: Kösem M,Kotan C,Algün E,Topal C

    更新日期:2002-01-01 00:00:00

  • Fissurectomy with posterior midline sphincterotomy and anoplasty (FPSA) in the management of chronic anal fissures.

    abstract::Although lateral internal sphincterotomy is widely accepted as the treatment of choice for anal fissures, we report our experience of successfully treating 195 consecutive patients with posterior chronic anal fissures by performing fissurectomy with midline sphincterotomy and anoplasty (FPSA). The surgical technique i...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/BF02388152

    authors: Di Castro A,Biancari F,D'Andrea V,Caviglia A

    更新日期:1997-01-01 00:00:00

  • Separate functions of alpha2beta1 and alpha3beta1 integrins in the metastatic process of human gastric carcinoma.

    abstract::The expression of alpha2beta1 and alpha3beta1 integrins was studied immunohistochemically in 110 resected human gastric carcinomas. Formalin-fixed and paraffin-embedded samples were serially sectioned and stained with monoclonal antibodies specifically against the alpha2 and alpha3 subunits of beta1 integrins. Approxi...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/BF02483952

    authors: Ura H,Denno R,Hirata K,Yamaguchi K,Yasoshima T

    更新日期:1998-01-01 00:00:00

  • Occult gallbladder carcinoma diagnosed by a laparoscopic cholecystectomy.

    abstract:PURPOSE:A laparoscopic cholecystectomy (LC) has become a common treatment modality. The incidence of occult gallbladder carcinoma (GC) diagnosed by LC has increased; however, the effects of a radical second operation after LC have not yet been demonstrated. In this study we examine the outcome of such further surgical ...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-003-2596-1

    authors: Matsusaka S,Yamasaki H,Kitayama Y,Okada T,Maeda S

    更新日期:2003-01-01 00:00:00

  • Postradiation sarcoma of the chest wall: report of two cases.

    abstract::Postradiation sarcoma is a rare late complication of external radiotherapy. We herein present two cases with this disease. A 54-year-old man had undergone a lobectomy and chest wall resection for Pancoast type lung cancer 7 years previously. He had undergone irradiation with a total dose of 50 Gy. Computed tomography ...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-004-3300-9

    authors: Ninomiya H,Miyoshi T,Shirakusa T,Shiraishi T,Yamamoto N,Nabeshima K

    更新日期:2006-01-01 00:00:00

  • A prognostic index for colorectal cancer based on preoperative absolute lymphocyte, monocyte, and neutrophil counts.

    abstract:PURPOSE:Associations between the preoperative absolute neutrophil count (NC), lymphocyte count (LC), and monocyte count (MC) in the peripheral blood and the prognosis of colorectal cancer (CRC) patients have not been widely studied. METHODS:We enrolled 361 patients who underwent surgery for CRC between January 2007 an...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-018-1728-6

    authors: Tanio A,Saito H,Uejima C,Takaya S,Yamamoto M,Tokuyasu N,Sakamoto T,Honjo S,Ashida K,Fujiwara Y

    更新日期:2019-03-01 00:00:00

  • Limited thoracotomy for segmentectomy: a comparison of postoperative pain with thoracoscopic lobectomy.

    abstract:PURPOSES:To assess whether a video-assisted thoracoscopic surgery (VATS) procedure is superior to limited thoracotomy (LT) for segmentectomy; postoperative pain was compared between VATS-lobectomy (VATS-L) and LT-segmentectomy (LT-S). Widely opened anterolateral thoracotomy segmentectomy (WT-S) was used as a control. ...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-015-1302-4

    authors: Nomori H,Cong Y,Sugimura H

    更新日期:2016-11-01 00:00:00

  • Impact of microvessel density on lymph node metastasis and survival after curative resection of pancreatic cancer.

    abstract:PURPOSE:The roles of angiogenesis and the most prominent angiogenic vascular endothelial growth factor (VEGF) in diseases of the pancreas remain controversial. We compared microvessel density (MVD) and VEGF status in normal pancreatic, chronic pancreatic, and pancreatic cancer (PC) tissues to establish their prognostic...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-011-0045-0

    authors: Benckert C,Thelen A,Cramer T,Weichert W,Gaebelein G,Gessner R,Jonas S

    更新日期:2012-01-01 00:00:00

  • LINE-1 methylation level and prognosis in pancreas cancer: pyrosequencing technology and literature review.

    abstract:PURPOSE:Global DNA hypomethylation plays an important role in genomic instability and carcinogenesis. The long interspersed nucleotide element-1 (LINE-1) methylation level is a good surrogate marker of the global DNA methylation level. Previously, we demonstrated a strong relationship between LINE-1 hypomethylation and...

    journal_title:Surgery today

    pub_type: 杂志文章,评审

    doi:10.1007/s00595-017-1539-1

    authors: Yamamura K,Kosumi K,Baba Y,Harada K,Gao F,Zhang X,Zhou L,Kitano Y,Arima K,Kaida T,Takeyama H,Higashi T,Imai K,Hashimoto D,Chikamoto A,Tan X,Baba H

    更新日期:2017-12-01 00:00:00

  • Use of a gamma probe to identify and guide resection of recurrent parathyroid carcinoma: report of a case.

    abstract::Parathyroid carcinoma (PC) accounts for less than 0.005% of all cancers and less than 5% of causes of hyperparathyroidism. This tumor is difficult to identify during surgery, which is detrimental to the oncologic results. Surgery is still the main treatment for the primary tumor and to control parathyroid hormone leve...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-009-4233-0

    authors: Cruz RP,Padoin AV,Vilhordo DW,Hoffmann A,Mottin CC

    更新日期:2011-02-01 00:00:00

  • Phase III trial comparing UFT + PSK to UFT + LV in stage IIB, III colorectal cancer (MCSGO-CCTG).

    abstract:PURPOSE:Oral adjuvant uracil and tegafur plus leucovorin (UFT/LV) is not inferior to standard weekly fluorouracil and folinate for stage II/III colon cancer. However, protein-bound polysaccharide K (PSK) has been evaluated as postoperative adjuvant therapy for colorectal cancer. This report is the first of MCSGO-CCTG, ...

    journal_title:Surgery today

    pub_type: 杂志文章,多中心研究

    doi:10.1007/s00595-017-1555-1

    authors: Miyake Y,Nishimura J,Kato T,Ikeda M,Tsujie M,Hata T,Takemasa I,Mizushima T,Yamamoto H,Sekimoto M,Nezu R,Doki Y,Mori M,Multi-center Clinical Study Group of Osaka, Colorectal Cancer Treatment Group (MCSGO).

    更新日期:2018-01-01 00:00:00

  • The efficacy of active drainage for preventing postoperative organ/space surgical site infections in patients with Crohn's disease.

    abstract:PURPOSE:Patients with Crohn's disease (CD) show a higher incidence of surgical site infections (SSIs) after bowel resection in comparison to other patient populations because CD patients commonly suffer from anemia, malnutrition, and immunosuppression. In comparison to conventional passive drainage, active drainage usi...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-017-1549-z

    authors: Ikeshima R,Mizushima T,Takahashi H,Haraguchi N,Nishimura J,Hata T,Matsuda C,Ikenaga M,Nakajima K,Yamamoto H,Murata K,Doki Y,Mori M

    更新日期:2018-01-01 00:00:00