Some thoughts on assessing the effectiveness of passive immunization to Rh.

Abstract:

:In 1000 Rh-negative women who are delivered of Rh-positive fetuses and receive passive immunity postpartum, there will be 5-10 failures to protect against sensitization. Studies have been conducted to find out possible explanations for the failures and to devise means of preventing some or all of them. Results from the investigations indicate that if all postabortal and postpartum patients at risk receive anti-D immune globulin and are carefully screened for large fetomaternal bleeds by the use of direct counting of fetal red cells in the maternal circulation, the number of failures to protect against Rh sensitization can be reduced to an undiminishable minimum.

journal_name

Obstet Gynecol

authors

Johnson JS,Clayton EM Jr

subject

Has Abstract

pub_date

1974-04-01 00:00:00

pages

571-5

issue

4

eissn

0029-7844

issn

1873-233X

journal_volume

43

pub_type

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